BindingDB PrimarySearch

Found 10 hits with Last Name = 'barrachina' and Initial = 'i'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50510090 (CHEMBL4535730) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
University of Valencia Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in African green monkey COS7 cells assessed as increase in receptor transcriptional activity by lucifer...				J Nat Prod 82: 1802-1812 (2019) Article DOI: 10.1021/acs.jnatprod.9b00003 BindingDB Entry DOI: 10.7270/Q2ZW1Q7G
University of Valencia Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM24566 (2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...) Show SMILES Cc1cccc(Nc2cc(Cl)nc(SCC(O)=O)n2)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
University of Valencia Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in African green monkey COS7 cells assessed as increase in receptor transcriptional activity by lucifer...				J Nat Prod 82: 1802-1812 (2019) Article DOI: 10.1021/acs.jnatprod.9b00003 BindingDB Entry DOI: 10.7270/Q2ZW1Q7G
University of Valencia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50510090 (CHEMBL4535730) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
University of Valencia Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma expressed in African green monkey COS7 cells assessed as increase in receptor transcriptional activity by lucifer...				J Nat Prod 82: 1802-1812 (2019) Article DOI: 10.1021/acs.jnatprod.9b00003 BindingDB Entry DOI: 10.7270/Q2ZW1Q7G
University of Valencia Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50510091 (CHEMBL4519542) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a
University of Valencia Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma expressed in African green monkey COS7 cells assessed as increase in receptor transcriptional activity by lucifer...				J Nat Prod 82: 1802-1812 (2019) Article DOI: 10.1021/acs.jnatprod.9b00003 BindingDB Entry DOI: 10.7270/Q2ZW1Q7G
University of Valencia Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50510092 (CHEMBL4593987) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
University of Valencia Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma expressed in African green monkey COS7 cells assessed as increase in receptor transcriptional activity by lucifer...				J Nat Prod 82: 1802-1812 (2019) Article DOI: 10.1021/acs.jnatprod.9b00003 BindingDB Entry DOI: 10.7270/Q2ZW1Q7G
University of Valencia Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50510092 (CHEMBL4593987) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	184	n/a	n/a	n/a	n/a
University of Valencia Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in African green monkey COS7 cells assessed as increase in receptor transcriptional activity by lucifer...				J Nat Prod 82: 1802-1812 (2019) Article DOI: 10.1021/acs.jnatprod.9b00003 BindingDB Entry DOI: 10.7270/Q2ZW1Q7G
University of Valencia Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50510091 (CHEMBL4519542) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
University of Valencia Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in African green monkey COS7 cells assessed as increase in receptor transcriptional activity by lucifer...				J Nat Prod 82: 1802-1812 (2019) Article DOI: 10.1021/acs.jnatprod.9b00003 BindingDB Entry DOI: 10.7270/Q2ZW1Q7G
University of Valencia Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50510093 (CHEMBL4466552) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a
University of Valencia Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in African green monkey COS7 cells assessed as increase in receptor transcriptional activity by lucifer...				J Nat Prod 82: 1802-1812 (2019) Article DOI: 10.1021/acs.jnatprod.9b00003 BindingDB Entry DOI: 10.7270/Q2ZW1Q7G
University of Valencia Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50510094 (CHEMBL4460072) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	991	n/a	n/a	n/a	n/a
University of Valencia Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma expressed in African green monkey COS7 cells assessed as increase in receptor transcriptional activity by lucifer...				J Nat Prod 82: 1802-1812 (2019) Article DOI: 10.1021/acs.jnatprod.9b00003 BindingDB Entry DOI: 10.7270/Q2ZW1Q7G
University of Valencia Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50030474 (Avandamet \| Avandaryl \| Avandia \| BRL-49653 \| CHEB...) Show SMILES CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
University of Valencia Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma expressed in African green monkey COS7 cells assessed as increase in receptor transcriptional activity by lucifer...				J Nat Prod 82: 1802-1812 (2019) Article DOI: 10.1021/acs.jnatprod.9b00003 BindingDB Entry DOI: 10.7270/Q2ZW1Q7G
University of Valencia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)