Compile Data Set for Download or QSAR

Found 630 hits with Last Name = 'pilatte' and Initial = 'in'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335695 (US9737544, Compound 13) Show SMILES COc1cc(OC)cc(c1)C(CCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H24N4O3/c1-27-14-17(13-25-27)16-10-23-22(24-12-16)5-4-21(26-23)20(6-7-28)15-8-18(29-2)11-19(9-15)30-3/h4-5,8-14,20,28H,6-7H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335677 (US9737544, Compound 6) Show SMILES CNC(=O)\C=C(/c1cc(OC)cc(OC)c1)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H22N6O3/c1-24-22(30)10-18(14-7-16(31-3)9-17(8-14)32-4)19-5-6-20-23(27-19)28-21(12-25-20)15-11-26-29(2)13-15/h5-13H,1-4H3,(H,24,30)/b18-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335695 (US9737544, Compound 13) Show SMILES COc1cc(OC)cc(c1)C(CCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H24N4O3/c1-27-14-17(13-25-27)16-10-23-22(24-12-16)5-4-21(26-23)20(6-7-28)15-8-18(29-2)11-19(9-15)30-3/h4-5,8-14,20,28H,6-7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50.1	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335682 (US9737544, Compound 14) Show SMILES COc1cc(OC)cc(c1)C(CCO)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C22H23N5O3/c1-27-13-15(11-24-27)21-12-23-20-5-4-19(25-22(20)26-21)18(6-7-28)14-8-16(29-2)10-17(9-14)30-3/h4-5,8-13,18,28H,6-7H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335681 (US9737544, Compound 10) Show SMILES COc1cc(OC)cc(c1)C(O)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C21H20N4O3/c1-25-12-15(11-23-25)14-8-20-18(22-10-14)4-5-19(24-20)21(26)13-6-16(27-2)9-17(7-13)28-3/h4-12,21,26H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335680 (US9737544, Compound 9) Show SMILES CCOC(=O)CC(c1cc(OC)cc(OC)c1)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C25H26N4O4/c1-5-33-25(30)12-21(16-8-19(31-3)11-20(9-16)32-4)22-6-7-23-24(28-22)10-17(13-26-23)18-14-27-29(2)15-18/h6-11,13-15,21H,5,12H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335695 (US9737544, Compound 13) Show SMILES COc1cc(OC)cc(c1)C(CCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H24N4O3/c1-27-14-17(13-25-27)16-10-23-22(24-12-16)5-4-21(26-23)20(6-7-28)15-8-18(29-2)11-19(9-15)30-3/h4-5,8-14,20,28H,6-7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335677 (US9737544, Compound 6) Show SMILES CNC(=O)\C=C(/c1cc(OC)cc(OC)c1)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H22N6O3/c1-24-22(30)10-18(14-7-16(31-3)9-17(8-14)32-4)19-5-6-20-23(27-19)28-21(12-25-20)15-11-26-29(2)13-15/h5-13H,1-4H3,(H,24,30)/b18-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335680 (US9737544, Compound 9) Show SMILES CCOC(=O)CC(c1cc(OC)cc(OC)c1)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C25H26N4O4/c1-5-33-25(30)12-21(16-8-19(31-3)11-20(9-16)32-4)22-6-7-23-24(28-22)10-17(13-26-23)18-14-27-29(2)15-18/h6-11,13-15,21H,5,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM335686 (US9737544, Compound 18) Show SMILES Cn1cc(cn1)-c1cnc2ccc(nc2c1)C(=O)c1cccc(O)c1 Show InChI InChI=1S/C19H14N4O2/c1-23-11-14(10-21-23)13-8-18-16(20-9-13)5-6-17(22-18)19(25)12-3-2-4-15(24)7-12/h2-11,24H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trito...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335677 (US9737544, Compound 6) Show SMILES CNC(=O)\C=C(/c1cc(OC)cc(OC)c1)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H22N6O3/c1-24-22(30)10-18(14-7-16(31-3)9-17(8-14)32-4)19-5-6-20-23(27-19)28-21(12-25-20)15-11-26-29(2)13-15/h5-13H,1-4H3,(H,24,30)/b18-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335681 (US9737544, Compound 10) Show SMILES COc1cc(OC)cc(c1)C(O)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C21H20N4O3/c1-25-12-15(11-23-25)14-8-20-18(22-10-14)4-5-19(24-20)21(26)13-6-16(27-2)9-17(7-13)28-3/h4-12,21,26H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335681 (US9737544, Compound 10) Show SMILES COc1cc(OC)cc(c1)C(O)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C21H20N4O3/c1-25-12-15(11-23-25)14-8-20-18(22-10-14)4-5-19(24-20)21(26)13-6-16(27-2)9-17(7-13)28-3/h4-12,21,26H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335682 (US9737544, Compound 14) Show SMILES COc1cc(OC)cc(c1)C(CCO)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C22H23N5O3/c1-27-13-15(11-24-27)21-12-23-20-5-4-19(25-22(20)26-21)18(6-7-28)14-8-16(29-2)10-17(9-14)30-3/h4-5,8-13,18,28H,6-7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335679 (US9737544, Compound 8) Show SMILES COc1cc(OC)cc(c1)C(=O)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C21H18N4O3/c1-25-12-15(11-23-25)14-8-20-18(22-10-14)4-5-19(24-20)21(26)13-6-16(27-2)9-17(7-13)28-3/h4-12H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335680 (US9737544, Compound 9) Show SMILES CCOC(=O)CC(c1cc(OC)cc(OC)c1)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C25H26N4O4/c1-5-33-25(30)12-21(16-8-19(31-3)11-20(9-16)32-4)22-6-7-23-24(28-22)10-17(13-26-23)18-14-27-29(2)15-18/h6-11,13-15,21H,5,12H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335679 (US9737544, Compound 8) Show SMILES COc1cc(OC)cc(c1)C(=O)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C21H18N4O3/c1-25-12-15(11-23-25)14-8-20-18(22-10-14)4-5-19(24-20)21(26)13-6-16(27-2)9-17(7-13)28-3/h4-12H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335686 (US9737544, Compound 18) Show SMILES Cn1cc(cn1)-c1cnc2ccc(nc2c1)C(=O)c1cccc(O)c1 Show InChI InChI=1S/C19H14N4O2/c1-23-11-14(10-21-23)13-8-18-16(20-9-13)5-6-17(22-18)19(25)12-3-2-4-15(24)7-12/h2-11,24H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335696 (US9737544, Compound 11) Show SMILES COc1cc(OC)cc(c1)C(OCCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H24N4O4/c1-27-14-17(13-25-27)16-10-22-20(24-12-16)4-5-21(26-22)23(31-7-6-28)15-8-18(29-2)11-19(9-15)30-3/h4-5,8-14,23,28H,6-7H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335673 (US9737544, Compound 2) Show SMILES COc1cc(OC)cc(c1)C(O)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C20H19N5O3/c1-25-11-13(9-22-25)18-10-21-17-5-4-16(23-20(17)24-18)19(26)12-6-14(27-2)8-15(7-12)28-3/h4-11,19,26H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335696 (US9737544, Compound 11) Show SMILES COc1cc(OC)cc(c1)C(OCCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H24N4O4/c1-27-14-17(13-25-27)16-10-22-20(24-12-16)4-5-21(26-22)23(31-7-6-28)15-8-18(29-2)11-19(9-15)30-3/h4-5,8-14,23,28H,6-7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM335695 (US9737544, Compound 13) Show SMILES COc1cc(OC)cc(c1)C(CCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H24N4O3/c1-27-14-17(13-25-27)16-10-23-22(24-12-16)5-4-21(26-23)20(6-7-28)15-8-18(29-2)11-19(9-15)30-3/h4-5,8-14,20,28H,6-7H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335686 (US9737544, Compound 18) Show SMILES Cn1cc(cn1)-c1cnc2ccc(nc2c1)C(=O)c1cccc(O)c1 Show InChI InChI=1S/C19H14N4O2/c1-23-11-14(10-21-23)13-8-18-16(20-9-13)5-6-17(22-18)19(25)12-3-2-4-15(24)7-12/h2-11,24H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335678 (US9737544, Compound 7) Show SMILES CNC(=O)\C=C(\c1cc(OC)cc(OC)c1)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H22N6O3/c1-24-22(30)10-18(14-7-16(31-3)9-17(8-14)32-4)19-5-6-20-23(27-19)28-21(12-25-20)15-11-26-29(2)13-15/h5-13H,1-4H3,(H,24,30)/b18-10-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM335677 (US9737544, Compound 6) Show SMILES CNC(=O)\C=C(/c1cc(OC)cc(OC)c1)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H22N6O3/c1-24-22(30)10-18(14-7-16(31-3)9-17(8-14)32-4)19-5-6-20-23(27-19)28-21(12-25-20)15-11-26-29(2)13-15/h5-13H,1-4H3,(H,24,30)/b18-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trito...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335678 (US9737544, Compound 7) Show SMILES CNC(=O)\C=C(\c1cc(OC)cc(OC)c1)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H22N6O3/c1-24-22(30)10-18(14-7-16(31-3)9-17(8-14)32-4)19-5-6-20-23(27-19)28-21(12-25-20)15-11-26-29(2)13-15/h5-13H,1-4H3,(H,24,30)/b18-10-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335682 (US9737544, Compound 14) Show SMILES COc1cc(OC)cc(c1)C(CCO)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C22H23N5O3/c1-27-13-15(11-24-27)21-12-23-20-5-4-19(25-22(20)26-21)18(6-7-28)14-8-16(29-2)10-17(9-14)30-3/h4-5,8-13,18,28H,6-7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335679 (US9737544, Compound 8) Show SMILES COc1cc(OC)cc(c1)C(=O)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C21H18N4O3/c1-25-12-15(11-23-25)14-8-20-18(22-10-14)4-5-19(24-20)21(26)13-6-16(27-2)9-17(7-13)28-3/h4-12H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335675 (US9737544, Compound 4) Show SMILES COC(=O)CC(c1cc(OC)cc(OC)c1)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H23N5O4/c1-28-13-15(11-25-28)21-12-24-20-6-5-19(26-23(20)27-21)18(10-22(29)32-4)14-7-16(30-2)9-17(8-14)31-3/h5-9,11-13,18H,10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335684 (US9737544, Compound 16) Show SMILES COc1cccc(c1)C(=O)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C20H16N4O2/c1-24-12-15(11-22-24)14-9-19-17(21-10-14)6-7-18(23-19)20(25)13-4-3-5-16(8-13)26-2/h3-12H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335678 (US9737544, Compound 7) Show SMILES CNC(=O)\C=C(\c1cc(OC)cc(OC)c1)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H22N6O3/c1-24-22(30)10-18(14-7-16(31-3)9-17(8-14)32-4)19-5-6-20-23(27-19)28-21(12-25-20)15-11-26-29(2)13-15/h5-13H,1-4H3,(H,24,30)/b18-10-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335675 (US9737544, Compound 4) Show SMILES COC(=O)CC(c1cc(OC)cc(OC)c1)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H23N5O4/c1-28-13-15(11-25-28)21-12-24-20-6-5-19(26-23(20)27-21)18(10-22(29)32-4)14-7-16(30-2)9-17(8-14)31-3/h5-9,11-13,18H,10H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM335677 (US9737544, Compound 6) Show SMILES CNC(=O)\C=C(/c1cc(OC)cc(OC)c1)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H22N6O3/c1-24-22(30)10-18(14-7-16(31-3)9-17(8-14)32-4)19-5-6-20-23(27-19)28-21(12-25-20)15-11-26-29(2)13-15/h5-13H,1-4H3,(H,24,30)/b18-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM335680 (US9737544, Compound 9) Show SMILES CCOC(=O)CC(c1cc(OC)cc(OC)c1)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C25H26N4O4/c1-5-33-25(30)12-21(16-8-19(31-3)11-20(9-16)32-4)22-6-7-23-24(28-22)10-17(13-26-23)18-14-27-29(2)15-18/h6-11,13-15,21H,5,12H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trito...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335697 (US9737544, Compound 15) Show SMILES COc1cc(OC)cc(c1)C(Cc1nccn1S(=O)(=O)N(C)C)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C26H28N8O4S/c1-32(2)39(35,36)34-9-8-27-25(34)13-21(17-10-19(37-4)12-20(11-17)38-5)22-6-7-23-26(30-22)31-24(15-28-23)18-14-29-33(3)16-18/h6-12,14-16,21H,13H2,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335673 (US9737544, Compound 2) Show SMILES COc1cc(OC)cc(c1)C(O)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C20H19N5O3/c1-25-11-13(9-22-25)18-10-21-17-5-4-16(23-20(17)24-18)19(26)12-6-14(27-2)8-15(7-12)28-3/h4-11,19,26H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335697 (US9737544, Compound 15) Show SMILES COc1cc(OC)cc(c1)C(Cc1nccn1S(=O)(=O)N(C)C)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C26H28N8O4S/c1-32(2)39(35,36)34-9-8-27-25(34)13-21(17-10-19(37-4)12-20(11-17)38-5)22-6-7-23-26(30-22)31-24(15-28-23)18-14-29-33(3)16-18/h6-12,14-16,21H,13H2,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335696 (US9737544, Compound 11) Show SMILES COc1cc(OC)cc(c1)C(OCCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H24N4O4/c1-27-14-17(13-25-27)16-10-22-20(24-12-16)4-5-21(26-22)23(31-7-6-28)15-8-18(29-2)11-19(9-15)30-3/h4-5,8-14,23,28H,6-7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM335695 (US9737544, Compound 13) Show SMILES COc1cc(OC)cc(c1)C(CCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H24N4O3/c1-27-14-17(13-25-27)16-10-23-22(24-12-16)5-4-21(26-23)20(6-7-28)15-8-18(29-2)11-19(9-15)30-3/h4-5,8-14,20,28H,6-7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trito...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM335681 (US9737544, Compound 10) Show SMILES COc1cc(OC)cc(c1)C(O)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C21H20N4O3/c1-25-12-15(11-23-25)14-8-20-18(22-10-14)4-5-19(24-20)21(26)13-6-16(27-2)9-17(7-13)28-3/h4-12,21,26H,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM335682 (US9737544, Compound 14) Show SMILES COc1cc(OC)cc(c1)C(CCO)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C22H23N5O3/c1-27-13-15(11-24-27)21-12-23-20-5-4-19(25-22(20)26-21)18(6-7-28)14-8-16(29-2)10-17(9-14)30-3/h4-5,8-13,18,28H,6-7H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335697 (US9737544, Compound 15) Show SMILES COc1cc(OC)cc(c1)C(Cc1nccn1S(=O)(=O)N(C)C)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C26H28N8O4S/c1-32(2)39(35,36)34-9-8-27-25(34)13-21(17-10-19(37-4)12-20(11-17)38-5)22-6-7-23-26(30-22)31-24(15-28-23)18-14-29-33(3)16-18/h6-12,14-16,21H,13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335686 (US9737544, Compound 18) Show SMILES Cn1cc(cn1)-c1cnc2ccc(nc2c1)C(=O)c1cccc(O)c1 Show InChI InChI=1S/C19H14N4O2/c1-23-11-14(10-21-23)13-8-18-16(20-9-13)5-6-17(22-18)19(25)12-3-2-4-15(24)7-12/h2-11,24H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM335685 (US9737544, Compound 17) Show SMILES COc1cccc(c1)C(O)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C20H18N4O2/c1-24-12-15(11-22-24)14-9-19-17(21-10-14)6-7-18(23-19)20(25)13-4-3-5-16(8-13)26-2/h3-12,20,25H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335673 (US9737544, Compound 2) Show SMILES COc1cc(OC)cc(c1)C(O)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C20H19N5O3/c1-25-11-13(9-22-25)18-10-21-17-5-4-16(23-20(17)24-18)19(26)12-6-14(27-2)8-15(7-12)28-3/h4-11,19,26H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335675 (US9737544, Compound 4) Show SMILES COC(=O)CC(c1cc(OC)cc(OC)c1)c1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H23N5O4/c1-28-13-15(11-25-28)21-12-24-20-6-5-19(26-23(20)27-21)18(10-22(29)32-4)14-7-16(30-2)9-17(8-14)31-3/h5-9,11-13,18H,10H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335685 (US9737544, Compound 17) Show SMILES COc1cccc(c1)C(O)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C20H18N4O2/c1-24-12-15(11-22-24)14-9-19-17(21-10-14)6-7-18(23-19)20(25)13-4-3-5-16(8-13)26-2/h3-12,20,25H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM335685 (US9737544, Compound 17) Show SMILES COc1cccc(c1)C(O)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C20H18N4O2/c1-24-12-15(11-22-24)14-9-19-17(21-10-14)6-7-18(23-19)20(25)13-4-3-5-16(8-13)26-2/h3-12,20,25H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trito...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM335689 (US9737544, Compound 23) Show SMILES COc1cc(OC)cc(c1)C(=O)c1cc2cc(cnc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C21H18N4O3/c1-25-12-16(10-24-25)15-4-13-7-19(23-11-20(13)22-9-15)21(26)14-5-17(27-2)8-18(6-14)28-3/h4-12H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM335689 (US9737544, Compound 23) Show SMILES COc1cc(OC)cc(c1)C(=O)c1cc2cc(cnc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C21H18N4O3/c1-25-12-16(10-24-25)15-4-13-7-19(23-11-20(13)22-9-15)21(26)14-5-17(27-2)8-18(6-14)28-3/h4-12H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...				US Patent US9737544 (2017) BindingDB Entry DOI: 10.7270/Q2H70HZF
					More data for this Ligand-Target Pair

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