Compile Data Set for Download or QSAR

Found 1779 hits with Last Name = 'kuehler' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601067 (CHEMBL5208088 | US11702418, Example 6-4) Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCNCC1)c1cccc(c1C)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601075 (CHEMBL5202472 | US11702418, Example 6-9) Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCNCC1)c1cccc(c1C)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601069 (CHEMBL5191446 | US11702418, Example 6-7) Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N1CCN(C)C(=O)C1)c1cccc(c1C)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601065 (CHEMBL5206295 | US11702418, Example 4-4) Show SMILES CNCc1ccccc1-c1csc(c1)[C@@H](C)Nc1nnc(C)c2cc(OC)c(OC)cc12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601076 (CHEMBL5209371 | US11702418, Example 6-12) Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCOCC1)c1cccc(c1C)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601072 (CHEMBL5176365 | US11702418, Example 9-2) Show SMILES C[C@@H](Nc1nnc(N(C)C)c2ccc(cc12)N1CCNCC1)c1cccc(c1C)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601083 (CHEMBL5193021) Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCOCC1)c1cccc(Br)c1C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601084 (CHEMBL5192659 | US11702418, Example 12-10) Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCOCC1)c1cccc(C#N)c1C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601066 (CHEMBL5179610 | US11702418, Example 10-45) Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)N(C)C)c1cccc(c1C)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601085 (CHEMBL5198950 | US11702418, Example 6-19) Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCOCC1)c1cccc(c1C)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601091 (CHEMBL5171096 | US11702418, Example 4-1) Show SMILES COc1cc2c(C)nnc(N[C@H](C)c3cccc(c3C)C(F)(F)F)c2cc1OC |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601077 (CHEMBL5176509 | US11702418, Example 12-50) Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCOCC1)c1cccc(c1F)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601068 (CHEMBL5176696) Show SMILES C[C@@H](Nc1nnc(C)c2ccc(cc12)C1CCNCC1)c1cccc(c1C)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601064 (CHEMBL5174300 | US11702418, Example 1-14) Show SMILES CNCc1ccccc1-c1csc(c1)[C@@H](C)Nc1nncc2cc(OC)c(OC)cc12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601086 (CHEMBL5186883 | US11702418, Example 6-16) Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCOCC1)c1cccc(c1)C#N |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601073 (CHEMBL5193110) Show SMILES C[C@@H](Nc1n[nH]c(=O)c2ccc(cc12)N1CCNCC1)c1cccc(c1C)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601079 (CHEMBL5191745 | US11702418, Example 16-3) Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCOCC1)c1cc(N)cc(n1)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601063 (CHEMBL5202863 | US11702418, Example 1-13) Show SMILES COc1cc2cnnc(N[C@H](C)c3cccc(c3C)C(F)(F)F)c2cc1OC |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601089 (CHEMBL5198132) Show SMILES C[C@@H](Nc1nnc(C)c2cc(C#N)c(cc12)N1CCOCC1)c1cccc(C#N)c1C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601088 (CHEMBL5182064) Show SMILES C[C@@H](Nc1nnc(C)c2cc(Cl)c(cc12)N1CCOCC1)c1cccc(C#N)c1C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601087 (CHEMBL5187475) Show SMILES C[C@@H](Nc1nnc(C)c2cc(F)c(cc12)N1CCOCC1)c1cccc(C#N)c1C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601074 (CHEMBL5198767) Show SMILES C[C@@H](Nc1nn(C)c(=O)c2ccc(cc12)N1CCNCC1)c1cccc(c1C)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601078 (CHEMBL5203468) Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCOCC1)c1cccc(n1)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601080 (CHEMBL5207802 | US11702418, Example 12-41) Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCOCC1)c1cccnc1C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601061 (CHEMBL5169564) Show SMILES COc1cc2cnnc(N[C@H](C)c3cccc(c3)C(F)(F)F)c2cc1OC |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601082 (CHEMBL5190699) Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCOCC1)c1cn(C)nc1C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601070 (CHEMBL5183207) Show SMILES C[C@@H](Nc1nnc(c2ccc(cc12)N1CCNCC1)C(F)(F)F)c1cccc(c1C)C(F)(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601060 (CHEMBL5200949) Show SMILES COc1cc2cnnc(N[C@H](C)c3cccc4ccccc34)c2cc1OC |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601090 (CHEMBL5185048 | US11702418, Example 19-2) Show SMILES C[C@@H](Nc1nnc(C)c2cc(c(cc12)N1CCOCC1)C(F)(F)F)c1cccc(C#N)c1C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601071 (CHEMBL5199603) Show SMILES COc1nnc(N[C@H](C)c2cccc(c2C)C(F)(F)F)c2cc(ccc12)N1CCNCC1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601059 (CHEMBL5200875) Show SMILES COc1cc2cnnc(N[C@H](C)c3ccccc3)c2cc1OC |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	637	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601081 (CHEMBL5195217) Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1CCOCC1)c1cn(C)nc1C |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Son of sevenless homolog 1 (Homo sapiens (Human))	BDBM50601062 (CHEMBL5183547) Show SMILES COc1cc2cnnc(N[C@H](C)c3ccccc3C)c2cc1OC |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00741 BindingDB Entry DOI: 10.7270/Q2XD15Q0
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578799 (4-(aminomethyl)-6-(4-benzyl-4H-1,2,4-triazol-3- yl...) Show SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1nncn1Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578810 (4-(aminomethyl)-6-(1-methyl-3-(trifluoromethyl)-1H...) Show SMILES Cn1nc(cc1-c1ccc2c(c1)c(CN)n[nH]c2=O)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578828 (4-(aminomethyl)-6-(1-methyl-1H-pyrrolo[2,3-b]pyrid...) Show SMILES Cn1cc(-c2ccc3c(c2)c(CN)n[nH]c3=O)c2cccnc12 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578954 (US11479551, Example 13-1 | US11479551, Example 6-2...) Show SMILES Brc1ccc2c(CN3C(=O)c4ccccc4C3=O)n[nH]c(=O)c2c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578954 (US11479551, Example 13-1 | US11479551, Example 6-2...) Show SMILES Brc1ccc2c(CN3C(=O)c4ccccc4C3=O)n[nH]c(=O)c2c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578799 (4-(aminomethyl)-6-(4-benzyl-4H-1,2,4-triazol-3- yl...) Show SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1nncn1Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578810 (4-(aminomethyl)-6-(1-methyl-3-(trifluoromethyl)-1H...) Show SMILES Cn1nc(cc1-c1ccc2c(c1)c(CN)n[nH]c2=O)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578828 (4-(aminomethyl)-6-(1-methyl-1H-pyrrolo[2,3-b]pyrid...) Show SMILES Cn1cc(-c2ccc3c(c2)c(CN)n[nH]c3=O)c2cccnc12 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578831 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES COc1cccc(-c2c(cnn2C)-c2ccc3c(c2)c(CN)n[nH]c3=O)c1C#N |(-6.5,-1.85,;-5.41,-2.93,;-3.92,-2.54,;-2.83,-3.62,;-1.34,-3.23,;-.95,-1.74,;-2.03,-.65,;-1.64,.84,;-.17,1.31,;-.17,2.85,;-1.64,3.33,;-2.54,2.08,;-4.08,2.08,;1.16,.54,;1.16,-1,;2.5,-1.77,;3.83,-1,;3.83,.54,;2.5,1.31,;5.16,1.31,;5.16,2.85,;6.5,3.62,;6.5,.54,;6.5,-1,;5.16,-1.77,;5.16,-3.31,;-3.52,-1.05,;-4.61,.04,;-5.7,1.13,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578823 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cn1ncc(c1-c1cc(Cl)ccc1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O |(-4.48,2.43,;-2.94,2.43,;-2.03,3.68,;-.57,3.2,;-.57,1.66,;-2.03,1.18,;-2.43,-.3,;-1.34,-1.39,;-1.74,-2.88,;-.65,-3.97,;-3.23,-3.28,;-4.32,-2.19,;-3.92,-.7,;-5.01,.39,;-6.1,1.48,;.76,.89,;.76,-.65,;2.1,-1.42,;3.43,-.65,;3.43,.89,;2.1,1.66,;4.76,1.66,;4.76,3.2,;6.1,3.97,;6.1,.89,;6.1,-.65,;4.76,-1.42,;4.76,-2.96,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578829 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cc1ccc(-c2c(cnn2C)-c2ccc3c(c2)c(CN)n[nH]c3=O)c(c1)C#N |(-3.63,-4.37,;-3.23,-2.88,;-1.74,-2.48,;-1.34,-.99,;-2.43,.09,;-2.03,1.58,;-.57,2.06,;-.57,3.6,;-2.03,4.07,;-2.94,2.83,;-4.48,2.83,;.76,1.29,;.76,-.25,;2.1,-1.02,;3.43,-.25,;3.43,1.29,;2.1,2.06,;4.76,2.06,;4.76,3.6,;6.1,4.37,;6.1,1.29,;6.1,-.25,;4.76,-1.02,;4.76,-2.56,;-3.92,-.3,;-4.32,-1.79,;-5.01,.78,;-6.1,1.87,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578825 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES COc1ccc(C#N)c(c1)-c1c(cnn1C)-c1ccc2c(c1)c(CN)n[nH]c2=O |(.83,-3.57,;-.65,-3.97,;-1.74,-2.88,;-3.23,-3.28,;-4.32,-2.19,;-3.92,-.7,;-5.01,.39,;-6.1,1.48,;-2.43,-.3,;-1.34,-1.39,;-2.03,1.18,;-.57,1.66,;-.57,3.2,;-2.03,3.68,;-2.94,2.43,;-4.48,2.43,;.76,.89,;.76,-.65,;2.1,-1.42,;3.43,-.65,;3.43,.89,;2.1,1.66,;4.76,1.66,;4.76,3.2,;6.1,3.97,;6.1,.89,;6.1,-.65,;4.76,-1.42,;4.76,-2.96,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q23F4SWQ
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578895 (4-(aminomethyl)-6-(5-(2- methoxyphenoxy)pyridin-3-...) Show SMILES COc1ccccc1Oc1cncc(c1)-c1ccc2c(c1)c(CN)n[nH]c2=O Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578819 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cn1ncc(c1-c1ccccc1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O |(-4.48,2.08,;-2.94,2.08,;-2.03,3.33,;-.57,2.85,;-.57,1.31,;-2.03,.84,;-2.43,-.65,;-1.34,-1.74,;-1.74,-3.23,;-3.23,-3.62,;-4.32,-2.54,;-3.92,-1.05,;-5.01,.04,;-6.1,1.13,;.76,.54,;.76,-1,;2.1,-1.77,;3.43,-1,;3.43,.54,;2.1,1.31,;4.76,1.31,;4.76,2.85,;3.43,3.62,;6.1,.54,;6.1,-1,;4.76,-1.77,;4.76,-3.31,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578821 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cn1ncc(c1-c1ccc(Cl)cc1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O |(-4.48,2.83,;-2.94,2.83,;-2.03,4.07,;-.57,3.6,;-.57,2.06,;-2.03,1.58,;-2.43,.09,;-1.34,-.99,;-1.74,-2.48,;-3.23,-2.88,;-3.63,-4.37,;-4.32,-1.79,;-3.92,-.3,;-5.01,.78,;-6.1,1.87,;.76,1.29,;.76,-.25,;2.1,-1.02,;3.43,-.25,;3.43,1.29,;2.1,2.06,;4.76,2.06,;4.76,3.6,;6.1,4.37,;6.1,1.29,;6.1,-.25,;4.76,-1.02,;4.76,-2.56,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578823 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES Cn1ncc(c1-c1cc(Cl)ccc1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O |(-4.48,2.43,;-2.94,2.43,;-2.03,3.68,;-.57,3.2,;-.57,1.66,;-2.03,1.18,;-2.43,-.3,;-1.34,-1.39,;-1.74,-2.88,;-.65,-3.97,;-3.23,-3.28,;-4.32,-2.19,;-3.92,-.7,;-5.01,.39,;-6.1,1.48,;.76,.89,;.76,-.65,;2.1,-1.42,;3.43,-.65,;3.43,.89,;2.1,1.66,;4.76,1.66,;4.76,3.2,;6.1,3.97,;6.1,.89,;6.1,-.65,;4.76,-1.42,;4.76,-2.96,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM578825 (2-(4-(4-(aminomethyl)-1-oxo-1,2- dihydrophthalazin...) Show SMILES COc1ccc(C#N)c(c1)-c1c(cnn1C)-c1ccc2c(c1)c(CN)n[nH]c2=O |(.83,-3.57,;-.65,-3.97,;-1.74,-2.88,;-3.23,-3.28,;-4.32,-2.19,;-3.92,-.7,;-5.01,.39,;-6.1,1.48,;-2.43,-.3,;-1.34,-1.39,;-2.03,1.18,;-.57,1.66,;-.57,3.2,;-2.03,3.68,;-2.94,2.43,;-4.48,2.43,;.76,.89,;.76,-.65,;2.1,-1.42,;3.43,-.65,;3.43,.89,;2.1,1.66,;4.76,1.66,;4.76,3.2,;6.1,3.97,;6.1,.89,;6.1,-.65,;4.76,-1.42,;4.76,-2.96,)| Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V128N9
					More data for this Ligand-Target Pair

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