Compile Data Set for Download or QSAR

Found 21 hits with Last Name = 'olney' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015743 (Acetic acid 3-[1-(3,6-dihydro-2H-pyridin-1-yl)-cyc...) Show SMILES CC(=O)Oc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:21| Show InChI InChI=1S/C19H25NO2/c1-16(21)22-18-10-8-9-17(15-18)19(11-4-2-5-12-19)20-13-6-3-7-14-20/h3,6,8-10,15H,2,4-5,7,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015738 (3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-phe...) Show SMILES Oc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:18| Show InChI InChI=1S/C17H23NO/c19-16-9-7-8-15(14-16)17(10-3-1-4-11-17)18-12-5-2-6-13-18/h2,5,7-9,14,19H,1,3-4,6,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM86495 (EAB-318) Show SMILES N[C@H](Cc1nc2cc(Cl)ccc2n1P(O)(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11ClN3O5P/c11-5-1-2-8-7(3-5)13-9(4-6(12)10(15)16)14(8)20(17,18)19/h1-3,6H,4,12H2,(H,15,16)(H2,17,18,19)/t6-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 310: 563-70 (2004) Article DOI: 10.1124/jpet.104.066092 BindingDB Entry DOI: 10.7270/Q2DJ5D6D
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015734 (1-(1-Thiophen-2-yl-cyclohexyl)-1,2,3,6-tetrahydro-...) Show SMILES C1CCC(CC1)(N1CCC=CC1)c1cccs1 |c:10| Show InChI InChI=1S/C15H21NS/c1-3-9-15(10-4-1,14-8-7-13-17-14)16-11-5-2-6-12-16/h2,5,7-8,13H,1,3-4,6,9-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM86494 (EAA-090 | Perzinfotel | WAY-126090) Show SMILES [#8][P;v5]([#8])(=O)[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#7]-c2c-1c(=O)c2=O Show InChI InChI=1S/C9H13N2O5P/c12-8-6-7(9(8)13)11(3-1-2-10-6)4-5-17(14,15)16/h10H,1-5H2,(H2,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 310: 563-70 (2004) Article DOI: 10.1124/jpet.104.066092 BindingDB Entry DOI: 10.7270/Q2DJ5D6D
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015741 (1-[1-(3-Methoxy-phenyl)-cyclohexyl]-1,2,3,6-tetrah...) Show SMILES COc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:19| Show InChI InChI=1S/C18H25NO/c1-20-17-10-8-9-16(15-17)18(11-4-2-5-12-18)19-13-6-3-7-14-19/h3,6,8-10,15H,2,4-5,7,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015732 (1-(1-Phenyl-cyclohexyl)-1,2,3,6-tetrahydro-pyridin...) Show SMILES C1CCC(CC1)(N1CCC=CC1)c1ccccc1 |c:10| Show InChI InChI=1S/C17H23N/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18/h1,3-5,8,10-11H,2,6-7,9,12-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015733 (3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-ben...) Show SMILES O=NCc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:20| Show InChI InChI=1S/C18H24N2O/c21-19-15-16-8-7-9-17(14-16)18(10-3-1-4-11-18)20-12-5-2-6-13-20/h2,5,7-9,14H,1,3-4,6,10-13,15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015735 (1-(1-m-Tolyl-cyclohexyl)-1,2,3,6-tetrahydro-pyridi...) Show SMILES Cc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:18| Show InChI InChI=1S/C18H25N/c1-16-9-8-10-17(15-16)18(11-4-2-5-12-18)19-13-6-3-7-14-19/h3,6,8-10,15H,2,4-5,7,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015744 (1-[1-(3-Methoxymethoxy-phenyl)-cyclohexyl]-1,2,3,6...) Show SMILES COCOc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:21| Show InChI InChI=1S/C19H27NO2/c1-21-16-22-18-10-8-9-17(15-18)19(11-4-2-5-12-19)20-13-6-3-7-14-20/h3,6,8-10,15H,2,4-5,7,11-14,16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015740 (1-[1-(3-Vinyl-phenyl)-cyclohexyl]-1,2,3,6-tetrahyd...) Show SMILES C=Cc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:19| Show InChI InChI=1S/C19H25N/c1-2-17-10-9-11-18(16-17)19(12-5-3-6-13-19)20-14-7-4-8-15-20/h2,4,7,9-11,16H,1,3,5-6,8,12-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015731 (1-[1-(3-Methylsulfanyl-phenyl)-cyclohexyl]-1,2,3,6...) Show SMILES CSc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:19| Show InChI InChI=1S/C18H25NS/c1-20-17-10-8-9-16(15-17)18(11-4-2-5-12-18)19-13-6-3-7-14-19/h3,6,8-10,15H,2,4-5,7,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	231	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015736 (1-[1-(3-Fluoro-phenyl)-cyclohexyl]-1,2,3,6-tetrahy...) Show SMILES Fc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:18| Show InChI InChI=1S/C17H22FN/c18-16-9-7-8-15(14-16)17(10-3-1-4-11-17)19-12-5-2-6-13-19/h2,5,7-9,14H,1,3-4,6,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	281	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015739 (3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-ben...) Show SMILES O=Cc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:19| Show InChI InChI=1S/C18H23NO/c20-15-16-8-7-9-17(14-16)18(10-3-1-4-11-18)19-12-5-2-6-13-19/h2,5,7-9,14-15H,1,3-4,6,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	324	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015730 (1-[1-(3-Trifluoromethyl-phenyl)-cyclohexyl]-1,2,3,...) Show SMILES FC(F)(F)c1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:21| Show InChI InChI=1S/C18H22F3N/c19-18(20,21)16-9-7-8-15(14-16)17(10-3-1-4-11-17)22-12-5-2-6-13-22/h2,5,7-9,14H,1,3-4,6,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	422	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015742 (1-[1-(3-[1,3]Dioxolan-2-yl-phenyl)-cyclohexyl]-1,2...) Show SMILES C1COC(O1)c1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:23| Show InChI InChI=1S/C20H27NO2/c1-3-10-20(11-4-1,21-12-5-2-6-13-21)18-9-7-8-17(16-18)19-22-14-15-23-19/h2,5,7-9,16,19H,1,3-4,6,10-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	601	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM86495 (EAB-318) Show SMILES N[C@H](Cc1nc2cc(Cl)ccc2n1P(O)(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11ClN3O5P/c11-5-1-2-8-7(3-5)13-9(4-6(12)10(15)16)14(8)20(17,18)19/h1-3,6H,4,12H2,(H,15,16)(H2,17,18,19)/t6-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	719	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 310: 563-70 (2004) Article DOI: 10.1124/jpet.104.066092 BindingDB Entry DOI: 10.7270/Q2DJ5D6D
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015745 (1-[1-(3-Benzyloxy-phenyl)-cyclohexyl]-1,2,3,6-tetr...) Show SMILES C(Oc1cccc(c1)C1(CCCCC1)N1CCC=CC1)c1ccccc1 |c:19| Show InChI InChI=1S/C24H29NO/c1-4-11-21(12-5-1)20-26-23-14-10-13-22(19-23)24(15-6-2-7-16-24)25-17-8-3-9-18-25/h1,3-5,8,10-14,19H,2,6-7,9,15-18,20H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	733	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM86494 (EAA-090 | Perzinfotel | WAY-126090) Show SMILES [#8][P;v5]([#8])(=O)[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#7]-c2c-1c(=O)c2=O Show InChI InChI=1S/C9H13N2O5P/c12-8-6-7(9(8)13)11(3-1-2-10-6)4-5-17(14,15)16/h10H,1-5H2,(H2,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 310: 563-70 (2004) Article DOI: 10.1124/jpet.104.066092 BindingDB Entry DOI: 10.7270/Q2DJ5D6D
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015737 (1-[1-(3,5-Dimethoxy-phenyl)-cyclohexyl]-1,2,3,6-te...) Show SMILES COc1cc(OC)cc(c1)C1(CCCCC1)N1CCC=CC1 |c:21| Show InChI InChI=1S/C19H27NO2/c1-21-17-13-16(14-18(15-17)22-2)19(9-5-3-6-10-19)20-11-7-4-8-12-20/h4,7,13-15H,3,5-6,8-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50004927 (4-Phosphonomethyl-piperidine-2-carboxylic acid | 4...) Show SMILES OC(=O)[C@@H]1C[C@H](CP(O)(O)=O)CCN1 Show InChI InChI=1S/C7H14NO5P/c9-7(10)6-3-5(1-2-8-6)4-14(11,12)13/h5-6,8H,1-4H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 310: 563-70 (2004) Article DOI: 10.1124/jpet.104.066092 BindingDB Entry DOI: 10.7270/Q2DJ5D6D
					More data for this Ligand-Target Pair