Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric oxide synthase, inducible (Mus musculus (mouse)) | BDBM7886![]() (1-PIM | 1-phenyl-1H-imidazole | 1-phenylimidazole ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of inducible Nitric oxide synthase in activated murine macrophages. | Bioorg Med Chem Lett 5: 1825-1828 (1995) Article DOI: 10.1016/0960-894X(95)00317-M BindingDB Entry DOI: 10.7270/Q2057FVK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Mus musculus (mouse)) | BDBM50284964![]() (6-NITROINDAZOLE | 6-Nitro-1H-indazole | CHEMBL5427...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of inducible Nitric oxide synthase in activated murine macrophages. | Bioorg Med Chem Lett 5: 1825-1828 (1995) Article DOI: 10.1016/0960-894X(95)00317-M BindingDB Entry DOI: 10.7270/Q2057FVK | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Nitric oxide synthase, inducible (Mus musculus (mouse)) | BDBM50284963![]() (8,9-Dihydro-3H-naphtho[1,2-e][1,2,4]triazin-2-one ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of inducible Nitric oxide synthase in activated murine macrophages. | Bioorg Med Chem Lett 5: 1825-1828 (1995) Article DOI: 10.1016/0960-894X(95)00317-M BindingDB Entry DOI: 10.7270/Q2057FVK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM50321033![]() (CHEMBL1165508 | ent-17-Hydroxytrachyloban-18-oic a...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche de Gif Curated by ChEMBL | Assay Description Displacement of fluorescently-tagged BH3 peptide from Bcl-XL by fluorimetric assay | J Nat Prod 73: 1121-5 (2010) Article DOI: 10.1021/np100145n BindingDB Entry DOI: 10.7270/Q2CJ8DN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM50321034![]() (CHEMBL1165054 | ent-16alpha-Hydroxykaur-11-en-18-o...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche de Gif Curated by ChEMBL | Assay Description Displacement of fluorescently-tagged BH3 peptide from Bcl-XL by fluorimetric assay | J Nat Prod 73: 1121-5 (2010) Article DOI: 10.1021/np100145n BindingDB Entry DOI: 10.7270/Q2CJ8DN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM50321035![]() (CHEMBL1164460 | ent-Trachyloban-18-oic acid) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche de Gif Curated by ChEMBL | Assay Description Displacement of fluorescently-tagged BH3 peptide from Bcl-XL by fluorimetric assay | J Nat Prod 73: 1121-5 (2010) Article DOI: 10.1021/np100145n BindingDB Entry DOI: 10.7270/Q2CJ8DN2 | |||||||||||
More data for this Ligand-Target Pair |