Compile Data Set for Download or QSAR

Found 42 hits with Last Name = 'ruschel' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM163433 (BA-1049 | US11198680, Compound BA 1049 (R) | US968...) Show SMILES C[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI InChI=1S/C16H21N3O2S/c1-12(17)13-6-9-19(10-7-13)22(20,21)16-4-2-3-14-11-18-8-5-15(14)16/h2-5,8,11-13H,6-7,9-10,17H2,1H3/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM163433 (BA-1049 | US11198680, Compound BA 1049 (R) | US968...) Show SMILES C[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI InChI=1S/C16H21N3O2S/c1-12(17)13-6-9-19(10-7-13)22(20,21)16-4-2-3-14-11-18-8-5-15(14)16/h2-5,8,11-13H,6-7,9-10,17H2,1H3/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 15 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM163433 (BA-1049 | US11198680, Compound BA 1049 (R) | US968...) Show SMILES C[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI InChI=1S/C16H21N3O2S/c1-12(17)13-6-9-19(10-7-13)22(20,21)16-4-2-3-14-11-18-8-5-15(14)16/h2-5,8,11-13H,6-7,9-10,17H2,1H3/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 15 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM528675 (US11198680, Compound BA 1049B) Show SMILES C[C@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r,@@:3| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM528673 (US11198680, Compound Racemic-BA-1049-Lot-2) Show SMILES CC(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM528675 (US11198680, Compound BA 1049B) Show SMILES C[C@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r,@@:3| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM528674 (US11198680, Compound BA 1049A) Show SMILES C[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r,@:3| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM528670 (US11198680, Compound BA 1049 (S)) Show SMILES C[C@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM528670 (US11198680, Compound BA 1049 (S)) Show SMILES C[C@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 15 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM528670 (US11198680, Compound BA 1049 (S)) Show SMILES C[C@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 15 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM528673 (US11198680, Compound Racemic-BA-1049-Lot-2) Show SMILES CC(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM528673 (US11198680, Compound Racemic-BA-1049-Lot-2) Show SMILES CC(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM528673 (US11198680, Compound Racemic-BA-1049-Lot-2) Show SMILES CC(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM528674 (US11198680, Compound BA 1049A) Show SMILES C[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r,@:3| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM163433 (BA-1049 | US11198680, Compound BA 1049 (R) | US968...) Show SMILES C[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI InChI=1S/C16H21N3O2S/c1-12(17)13-6-9-19(10-7-13)22(20,21)16-4-2-3-14-11-18-8-5-15(14)16/h2-5,8,11-13H,6-7,9-10,17H2,1H3/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM528670 (US11198680, Compound BA 1049 (S)) Show SMILES C[C@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM163433 (BA-1049 | US11198680, Compound BA 1049 (R) | US968...) Show SMILES C[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI InChI=1S/C16H21N3O2S/c1-12(17)13-6-9-19(10-7-13)22(20,21)16-4-2-3-14-11-18-8-5-15(14)16/h2-5,8,11-13H,6-7,9-10,17H2,1H3/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	2.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 70 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM163433 (BA-1049 | US11198680, Compound BA 1049 (R) | US968...) Show SMILES C[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI InChI=1S/C16H21N3O2S/c1-12(17)13-6-9-19(10-7-13)22(20,21)16-4-2-3-14-11-18-8-5-15(14)16/h2-5,8,11-13H,6-7,9-10,17H2,1H3/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	2.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 70 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM528670 (US11198680, Compound BA 1049 (S)) Show SMILES C[C@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 70 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM528670 (US11198680, Compound BA 1049 (S)) Show SMILES C[C@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 70 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM528673 (US11198680, Compound Racemic-BA-1049-Lot-2) Show SMILES CC(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM163433 (BA-1049 | US11198680, Compound BA 1049 (R) | US968...) Show SMILES C[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI InChI=1S/C16H21N3O2S/c1-12(17)13-6-9-19(10-7-13)22(20,21)16-4-2-3-14-11-18-8-5-15(14)16/h2-5,8,11-13H,6-7,9-10,17H2,1H3/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM163433 (BA-1049 | US11198680, Compound BA 1049 (R) | US968...) Show SMILES C[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI InChI=1S/C16H21N3O2S/c1-12(17)13-6-9-19(10-7-13)22(20,21)16-4-2-3-14-11-18-8-5-15(14)16/h2-5,8,11-13H,6-7,9-10,17H2,1H3/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM528673 (US11198680, Compound Racemic-BA-1049-Lot-2) Show SMILES CC(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM528673 (US11198680, Compound Racemic-BA-1049-Lot-2) Show SMILES CC(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM529431 (US11198680, Compound BS-1043) Show SMILES CN(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM529431 (US11198680, Compound BS-1043) Show SMILES CN(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM529430 (US11198680, Compound BS-1042) Show SMILES CCCN(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM529430 (US11198680, Compound BS-1042) Show SMILES CCCN(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM529429 (US11198680, Compound BS-1041) Show SMILES CCCCCCCCCN(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM529429 (US11198680, Compound BS-1041) Show SMILES CCCCCCCCCN(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM322155 (US10183931, SLx-2119 | US10696660, SLx-2119 | US11...) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2ccccc2n1 Show InChI InChI=1S/C26H24N6O2/c1-16(2)28-24(33)15-34-20-7-5-6-17(13-20)25-30-23-9-4-3-8-21(23)26(31-25)29-19-10-11-22-18(12-19)14-27-32-22/h3-14,16H,15H2,1-2H3,(H,27,32)(H,28,33)(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM322155 (US10183931, SLx-2119 | US10696660, SLx-2119 | US11...) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2ccccc2n1 Show InChI InChI=1S/C26H24N6O2/c1-16(2)28-24(33)15-34-20-7-5-6-17(13-20)25-30-23-9-4-3-8-21(23)26(31-25)29-19-10-11-22-18(12-19)14-27-32-22/h3-14,16H,15H2,1-2H3,(H,27,32)(H,28,33)(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM14027 (5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...) Show SMILES O=S(=O)(N1CCCNCC1)c1cccc2cnccc12 Show InChI InChI=1S/C14H17N3O2S/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14/h1,3-5,7,11,15H,2,6,8-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair				3D Structure (crystal)
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM14027 (5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...) Show SMILES O=S(=O)(N1CCCNCC1)c1cccc2cnccc12 Show InChI InChI=1S/C14H17N3O2S/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14/h1,3-5,7,11,15H,2,6,8-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB US Patent	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair				3D Structure (crystal)
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM529434 (US11198680, Compound BS-1050B) Show SMILES CCC[C@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM529434 (US11198680, Compound BS-1050B) Show SMILES CCC[C@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM529433 (US11198680, Compound BS-1050A) Show SMILES CCC[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM529433 (US11198680, Compound BS-1050A) Show SMILES CCC[C@@H](N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM529432 (US11198680, Compound BS-1050) Show SMILES CCCC(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM528673 (US11198680, Compound Racemic-BA-1049-Lot-2) Show SMILES CC(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM529432 (US11198680, Compound BS-1050) Show SMILES CCCC(N)C1CCN(CC1)S(=O)(=O)c1cccc2cnccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
					More data for this Ligand-Target Pair