Found 1471 hits with Last Name = 'stanton' and Initial = 'j' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475698
(CHEMBL206748)Show InChI InChI=1S/C22H33NO2S/c24-26(25,21-10-2-1-3-11-21)22(13-6-14-22)15-7-16-23-17-12-19-8-4-5-9-20(19)18-23/h1-3,10-11,19-20H,4-9,12-18H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475694
(CHEMBL204269)Show SMILES CC(C)(CCCN1CCCC(C1)c1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H31NO2S/c1-23(2,27(25,26)22-14-7-4-8-15-22)16-10-18-24-17-9-13-21(19-24)20-11-5-3-6-12-20/h3-8,11-12,14-15,21H,9-10,13,16-19H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50357995
(CHEMBL202780)Show SMILES CC(C)(CCCN1CC[C@@H]2CCCC[C@H]2C1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H33NO2S/c1-21(2,25(23,24)20-11-4-3-5-12-20)14-8-15-22-16-13-18-9-6-7-10-19(18)17-22/h3-5,11-12,18-19H,6-10,13-17H2,1-2H3/t18-,19-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50297894
(2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...)Show InChI InChI=1S/C22H27NO2S/c24-26(25,21-10-2-1-3-11-21)22(13-6-14-22)15-7-16-23-17-12-19-8-4-5-9-20(19)18-23/h1-5,8-11H,6-7,12-18H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475691
(CHEMBL206563)Show SMILES O=S(=O)(c1ccccc1)C1(CCCN2CCC(C2)c2ccccc2)CCC1 Show InChI InChI=1S/C23H29NO2S/c25-27(26,22-11-5-2-6-12-22)23(14-7-15-23)16-8-17-24-18-13-21(19-24)20-9-3-1-4-10-20/h1-6,9-12,21H,7-8,13-19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475700
(CHEMBL206305)Show SMILES O=S(=O)(c1ccccc1)C1(CCCCN2CCC(C2)c2ccccc2)CCC1 Show InChI InChI=1S/C24H31NO2S/c26-28(27,23-12-5-2-6-13-23)24(16-9-17-24)15-7-8-18-25-19-14-22(20-25)21-10-3-1-4-11-21/h1-6,10-13,22H,7-9,14-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475692
(CHEMBL379238)Show SMILES CC(C)(CCCN1CCCC(C1)c1cnco1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H28N2O3S/c1-20(2,26(23,24)18-9-4-3-5-10-18)11-7-13-22-12-6-8-17(15-22)19-14-21-16-25-19/h3-5,9-10,14,16-17H,6-8,11-13,15H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475705
(CHEMBL206747)Show SMILES O=S(=O)(c1ccccc1)C1(CCCN2CCN(CC2)c2ccccc2)CCC1 Show InChI InChI=1S/C23H30N2O2S/c26-28(27,22-11-5-2-6-12-22)23(13-7-14-23)15-8-16-24-17-19-25(20-18-24)21-9-3-1-4-10-21/h1-6,9-12H,7-8,13-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475693
(CHEMBL203400)Show SMILES CCOC(=O)[C@@H]1CCCN(CCCC(C)(C)S(=O)(=O)c2ccccc2)C1 Show InChI InChI=1S/C20H31NO4S/c1-4-25-19(22)17-10-8-14-21(16-17)15-9-13-20(2,3)26(23,24)18-11-6-5-7-12-18/h5-7,11-12,17H,4,8-10,13-16H2,1-3H3/t17-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475699
(CHEMBL380613)Show SMILES O=S(=O)(c1ccccc1)C1(CCCN2CCC(CC2)c2ccccc2)CCC1 Show InChI InChI=1S/C24H31NO2S/c26-28(27,23-11-5-2-6-12-23)24(15-7-16-24)17-8-18-25-19-13-22(14-20-25)21-9-3-1-4-10-21/h1-6,9-12,22H,7-8,13-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50297894
(2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...)Show InChI InChI=1S/C22H27NO2S/c24-26(25,21-10-2-1-3-11-21)22(13-6-14-22)15-7-16-23-17-12-19-8-4-5-9-20(19)18-23/h1-5,8-11H,6-7,12-18H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT1A receptor expressed in HeLa cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475703
(CHEMBL382163)Show SMILES O=S(=O)(c1ccccc1)C1(CCN2CCC(C2)c2ccccc2)CCC1 Show InChI InChI=1S/C22H27NO2S/c24-26(25,21-10-5-2-6-11-21)22(13-7-14-22)15-17-23-16-12-20(18-23)19-8-3-1-4-9-19/h1-6,8-11,20H,7,12-18H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475695
(CHEMBL380511)Show SMILES CC(C)(CCCN1CCCC(C1)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H26F3NO2S/c1-17(2,25(23,24)16-9-4-3-5-10-16)11-7-13-22-12-6-8-15(14-22)18(19,20)21/h3-5,9-10,15H,6-8,11-14H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50297894
(2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...)Show InChI InChI=1S/C22H27NO2S/c24-26(25,21-10-2-1-3-11-21)22(13-6-14-22)15-7-16-23-17-12-19-8-4-5-9-20(19)18-23/h1-5,8-11H,6-7,12-18H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from the cloned human 5-HT2A receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475696
(CHEMBL206667)Show InChI InChI=1S/C19H29NO2S/c21-23(22,19-10-2-1-3-11-19)15-7-6-13-20-14-12-17-8-4-5-9-18(17)16-20/h1-3,10-11,17-18H,4-9,12-16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 96 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50475698
(CHEMBL206748)Show InChI InChI=1S/C22H33NO2S/c24-26(25,21-10-2-1-3-11-21)22(13-6-14-22)15-7-16-23-17-12-19-8-4-5-9-20(19)18-23/h1-3,10-11,19-20H,4-9,12-18H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT1A receptor expressed in HeLa cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50475694
(CHEMBL204269)Show SMILES CC(C)(CCCN1CCCC(C1)c1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H31NO2S/c1-23(2,27(25,26)22-14-7-4-8-15-22)16-10-18-24-17-9-13-21(19-24)20-11-5-3-6-12-20/h3-8,11-12,14-15,21H,9-10,13,16-19H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]spiperone from the cloned human D2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50475694
(CHEMBL204269)Show SMILES CC(C)(CCCN1CCCC(C1)c1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H31NO2S/c1-23(2,27(25,26)22-14-7-4-8-15-22)16-10-18-24-17-9-13-21(19-24)20-11-5-3-6-12-20/h3-8,11-12,14-15,21H,9-10,13,16-19H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT1A receptor expressed in HeLa cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475701
(CHEMBL204174)Show SMILES CCOC(=O)[C@H]1CCCN(CCCC(C)(C)S(=O)(=O)c2ccccc2)C1 Show InChI InChI=1S/C20H31NO4S/c1-4-25-19(22)17-10-8-14-21(16-17)15-9-13-20(2,3)26(23,24)18-11-6-5-7-12-18/h5-7,11-12,17H,4,8-10,13-16H2,1-3H3/t17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 455 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50475694
(CHEMBL204269)Show SMILES CC(C)(CCCN1CCCC(C1)c1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H31NO2S/c1-23(2,27(25,26)22-14-7-4-8-15-22)16-10-18-24-17-9-13-21(19-24)20-11-5-3-6-12-20/h3-8,11-12,14-15,21H,9-10,13,16-19H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha-1 adrenergic receptor in rat cortex |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475707
(CHEMBL206269)Show InChI InChI=1S/C19H29NO2S/c1-17-9-15-20(16-10-17)14-6-13-19(11-5-12-19)23(21,22)18-7-3-2-4-8-18/h2-4,7-8,17H,5-6,9-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50475698
(CHEMBL206748)Show InChI InChI=1S/C22H33NO2S/c24-26(25,21-10-2-1-3-11-21)22(13-6-14-22)15-7-16-23-17-12-19-8-4-5-9-20(19)18-23/h1-3,10-11,19-20H,4-9,12-18H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 570 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from the cloned human 5-HT2A receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50475693
(CHEMBL203400)Show SMILES CCOC(=O)[C@@H]1CCCN(CCCC(C)(C)S(=O)(=O)c2ccccc2)C1 Show InChI InChI=1S/C20H31NO4S/c1-4-25-19(22)17-10-8-14-21(16-17)15-9-13-20(2,3)26(23,24)18-11-6-5-7-12-18/h5-7,11-12,17H,4,8-10,13-16H2,1-3H3/t17-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]spiperone from the cloned human D2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50357995
(CHEMBL202780)Show SMILES CC(C)(CCCN1CC[C@@H]2CCCC[C@H]2C1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H33NO2S/c1-21(2,25(23,24)20-11-4-3-5-12-20)14-8-15-22-16-13-18-9-6-7-10-19(18)17-22/h3-5,11-12,18-19H,6-10,13-17H2,1-2H3/t18-,19-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]spiperone from the cloned human D2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50475695
(CHEMBL380511)Show SMILES CC(C)(CCCN1CCCC(C1)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H26F3NO2S/c1-17(2,25(23,24)16-9-4-3-5-10-16)11-7-13-22-12-6-8-15(14-22)18(19,20)21/h3-5,9-10,15H,6-8,11-14H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]spiperone from the cloned human D2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50475692
(CHEMBL379238)Show SMILES CC(C)(CCCN1CCCC(C1)c1cnco1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H28N2O3S/c1-20(2,26(23,24)18-9-4-3-5-10-18)11-7-13-22-12-6-8-17(15-22)19-14-21-16-25-19/h3-5,9-10,14,16-17H,6-8,11-13,15H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from the cloned human 5-HT2A receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50357995
(CHEMBL202780)Show SMILES CC(C)(CCCN1CC[C@@H]2CCCC[C@H]2C1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H33NO2S/c1-21(2,25(23,24)20-11-4-3-5-12-20)14-8-15-22-16-13-18-9-6-7-10-19(18)17-22/h3-5,11-12,18-19H,6-10,13-17H2,1-2H3/t18-,19-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT1A receptor expressed in HeLa cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50475692
(CHEMBL379238)Show SMILES CC(C)(CCCN1CCCC(C1)c1cnco1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H28N2O3S/c1-20(2,26(23,24)18-9-4-3-5-10-18)11-7-13-22-12-6-8-17(15-22)19-14-21-16-25-19/h3-5,9-10,14,16-17H,6-8,11-13,15H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]spiperone from the cloned human D2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50475694
(CHEMBL204269)Show SMILES CC(C)(CCCN1CCCC(C1)c1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H31NO2S/c1-23(2,27(25,26)22-14-7-4-8-15-22)16-10-18-24-17-9-13-21(19-24)20-11-5-3-6-12-20/h3-8,11-12,14-15,21H,9-10,13,16-19H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from the cloned human 5-HT2A receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50475693
(CHEMBL203400)Show SMILES CCOC(=O)[C@@H]1CCCN(CCCC(C)(C)S(=O)(=O)c2ccccc2)C1 Show InChI InChI=1S/C20H31NO4S/c1-4-25-19(22)17-10-8-14-21(16-17)15-9-13-20(2,3)26(23,24)18-11-6-5-7-12-18/h5-7,11-12,17H,4,8-10,13-16H2,1-3H3/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from the cloned human 5-HT2A receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50357995
(CHEMBL202780)Show SMILES CC(C)(CCCN1CC[C@@H]2CCCC[C@H]2C1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H33NO2S/c1-21(2,25(23,24)20-11-4-3-5-12-20)14-8-15-22-16-13-18-9-6-7-10-19(18)17-22/h3-5,11-12,18-19H,6-10,13-17H2,1-2H3/t18-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from the cloned human 5-HT2A receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50475695
(CHEMBL380511)Show SMILES CC(C)(CCCN1CCCC(C1)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H26F3NO2S/c1-17(2,25(23,24)16-9-4-3-5-10-16)11-7-13-22-12-6-8-15(14-22)18(19,20)21/h3-5,9-10,15H,6-8,11-14H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from the cloned human 5-HT2A receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50475693
(CHEMBL203400)Show SMILES CCOC(=O)[C@@H]1CCCN(CCCC(C)(C)S(=O)(=O)c2ccccc2)C1 Show InChI InChI=1S/C20H31NO4S/c1-4-25-19(22)17-10-8-14-21(16-17)15-9-13-20(2,3)26(23,24)18-11-6-5-7-12-18/h5-7,11-12,17H,4,8-10,13-16H2,1-3H3/t17-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT1A receptor expressed in HeLa cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475702
(CHEMBL380863)Show InChI InChI=1S/C18H27NO2S/c20-22(21,17-9-3-1-4-10-17)18(11-7-12-18)13-8-16-19-14-5-2-6-15-19/h1,3-4,9-10H,2,5-8,11-16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50357995
(CHEMBL202780)Show SMILES CC(C)(CCCN1CC[C@@H]2CCCC[C@H]2C1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H33NO2S/c1-21(2,25(23,24)20-11-4-3-5-12-20)14-8-15-22-16-13-18-9-6-7-10-19(18)17-22/h3-5,11-12,18-19H,6-10,13-17H2,1-2H3/t18-,19-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha-1 adrenergic receptor in rat cortex |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50475695
(CHEMBL380511)Show SMILES CC(C)(CCCN1CCCC(C1)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H26F3NO2S/c1-17(2,25(23,24)16-9-4-3-5-10-16)11-7-13-22-12-6-8-15(14-22)18(19,20)21/h3-5,9-10,15H,6-8,11-14H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha-1 adrenergic receptor in rat cortex |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50357995
(CHEMBL202780)Show SMILES CC(C)(CCCN1CC[C@@H]2CCCC[C@H]2C1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H33NO2S/c1-21(2,25(23,24)20-11-4-3-5-12-20)14-8-15-22-16-13-18-9-6-7-10-19(18)17-22/h3-5,11-12,18-19H,6-10,13-17H2,1-2H3/t18-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [35S]-labeled MK-499 from cloned human ERG receptor expressed in HEK cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50475692
(CHEMBL379238)Show SMILES CC(C)(CCCN1CCCC(C1)c1cnco1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H28N2O3S/c1-20(2,26(23,24)18-9-4-3-5-10-18)11-7-13-22-12-6-8-17(15-22)19-14-21-16-25-19/h3-5,9-10,14,16-17H,6-8,11-13,15H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha-1 adrenergic receptor in rat cortex |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50475693
(CHEMBL203400)Show SMILES CCOC(=O)[C@@H]1CCCN(CCCC(C)(C)S(=O)(=O)c2ccccc2)C1 Show InChI InChI=1S/C20H31NO4S/c1-4-25-19(22)17-10-8-14-21(16-17)15-9-13-20(2,3)26(23,24)18-11-6-5-7-12-18/h5-7,11-12,17H,4,8-10,13-16H2,1-3H3/t17-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]prazosin from alpha-1 adrenergic receptor in rat cortex |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50475693
(CHEMBL203400)Show SMILES CCOC(=O)[C@@H]1CCCN(CCCC(C)(C)S(=O)(=O)c2ccccc2)C1 Show InChI InChI=1S/C20H31NO4S/c1-4-25-19(22)17-10-8-14-21(16-17)15-9-13-20(2,3)26(23,24)18-11-6-5-7-12-18/h5-7,11-12,17H,4,8-10,13-16H2,1-3H3/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [35S]-labeled MK-499 from cloned human ERG receptor expressed in HEK cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50475695
(CHEMBL380511)Show SMILES CC(C)(CCCN1CCCC(C1)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H26F3NO2S/c1-17(2,25(23,24)16-9-4-3-5-10-16)11-7-13-22-12-6-8-15(14-22)18(19,20)21/h3-5,9-10,15H,6-8,11-14H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [35S]-labeled MK-499 from cloned human ERG receptor expressed in HEK cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50475694
(CHEMBL204269)Show SMILES CC(C)(CCCN1CCCC(C1)c1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H31NO2S/c1-23(2,27(25,26)22-14-7-4-8-15-22)16-10-18-24-17-9-13-21(19-24)20-11-5-3-6-12-20/h3-8,11-12,14-15,21H,9-10,13,16-19H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [35S]-labeled MK-499 from cloned human ERG receptor expressed in HEK cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50475692
(CHEMBL379238)Show SMILES CC(C)(CCCN1CCCC(C1)c1cnco1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H28N2O3S/c1-20(2,26(23,24)18-9-4-3-5-10-18)11-7-13-22-12-6-8-17(15-22)19-14-21-16-25-19/h3-5,9-10,14,16-17H,6-8,11-13,15H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT1B receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475706
(CHEMBL425767)Show InChI InChI=1S/C18H28N2O2S/c1-19-13-15-20(16-14-19)12-6-11-18(9-5-10-18)23(21,22)17-7-3-2-4-8-17/h2-4,7-8H,5-6,9-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50475693
(CHEMBL203400)Show SMILES CCOC(=O)[C@@H]1CCCN(CCCC(C)(C)S(=O)(=O)c2ccccc2)C1 Show InChI InChI=1S/C20H31NO4S/c1-4-25-19(22)17-10-8-14-21(16-17)15-9-13-20(2,3)26(23,24)18-11-6-5-7-12-18/h5-7,11-12,17H,4,8-10,13-16H2,1-3H3/t17-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT1B receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475697
(CHEMBL380114)Show InChI InChI=1S/C15H23NO2S/c1-16(2)13-7-12-15(10-6-11-15)19(17,18)14-8-4-3-5-9-14/h3-5,8-9H,6-7,10-13H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50357995
(CHEMBL202780)Show SMILES CC(C)(CCCN1CC[C@@H]2CCCC[C@H]2C1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H33NO2S/c1-21(2,25(23,24)20-11-4-3-5-12-20)14-8-15-22-16-13-18-9-6-7-10-19(18)17-22/h3-5,11-12,18-19H,6-10,13-17H2,1-2H3/t18-,19-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| >7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT1B receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50475695
(CHEMBL380511)Show SMILES CC(C)(CCCN1CCCC(C1)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H26F3NO2S/c1-17(2,25(23,24)16-9-4-3-5-10-16)11-7-13-22-12-6-8-15(14-22)18(19,20)21/h3-5,9-10,15H,6-8,11-14H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT1B receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50475704
(CHEMBL383232)Show InChI InChI=1S/C17H25NO3S/c19-22(20,16-6-2-1-3-7-16)17(8-4-9-17)10-5-11-18-12-14-21-15-13-18/h1-3,6-7H,4-5,8-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50475695
(CHEMBL380511)Show SMILES CC(C)(CCCN1CCCC(C1)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H26F3NO2S/c1-17(2,25(23,24)16-9-4-3-5-10-16)11-7-13-22-12-6-8-15(14-22)18(19,20)21/h3-5,9-10,15H,6-8,11-14H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]5-HT from the cloned human 5-HT1A receptor expressed in HeLa cells |
Bioorg Med Chem Lett 16: 1255-8 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.067 BindingDB Entry DOI: 10.7270/Q28D001P |
More data for this Ligand-Target Pair | |