Compile Data Set for Download or QSAR

Found 719 hits with Last Name = 'picard' and Initial = 'ja'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50084286 (2-(4'-Cyano-biphenyl-4-sulfonylamino)-N-hydroxy-3-...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)C#N)C(=O)NO Show InChI InChI=1S/C18H19N3O4S/c1-12(2)17(18(22)20-23)21-26(24,25)16-9-7-15(8-10-16)14-5-3-13(11-19)4-6-14/h3-10,12,17,21,23H,1-2H3,(H,20,22)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50084286 (2-(4'-Cyano-biphenyl-4-sulfonylamino)-N-hydroxy-3-...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)C#N)C(=O)NO Show InChI InChI=1S/C18H19N3O4S/c1-12(2)17(18(22)20-23)21-26(24,25)16-9-7-15(8-10-16)14-5-3-13(11-19)4-6-14/h3-10,12,17,21,23H,1-2H3,(H,20,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM8485 ((2R)-N-hydroxy-3-methyl-2-[(4-phenoxybenzene)sulfo...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C17H20N2O5S/c1-12(2)16(17(20)18-21)19-25(22,23)15-10-8-14(9-11-15)24-13-6-4-3-5-7-13/h3-12,16,19,21H,1-2H3,(H,18,20)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM12076 ((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-N-h...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(=O)NO |r| Show InChI InChI=1S/C17H19BrN2O4S/c1-11(2)16(17(21)19-22)20-25(23,24)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,20,22H,1-2H3,(H,19,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50084291 (2-(4'-Bromo-biphenyl-4-sulfonylamino)-4-phenylmeth...) Show SMILES OC(=O)C(CCS(=O)(=O)Cc1ccccc1)NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1 Show InChI InChI=1S/C23H22BrNO6S2/c24-20-10-6-18(7-11-20)19-8-12-21(13-9-19)33(30,31)25-22(23(26)27)14-15-32(28,29)16-17-4-2-1-3-5-17/h1-13,22,25H,14-16H2,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM12076 ((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-N-h...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(=O)NO |r| Show InChI InChI=1S/C17H19BrN2O4S/c1-11(2)16(17(21)19-22)20-25(23,24)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,20,22H,1-2H3,(H,19,21)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50084283 ((S)-3-methyl-2-(4'-methyl-biphenyl-4-sulfonylamino...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(C)cc1)C(O)=O Show InChI InChI=1S/C18H21NO4S/c1-12(2)17(18(20)21)19-24(22,23)16-10-8-15(9-11-16)14-6-4-13(3)5-7-14/h4-12,17,19H,1-3H3,(H,20,21)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50011204 (CHEMBL2368094 | Sodium; 7-[4-(4-fluoro-phenyl)-2-i...) Show SMILES [Na+].CC(C)c1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1 Show InChI InChI=1S/C27H28FNO4.Na/c1-17(2)27-23(13-12-21(30)14-22(31)15-26(32)33)24(18-8-10-20(28)11-9-18)16-25(29-27)19-6-4-3-5-7-19;/h3-13,16-17,21-22,30-31H,14-15H2,1-2H3,(H,32,33);/q;+1/p-1/b13-12+;/t21-,22-;/m1./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Ability to inhibit microsomal preparation of HMG-CoA reductase in rat liver.				J Med Chem 34: 463-6 (1991) BindingDB Entry DOI: 10.7270/Q2MS3TC4
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM8485 ((2R)-N-hydroxy-3-methyl-2-[(4-phenoxybenzene)sulfo...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C17H20N2O5S/c1-12(2)16(17(20)18-21)19-25(22,23)15-10-8-14(9-11-15)24-13-6-4-3-5-7-13/h3-12,16,19,21H,1-2H3,(H,18,20)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084283 ((S)-3-methyl-2-(4'-methyl-biphenyl-4-sulfonylamino...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(C)cc1)C(O)=O Show InChI InChI=1S/C18H21NO4S/c1-12(2)17(18(20)21)19-24(22,23)16-10-8-15(9-11-16)14-6-4-13(3)5-7-14/h4-12,17,19H,1-3H3,(H,20,21)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM8485 ((2R)-N-hydroxy-3-methyl-2-[(4-phenoxybenzene)sulfo...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C17H20N2O5S/c1-12(2)16(17(20)18-21)19-25(22,23)15-10-8-14(9-11-15)24-13-6-4-3-5-7-13/h3-12,16,19,21H,1-2H3,(H,18,20)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-9 (MMP-9)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50084289 ((S)-2-(4'-methoxy-biphenyl-4-sulfonylamino)-3-meth...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21NO5S/c1-12(2)17(18(20)21)19-25(22,23)16-10-6-14(7-11-16)13-4-8-15(24-3)9-5-13/h4-12,17,19H,1-3H3,(H,20,21)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50084297 (2-(4'-Bromo-biphenyl-4-sulfonylamino)-6-(3-phenyl-...) Show SMILES OC(=O)[C@H](CCCCNC(=O)CCc1ccccc1)NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1 Show InChI InChI=1S/C27H29BrN2O5S/c28-23-14-10-21(11-15-23)22-12-16-24(17-13-22)36(34,35)30-25(27(32)33)8-4-5-19-29-26(31)18-9-20-6-2-1-3-7-20/h1-3,6-7,10-17,25,30H,4-5,8-9,18-19H2,(H,29,31)(H,32,33)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50084297 (2-(4'-Bromo-biphenyl-4-sulfonylamino)-6-(3-phenyl-...) Show SMILES OC(=O)[C@H](CCCCNC(=O)CCc1ccccc1)NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1 Show InChI InChI=1S/C27H29BrN2O5S/c28-23-14-10-21(11-15-23)22-12-16-24(17-13-22)36(34,35)30-25(27(32)33)8-4-5-19-29-26(31)18-9-20-6-2-1-3-7-20/h1-3,6-7,10-17,25,30H,4-5,8-9,18-19H2,(H,29,31)(H,32,33)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM12075 ((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(O)=O |r| Show InChI InChI=1S/C17H18BrNO4S/c1-11(2)16(17(20)21)19-24(22,23)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,19H,1-2H3,(H,20,21)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50289025 (CHEMBL164479 | N-(2,6-Diisopropyl-phenyl)-malonami...) Show SMILES CCCCCCCCCCCC[C@H](C)OC(=O)CC(=O)Nc1c(cccc1C(C)C)C(C)C Show InChI InChI=1S/C29H49NO3/c1-7-8-9-10-11-12-13-14-15-16-18-24(6)33-28(32)21-27(31)30-29-25(22(2)3)19-17-20-26(29)23(4)5/h17,19-20,22-24H,7-16,18,21H2,1-6H3,(H,30,31)/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...				Bioorg Med Chem Lett 6: 713-718 (1996) Article DOI: 10.1016/0960-894X(96)00098-4 BindingDB Entry DOI: 10.7270/Q2DV1JV5
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50084304 ((4'-Bromo-biphenyl-4-sulfonylamino)-acetic acid | ...) Show SMILES OC(=O)CNS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1 Show InChI InChI=1S/C14H12BrNO4S/c15-12-5-1-10(2-6-12)11-3-7-13(8-4-11)21(19,20)16-9-14(17)18/h1-8,16H,9H2,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50289051 (CHEMBL160103 | N-(2,6-Diisopropyl-phenyl)-malonami...) Show SMILES CCCCCCCCCCCC[C@@H](C)OC(=O)CC(=O)Nc1c(cccc1C(C)C)C(C)C Show InChI InChI=1S/C29H49NO3/c1-7-8-9-10-11-12-13-14-15-16-18-24(6)33-28(32)21-27(31)30-29-25(22(2)3)19-17-20-26(29)23(4)5/h17,19-20,22-24H,7-16,18,21H2,1-6H3,(H,30,31)/t24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...				Bioorg Med Chem Lett 6: 713-718 (1996) Article DOI: 10.1016/0960-894X(96)00098-4 BindingDB Entry DOI: 10.7270/Q2DV1JV5
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM8485 ((2R)-N-hydroxy-3-methyl-2-[(4-phenoxybenzene)sulfo...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO |r| Show InChI InChI=1S/C17H20N2O5S/c1-12(2)16(17(20)18-21)19-25(22,23)15-10-8-14(9-11-15)24-13-6-4-3-5-7-13/h3-12,16,19,21H,1-2H3,(H,18,20)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50084281 (2-(4'-Bromo-biphenyl-4-sulfonylamino)-4-methyl-pen...) Show SMILES CC(C)C[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(O)=O Show InChI InChI=1S/C18H20BrNO4S/c1-12(2)11-17(18(21)22)20-25(23,24)16-9-5-14(6-10-16)13-3-7-15(19)8-4-13/h3-10,12,17,20H,11H2,1-2H3,(H,21,22)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084286 (2-(4'-Cyano-biphenyl-4-sulfonylamino)-N-hydroxy-3-...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)C#N)C(=O)NO Show InChI InChI=1S/C18H19N3O4S/c1-12(2)17(18(22)20-23)21-26(24,25)16-9-7-15(8-10-16)14-5-3-13(11-19)4-6-14/h3-10,12,17,21,23H,1-2H3,(H,20,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084295 (2-(4'-Cyano-biphenyl-4-sulfonylamino)-3-methyl-but...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)C#N)C(O)=O Show InChI InChI=1S/C18H18N2O4S/c1-12(2)17(18(21)22)20-25(23,24)16-9-7-15(8-10-16)14-5-3-13(11-19)4-6-14/h3-10,12,17,20H,1-2H3,(H,21,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50051461 (CHEMBL264861 | N-(2,6-Diisopropyl-phenyl)-2-(2-dod...) Show SMILES CCCCCCCCCCCCn1nnc(CC(=O)Nc2c(cccc2C(C)C)C(C)C)n1 Show InChI InChI=1S/C27H45N5O/c1-6-7-8-9-10-11-12-13-14-15-19-32-30-25(29-31-32)20-26(33)28-27-23(21(2)3)17-16-18-24(27)22(4)5/h16-18,21-22H,6-15,19-20H2,1-5H3,(H,28,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase 1 of liver microsomes isolated from cholesterol-fed rats.				J Med Chem 39: 2354-66 (1996) Article DOI: 10.1021/jm960170f BindingDB Entry DOI: 10.7270/Q2W66JVV
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50084290 ((S)-2-(4'-bromo-2'-fluoro-biphenyl-4-sulfonylamino...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1F)C(O)=O Show InChI InChI=1S/C17H17BrFNO4S/c1-10(2)16(17(21)22)20-25(23,24)13-6-3-11(4-7-13)14-8-5-12(18)9-15(14)19/h3-10,16,20H,1-2H3,(H,21,22)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM12076 ((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-N-h...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(=O)NO |r| Show InChI InChI=1S/C17H19BrN2O4S/c1-11(2)16(17(21)19-22)20-25(23,24)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,20,22H,1-2H3,(H,19,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM12074 ((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(O)=O |r| Show InChI InChI=1S/C17H18BrNO4S/c1-11(2)16(17(20)21)19-24(22,23)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,19H,1-2H3,(H,20,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084287 ((S)-2-(4'-cyano-biphenyl-4-sulfonylamino)-3-methyl...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)C#N)C(O)=O Show InChI InChI=1S/C18H18N2O4S/c1-12(2)17(18(21)22)20-25(23,24)16-9-7-15(8-10-16)14-5-3-13(11-19)4-6-14/h3-10,12,17,20H,1-2H3,(H,21,22)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50084289 ((S)-2-(4'-methoxy-biphenyl-4-sulfonylamino)-3-meth...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21NO5S/c1-12(2)17(18(20)21)19-25(22,23)16-10-6-14(7-11-16)13-4-8-15(24-3)9-5-13/h4-12,17,19H,1-3H3,(H,20,21)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50051466 (CHEMBL175982 | N-(2,6-Diisopropyl-phenyl)-2-(5-dod...) Show SMILES CCCCCCCCCCCCc1nnn(CC(=O)Nc2c(cccc2C(C)C)C(C)C)n1 Show InChI InChI=1S/C27H45N5O/c1-6-7-8-9-10-11-12-13-14-15-19-25-29-31-32(30-25)20-26(33)28-27-23(21(2)3)17-16-18-24(27)22(4)5/h16-18,21-22H,6-15,19-20H2,1-5H3,(H,28,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase 1 of liver microsomes isolated from cholesterol-fed rats.				J Med Chem 39: 2354-66 (1996) Article DOI: 10.1021/jm960170f BindingDB Entry DOI: 10.7270/Q2W66JVV
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50289024 (CHEMBL422709 | N-(2,6-Diisopropyl-phenyl)-malonami...) Show SMILES CCCCCCCCCCC(C)OC(=O)CC(=O)Nc1c(cccc1C(C)C)C(C)C Show InChI InChI=1S/C27H45NO3/c1-7-8-9-10-11-12-13-14-16-22(6)31-26(30)19-25(29)28-27-23(20(2)3)17-15-18-24(27)21(4)5/h15,17-18,20-22H,7-14,16,19H2,1-6H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI)...				Bioorg Med Chem Lett 6: 713-718 (1996) Article DOI: 10.1016/0960-894X(96)00098-4 BindingDB Entry DOI: 10.7270/Q2DV1JV5
					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50006407 (CHEMBL2367472 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...) Show SMILES [Na+].CC(C)c1nn(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)-c1cnccn1 Show InChI InChI=1S/C23H25FN4O4.Na/c1-14(2)22-19(8-7-17(29)11-18(30)12-21(31)32)23(15-3-5-16(24)6-4-15)28(27-22)20-13-25-9-10-26-20;/h3-10,13-14,17-18,29-30H,11-12H2,1-2H3,(H,31,32);/q;+1/p-1/b8-7+;/t17-,18-;/m1./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Ability to inhibit microsomal preparation of HMG-CoA reductase in rat liver.				J Med Chem 34: 463-6 (1991) BindingDB Entry DOI: 10.7270/Q2MS3TC4
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50084290 ((S)-2-(4'-bromo-2'-fluoro-biphenyl-4-sulfonylamino...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1F)C(O)=O Show InChI InChI=1S/C17H17BrFNO4S/c1-10(2)16(17(21)22)20-25(23,24)13-6-3-11(4-7-13)14-8-5-12(18)9-15(14)19/h3-10,16,20H,1-2H3,(H,21,22)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human))	BDBM50006407 (CHEMBL2367472 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...) Show SMILES [Na+].CC(C)c1nn(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)-c1cnccn1 Show InChI InChI=1S/C23H25FN4O4.Na/c1-14(2)22-19(8-7-17(29)11-18(30)12-21(31)32)23(15-3-5-16(24)6-4-15)28(27-22)20-13-25-9-10-26-20;/h3-10,13-14,17-18,29-30H,11-12H2,1-2H3,(H,31,32);/q;+1/p-1/b8-7+;/t17-,18-;/m1./s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.				J Med Chem 35: 2095-103 (1992) BindingDB Entry DOI: 10.7270/Q2HH6KN8
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084281 (2-(4'-Bromo-biphenyl-4-sulfonylamino)-4-methyl-pen...) Show SMILES CC(C)C[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(O)=O Show InChI InChI=1S/C18H20BrNO4S/c1-12(2)11-17(18(21)22)20-25(23,24)16-9-5-14(6-10-16)13-3-7-15(19)8-4-13/h3-10,12,17,20H,11H2,1-2H3,(H,21,22)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084291 (2-(4'-Bromo-biphenyl-4-sulfonylamino)-4-phenylmeth...) Show SMILES OC(=O)C(CCS(=O)(=O)Cc1ccccc1)NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1 Show InChI InChI=1S/C23H22BrNO6S2/c24-20-10-6-18(7-11-20)19-8-12-21(13-9-19)33(30,31)25-22(23(26)27)14-15-32(28,29)16-17-4-2-1-3-5-17/h1-13,22,25H,14-16H2,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human))	BDBM50006407 (CHEMBL2367472 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...) Show SMILES [Na+].CC(C)c1nn(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)-c1cnccn1 Show InChI InChI=1S/C23H25FN4O4.Na/c1-14(2)22-19(8-7-17(29)11-18(30)12-21(31)32)23(15-3-5-16(24)6-4-15)28(27-22)20-13-25-9-10-26-20;/h3-10,13-14,17-18,29-30H,11-12H2,1-2H3,(H,31,32);/q;+1/p-1/b8-7+;/t17-,18-;/m1./s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.				J Med Chem 35: 2095-103 (1992) BindingDB Entry DOI: 10.7270/Q2HH6KN8
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM12075 ((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(O)=O |r| Show InChI InChI=1S/C17H18BrNO4S/c1-11(2)16(17(20)21)19-24(22,23)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,19H,1-2H3,(H,20,21)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50069883 ((2,6-Diisopropyl-phenylcarbamoyl)-methanesulfonic ...) Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)CS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C Show InChI InChI=1S/C26H37NO4S/c1-16(2)20-11-9-12-21(17(3)4)25(20)27-24(28)15-32(29,30)31-26-22(18(5)6)13-10-14-23(26)19(7)8/h9-14,16-19H,15H2,1-8H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro inhibition of ACAT by incubation with [1-14C]-oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.				Bioorg Med Chem Lett 8: 289-94 (1999) BindingDB Entry DOI: 10.7270/Q2DN446R
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50069886 ((2,6-Diisopropyl-phenylcarbamoyl)-methanesulfonic ...) Show SMILES CC(C)c1cc(C(C)C)c(OS(=O)(=O)CC(=O)Nc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C Show InChI InChI=1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)29(26(15-22)21(9)10)34-35(32,33)16-27(31)30-28-23(18(3)4)12-11-13-24(28)19(5)6/h11-15,17-21H,16H2,1-10H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro inhibition of ACAT by incubation with [1-14C]-oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.				Bioorg Med Chem Lett 8: 289-94 (1999) BindingDB Entry DOI: 10.7270/Q2DN446R
					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human))	BDBM50006409 (CHEMBL2367478 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...) Show SMILES [Na+].CC(C)c1nn(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)-c1ccccc1 Show InChI InChI=1S/C25H27FN2O4.Na/c1-16(2)24-22(13-12-20(29)14-21(30)15-23(31)32)25(17-8-10-18(26)11-9-17)28(27-24)19-6-4-3-5-7-19;/h3-13,16,20-21,29-30H,14-15H2,1-2H3,(H,31,32);/q;+1/p-1/b13-12+;/t20-,21-;/m1./s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.				J Med Chem 35: 2095-103 (1992) BindingDB Entry DOI: 10.7270/Q2HH6KN8
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50084295 (2-(4'-Cyano-biphenyl-4-sulfonylamino)-3-methyl-but...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)C#N)C(O)=O Show InChI InChI=1S/C18H18N2O4S/c1-12(2)17(18(21)22)20-25(23,24)16-9-7-15(8-10-16)14-5-3-13(11-19)4-6-14/h3-10,12,17,20H,1-2H3,(H,21,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50084298 (4-Benzylsulfanyl-2-(4'-bromo-biphenyl-4-sulfonylam...) Show SMILES OC(=O)C(CCSCc1ccccc1)NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1 Show InChI InChI=1S/C23H22BrNO4S2/c24-20-10-6-18(7-11-20)19-8-12-21(13-9-19)31(28,29)25-22(23(26)27)14-15-30-16-17-4-2-1-3-5-17/h1-13,22,25H,14-16H2,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of matrix metalloprotease-2 (MMP-2)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50084300 (2-(4'-Bromo-biphenyl-4-sulfonylamino)-5-(3-phenyl-...) Show SMILES OC(=O)[C@H](CCCNC(=O)CCc1ccccc1)NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1 Show InChI InChI=1S/C26H27BrN2O5S/c27-22-13-9-20(10-14-22)21-11-15-23(16-12-21)35(33,34)29-24(26(31)32)7-4-18-28-25(30)17-8-19-5-2-1-3-6-19/h1-3,5-6,9-16,24,29H,4,7-8,17-18H2,(H,28,30)(H,31,32)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50006409 (CHEMBL2367478 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...) Show SMILES [Na+].CC(C)c1nn(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)-c1ccccc1 Show InChI InChI=1S/C25H27FN2O4.Na/c1-16(2)24-22(13-12-20(29)14-21(30)15-23(31)32)25(17-8-10-18(26)11-9-17)28(27-24)19-6-4-3-5-7-19;/h3-13,16,20-21,29-30H,14-15H2,1-2H3,(H,31,32);/q;+1/p-1/b13-12+;/t20-,21-;/m1./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Ability to inhibit microsomal preparation of HMG-CoA reductase in rat liver.				J Med Chem 34: 463-6 (1991) BindingDB Entry DOI: 10.7270/Q2MS3TC4
					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50011213 (CHEMBL3349878 | Sodium; 7-[2-(4-fluoro-phenyl)-5-i...) Show SMILES [Na+].CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1 Show InChI InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/p-1/t26?,27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Ability to inhibit microsomal preparation of HMG-CoA reductase in rat liver.				J Med Chem 34: 463-6 (1991) BindingDB Entry DOI: 10.7270/Q2MS3TC4
					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat))	BDBM50011211 (CHEMBL2368089 | Sodium; 7-[4-(4-fluoro-phenyl)-2-i...) Show SMILES [Na+].CC(C)c1nc(C)cc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O Show InChI InChI=1S/C22H26FNO4.Na/c1-13(2)22-19(9-8-17(25)11-18(26)12-21(27)28)20(10-14(3)24-22)15-4-6-16(23)7-5-15;/h4-10,13,17-18,25-26H,11-12H2,1-3H3,(H,27,28);/q;+1/p-1/b9-8+;/t17-,18-;/m1./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Ability to inhibit microsomal preparation of HMG-CoA reductase in rat liver.				J Med Chem 34: 463-6 (1991) BindingDB Entry DOI: 10.7270/Q2MS3TC4
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084302 ((S)-2-(4'-formyl-biphenyl-4-sulfonylamino)-3-methy...) Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(C=O)cc1)C(O)=O Show InChI InChI=1S/C18H19NO5S/c1-12(2)17(18(21)22)19-25(23,24)16-9-7-15(8-10-16)14-5-3-13(11-20)4-6-14/h3-12,17,19H,1-2H3,(H,21,22)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50063243 (CHEMBL161499 | N-(2,6-Diisopropyl-phenyl)-2-pyridi...) Show SMILES CCCCCCCCCCCCOC(=O)C(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccn1 Show InChI InChI=1S/C32H48N2O3/c1-6-7-8-9-10-11-12-13-14-17-23-37-32(36)29(28-21-15-16-22-33-28)31(35)34-30-26(24(2)3)19-18-20-27(30)25(4)5/h15-16,18-22,24-25,29H,6-14,17,23H2,1-5H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro Acyl coenzyme A:cholesterol acyltransferase inhibition in hepatic microsomes isolated from cholesterol-fed rats				J Med Chem 41: 682-90 (1998) Article DOI: 10.1021/jm970560h BindingDB Entry DOI: 10.7270/Q28051R8
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM12074 ((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...) Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(O)=O |r| Show InChI InChI=1S/C17H18BrNO4S/c1-11(2)16(17(20)21)19-24(22,23)15-9-5-13(6-10-15)12-3-7-14(18)8-4-12/h3-11,16,19H,1-2H3,(H,20,21)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 156-66 (2000) BindingDB Entry DOI: 10.7270/Q2T154BF
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50051460 (2-(2-Dodecyl-2H-tetrazol-5-yl)-2-phenyl-N-(2,4,6-t...) Show SMILES CCCCCCCCCCCCn1nnc(n1)C(C(=O)Nc1c(OC)cc(OC)cc1OC)c1ccccc1 Show InChI InChI=1S/C30H43N5O4/c1-5-6-7-8-9-10-11-12-13-17-20-35-33-29(32-34-35)27(23-18-15-14-16-19-23)30(36)31-28-25(38-3)21-24(37-2)22-26(28)39-4/h14-16,18-19,21-22,27H,5-13,17,20H2,1-4H3,(H,31,36)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against Acyl coenzyme A:cholesterol acyltransferase 1 from rabbit intestine				J Med Chem 39: 2354-66 (1996) Article DOI: 10.1021/jm960170f BindingDB Entry DOI: 10.7270/Q2W66JVV
					More data for this Ligand-Target Pair

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