Compile Data Set for Download or QSAR

Found 110 hits with Last Name = 'wurster' and Initial = 'ja'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM144589 (US8969583, 5) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCOCC3)c2C(N)=O)c1 Show InChI InChI=1S/C26H31N7O4S/c1-17-4-2-5-20(16-17)30-26(36)29-19-8-6-18(7-9-19)22-21(23(27)34)24(38-32-22)31-25(35)28-10-3-11-33-12-14-37-15-13-33/h2,4-9,16H,3,10-15H2,1H3,(H2,27,34)(H2,28,31,35)(H2,29,30,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144589 (US8969583, 5) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCOCC3)c2C(N)=O)c1 Show InChI InChI=1S/C26H31N7O4S/c1-17-4-2-5-20(16-17)30-26(36)29-19-8-6-18(7-9-19)22-21(23(27)34)24(38-32-22)31-25(35)28-10-3-11-33-12-14-37-15-13-33/h2,4-9,16H,3,10-15H2,1H3,(H2,27,34)(H2,28,31,35)(H2,29,30,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM214710 (US9296747, Example 5) Show SMILES COc1ccc(Nc2ncc3CN(CCc3n2)C(=O)c2cccnc2)cc1 Show InChI InChI=1S/C20H19N5O2/c1-27-17-6-4-16(5-7-17)23-20-22-12-15-13-25(10-8-18(15)24-20)19(26)14-3-2-9-21-11-14/h2-7,9,11-12H,8,10,13H2,1H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM214717 (US9296747, Example 12) Show SMILES COc1cc(Nc2ncc3CN(CCc3n2)C(=O)c2cc(C)nn2C)cc(OC)c1OC Show InChI InChI=1S/C22H26N6O4/c1-13-8-17(27(2)26-13)21(29)28-7-6-16-14(12-28)11-23-22(25-16)24-15-9-18(30-3)20(32-5)19(10-15)31-4/h8-11H,6-7,12H2,1-5H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM214716 (US9296747, Example 11) Show SMILES COc1cc(Nc2ncc3CN(CCc3n2)C(=O)c2occc2C)cc(OC)c1OC Show InChI InChI=1S/C22H24N4O5/c1-13-6-8-31-19(13)21(27)26-7-5-16-14(12-26)11-23-22(25-16)24-15-9-17(28-2)20(30-4)18(10-15)29-3/h6,8-11H,5,7,12H2,1-4H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144590 (US8969583, 6) Show SMILES NC(=O)c1c(NC(=O)NCCCN2CCOCC2)snc1-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1 Show InChI InChI=1S/C26H27F4N7O4S/c27-18-7-4-16(26(28,29)30)14-19(18)34-25(40)33-17-5-2-15(3-6-17)21-20(22(31)38)23(42-36-21)35-24(39)32-8-1-9-37-10-12-41-13-11-37/h2-7,14H,1,8-13H2,(H2,31,38)(H2,32,35,39)(H2,33,34,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144598 (US8969583, 48) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCC(O)=O)c2C(N)=O)cc1 Show InChI InChI=1S/C23H24N6O5S/c1-13-4-8-15(9-5-13)26-23(34)27-16-10-6-14(7-11-16)19-18(20(24)32)21(35-29-19)28-22(33)25-12-2-3-17(30)31/h4-11H,2-3,12H2,1H3,(H2,24,32)(H,30,31)(H2,25,28,33)(H2,26,27,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM144591 (US8969583, 7) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCOCC3)c2C(N)=O)cc1 Show InChI InChI=1S/C26H31N7O4S/c1-17-3-7-19(8-4-17)29-26(36)30-20-9-5-18(6-10-20)22-21(23(27)34)24(38-32-22)31-25(35)28-11-2-12-33-13-15-37-16-14-33/h3-10H,2,11-16H2,1H3,(H2,27,34)(H2,28,31,35)(H2,29,30,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144599 (US8969583, 56) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCO)c2C(N)=O)cc1 Show InChI InChI=1S/C22H24N6O4S/c1-13-3-7-15(8-4-13)25-22(32)26-16-9-5-14(6-10-16)18-17(19(23)30)20(33-28-18)27-21(31)24-11-2-12-29/h3-10,29H,2,11-12H2,1H3,(H2,23,30)(H2,24,27,31)(H2,25,26,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144587 (US8969583, 3) Show SMILES NC(=O)c1c(NC(=O)NCCCN2CCOCC2)snc1-c1ccc(NC(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C25H29N7O4S/c26-22(33)20-21(17-7-9-19(10-8-17)29-25(35)28-18-5-2-1-3-6-18)31-37-23(20)30-24(34)27-11-4-12-32-13-15-36-16-14-32/h1-3,5-10H,4,11-16H2,(H2,26,33)(H2,27,30,34)(H2,28,29,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144591 (US8969583, 7) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCOCC3)c2C(N)=O)cc1 Show InChI InChI=1S/C26H31N7O4S/c1-17-3-7-19(8-4-17)29-26(36)30-20-9-5-18(6-10-20)22-21(23(27)34)24(38-32-22)31-25(35)28-11-2-12-33-13-15-37-16-14-33/h3-10H,2,11-16H2,1H3,(H2,27,34)(H2,28,31,35)(H2,29,30,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM214718 (US9296747, Example 13) Show SMILES COc1cc(Nc2ncc3CN(CCc3n2)C(=O)c2cccs2)cc(OC)c1OC Show InChI InChI=1S/C21H22N4O4S/c1-27-16-9-14(10-17(28-2)19(16)29-3)23-21-22-11-13-12-25(7-6-15(13)24-21)20(26)18-5-4-8-30-18/h4-5,8-11H,6-7,12H2,1-3H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM144587 (US8969583, 3) Show SMILES NC(=O)c1c(NC(=O)NCCCN2CCOCC2)snc1-c1ccc(NC(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C25H29N7O4S/c26-22(33)20-21(17-7-9-19(10-8-17)29-25(35)28-18-5-2-1-3-6-18)31-37-23(20)30-24(34)27-11-4-12-32-13-15-36-16-14-32/h1-3,5-10H,4,11-16H2,(H2,26,33)(H2,27,30,34)(H2,28,29,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM214712 (US9296747, Example 7) Show SMILES COc1ccccc1Nc1ncc2CN(CCc2n1)C(=O)c1cccnc1 Show InChI InChI=1S/C20H19N5O2/c1-27-18-7-3-2-6-17(18)24-20-22-12-15-13-25(10-8-16(15)23-20)19(26)14-5-4-9-21-11-14/h2-7,9,11-12H,8,10,13H2,1H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144589 (US8969583, 5) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCOCC3)c2C(N)=O)c1 Show InChI InChI=1S/C26H31N7O4S/c1-17-4-2-5-20(16-17)30-26(36)29-19-8-6-18(7-9-19)22-21(23(27)34)24(38-32-22)31-25(35)28-10-3-11-33-12-14-37-15-13-33/h2,4-9,16H,3,10-15H2,1H3,(H2,27,34)(H2,28,31,35)(H2,29,30,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144598 (US8969583, 48) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCC(O)=O)c2C(N)=O)cc1 Show InChI InChI=1S/C23H24N6O5S/c1-13-4-8-15(9-5-13)26-23(34)27-16-10-6-14(7-11-16)19-18(20(24)32)21(35-29-19)28-22(33)25-12-2-3-17(30)31/h4-11H,2-3,12H2,1H3,(H2,24,32)(H,30,31)(H2,25,28,33)(H2,26,27,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144610 (US8969583, 68) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCCC3)c2C(N)=O)cc1 Show InChI InChI=1S/C26H31N7O3S/c1-17-5-9-19(10-6-17)29-26(36)30-20-11-7-18(8-12-20)22-21(23(27)34)24(37-32-22)31-25(35)28-13-4-16-33-14-2-3-15-33/h5-12H,2-4,13-16H2,1H3,(H2,27,34)(H2,28,31,35)(H2,29,30,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM144588 (US8969583, 4) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCOCC3)c2C(N)=O)c1 Show InChI InChI=1S/C26H30FN7O4S/c1-16-3-8-19(27)20(15-16)31-26(37)30-18-6-4-17(5-7-18)22-21(23(28)35)24(39-33-22)32-25(36)29-9-2-10-34-11-13-38-14-12-34/h3-8,15H,2,9-14H2,1H3,(H2,28,35)(H2,29,32,36)(H2,30,31,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM214714 (US9296747, Example 9) Show SMILES O=C(N1CCc2nc(Nc3ccsc3)ncc2C1)c1cccnc1 Show InChI InChI=1S/C17H15N5OS/c23-16(12-2-1-5-18-8-12)22-6-3-15-13(10-22)9-19-17(21-15)20-14-4-7-24-11-14/h1-2,4-5,7-9,11H,3,6,10H2,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144611 (US8969583, 69) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2snc(N)c2C(N)=O)c1 Show InChI InChI=1S/C18H16FN5O2S/c1-9-2-7-12(19)13(8-9)23-18(26)22-11-5-3-10(4-6-11)15-14(17(21)25)16(20)24-27-15/h2-8H,1H3,(H2,20,24)(H2,21,25)(H2,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144610 (US8969583, 68) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCCC3)c2C(N)=O)cc1 Show InChI InChI=1S/C26H31N7O3S/c1-17-5-9-19(10-6-17)29-26(36)30-20-11-7-18(8-12-20)22-21(23(27)34)24(37-32-22)31-25(35)28-13-4-16-33-14-2-3-15-33/h5-12H,2-4,13-16H2,1H3,(H2,27,34)(H2,28,31,35)(H2,29,30,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144591 (US8969583, 7) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCOCC3)c2C(N)=O)cc1 Show InChI InChI=1S/C26H31N7O4S/c1-17-3-7-19(8-4-17)29-26(36)30-20-9-5-18(6-10-20)22-21(23(27)34)24(38-32-22)31-25(35)28-11-2-12-33-13-15-37-16-14-33/h3-10H,2,11-16H2,1H3,(H2,27,34)(H2,28,31,35)(H2,29,30,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144599 (US8969583, 56) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCO)c2C(N)=O)cc1 Show InChI InChI=1S/C22H24N6O4S/c1-13-3-7-15(8-4-13)25-22(32)26-16-9-5-14(6-10-16)18-17(19(23)30)20(33-28-18)27-21(31)24-11-2-12-29/h3-10,29H,2,11-12H2,1H3,(H2,23,30)(H2,24,27,31)(H2,25,26,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM144590 (US8969583, 6) Show SMILES NC(=O)c1c(NC(=O)NCCCN2CCOCC2)snc1-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1 Show InChI InChI=1S/C26H27F4N7O4S/c27-18-7-4-16(26(28,29)30)14-19(18)34-25(40)33-17-5-2-15(3-6-17)21-20(22(31)38)23(42-36-21)35-24(39)32-8-1-9-37-10-12-41-13-11-37/h2-7,14H,1,8-13H2,(H2,31,38)(H2,32,35,39)(H2,33,34,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144588 (US8969583, 4) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCOCC3)c2C(N)=O)c1 Show InChI InChI=1S/C26H30FN7O4S/c1-16-3-8-19(27)20(15-16)31-26(37)30-18-6-4-17(5-7-18)22-21(23(28)35)24(39-33-22)32-25(36)29-9-2-10-34-11-13-38-14-12-34/h3-8,15H,2,9-14H2,1H3,(H2,28,35)(H2,29,32,36)(H2,30,31,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM214713 (US9296747, Example 8) Show SMILES Cn1nccc1Nc1ncc2CN(CCc2n1)C(=O)c1cccnc1 Show InChI InChI=1S/C17H17N7O/c1-23-15(4-7-20-23)22-17-19-10-13-11-24(8-5-14(13)21-17)16(25)12-3-2-6-18-9-12/h2-4,6-7,9-10H,5,8,11H2,1H3,(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM214710 (US9296747, Example 5) Show SMILES COc1ccc(Nc2ncc3CN(CCc3n2)C(=O)c2cccnc2)cc1 Show InChI InChI=1S/C20H19N5O2/c1-27-17-6-4-16(5-7-17)23-20-22-12-15-13-25(10-8-18(15)24-20)19(26)14-3-2-9-21-11-14/h2-7,9,11-12H,8,10,13H2,1H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM214717 (US9296747, Example 12) Show SMILES COc1cc(Nc2ncc3CN(CCc3n2)C(=O)c2cc(C)nn2C)cc(OC)c1OC Show InChI InChI=1S/C22H26N6O4/c1-13-8-17(27(2)26-13)21(29)28-7-6-16-14(12-28)11-23-22(25-16)24-15-9-18(30-3)20(32-5)19(10-15)31-4/h8-11H,6-7,12H2,1-5H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144587 (US8969583, 3) Show SMILES NC(=O)c1c(NC(=O)NCCCN2CCOCC2)snc1-c1ccc(NC(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C25H29N7O4S/c26-22(33)20-21(17-7-9-19(10-8-17)29-25(35)28-18-5-2-1-3-6-18)31-37-23(20)30-24(34)27-11-4-12-32-13-15-36-16-14-32/h1-3,5-10H,4,11-16H2,(H2,26,33)(H2,27,30,34)(H2,28,29,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144590 (US8969583, 6) Show SMILES NC(=O)c1c(NC(=O)NCCCN2CCOCC2)snc1-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1 Show InChI InChI=1S/C26H27F4N7O4S/c27-18-7-4-16(26(28,29)30)14-19(18)34-25(40)33-17-5-2-15(3-6-17)21-20(22(31)38)23(42-36-21)35-24(39)32-8-1-9-37-10-12-41-13-11-37/h2-7,14H,1,8-13H2,(H2,31,38)(H2,32,35,39)(H2,33,34,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144603 (US8969583, 60) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2nsc(N)c2C(N)=O)c1 Show InChI InChI=1S/C18H16FN5O2S/c1-9-2-7-12(19)13(8-9)23-18(26)22-11-5-3-10(4-6-11)15-14(16(20)25)17(21)27-24-15/h2-8H,21H2,1H3,(H2,20,25)(H2,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144612 (US8969583, 70) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2snc(NCCCN3CCOCC3)c2C(N)=O)c1 Show InChI InChI=1S/C25H29FN6O3S/c1-16-3-8-19(26)20(15-16)30-25(34)29-18-6-4-17(5-7-18)22-21(23(27)33)24(31-36-22)28-9-2-10-32-11-13-35-14-12-32/h3-8,15H,2,9-14H2,1H3,(H2,27,33)(H,28,31)(H2,29,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144595 (US8969583, 13) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(-c3nsc(NC(=O)NCCCN4CCOCC4)c3C(N)=O)c(C)c2)c1 Show InChI InChI=1S/C27H32FN7O4S/c1-16-4-7-20(28)21(14-16)32-27(38)31-18-5-6-19(17(2)15-18)23-22(24(29)36)25(40-34-23)33-26(37)30-8-3-9-35-10-12-39-13-11-35/h4-7,14-15H,3,8-13H2,1-2H3,(H2,29,36)(H2,30,33,37)(H2,31,32,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144593 (US8969583, 10) Show SMILES COCCCNC(=O)Nc1snc(c1C(N)=O)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1 Show InChI InChI=1S/C23H25FN6O4S/c1-13-4-9-16(24)17(12-13)28-23(33)27-15-7-5-14(6-8-15)19-18(20(25)31)21(35-30-19)29-22(32)26-10-3-11-34-2/h4-9,12H,3,10-11H2,1-2H3,(H2,25,31)(H2,26,29,32)(H2,27,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144588 (US8969583, 4) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCOCC3)c2C(N)=O)c1 Show InChI InChI=1S/C26H30FN7O4S/c1-16-3-8-19(27)20(15-16)31-26(37)30-18-6-4-17(5-7-18)22-21(23(28)35)24(39-33-22)32-25(36)29-9-2-10-34-11-13-38-14-12-34/h3-8,15H,2,9-14H2,1H3,(H2,28,35)(H2,29,32,36)(H2,30,31,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144611 (US8969583, 69) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2snc(N)c2C(N)=O)c1 Show InChI InChI=1S/C18H16FN5O2S/c1-9-2-7-12(19)13(8-9)23-18(26)22-11-5-3-10(4-6-11)15-14(17(21)25)16(20)24-27-15/h2-8H,1H3,(H2,20,24)(H2,21,25)(H2,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144596 (US8969583, 26) Show SMILES CCOC(=O)Nc1snc(c1C(N)=O)-c1ccc(NC(=O)Nc2cc(C)ccc2F)cc1 Show InChI InChI=1S/C21H20FN5O4S/c1-3-31-21(30)26-19-16(18(23)28)17(27-32-19)12-5-7-13(8-6-12)24-20(29)25-15-10-11(2)4-9-14(15)22/h4-10H,3H2,1-2H3,(H2,23,28)(H,26,30)(H2,24,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144602 (US8969583, 59) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(N)c2C(N)=O)cc1 Show InChI InChI=1S/C18H17N5O2S/c1-10-2-6-12(7-3-10)21-18(25)22-13-8-4-11(5-9-13)15-14(16(19)24)17(20)26-23-15/h2-9H,20H2,1H3,(H2,19,24)(H2,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144612 (US8969583, 70) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2snc(NCCCN3CCOCC3)c2C(N)=O)c1 Show InChI InChI=1S/C25H29FN6O3S/c1-16-3-8-19(26)20(15-16)30-25(34)29-18-6-4-17(5-7-18)22-21(23(27)33)24(31-36-22)28-9-2-10-32-11-13-35-14-12-32/h3-8,15H,2,9-14H2,1H3,(H2,27,33)(H,28,31)(H2,29,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144603 (US8969583, 60) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2nsc(N)c2C(N)=O)c1 Show InChI InChI=1S/C18H16FN5O2S/c1-9-2-7-12(19)13(8-9)23-18(26)22-11-5-3-10(4-6-11)15-14(16(20)25)17(21)27-24-15/h2-8H,21H2,1H3,(H2,20,25)(H2,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM214707 (US9296747, Example 2) Show SMILES COc1cc(Nc2ncc3CN(CCc3n2)C(=O)c2cccnc2)cc(OC)c1OC Show InChI InChI=1S/C22H23N5O4/c1-29-18-9-16(10-19(30-2)20(18)31-3)25-22-24-12-15-13-27(8-6-17(15)26-22)21(28)14-5-4-7-23-11-14/h4-5,7,9-12H,6,8,13H2,1-3H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	89	n/a	n/a	n/a	n/a	7.2	25
Allergan, Inc. US Patent					Assay Description Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144613 (US8969583, 71) Show SMILES COc1ccc(CNc2nsc(c2C(N)=O)-c2ccc(NC(=O)Nc3cc(C)ccc3F)cc2)c(OC)c1 Show InChI InChI=1S/C27H26FN5O4S/c1-15-4-11-20(28)21(12-15)32-27(35)31-18-8-5-16(6-9-18)24-23(25(29)34)26(33-38-24)30-14-17-7-10-19(36-2)13-22(17)37-3/h4-13H,14H2,1-3H3,(H2,29,34)(H,30,33)(H2,31,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	98	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM214713 (US9296747, Example 8) Show SMILES Cn1nccc1Nc1ncc2CN(CCc2n1)C(=O)c1cccnc1 Show InChI InChI=1S/C17H17N7O/c1-23-15(4-7-20-23)22-17-19-10-13-11-24(8-5-14(13)21-17)16(25)12-3-2-6-18-9-12/h2-4,6-7,9-10H,5,8,11H2,1H3,(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM214721 (US9296747, Example 17) Show SMILES COc1cc(Nc2ncc3CN(CCc3n2)C(=O)c2cccnc2)cc(OC)c1 Show InChI InChI=1S/C21H21N5O3/c1-28-17-8-16(9-18(10-17)29-2)24-21-23-12-15-13-26(7-5-19(15)25-21)20(27)14-4-3-6-22-11-14/h3-4,6,8-12H,5,7,13H2,1-2H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	7.2	25
Allergan, Inc. US Patent					Assay Description Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM214720 (US9296747, Example 16) Show SMILES COc1ccc(Nc2ncc3CN(CCc3n2)C(=O)c2cccnc2)cc1OC Show InChI InChI=1S/C21H21N5O3/c1-28-18-6-5-16(10-19(18)29-2)24-21-23-12-15-13-26(9-7-17(15)25-21)20(27)14-4-3-8-22-11-14/h3-6,8,10-12H,7,9,13H2,1-2H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	176	n/a	n/a	n/a	n/a	7.2	25
Allergan, Inc. US Patent					Assay Description Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144602 (US8969583, 59) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(N)c2C(N)=O)cc1 Show InChI InChI=1S/C18H17N5O2S/c1-10-2-6-12(7-3-10)21-18(25)22-13-8-4-11(5-9-13)15-14(16(19)24)17(20)26-23-15/h2-9H,20H2,1H3,(H2,19,24)(H2,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	176	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM214716 (US9296747, Example 11) Show SMILES COc1cc(Nc2ncc3CN(CCc3n2)C(=O)c2occc2C)cc(OC)c1OC Show InChI InChI=1S/C22H24N4O5/c1-13-6-8-31-19(13)21(27)26-7-5-16-14(12-26)11-23-22(25-16)24-15-9-17(28-2)20(30-4)18(10-15)29-3/h6,8-11H,5,7,12H2,1-4H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	239	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM214712 (US9296747, Example 7) Show SMILES COc1ccccc1Nc1ncc2CN(CCc2n1)C(=O)c1cccnc1 Show InChI InChI=1S/C20H19N5O2/c1-27-18-7-3-2-6-17(18)24-20-22-12-15-13-25(10-8-16(15)23-20)19(26)14-5-4-9-21-11-14/h2-7,9,11-12H,8,10,13H2,1H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	244	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM236231 (US9365575, 9) Show SMILES Brc1cccc(NC(=O)Nc2ccc(cc2)C2CN=C3N(C2)C(=O)Nc2ccccc32)c1 |c:19| Show InChI InChI=1S/C24H20BrN5O2/c25-17-4-3-5-19(12-17)28-23(31)27-18-10-8-15(9-11-18)16-13-26-22-20-6-1-2-7-21(20)29-24(32)30(22)14-16/h1-12,16H,13-14H2,(H,29,32)(H2,27,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US9365575 (2016) BindingDB Entry DOI: 10.7270/Q2J96592
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM214715 (US9296747, Example 10) Show SMILES Fc1cccc(Nc2ncc3CN(CCc3n2)C(=O)c2cccnc2)c1 Show InChI InChI=1S/C19H16FN5O/c20-15-4-1-5-16(9-15)23-19-22-11-14-12-25(8-6-17(14)24-19)18(26)13-3-2-7-21-10-13/h1-5,7,9-11H,6,8,12H2,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	274	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US9296747 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VGX
					More data for this Ligand-Target Pair

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