Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA ligase 1 (Homo sapiens (Human)) | BDBM22826 (2,3-dioxo-2,3-dihydro-1H-indole-7-carboxylic acid ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA ligase 1 using nicked DNA substrate by kinetic assay | J Med Chem 51: 4553-62 (2008) Article DOI: 10.1021/jm8001668 BindingDB Entry DOI: 10.7270/Q2639PJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50262041 (5-(((5-carboxy-2-methylfuran-3-yl)methylthio)methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assay | J Med Chem 51: 4553-62 (2008) Article DOI: 10.1021/jm8001668 BindingDB Entry DOI: 10.7270/Q2639PJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50262039 (3-amino-2-(benzylideneamino)-5-mercaptophenol | CH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assay | J Med Chem 51: 4553-62 (2008) Article DOI: 10.1021/jm8001668 BindingDB Entry DOI: 10.7270/Q2639PJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM22826 (2,3-dioxo-2,3-dihydro-1H-indole-7-carboxylic acid ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assay | J Med Chem 51: 4553-62 (2008) Article DOI: 10.1021/jm8001668 BindingDB Entry DOI: 10.7270/Q2639PJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50261995 (CHEMBL467192 | N'-(2-hydroxy-5-nitrobenzylidene)-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assay | J Med Chem 51: 4553-62 (2008) Article DOI: 10.1021/jm8001668 BindingDB Entry DOI: 10.7270/Q2639PJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50262038 (3-(4-Bromo-benzenesulfonyl)-N-[2-(4-sulfamoyl-phen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assay | J Med Chem 51: 4553-62 (2008) Article DOI: 10.1021/jm8001668 BindingDB Entry DOI: 10.7270/Q2639PJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50261993 (5-(methylthio)thiophene-2-carboxylic acid | CHEMBL...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assay | J Med Chem 51: 4553-62 (2008) Article DOI: 10.1021/jm8001668 BindingDB Entry DOI: 10.7270/Q2639PJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50262037 (5-(2-(4-hydroxy-3-nitrobenzylidene)hydrazinyl)-4-c...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assay | J Med Chem 51: 4553-62 (2008) Article DOI: 10.1021/jm8001668 BindingDB Entry DOI: 10.7270/Q2639PJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50261994 (2-(7-chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-ylth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assay | J Med Chem 51: 4553-62 (2008) Article DOI: 10.1021/jm8001668 BindingDB Entry DOI: 10.7270/Q2639PJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50262040 (7-(4-methoxyphenyl)pteridine-2,4-diol | CHEMBL5112...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assay | J Med Chem 51: 4553-62 (2008) Article DOI: 10.1021/jm8001668 BindingDB Entry DOI: 10.7270/Q2639PJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50262042 ((2-hydroxyphenyl)(4-hydroxyphenyl)methanone | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assay | J Med Chem 51: 4553-62 (2008) Article DOI: 10.1021/jm8001668 BindingDB Entry DOI: 10.7270/Q2639PJC | |||||||||||
More data for this Ligand-Target Pair |