Found 35 hits with Last Name = 'sangshetti' and Initial = 'jn' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50468271
(CHEMBL4290134)Show InChI InChI=1S/C18H18N2O/c1-18(2,3)13-10-8-12(9-11-13)16-19-15-7-5-4-6-14(15)17(21)20-16/h4-11H,1-3H3,(H,19,20,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| Purchase
PC cid
PC sid
PDB
UniChem
| | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50612120
(CHEMBL5275705)Show SMILES CC1(NC(=O)NC1=O)c1ccc(cc1)-c1nc2ccccc2c(=O)[nH]1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50505333
(CHEMBL4437173)Show SMILES CC(C)(O)c1ccc(cc1)-c1nc2c(F)cc(F)cc2c(=O)[nH]1 Show InChI InChI=1S/C17H14F2N2O2/c1-17(2,23)10-5-3-9(4-6-10)15-20-14-12(16(22)21-15)7-11(18)8-13(14)19/h3-8,23H,1-2H3,(H,20,21,22) | PDB
UniProtKB/SwissProt
antibodypedia
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MCE
PC cid
PC sid
PDB
UniChem
| PDB
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50019166
(CHEMBL336718)Show InChI InChI=1S/C15H12N2O2/c1-19-11-8-6-10(7-9-11)14-16-13-5-3-2-4-12(13)15(18)17-14/h2-9H,1H3,(H,16,17,18) | PDB
UniProtKB/SwissProt
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50505333
(CHEMBL4437173)Show SMILES CC(C)(O)c1ccc(cc1)-c1nc2c(F)cc(F)cc2c(=O)[nH]1 Show InChI InChI=1S/C17H14F2N2O2/c1-17(2,23)10-5-3-9(4-6-10)15-20-14-12(16(22)21-15)7-11(18)8-13(14)19/h3-8,23H,1-2H3,(H,20,21,22) | PDB
UniProtKB/SwissProt
antibodypedia
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PC cid
PC sid
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UniChem
| PDB
| n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50188337
(CHEMBL2058057)Show InChI InChI=1S/C14H9BrN2O/c15-10-7-5-9(6-8-10)13-16-12-4-2-1-3-11(12)14(18)17-13/h1-8H,(H,16,17,18) | PDB
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| | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50511566
(CHEMBL4448872)Show SMILES OCCN1CC2(CCN(CC2)c2nc3CCCCc3c(=O)[nH]2)c2c1cc(F)cc2F Show InChI InChI=1S/C22H26F2N4O2/c23-14-11-16(24)19-18(12-14)28(9-10-29)13-22(19)5-7-27(8-6-22)21-25-17-4-2-1-3-15(17)20(30)26-21/h11-12,29H,1-10,13H2,(H,25,26,30) | PDB
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antibodypedia
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| PDB
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50612121
(CHEMBL5277753) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50511566
(CHEMBL4448872)Show SMILES OCCN1CC2(CCN(CC2)c2nc3CCCCc3c(=O)[nH]2)c2c1cc(F)cc2F Show InChI InChI=1S/C22H26F2N4O2/c23-14-11-16(24)19-18(12-14)28(9-10-29)13-22(19)5-7-27(8-6-22)21-25-17-4-2-1-3-15(17)20(30)26-21/h11-12,29H,1-10,13H2,(H,25,26,30) | PDB
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antibodypedia
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UniChem
| PDB
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50612117
(CHEMBL5270676) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50612118
(CHEMBL3431396)Show SMILES O=C(Nc1ccc(cc1)-c1nc2ccccc2c(=O)[nH]1)c1cccs1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50612119
(CHEMBL5267866) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
DNA topoisomerase 2-alpha
(Homo sapiens (Human)) | BDBM22984
((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)Show SMILES COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO |r| Show InChI InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1 | PDB
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PC cid
PC sid
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UniChem
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Similars
| Article
PubMed
| n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uM |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127916
BindingDB Entry DOI: 10.7270/Q2VQ36GH |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179406
(CHEMBL3814850)Show SMILES CCCc1nc2ccc(Cl)cc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H21ClN6/c1-2-5-23-26-21-13-12-18(25)14-22(21)31(23)15-16-8-10-17(11-9-16)19-6-3-4-7-20(19)24-27-29-30-28-24/h3-4,6-14H,2,5,15H2,1H3,(H,27,28,29,30) | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of Escherichia coli peptide deformylase |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
DNA topoisomerase 2-alpha
(Homo sapiens (Human)) | BDBM50570427
(CHEMBL4864715)Show SMILES NC1=C(C#N)C(c2cc3ccccc3s2)c2c(O1)c1ccccc1oc2=O |c:1| | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uM |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127916
BindingDB Entry DOI: 10.7270/Q2VQ36GH |
More data for this
Ligand-Target Pair | |
DNA topoisomerase 2-alpha
(Homo sapiens (Human)) | BDBM50570429
(CHEMBL4878037)Show SMILES NC1=C(C#N)C(c2c[nH]c3ccccc23)c2c(O1)c1ccccc1oc2=O |c:1| | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uM |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127916
BindingDB Entry DOI: 10.7270/Q2VQ36GH |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179404
(CHEMBL3814663)Show InChI InChI=1S/C20H16N2/c21-14-18-6-4-5-9-20(18)17-12-10-16(11-13-17)15-22-19-7-2-1-3-8-19/h1-13,22H,15H2 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179409
(CHEMBL3814475)Show SMILES [O-][N+](=O)c1ccccc1NCc1ccc(cc1)-c1ccccc1C#N Show InChI InChI=1S/C20H15N3O2/c21-13-17-5-1-2-6-18(17)16-11-9-15(10-12-16)14-22-19-7-3-4-8-20(19)23(24)25/h1-12,22H,14H2 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
DNA topoisomerase 2-alpha
(Homo sapiens (Human)) | BDBM50570428
(CHEMBL4870551)Show SMILES NC1=C(C#N)C(c2cnc3ccccc3c2)c2c(O1)c1ccccc1oc2=O |c:1| | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.67E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uM |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127916
BindingDB Entry DOI: 10.7270/Q2VQ36GH |
More data for this
Ligand-Target Pair | |
DNA topoisomerase 2-alpha
(Homo sapiens (Human)) | BDBM50570432
(CHEMBL4849502)Show SMILES Cc1cc2occ(-c3nc(c(-c4ccccc4)n3-c3ccc(Br)cc3)-c3ccccc3)c(=O)c2cc1Cl | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uM |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127916
BindingDB Entry DOI: 10.7270/Q2VQ36GH |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179402
(CHEMBL3814494)Show InChI InChI=1S/C18H14N4/c19-11-16-3-1-2-4-17(16)15-7-5-14(6-8-15)12-22-18-13-20-9-10-21-18/h1-10,13H,12H2,(H,21,22) | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179429
(CHEMBL3814111)Show InChI InChI=1S/C21H15F3N2/c22-21(23,24)18-5-3-6-19(12-18)26-14-15-8-10-16(11-9-15)20-7-2-1-4-17(20)13-25/h1-12,26H,14H2 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179410
(CHEMBL3815111)Show SMILES CCCC1=NC2N(N=C(C)C=C2C)C1Cc1ccc(cc1)-c1ccccc1C(O)=O |c:10,t:3,7| Show InChI InChI=1S/C25H27N3O2/c1-4-7-22-23(28-24(26-22)16(2)14-17(3)27-28)15-18-10-12-19(13-11-18)20-8-5-6-9-21(20)25(29)30/h5-6,8-14,23-24H,4,7,15H2,1-3H3,(H,29,30) | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of Escherichia coli peptide deformylase |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179408
(CHEMBL3814560)Show SMILES [O-][N+](=O)c1cccc(NCc2ccc(cc2)-c2ccccc2C#N)c1 Show InChI InChI=1S/C20H15N3O2/c21-13-17-4-1-2-7-20(17)16-10-8-15(9-11-16)14-22-18-5-3-6-19(12-18)23(24)25/h1-12,22H,14H2 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
DNA topoisomerase 2-alpha
(Homo sapiens (Human)) | BDBM50570430
(CHEMBL4855587)Show SMILES NC1=C(C#N)C(c2cc(=O)c3ccccc3o2)c2c(O1)c1ccccc1oc2=O |c:1| | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uM |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127916
BindingDB Entry DOI: 10.7270/Q2VQ36GH |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179400
(CHEMBL3814987)Show InChI InChI=1S/C22H17N3OS/c1-26-18-10-11-20-21(12-18)27-22(25-20)24-14-15-6-8-16(9-7-15)19-5-3-2-4-17(19)13-23/h2-12H,14H2,1H3,(H,24,25) | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179411
(CHEMBL3815003)Show SMILES [O-][N+](=O)c1cc(Cl)ccc1NCc1ccc(cc1)-c1ccccc1C#N Show InChI InChI=1S/C20H14ClN3O2/c21-17-9-10-19(20(11-17)24(25)26)23-13-14-5-7-15(8-6-14)18-4-2-1-3-16(18)12-22/h1-11,23H,13H2 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179407
(CHEMBL3814606)Show InChI InChI=1S/C20H16N2O/c21-13-17-5-1-2-6-18(17)16-11-9-15(10-12-16)14-22-19-7-3-4-8-20(19)23/h1-12,22-23H,14H2 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179412
(CHEMBL3814562)Show InChI InChI=1S/C21H15F3N2/c22-21(23,24)18-9-11-19(12-10-18)26-14-15-5-7-16(8-6-15)20-4-2-1-3-17(20)13-25/h1-12,26H,14H2 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179405
(CHEMBL3814751)Show InChI InChI=1S/C20H16N2O/c21-13-17-3-1-2-4-20(17)16-7-5-15(6-8-16)14-22-18-9-11-19(23)12-10-18/h1-12,22-23H,14H2 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
DNA topoisomerase 2-alpha
(Homo sapiens (Human)) | BDBM50570431
(CHEMBL4869150)Show SMILES Cc1cc2occ(-c3nc(c(-c4ccccc4)n3-c3ccc(Cl)c(Cl)c3)-c3ccccc3)c(=O)c2cc1Cl | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.99E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uM |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127916
BindingDB Entry DOI: 10.7270/Q2VQ36GH |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179399
(CHEMBL3814600)Show SMILES Fc1cc(NCc2ccc(cc2)-c2ccccc2C#N)ccc1N1CCOCC1 Show InChI InChI=1S/C24H22FN3O/c25-23-15-21(9-10-24(23)28-11-13-29-14-12-28)27-17-18-5-7-19(8-6-18)22-4-2-1-3-20(22)16-26/h1-10,15,27H,11-14,17H2 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
DNA topoisomerase 2-alpha
(Homo sapiens (Human)) | BDBM50570433
(CHEMBL4853443)Show SMILES Cc1cc2occ(-c3nc(c(-c4ccccc4)n3-c3ccc(cc3)[N+]([O-])=O)-c3ccccc3)c(=O)c2cc1Cl | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uM |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127916
BindingDB Entry DOI: 10.7270/Q2VQ36GH |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179401
(CHEMBL3814164)Show InChI InChI=1S/C16H13N5/c17-9-15-3-1-2-4-16(15)14-7-5-13(6-8-14)10-20-21-11-18-19-12-21/h1-8,11-12,20H,10H2 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
Peptide deformylase
(Escherichia coli) | BDBM50179428
(CHEMBL3814974)Show InChI InChI=1S/C21H16N2O2/c22-13-18-3-1-2-4-20(18)16-7-5-15(6-8-16)14-23-19-11-9-17(10-12-19)21(24)25/h1-12,23H,14H2,(H,24,25) | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Y.B. Chavan College of Pharmacy
Curated by ChEMBL
| Assay Description
Inhibition of NiCl2 stabilized Escherichia coli NCIM-2931 peptide deformylase using N-formyl-Met-Ala as substrate incubated for 30 mins by spectropho... |
Bioorg Med Chem 24: 3456-63 (2016)
Article DOI: 10.1016/j.bmc.2016.05.051
BindingDB Entry DOI: 10.7270/Q2J67JV4 |
More data for this
Ligand-Target Pair | |
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