BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 49 hits with Last Name = 'demers' and Initial = 'jp'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50229951
PNG
(CHEMBL49458)
Show SMILES CC1CC(=O)NN=C1c1ccc2NC(=O)CSc2c1 |c:6|
Show InChI InChI=1S/C13H13N3O2S/c1-7-4-11(17)15-16-13(7)8-2-3-9-10(5-8)19-6-12(18)14-9/h2-3,5,7H,4,6H2,1H3,(H,14,18)(H,15,17)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
PubMed
n/an/a 100n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac Phosphodiesterase 3

J Med Chem 35: 172-6 (1992)


BindingDB Entry DOI: 10.7270/Q2NS0X4D
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50226407
PNG
(CHEMBL299631 | Y-590)
Show SMILES CC1CC(=O)NN=C1c1ccc2N(C)C(=O)CCc2c1 |c:6|
Show InChI InChI=1S/C15H17N3O2/c1-9-7-13(19)16-17-15(9)11-3-5-12-10(8-11)4-6-14(20)18(12)2/h3,5,8-9H,4,6-7H2,1-2H3,(H,16,19)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 100n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac Phosphodiesterase 3

J Med Chem 35: 172-6 (1992)


BindingDB Entry DOI: 10.7270/Q2NS0X4D
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50228430
PNG
(Bemoradan | ORF-22867)
Show SMILES CC1CC(=O)NN=C1c1ccc2NC(=O)COc2c1 |c:6|
Show InChI InChI=1S/C13H13N3O3/c1-7-4-11(17)15-16-13(7)8-2-3-9-10(5-8)19-6-12(18)14-9/h2-3,5,7H,4,6H2,1H3,(H,14,18)(H,15,17)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
MCE
PC cid
PC sid
UniChem
PubMed
n/an/a 300n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac Phosphodiesterase 3

J Med Chem 35: 172-6 (1992)


BindingDB Entry DOI: 10.7270/Q2NS0X4D
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50229946
PNG
(CHEMBL52168)
Show SMILES CC1CC(=O)NN=C1c1ccc2NC(=O)CCc2c1 |c:6|
Show InChI InChI=1S/C14H15N3O2/c1-8-6-13(19)16-17-14(8)10-2-4-11-9(7-10)3-5-12(18)15-11/h2,4,7-8H,3,5-6H2,1H3,(H,15,18)(H,16,19)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 300n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac Phosphodiesterase 3

J Med Chem 35: 172-6 (1992)


BindingDB Entry DOI: 10.7270/Q2NS0X4D
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50228431
PNG
(CHEMBL49406)
Show SMILES CC1CC(=O)NN=C1c1ccc2N(C)C(=O)COc2c1 |c:6|
Show InChI InChI=1S/C14H15N3O3/c1-8-5-12(18)15-16-14(8)9-3-4-10-11(6-9)20-7-13(19)17(10)2/h3-4,6,8H,5,7H2,1-2H3,(H,15,18)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 300n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac Phosphodiesterase 3

J Med Chem 35: 172-6 (1992)


BindingDB Entry DOI: 10.7270/Q2NS0X4D
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50229948
PNG
(CHEMBL294939)
Show SMILES CC1CC(=O)NN=C1c1ccc2N(C)C(=O)CSc2c1 |c:6|
Show InChI InChI=1S/C14H15N3O2S/c1-8-5-12(18)15-16-14(8)9-3-4-10-11(6-9)20-7-13(19)17(10)2/h3-4,6,8H,5,7H2,1-2H3,(H,15,18)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac Phosphodiesterase 3

J Med Chem 35: 172-6 (1992)


BindingDB Entry DOI: 10.7270/Q2NS0X4D
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50229952
PNG
(CHEMBL49533)
Show SMILES CC1CC(=O)NN=C1c1ccc2NC(=O)C[Se]c2c1 |c:6|
Show InChI InChI=1S/C13H13N3O2Se/c1-7-4-11(17)15-16-13(7)8-2-3-9-10(5-8)19-6-12(18)14-9/h2-3,5,7H,4,6H2,1H3,(H,14,18)(H,15,17)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac Phosphodiesterase 3

J Med Chem 35: 172-6 (1992)


BindingDB Entry DOI: 10.7270/Q2NS0X4D
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471725
PNG
(CHEMBL327734)
Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cccc(O)c1O
Show InChI InChI=1S/C22H16Cl2N2O3/c1-12-9-16(17(11-25)13-5-7-14(23)8-6-13)18(24)10-19(12)26-22(29)15-3-2-4-20(27)21(15)28/h2-10,17,27-28H,1H3,(H,26,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50063753
PNG
(CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...)
Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O
Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 3.80E+3n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215968
PNG
(CHEMBL57324)
Show SMILES Cc1cc(NC(=O)c2cc(I)cc(I)c2O)c(Cl)cc1C(C#N)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-20(28-22(30)16-7-14(25)8-19(26)21(16)29)18(24)9-15(11)17(10-27)12-2-4-13(23)5-3-12/h2-9,17,29H,1H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.80E+3n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471718
PNG
(CHEMBL98026)
Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(Cl)cc(Cl)c1O
Show InChI InChI=1S/C22H14Cl4N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(25)9-20(11)28-22(30)16-7-14(24)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.80E+3n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215967
PNG
(CHEMBL56579)
Show SMILES Cc1cc(NC(=O)c2cc(Cl)cc(Cl)c2O)c(Cl)cc1C(C#N)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H14Cl4N2O2/c1-11-6-20(28-22(30)16-7-14(24)8-19(26)21(16)29)18(25)9-15(11)17(10-27)12-2-4-13(23)5-3-12/h2-9,17,29H,1H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 4.80E+3n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50229949
PNG
(CHEMBL294914)
Show SMILES O=C1CCC(=NN1)c1ccc2NC(=O)CSc2c1 |c:4|
Show InChI InChI=1S/C12H11N3O2S/c16-11-4-3-8(14-15-11)7-1-2-9-10(5-7)18-6-12(17)13-9/h1-2,5H,3-4,6H2,(H,13,17)(H,15,16)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
PubMed
n/an/a 7.00E+3n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac Phosphodiesterase 3

J Med Chem 35: 172-6 (1992)


BindingDB Entry DOI: 10.7270/Q2NS0X4D
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471730
PNG
(CHEMBL101786)
Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(cc(c1O)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C24H14Cl2F6N2O2/c1-11-6-15(17(10-33)12-2-4-14(25)5-3-12)19(26)9-20(11)34-22(36)16-7-13(23(27,28)29)8-18(21(16)35)24(30,31)32/h2-9,17,35H,1H3,(H,34,36)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation initiation phosphotransferase F/kinase A


(Bacillus subtilis (strain 168))		BDBM50215963
PNG
(CHEMBL57687)
Show SMILES Cc1cc(NC(=O)c2cc(I)c(O)c(I)c2)c(Cl)cc1C(C#N)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H14Cl2I2N2O2/c1-11-6-20(28-22(30)13-7-18(25)21(29)19(26)8-13)17(24)9-15(11)16(10-27)12-2-4-14(23)5-3-12/h2-9,16,29H,1H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471728
PNG
(CHEMBL100719)
Show SMILES Oc1cccc(C(=O)Nc2ccc(Cl)c(Cl)c2)c1O
Show InChI InChI=1S/C13H9Cl2NO3/c14-9-5-4-7(6-10(9)15)16-13(19)8-2-1-3-11(17)12(8)18/h1-6,17-18H,(H,16,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.50E+3n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471723
PNG
(CHEMBL98273)
Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(ccc1O)C(F)(F)F
Show InChI InChI=1S/C23H15Cl2F3N2O2/c1-12-8-16(18(11-29)13-2-5-15(24)6-3-13)19(25)10-20(12)30-22(32)17-9-14(23(26,27)28)4-7-21(17)31/h2-10,18,31H,1H3,(H,30,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50065970
PNG
(CHEMBL57656 | N-(3,4-Dichloro-phenyl)-2-hydroxy-3,...)
Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H7Cl2I2NO2/c14-9-2-1-7(5-10(9)15)18-13(20)8-3-6(16)4-11(17)12(8)19/h1-5,19H,(H,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.10E+4n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50065970
PNG
(CHEMBL57656 | N-(3,4-Dichloro-phenyl)-2-hydroxy-3,...)
Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H7Cl2I2NO2/c14-9-2-1-7(5-10(9)15)18-13(20)8-3-6(16)4-11(17)12(8)19/h1-5,19H,(H,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 2.20E+4n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471716
PNG
(CHEMBL431272)
Show SMILES Oc1c(cc(cc1C(F)(F)F)C(F)(F)F)C(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C15H7Cl2F6NO2/c16-10-2-1-7(5-11(10)17)24-13(26)8-3-6(14(18,19)20)4-9(12(8)25)15(21,22)23/h1-5,25H,(H,24,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.70E+4n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50229954
PNG
(CHEMBL52041)
Show SMILES CN1C(=O)CSc2cc(ccc12)C1=NNC(=O)CC1 |t:14|
Show InChI InChI=1S/C13H13N3O2S/c1-16-10-4-2-8(6-11(10)19-7-13(16)18)9-3-5-12(17)15-14-9/h2,4,6H,3,5,7H2,1H3,(H,15,17)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac Phosphodiesterase 3

J Med Chem 35: 172-6 (1992)


BindingDB Entry DOI: 10.7270/Q2NS0X4D
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50229950
PNG
(CHEMBL297940)
Show SMILES CN1C(=O)CS(=O)(=O)c2cc(ccc12)C1=NNC(=O)CC1 |t:16|
Show InChI InChI=1S/C13H13N3O4S/c1-16-10-4-2-8(9-3-5-12(17)15-14-9)6-11(10)21(19,20)7-13(16)18/h2,4,6H,3,5,7H2,1H3,(H,15,17)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 4.00E+4n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac Phosphodiesterase 3

J Med Chem 35: 172-6 (1992)


BindingDB Entry DOI: 10.7270/Q2NS0X4D
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215974
PNG
(3,3'',4'',5-tetrachlorosalicylanilide | 3,3',4',5-...)
Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H7Cl4NO2/c14-6-3-8(12(19)11(17)4-6)13(20)18-7-1-2-9(15)10(16)5-7/h1-5,19H,(H,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 4.50E+4n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50229947
PNG
(CHEMBL49527)
Show SMILES CN1C(=O)C[S+]([O-])c2cc(ccc12)C1=NNC(=O)CC1 |t:15|
Show InChI InChI=1S/C13H13N3O3S/c1-16-10-4-2-8(9-3-5-12(17)15-14-9)6-11(10)20(19)7-13(16)18/h2,4,6H,3,5,7H2,1H3,(H,15,17)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 4.50E+4n/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of canine cardiac Phosphodiesterase 3

J Med Chem 35: 172-6 (1992)


BindingDB Entry DOI: 10.7270/Q2NS0X4D
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215974
PNG
(3,3'',4'',5-tetrachlorosalicylanilide | 3,3',4',5-...)
Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H7Cl4NO2/c14-6-3-8(12(19)11(17)4-6)13(20)18-7-1-2-9(15)10(16)5-7/h1-5,19H,(H,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 4.50E+4n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471712
PNG
(CHEMBL319252)
Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C14H7Cl3F3NO2/c15-6-3-8(12(22)11(17)4-6)13(23)21-7-1-2-10(16)9(5-7)14(18,19)20/h1-5,22H,(H,21,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.00E+4n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471719
PNG
(CHEMBL100688)
Show SMILES CC(C)(C)c1ccc(NC(=O)c2cc(Cl)cc(Cl)c2O)cc1
Show InChI InChI=1S/C17H17Cl2NO2/c1-17(2,3)10-4-6-12(7-5-10)20-16(22)13-8-11(18)9-14(19)15(13)21/h4-9,21H,1-3H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.70E+4n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471713
PNG
(CHEMBL99708)
Show SMILES Cc1cc(C(CN)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O
Show InChI InChI=1S/C22H18Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,10,27H2,1H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.60E+4n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215970
PNG
(CHEMBL56781)
Show SMILES Oc1c(Cl)cc(cc1Cl)C(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H7Cl4NO2/c14-8-2-1-7(5-9(8)15)18-13(20)6-3-10(16)12(19)11(17)4-6/h1-5,19H,(H,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 9.80E+4n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50065988
PNG
(3,5-Dichloro-N-(4-chloro-phenyl)-2-hydroxy-benzami...)
Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C13H8Cl3NO2/c14-7-1-3-9(4-2-7)17-13(19)10-5-8(15)6-11(16)12(10)18/h1-6,18H,(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.85E+5n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471724
PNG
(CHEMBL98743)
Show SMILES COc1cc(OC)c(O)c(c1)C(=O)Nc1cc(Cl)c(cc1C)C(C#N)c1ccc(Cl)cc1
Show InChI InChI=1S/C24H20Cl2N2O4/c1-13-8-17(19(12-27)14-4-6-15(25)7-5-14)20(26)11-21(13)28-24(30)18-9-16(31-2)10-22(32-3)23(18)29/h4-11,19,29H,1-3H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.50E+5n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215972
PNG
(CHEMBL57827)
Show SMILES Oc1c(Cl)cc(Cl)cc1NC(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H8Cl4N2O2/c14-6-3-10(17)12(20)11(4-6)19-13(21)18-7-1-2-8(15)9(16)5-7/h1-5,20H,(H2,18,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.65E+5n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215971
PNG
(CHEMBL299692)
Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccccc1
Show InChI InChI=1S/C13H9Cl2NO2/c14-8-6-10(12(17)11(15)7-8)13(18)16-9-4-2-1-3-5-9/h1-7,17H,(H,16,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 3.85E+5n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215971
PNG
(CHEMBL299692)
Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccccc1
Show InChI InChI=1S/C13H9Cl2NO2/c14-8-6-10(12(17)11(15)7-8)13(18)16-9-4-2-1-3-5-9/h1-7,17H,(H,16,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471729
PNG
(CHEMBL419162)
Show SMILES CC(C)(C)c1cc(C(=O)Nc2ccc(Cl)c(Cl)c2)c(O)c(c1)C(C)(C)C
Show InChI InChI=1S/C21H25Cl2NO2/c1-20(2,3)12-9-14(18(25)15(10-12)21(4,5)6)19(26)24-13-7-8-16(22)17(23)11-13/h7-11,25H,1-6H3,(H,24,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471727
PNG
(CHEMBL318371)
Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C13H8Cl2N2O4/c14-7-5-10(12(18)11(15)6-7)13(19)16-8-1-3-9(4-2-8)17(20)21/h1-6,18H,(H,16,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471726
PNG
(CHEMBL100633)
Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H8Cl3NO2/c14-7-1-4-12(18)9(5-7)13(19)17-8-2-3-10(15)11(16)6-8/h1-6,18H,(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471722
PNG
(CHEMBL330654)
Show SMILES Oc1ccc(cc1C(=O)Nc1ccc(Cl)c(Cl)c1)C(F)(F)F
Show InChI InChI=1S/C14H8Cl2F3NO2/c15-10-3-2-8(6-11(10)16)20-13(22)9-5-7(14(17,18)19)1-4-12(9)21/h1-6,21H,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471721
PNG
(CHEMBL319962)
Show SMILES COc1cc(OC)c(O)c(c1)C(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C15H13Cl2NO4/c1-21-9-6-10(14(19)13(7-9)22-2)15(20)18-8-3-4-11(16)12(17)5-8/h3-7,19H,1-2H3,(H,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471720
PNG
(CHEMBL319852)
Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(cc(c1O)C(C)(C)C)C(C)(C)C
Show InChI InChI=1S/C30H32Cl2N2O2/c1-17-12-21(23(16-33)18-8-10-20(31)11-9-18)25(32)15-26(17)34-28(36)22-13-19(29(2,3)4)14-24(27(22)35)30(5,6)7/h8-15,23,35H,1-7H3,(H,34,36)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471717
PNG
(CHEMBL101264)
Show SMILES Cc1cc(C(=O)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O
Show InChI InChI=1S/C21H13Cl2I2NO3/c1-10-6-14(19(27)11-2-4-12(22)5-3-11)16(23)9-18(10)26-21(29)15-7-13(24)8-17(25)20(15)28/h2-9,28H,1H3,(H,26,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471715
PNG
(CHEMBL431816)
Show SMILES Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(Cl)ccc1O
Show InChI InChI=1S/C22H15Cl3N2O2/c1-12-8-16(18(11-26)13-2-4-14(23)5-3-13)19(25)10-20(12)27-22(29)17-9-15(24)6-7-21(17)28/h2-10,18,28H,1H3,(H,27,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50471714
PNG
(CHEMBL330397)
Show SMILES COc1ccc(NC(=O)c2cc(Cl)cc(Cl)c2O)cc1
Show InChI InChI=1S/C14H11Cl2NO3/c1-20-10-4-2-9(3-5-10)17-14(19)11-6-8(15)7-12(16)13(11)18/h2-7,18H,1H3,(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of autophosphorylation of the two-component signal transduction system kinase was measured using the KinA/Spo0F regulatory system of Bacil...

J Med Chem 41: 2939-45 (1998)


Article DOI: 10.1021/jm9803572
BindingDB Entry DOI: 10.7270/Q2VM4G0W
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215975
PNG
(CHEMBL57526)
Show SMILES CN(C(=O)c1cc(I)cc(I)c1O)c1cc(C)c(cc1Cl)C(C#N)c1ccc(Cl)cc1
Show InChI InChI=1S/C23H16Cl2I2N2O2/c1-12-7-21(29(2)23(31)17-8-15(26)9-20(27)22(17)30)19(25)10-16(12)18(11-28)13-3-5-14(24)6-4-13/h3-10,18,30H,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215973
PNG
(CHEMBL294403)
Show SMILES Oc1c(Cl)cc(Cl)cc1\C=C\c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C14H8Cl4O/c15-10-6-9(14(19)13(18)7-10)3-1-8-2-4-11(16)12(17)5-8/h1-7,19H/b3-1+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215969
PNG
(CHEMBL57924)
Show SMILES COc1c(I)cc(I)cc1C(=O)Nc1cc(C)c(cc1Cl)C(C#N)c1ccc(Cl)cc1
Show InChI InChI=1S/C23H16Cl2I2N2O2/c1-12-7-21(29-23(30)17-8-15(26)9-20(27)22(17)31-2)19(25)10-16(12)18(11-28)13-3-5-14(24)6-4-13/h3-10,18H,1-2H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215966
PNG
(CHEMBL301903)
Show SMILES Oc1c(Cl)cc(Cl)cc1C(=O)NCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C14H9Cl4NO2/c15-8-4-9(13(20)12(18)5-8)14(21)19-6-7-1-2-10(16)11(17)3-7/h1-5,20H,6H2,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215965
PNG
(CHEMBL57828)
Show SMILES Oc1c(Cl)cc(Cl)cc1NC(=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H7Cl4NO2/c14-7-4-10(17)12(19)11(5-7)18-13(20)6-1-2-8(15)9(16)3-6/h1-5,19H,(H,18,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair
Sporulation kinase A


(Bacillus subtilis (strain 168))		BDBM50215964
PNG
(CHEMBL293285)
Show SMILES Clc1cc(Cl)cc(c1)C(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H7Cl4NO/c14-8-3-7(4-9(15)5-8)13(19)18-10-1-2-11(16)12(17)6-10/h1-6H,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F)

Bioorg Med Chem Lett 8: 1923-8 (1998)


BindingDB Entry DOI: 10.7270/Q27S7QZM
More data for this
Ligand-Target Pair