Compile Data Set for Download or QSAR

Found 814 hits with Last Name = 'courter' and Initial = 'jr'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM111786 (US10112950, Example 72 | US10556908, Example 72 | ...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3ccc(CO)c(C)c3)n3ccnc23)C1 |r| Show InChI InChI=1S/C28H29N5O2/c1-19-14-23(9-10-24(19)17-34)26-25(22-7-5-20(15-29)6-8-22)31-28(27-30-11-13-33(26)27)35-18-21-4-3-12-32(2)16-21/h5-11,13-14,21,34H,3-4,12,16-18H2,1-2H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM111793 (US10112950, Example 73 | US10556908, Example 73 | ...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3ccc4CCC(O)c4c3)n3ccnc23)C1 |r| Show InChI InChI=1S/C29H29N5O2/c1-33-13-2-3-20(17-33)18-36-29-28-31-12-14-34(28)27(23-9-8-21-10-11-25(35)24(21)15-23)26(32-29)22-6-4-19(16-30)5-7-22/h4-9,12,14-15,20,25,35H,2-3,10-11,13,17-18H2,1H3/t20-,25?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM111798 (US10112950, Example 76 | US10556908, Example 76 | ...) Show SMILES COC(=O)N(C)c1cc(ccc1C)-c1c(nc(OC[C@@H]2CCCN(C)C2)c2nccn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C30H32N6O3/c1-20-7-10-24(16-25(20)35(3)30(37)38-4)27-26(23-11-8-21(17-31)9-12-23)33-29(28-32-13-15-36(27)28)39-19-22-6-5-14-34(2)18-22/h7-13,15-16,22H,5-6,14,18-19H2,1-4H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM111800 (US10112950, Example 78 | US10556908, Example 78 | ...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3ccc4CC(O)Cc4c3)n3ccnc23)C1 |r| Show InChI InChI=1S/C29H29N5O2/c1-33-11-2-3-20(17-33)18-36-29-28-31-10-12-34(28)27(23-9-8-22-14-25(35)15-24(22)13-23)26(32-29)21-6-4-19(16-30)5-7-21/h4-10,12-13,20,25,35H,2-3,11,14-15,17-18H2,1H3/t20-,25?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM111800 (US10112950, Example 78 | US10556908, Example 78 | ...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3ccc4CC(O)Cc4c3)n3ccnc23)C1 |r| Show InChI InChI=1S/C29H29N5O2/c1-33-11-2-3-20(17-33)18-36-29-28-31-10-12-34(28)27(23-9-8-22-14-25(35)15-24(22)13-23)26(32-29)21-6-4-19(16-30)5-7-21/h4-10,12-13,20,25,35H,2-3,11,14-15,17-18H2,1H3/t20-,25?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM111801 (US10556908, Example 79 | US9695180, 79) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3cc4C(O)CCc4c(F)c3)n3ccnc23)C1 |r| Show InChI InChI=1S/C29H28FN5O2/c1-34-11-2-3-19(16-34)17-37-29-28-32-10-12-35(28)27(26(33-29)20-6-4-18(15-31)5-7-20)21-13-23-22(24(30)14-21)8-9-25(23)36/h4-7,10,12-14,19,25,36H,2-3,8-9,11,16-17H2,1H3/t19-,25?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM111802 (US10112950, Example 80 | US10556908, Example 80 | ...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3ccc4C(O)CCc4c3)n3ccnc23)C1 |r| Show InChI InChI=1S/C29H29N5O2/c1-33-13-2-3-20(17-33)18-36-29-28-31-12-14-34(28)27(23-8-10-24-22(15-23)9-11-25(24)35)26(32-29)21-6-4-19(16-30)5-7-21/h4-8,10,12,14-15,20,25,35H,2-3,9,11,13,17-18H2,1H3/t20-,25?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM111803 (US10112950, Example 81 | US10556908, Example 81 | ...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3cc(C)c(CO)c(F)c3)n3ccnc23)C1 |r| Show InChI InChI=1S/C28H28FN5O2/c1-18-12-22(13-24(29)23(18)16-35)26-25(21-7-5-19(14-30)6-8-21)32-28(27-31-9-11-34(26)27)36-17-20-4-3-10-33(2)15-20/h5-9,11-13,20,35H,3-4,10,15-17H2,1-2H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112389 (US10112950, Example 85 | US10556908, Example 85 | ...) Show SMILES COC(=O)N(C)Cc1ccc(cc1F)-c1c(nc(OC[C@@H]2CCCN(C)C2)c2nccn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C30H31FN6O3/c1-35-13-4-5-21(17-35)19-40-29-28-33-12-14-37(28)27(26(34-29)22-8-6-20(16-32)7-9-22)23-10-11-24(25(31)15-23)18-36(2)30(38)39-3/h6-12,14-15,21H,4-5,13,17-19H2,1-3H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112391 (US10112950, Example 87 | US10556908, Example 87 | ...) Show SMILES CC(O)c1cc(ccc1C)-c1c(nc(OC[C@@H]2CCCN(C)C2)c2nccn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C29H31N5O2/c1-19-6-9-24(15-25(19)20(2)35)27-26(23-10-7-21(16-30)8-11-23)32-29(28-31-12-14-34(27)28)36-18-22-5-4-13-33(3)17-22/h6-12,14-15,20,22,35H,4-5,13,17-18H2,1-3H3/t20?,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112394 (US10112950, Example 88 | US10556908, Example 88 | ...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3cc4CCC(O)c4c(F)c3)n3ccnc23)C1 |r| Show InChI InChI=1S/C29H28FN5O2/c1-34-11-2-3-19(16-34)17-37-29-28-32-10-12-35(28)27(26(33-29)20-6-4-18(15-31)5-7-20)22-13-21-8-9-24(36)25(21)23(30)14-22/h4-7,10,12-14,19,24,36H,2-3,8-9,11,16-17H2,1H3/t19-,24?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112399 (US10112950, Example 90 | US10556908, Example 90 | ...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3ccc(C)cc3CO)n3ccnc23)C1 |r,wD:5.5,(8.67,1.15,;7.34,1.93,;7.34,3.47,;6,4.23,;4.67,3.47,;4.67,1.93,;3.33,1.15,;2,1.93,;.67,1.15,;-.67,1.93,;-2,1.15,;-3.33,1.93,;-3.33,3.47,;-4.67,4.23,;-6.05,3.49,;-6,1.93,;-4.67,1.15,;-7.38,4.26,;-8.72,5.03,;-2,-.38,;-3.33,-1.15,;-4.67,-.38,;-6,-1.15,;-6,-2.69,;-7.34,-3.47,;-4.67,-3.47,;-3.33,-2.69,;-2,-3.47,;-2,-5,;-.67,-1.15,;-.35,-2.66,;1.18,-2.82,;1.81,-1.42,;.67,-.38,;6,1.15,)| Show InChI InChI=1S/C28H29N5O2/c1-19-5-10-24(23(14-19)17-34)26-25(22-8-6-20(15-29)7-9-22)31-28(27-30-11-13-33(26)27)35-18-21-4-3-12-32(2)16-21/h5-11,13-14,21,34H,3-4,12,16-18H2,1-2H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112400 (US10112950, Example 91 | US10556908, Example 91 | ...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3ccc(C)c(CC#N)c3)n3ccnc23)C1 |r| Show InChI InChI=1S/C29H28N6O/c1-20-5-8-25(16-24(20)11-12-30)27-26(23-9-6-21(17-31)7-10-23)33-29(28-32-13-15-35(27)28)36-19-22-4-3-14-34(2)18-22/h5-10,13,15-16,22H,3-4,11,14,18-19H2,1-2H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112405 (US10112950, Example 92 | US10556908, Example 92 | ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc(C)c(C)c2)n2ccnc12 Show InChI InChI=1S/C27H29N7/c1-18-15-22(17-30-19(18)2)25-24(21-7-5-20(16-28)6-8-21)31-27(26-29-11-14-34(25)26)33-12-9-23(10-13-33)32(3)4/h5-8,11,14-15,17,23H,9-10,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112406 (US10112950, Example 93 | US10556908, Example 93 | ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3CC(O)Cc3c2)n2ccnc12 Show InChI InChI=1S/C29H30N6O/c1-33(2)24-9-12-34(13-10-24)29-28-31-11-14-35(28)27(22-8-7-21-16-25(36)17-23(21)15-22)26(32-29)20-5-3-19(18-30)4-6-20/h3-8,11,14-15,24-25,36H,9-10,12-13,16-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112407 (US10556908, Example 94 | US9695180, 94) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc(C)c(O)c2)n2ccnc12 Show InChI InChI=1S/C26H27N7O/c1-17-22(34)14-20(16-29-17)24-23(19-6-4-18(15-27)5-7-19)30-26(25-28-10-13-33(24)25)32-11-8-21(9-12-32)31(2)3/h4-7,10,13-14,16,21,34H,8-9,11-12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112412 (US10556908, Example 95 | US9695180, 95) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3CCC(O)c3c2)n2ccnc12 Show InChI InChI=1S/C29H30N6O/c1-33(2)23-11-14-34(15-12-23)29-28-31-13-16-35(28)27(22-8-7-20-9-10-25(36)24(20)17-22)26(32-29)21-5-3-19(18-30)4-6-21/h3-8,13,16-17,23,25,36H,9-12,14-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112416 (US10556908, Example 96 | US9695180, 96) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(C)c(CO)c2)n2ccnc12 Show InChI InChI=1S/C28H30N6O/c1-19-4-7-22(16-23(19)18-35)26-25(21-8-5-20(17-29)6-9-21)31-28(27-30-12-15-34(26)27)33-13-10-24(11-14-33)32(2)3/h4-9,12,15-16,24,35H,10-11,13-14,18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112417 (US10112950, Example 97 | US10556908, Example 97 | ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cc(C)c(CO)c(F)c2)n2ccnc12 Show InChI InChI=1S/C28H29FN6O/c1-18-14-21(15-24(29)23(18)17-36)26-25(20-6-4-19(16-30)5-7-20)32-28(27-31-10-13-35(26)27)34-11-8-22(9-12-34)33(2)3/h4-7,10,13-15,22,36H,8-9,11-12,17H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112422 (US10112950, Example 98 | US10556908, Example 98 | ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3N(C)C(=O)Cc3c2)n2ccnc12 Show InChI InChI=1S/C29H29N7O/c1-33(2)23-10-13-35(14-11-23)29-28-31-12-15-36(28)27(26(32-29)20-6-4-19(18-30)5-7-20)21-8-9-24-22(16-21)17-25(37)34(24)3/h4-9,12,15-16,23H,10-11,13-14,17H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112423 (US10112950, Example 99 | US10556908, Example 99 | ...) Show SMILES CN(C)C1CCCN(C1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(nc2)N2CCCC2=O)n2ccnc12 Show InChI InChI=1S/C29H30N8O/c1-34(2)23-5-3-14-35(19-23)29-28-31-13-16-37(28)27(26(33-29)21-9-7-20(17-30)8-10-21)22-11-12-24(32-18-22)36-15-4-6-25(36)38/h7-13,16,18,23H,3-6,14-15,19H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112424 (US10112950, Example 100 | US10556908, Example 100 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(nc2)N2CCN(C)C2=O)n2ccnc12 Show InChI InChI=1S/C29H31N9O/c1-34(2)23-10-13-36(14-11-23)28-27-31-12-15-38(27)26(25(33-28)21-6-4-20(18-30)5-7-21)22-8-9-24(32-19-22)37-17-16-35(3)29(37)39/h4-9,12,15,19,23H,10-11,13-14,16-17H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112452 (US10112950, Example 101 | US10556908, Example 101 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3nccnc3c2)n2ccnc12 Show InChI InChI=1S/C28H26N8/c1-34(2)22-9-14-35(15-10-22)28-27-32-13-16-36(27)26(21-7-8-23-24(17-21)31-12-11-30-23)25(33-28)20-5-3-19(18-29)4-6-20/h3-8,11-13,16-17,22H,9-10,14-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112453 (US10112950, Example 102 | US10556908, Example 102 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3N(C)C(=O)CCc3c2)n2ccnc12 Show InChI InChI=1S/C30H31N7O/c1-34(2)24-12-15-36(16-13-24)30-29-32-14-17-37(29)28(27(33-30)21-6-4-20(19-31)5-7-21)23-8-10-25-22(18-23)9-11-26(38)35(25)3/h4-8,10,14,17-18,24H,9,11-13,15-16H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112480 (US10112950, Example 103 | US10556908, Example 103 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc3n(C)c(CO)cc3c2)n2ccnc12 Show InChI InChI=1S/C29H30N8O/c1-34(2)23-8-11-36(12-9-23)29-28-31-10-13-37(28)26(25(33-29)20-6-4-19(16-30)5-7-20)22-14-21-15-24(18-38)35(3)27(21)32-17-22/h4-7,10,13-15,17,23,38H,8-9,11-12,18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112485 (US10112950, Example 105 | US10556908, Example 105 ...) Show SMILES CCn1c2ncc(cc2oc1=O)-c1c(nc(N2CCC(CC2)N(C)C)c2nccn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C28H28N8O2/c1-4-35-25-22(38-28(35)37)15-20(17-31-25)24-23(19-7-5-18(16-29)6-8-19)32-27(26-30-11-14-36(24)26)34-12-9-21(10-13-34)33(2)3/h5-8,11,14-15,17,21H,4,9-10,12-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112486 (US10112950, Example 106 | US10556908, Example 106 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3n(C)cnc3c2)n2ccnc12 Show InChI InChI=1S/C28H28N8/c1-33(2)22-10-13-35(14-11-22)28-27-30-12-15-36(27)26(21-8-9-24-23(16-21)31-18-34(24)3)25(32-28)20-6-4-19(17-29)5-7-20/h4-9,12,15-16,18,22H,10-11,13-14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112487 (US10112950, Example 107 | US10556908, Example 107 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc3N(C)C(=O)COc3c2)n2ccnc12 Show InChI InChI=1S/C28H28N8O2/c1-33(2)21-8-11-35(12-9-21)28-27-30-10-13-36(27)25(24(32-28)19-6-4-18(15-29)5-7-19)20-14-22-26(31-16-20)34(3)23(37)17-38-22/h4-7,10,13-14,16,21H,8-9,11-12,17H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112490 (US10112950, Example 109 | US10556908, Example 109 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(nc2)N2CCN(C)C(=O)C2)n2ccnc12 Show InChI InChI=1S/C30H33N9O/c1-35(2)24-10-13-37(14-11-24)30-29-32-12-15-39(29)28(27(34-30)22-6-4-21(18-31)5-7-22)23-8-9-25(33-19-23)38-17-16-36(3)26(40)20-38/h4-9,12,15,19,24H,10-11,13-14,16-17,20H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112491 (US10112950, Example 110 | US10556908, Example 110 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3n(C)nc(CO)c3c2)n2ccnc12 Show InChI InChI=1S/C29H30N8O/c1-34(2)22-10-13-36(14-11-22)29-28-31-12-15-37(28)27(26(32-29)20-6-4-19(17-30)5-7-20)21-8-9-25-23(16-21)24(18-38)33-35(25)3/h4-9,12,15-16,22,38H,10-11,13-14,18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112492 (US10112950, Example 111 | US10556908, Example 111 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc3N(C)C(=O)Cc3c2)n2ccnc12 Show InChI InChI=1S/C28H28N8O/c1-33(2)22-8-11-35(12-9-22)28-27-30-10-13-36(27)25(24(32-28)19-6-4-18(16-29)5-7-19)21-14-20-15-23(37)34(3)26(20)31-17-21/h4-7,10,13-14,17,22H,8-9,11-12,15H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112493 (US10112950, Example 112 | US10556908, Example 112 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc3n(C)ccc3c2)n2ccnc12 Show InChI InChI=1S/C28H28N8/c1-33(2)23-9-13-35(14-10-23)28-27-30-11-15-36(27)25(22-16-21-8-12-34(3)26(21)31-18-22)24(32-28)20-6-4-19(17-29)5-7-20/h4-8,11-12,15-16,18,23H,9-10,13-14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112494 (US10112950, Example 113 | US10556908, Example 113 ...) Show SMILES C[C@@H](O)c1nc2cc(ccc2n1C)-c1c(nc(N2CCC(CC2)N(C)C)c2nccn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C30H32N8O/c1-19(39)28-33-24-17-22(9-10-25(24)36(28)4)27-26(21-7-5-20(18-31)6-8-21)34-30(29-32-13-16-38(27)29)37-14-11-23(12-15-37)35(2)3/h5-10,13,16-17,19,23,39H,11-12,14-15H2,1-4H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112644 (US10112950, Example 115 | US10556908, Example 115 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3n(C)c(C)nc3c2)n2ccnc12 Show InChI InChI=1S/C29H30N8/c1-19-32-24-17-22(9-10-25(24)35(19)4)27-26(21-7-5-20(18-30)6-8-21)33-29(28-31-13-16-37(27)28)36-14-11-23(12-15-36)34(2)3/h5-10,13,16-17,23H,11-12,14-15H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112649 (US10112950, Example 118 | US10556908, Example 118 ...) Show SMILES COc1ncc(cc1O)-c1c(nc(N2CCC(CC2)N(C)C)c2nccn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C26H27N7O2/c1-31(2)20-8-11-32(12-9-20)25-24-28-10-13-33(24)23(19-14-21(34)26(35-3)29-16-19)22(30-25)18-6-4-17(15-27)5-7-18/h4-7,10,13-14,16,20,34H,8-9,11-12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112650 (US10112950, Example 119 | US10556908, Example 119 ...) Show SMILES COc1ncc(cc1O)-c1c(nc(OC[C@@H]2CCCN(C)C2)c2nccn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C26H26N6O3/c1-31-10-3-4-18(15-31)16-35-26-24-28-9-11-32(24)23(20-12-21(33)25(34-2)29-14-20)22(30-26)19-7-5-17(13-27)6-8-19/h5-9,11-12,14,18,33H,3-4,10,15-16H2,1-2H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10556908 (2020) BindingDB Entry DOI: 10.7270/Q2FT8PDM
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM111185 (US10112950, Example 37 | US10556908, Example 37 | ...) Show SMILES CNC(=O)c1cn2c(-c3ccc(C)cc3)c(nc(OC[C@@H]3CCNC3)c2n1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C27H26N6O2/c1-17-3-7-21(8-4-17)24-23(20-9-5-18(13-28)6-10-20)32-27(35-16-19-11-12-30-14-19)25-31-22(15-33(24)25)26(34)29-2/h3-10,15,19,30H,11-12,14,16H2,1-2H3,(H,29,34)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112400 (US10112950, Example 91 | US10556908, Example 91 | ...) Show SMILES CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3ccc(C)c(CC#N)c3)n3ccnc23)C1 |r| Show InChI InChI=1S/C29H28N6O/c1-20-5-8-25(16-24(20)11-12-30)27-26(23-9-6-21(17-31)7-10-23)33-29(28-32-13-15-35(27)28)36-19-22-4-3-14-34(2)18-22/h5-10,13,15-16,22H,3-4,11,14,18-19H2,1-2H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112405 (US10112950, Example 92 | US10556908, Example 92 | ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc(C)c(C)c2)n2ccnc12 Show InChI InChI=1S/C27H29N7/c1-18-15-22(17-30-19(18)2)25-24(21-7-5-20(16-28)6-8-21)31-27(26-29-11-14-34(25)26)33-12-9-23(10-13-33)32(3)4/h5-8,11,14-15,17,23H,9-10,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112406 (US10112950, Example 93 | US10556908, Example 93 | ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3CC(O)Cc3c2)n2ccnc12 Show InChI InChI=1S/C29H30N6O/c1-33(2)24-9-12-34(13-10-24)29-28-31-11-14-35(28)27(22-8-7-21-16-25(36)17-23(21)15-22)26(32-29)20-5-3-19(18-30)4-6-20/h3-8,11,14-15,24-25,36H,9-10,12-13,16-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM296960 ( 4-[8-[4-(dimethylamino)piperidin-1-yl]-5-(3-hydro...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc3CCC(O)c3c2)n2ccnc12 Show InChI InChI=1S/C28H29N7O/c1-33(2)21-9-12-34(13-10-21)28-27-30-11-14-35(27)26(20-15-22-23(31-17-20)7-8-24(22)36)25(32-28)19-5-3-18(16-29)4-6-19/h3-6,11,14-15,17,21,24,36H,7-10,12-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112417 (US10112950, Example 97 | US10556908, Example 97 | ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cc(C)c(CO)c(F)c2)n2ccnc12 Show InChI InChI=1S/C28H29FN6O/c1-18-14-21(15-24(29)23(18)17-36)26-25(20-6-4-19(16-30)5-7-20)32-28(27-31-10-13-35(26)27)34-11-8-22(9-12-34)33(2)3/h4-7,10,13-15,22,36H,8-9,11-12,17H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112422 (US10112950, Example 98 | US10556908, Example 98 | ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3N(C)C(=O)Cc3c2)n2ccnc12 Show InChI InChI=1S/C29H29N7O/c1-33(2)23-10-13-35(14-11-23)29-28-31-12-15-36(28)27(26(32-29)20-6-4-19(18-30)5-7-20)21-8-9-24-22(16-21)17-25(37)34(24)3/h4-9,12,15-16,23H,10-11,13-14,17H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112423 (US10112950, Example 99 | US10556908, Example 99 | ...) Show SMILES CN(C)C1CCCN(C1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(nc2)N2CCCC2=O)n2ccnc12 Show InChI InChI=1S/C29H30N8O/c1-34(2)23-5-3-14-35(19-23)29-28-31-13-16-37(28)27(26(33-29)21-9-7-20(17-30)8-10-21)22-11-12-24(32-18-22)36-15-4-6-25(36)38/h7-13,16,18,23H,3-6,14-15,19H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112424 (US10112950, Example 100 | US10556908, Example 100 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(nc2)N2CCN(C)C2=O)n2ccnc12 Show InChI InChI=1S/C29H31N9O/c1-34(2)23-10-13-36(14-11-23)28-27-31-12-15-38(27)26(25(33-28)21-6-4-20(18-30)5-7-21)22-8-9-24(32-19-22)37-17-16-35(3)29(37)39/h4-9,12,15,19,23H,10-11,13-14,16-17H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112452 (US10112950, Example 101 | US10556908, Example 101 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3nccnc3c2)n2ccnc12 Show InChI InChI=1S/C28H26N8/c1-34(2)22-9-14-35(15-10-22)28-27-32-13-16-36(27)26(21-7-8-23-24(17-21)31-12-11-30-23)25(33-28)20-5-3-19(18-29)4-6-20/h3-8,11-13,16-17,22H,9-10,14-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112453 (US10112950, Example 102 | US10556908, Example 102 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3N(C)C(=O)CCc3c2)n2ccnc12 Show InChI InChI=1S/C30H31N7O/c1-34(2)24-12-15-36(16-13-24)30-29-32-14-17-37(29)28(27(33-30)21-6-4-20(19-31)5-7-21)23-8-10-25-22(18-23)9-11-26(38)35(25)3/h4-8,10,14,17-18,24H,9,11-13,15-16H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112480 (US10112950, Example 103 | US10556908, Example 103 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc3n(C)c(CO)cc3c2)n2ccnc12 Show InChI InChI=1S/C29H30N8O/c1-34(2)23-8-11-36(12-9-23)29-28-31-10-13-37(28)26(25(33-29)20-6-4-19(16-30)5-7-20)22-14-21-15-24(18-38)35(3)27(21)32-17-22/h4-7,10,13-15,17,23,38H,8-9,11-12,18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112485 (US10112950, Example 105 | US10556908, Example 105 ...) Show SMILES CCn1c2ncc(cc2oc1=O)-c1c(nc(N2CCC(CC2)N(C)C)c2nccn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C28H28N8O2/c1-4-35-25-22(38-28(35)37)15-20(17-31-25)24-23(19-7-5-18(16-29)6-8-19)32-27(26-30-11-14-36(24)26)34-12-9-21(10-13-34)33(2)3/h5-8,11,14-15,17,21H,4,9-10,12-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM112486 (US10112950, Example 106 | US10556908, Example 106 ...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3n(C)cnc3c2)n2ccnc12 Show InChI InChI=1S/C28H28N8/c1-33(2)22-10-13-35(14-11-22)28-27-30-12-15-36(27)26(21-8-9-24-23(16-21)31-18-34(24)3)25(32-28)20-6-4-19(17-29)5-7-20/h4-9,12,15-16,18,22H,10-11,13-14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10112950 (2018) BindingDB Entry DOI: 10.7270/Q2HT2RCB
					More data for this Ligand-Target Pair

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