Compile Data Set for Download or QSAR

Found 29 hits with Last Name = 'kimura' and Initial = 'ki'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O |r| Show InChI InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O |r| Show InChI InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prolyl oligopeptidase family protein (Flavobacterium psychrophilum (strain JIP02/86 / AT...)	BDBM50455076 (CHEMBL4214751) Show SMILES CC(=O)Oc1c(OC(C)=O)c2c3cc(O)c(O)cc3oc2c2oc3cc(O)c(O)cc3c12 Show InChI InChI=1S/C22H14O10/c1-7(23)29-19-17-9-3-11(25)13(27)5-15(9)31-21(17)22-18(20(19)30-8(2)24)10-4-12(26)14(28)6-16(10)32-22/h3-6,25-28H,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN CSRS Curated by ChEMBL					Assay Description Inhibition of Flavobacterium POP preincubated for 5 mins followed by Z-Gly-Pro-pNA substrate measured after 30 mins				Bioorg Med Chem Lett 28: 930-933 (2018) Article DOI: 10.1016/j.bmcl.2018.01.054 BindingDB Entry DOI: 10.7270/Q26M39DX
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50455075 (CHEMBL4209844) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CC(=O)NCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCC[C@H]2C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI InChI=1S/C113H142N26O27/c1-6-61(4)95(108(161)135-87(58-140)111(164)139-41-19-30-89(139)112(165)166)136-105(158)80(44-64-22-11-8-12-23-64)134-109(162)96(62(5)141)137-106(159)83(49-69-54-116-59-123-69)124-92(146)57-121-91(145)55-122-97(150)78(43-63-20-9-7-10-21-63)128-99(152)77(42-60(2)3)127-103(156)84-50-90(144)120-56-93(147)125-86(46-66-33-37-71(143)38-34-66)110(163)138-40-18-29-88(138)107(160)133-82(48-68-53-119-75-27-16-14-25-73(68)75)102(155)130-81(47-67-52-118-74-26-15-13-24-72(67)74)101(154)132-85(51-94(148)149)104(157)129-79(45-65-31-35-70(142)36-32-65)100(153)126-76(98(151)131-84)28-17-39-117-113(114)115/h7-16,20-27,31-38,52-54,59-62,76-89,95-96,118-119,140-143H,6,17-19,28-30,39-51,55-58H2,1-5H3,(H,116,123)(H,120,144)(H,121,145)(H,122,150)(H,124,146)(H,125,147)(H,126,153)(H,127,156)(H,128,152)(H,129,157)(H,130,155)(H,131,151)(H,132,154)(H,133,160)(H,134,162)(H,135,161)(H,136,158)(H,137,159)(H,148,149)(H,165,166)(H4,114,115,117)/t61-,62+,76-,77-,78-,79-,80-,81-,82+,83-,84-,85-,86-,87-,88-,89-,95-,96-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN CSRS Curated by ChEMBL					Assay Description Inhibition of prolyl oligopeptidase (unknown origin)				Bioorg Med Chem Lett 28: 930-933 (2018) Article DOI: 10.1016/j.bmcl.2018.01.054 BindingDB Entry DOI: 10.7270/Q26M39DX
					More data for this Ligand-Target Pair
Prolyl oligopeptidase family protein (Flavobacterium psychrophilum (strain JIP02/86 / AT...)	BDBM50269566 (CHEMBL458248 | polyozellin) Show SMILES CC(=O)Oc1c2oc3cc(O)c(O)cc3c2c(OC(C)=O)c2oc3cc(O)c(O)cc3c12 Show InChI InChI=1S/C22H14O10/c1-7(23)29-19-17-9-3-11(25)13(27)5-15(9)32-22(17)20(30-8(2)24)18-10-4-12(26)14(28)6-16(10)31-21(18)19/h3-6,25-28H,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN CSRS Curated by ChEMBL					Assay Description Inhibition of Flavobacterium POP preincubated for 5 mins followed by Z-Gly-Pro-pNA substrate measured after 30 mins				Bioorg Med Chem Lett 28: 930-933 (2018) Article DOI: 10.1016/j.bmcl.2018.01.054 BindingDB Entry DOI: 10.7270/Q26M39DX
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O |r| Show InChI InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50269566 (CHEMBL458248 | polyozellin) Show SMILES CC(=O)Oc1c2oc3cc(O)c(O)cc3c2c(OC(C)=O)c2oc3cc(O)c(O)cc3c12 Show InChI InChI=1S/C22H14O10/c1-7(23)29-19-17-9-3-11(25)13(27)5-15(9)32-22(17)20(30-8(2)24)18-10-4-12(26)14(28)6-16(10)31-21(18)19/h3-6,25-28H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN CSRS Curated by ChEMBL					Assay Description Inhibition of prolyl oligopeptidase (unknown origin)				Bioorg Med Chem Lett 28: 930-933 (2018) Article DOI: 10.1016/j.bmcl.2018.01.054 BindingDB Entry DOI: 10.7270/Q26M39DX
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50529337 (CHEMBL4461655) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(COC(=O)C[C@H](C)O)C2=O |r,t:26| Show InChI InChI=1S/C26H36O7/c1-14-6-7-18-24(3,4)19(28)8-9-25(18,5)17(14)12-26-20(29)11-16(22(31)23(26)33-26)13-32-21(30)10-15(2)27/h11,15,17-19,23,27-28H,1,6-10,12-13H2,2-5H3/t15-,17-,18-,19+,23-,25+,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50529333 (CHEMBL4446535) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(COC(=O)[C@H](O)[C@H](C)O)C2=O |r,t:26| Show InChI InChI=1S/C26H36O8/c1-13-6-7-17-24(3,4)18(28)8-9-25(17,5)16(13)11-26-19(29)10-15(21(31)22(26)34-26)12-33-23(32)20(30)14(2)27/h10,14,16-18,20,22,27-28,30H,1,6-9,11-12H2,2-5H3/t14-,16-,17-,18+,20+,22-,25+,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50529337 (CHEMBL4461655) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(COC(=O)C[C@H](C)O)C2=O |r,t:26| Show InChI InChI=1S/C26H36O7/c1-14-6-7-18-24(3,4)19(28)8-9-25(18,5)17(14)12-26-20(29)11-16(22(31)23(26)33-26)13-32-21(30)10-15(2)27/h11,15,17-19,23,27-28H,1,6-10,12-13H2,2-5H3/t15-,17-,18-,19+,23-,25+,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50529333 (CHEMBL4446535) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(COC(=O)[C@H](O)[C@H](C)O)C2=O |r,t:26| Show InChI InChI=1S/C26H36O8/c1-13-6-7-17-24(3,4)18(28)8-9-25(17,5)16(13)11-26-19(29)10-15(21(31)22(26)34-26)12-33-23(32)20(30)14(2)27/h10,14,16-18,20,22,27-28,30H,1,6-9,11-12H2,2-5H3/t14-,16-,17-,18+,20+,22-,25+,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50270495 (CHEMBL4126890) Show SMILES [H][C@@]12CCC(=C)[C@H](CC3=C(O)C(=O)C4=C(C3=O)[C@@]35C=C[C@@H](O)[C@H](O)[C@]3(C4)C(=O)c3c(O)cc(C)cc3C5=O)[C@@]1(C)CC[C@@H](O)C2(C)C |r,c:8,13,19| Show InChI InChI=1S/C37H40O9/c1-16-12-18-26(23(39)13-16)33(46)37-15-20-27(36(37,31(18)44)11-8-22(38)32(37)45)28(41)19(29(42)30(20)43)14-21-17(2)6-7-24-34(3,4)25(40)9-10-35(21,24)5/h8,11-13,21-22,24-25,32,38-40,42,45H,2,6-7,9-10,14-15H2,1,3-5H3/t21-,22+,24-,25+,32-,35+,36+,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hirosaki University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte 20s proteasome caspase-like activity using Z-LLE-MCA as substrate pretreated for 10 mins followed by substrate additi...				J Nat Prod 80: 1484-1492 (2017) Article DOI: 10.1021/acs.jnatprod.6b01177 BindingDB Entry DOI: 10.7270/Q2S18506
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50529336 (CHEMBL4586314) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(CO)C2=O |r,t:26| Show InChI InChI=1S/C22H30O5/c1-12-5-6-15-20(2,3)16(24)7-8-21(15,4)14(12)10-22-17(25)9-13(11-23)18(26)19(22)27-22/h9,14-16,19,23-24H,1,5-8,10-11H2,2-4H3/t14-,15-,16+,19-,21+,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50270495 (CHEMBL4126890) Show SMILES [H][C@@]12CCC(=C)[C@H](CC3=C(O)C(=O)C4=C(C3=O)[C@@]35C=C[C@@H](O)[C@H](O)[C@]3(C4)C(=O)c3c(O)cc(C)cc3C5=O)[C@@]1(C)CC[C@@H](O)C2(C)C |r,c:8,13,19| Show InChI InChI=1S/C37H40O9/c1-16-12-18-26(23(39)13-16)33(46)37-15-20-27(36(37,31(18)44)11-8-22(38)32(37)45)28(41)19(29(42)30(20)43)14-21-17(2)6-7-24-34(3,4)25(40)9-10-35(21,24)5/h8,11-13,21-22,24-25,32,38-40,42,45H,2,6-7,9-10,14-15H2,1,3-5H3/t21-,22+,24-,25+,32-,35+,36+,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hirosaki University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte 20s proteasome chymotrypsin-like activity using Suc-LLVY-MCA as substrate pretreated for 10 mins followed by substrat...				J Nat Prod 80: 1484-1492 (2017) Article DOI: 10.1021/acs.jnatprod.6b01177 BindingDB Entry DOI: 10.7270/Q2S18506
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50529337 (CHEMBL4461655) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(COC(=O)C[C@H](C)O)C2=O |r,t:26| Show InChI InChI=1S/C26H36O7/c1-14-6-7-18-24(3,4)19(28)8-9-25(18,5)17(14)12-26-20(29)11-16(22(31)23(26)33-26)13-32-21(30)10-15(2)27/h11,15,17-19,23,27-28H,1,6-10,12-13H2,2-5H3/t15-,17-,18-,19+,23-,25+,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50529336 (CHEMBL4586314) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(CO)C2=O |r,t:26| Show InChI InChI=1S/C22H30O5/c1-12-5-6-15-20(2,3)16(24)7-8-21(15,4)14(12)10-22-17(25)9-13(11-23)18(26)19(22)27-22/h9,14-16,19,23-24H,1,5-8,10-11H2,2-4H3/t14-,15-,16+,19-,21+,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50529333 (CHEMBL4446535) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(COC(=O)[C@H](O)[C@H](C)O)C2=O |r,t:26| Show InChI InChI=1S/C26H36O8/c1-13-6-7-17-24(3,4)18(28)8-9-25(17,5)16(13)11-26-19(29)10-15(21(31)22(26)34-26)12-33-23(32)20(30)14(2)27/h10,14,16-18,20,22,27-28,30H,1,6-9,11-12H2,2-5H3/t14-,16-,17-,18+,20+,22-,25+,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50529335 (CHEMBL4528868) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(COC(=O)C[C@H](C)O)[C@H]2O |r,t:26| Show InChI InChI=1S/C26H38O7/c1-14-6-7-18-24(3,4)19(28)8-9-25(18,5)17(14)12-26-20(29)11-16(22(31)23(26)33-26)13-32-21(30)10-15(2)27/h11,15,17-19,22-23,27-28,31H,1,6-10,12-13H2,2-5H3/t15-,17-,18-,19+,22+,23-,25+,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50529335 (CHEMBL4528868) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(COC(=O)C[C@H](C)O)[C@H]2O |r,t:26| Show InChI InChI=1S/C26H38O7/c1-14-6-7-18-24(3,4)19(28)8-9-25(18,5)17(14)12-26-20(29)11-16(22(31)23(26)33-26)13-32-21(30)10-15(2)27/h11,15,17-19,22-23,27-28,31H,1,6-10,12-13H2,2-5H3/t15-,17-,18-,19+,22+,23-,25+,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50270495 (CHEMBL4126890) Show SMILES [H][C@@]12CCC(=C)[C@H](CC3=C(O)C(=O)C4=C(C3=O)[C@@]35C=C[C@@H](O)[C@H](O)[C@]3(C4)C(=O)c3c(O)cc(C)cc3C5=O)[C@@]1(C)CC[C@@H](O)C2(C)C |r,c:8,13,19| Show InChI InChI=1S/C37H40O9/c1-16-12-18-26(23(39)13-16)33(46)37-15-20-27(36(37,31(18)44)11-8-22(38)32(37)45)28(41)19(29(42)30(20)43)14-21-17(2)6-7-24-34(3,4)25(40)9-10-35(21,24)5/h8,11-13,21-22,24-25,32,38-40,42,45H,2,6-7,9-10,14-15H2,1,3-5H3/t21-,22+,24-,25+,32-,35+,36+,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hirosaki University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte 20s proteasome trypsin-like activity using Boc-LRR-MCA as substrate pretreated for 10 mins followed by substrate addi...				J Nat Prod 80: 1484-1492 (2017) Article DOI: 10.1021/acs.jnatprod.6b01177 BindingDB Entry DOI: 10.7270/Q2S18506
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50529336 (CHEMBL4586314) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(CO)C2=O |r,t:26| Show InChI InChI=1S/C22H30O5/c1-12-5-6-15-20(2,3)16(24)7-8-21(15,4)14(12)10-22-17(25)9-13(11-23)18(26)19(22)27-22/h9,14-16,19,23-24H,1,5-8,10-11H2,2-4H3/t14-,15-,16+,19-,21+,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50529334 (CHEMBL4458315) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(COC(=O)[C@H](O)[C@H](C)O)[C@H]2O |r,t:26| Show InChI InChI=1S/C26H38O8/c1-13-6-7-17-24(3,4)18(28)8-9-25(17,5)16(13)11-26-19(29)10-15(21(31)22(26)34-26)12-33-23(32)20(30)14(2)27/h10,14,16-18,20-22,27-28,30-31H,1,6-9,11-12H2,2-5H3/t14-,16-,17-,18+,20+,21+,22-,25+,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50529334 (CHEMBL4458315) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(COC(=O)[C@H](O)[C@H](C)O)[C@H]2O |r,t:26| Show InChI InChI=1S/C26H38O8/c1-13-6-7-17-24(3,4)18(28)8-9-25(17,5)16(13)11-26-19(29)10-15(21(31)22(26)34-26)12-33-23(32)20(30)14(2)27/h10,14,16-18,20-22,27-28,30-31H,1,6-9,11-12H2,2-5H3/t14-,16-,17-,18+,20+,21+,22-,25+,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50529332 (CHEMBL4521474) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(CO)[C@H]2O |r,t:26| Show InChI InChI=1S/C22H32O5/c1-12-5-6-15-20(2,3)16(24)7-8-21(15,4)14(12)10-22-17(25)9-13(11-23)18(26)19(22)27-22/h9,14-16,18-19,23-24,26H,1,5-8,10-11H2,2-4H3/t14-,15-,16+,18+,19-,21+,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of beta5 subunit of 20S proteasome in human erythrocytes using Suc-LLVY-MCA as substrate preincubated with e...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50529332 (CHEMBL4521474) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(CO)[C@H]2O |r,t:26| Show InChI InChI=1S/C22H32O5/c1-12-5-6-15-20(2,3)16(24)7-8-21(15,4)14(12)10-22-17(25)9-13(11-23)18(26)19(22)27-22/h9,14-16,18-19,23-24,26H,1,5-8,10-11H2,2-4H3/t14-,15-,16+,18+,19-,21+,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50529335 (CHEMBL4528868) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(COC(=O)C[C@H](C)O)[C@H]2O |r,t:26| Show InChI InChI=1S/C26H38O7/c1-14-6-7-18-24(3,4)19(28)8-9-25(18,5)17(14)12-26-20(29)11-16(22(31)23(26)33-26)13-32-21(30)10-15(2)27/h11,15,17-19,22-23,27-28,31H,1,6-10,12-13H2,2-5H3/t15-,17-,18-,19+,22+,23-,25+,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50529332 (CHEMBL4521474) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(CO)[C@H]2O |r,t:26| Show InChI InChI=1S/C22H32O5/c1-12-5-6-15-20(2,3)16(24)7-8-21(15,4)14(12)10-22-17(25)9-13(11-23)18(26)19(22)27-22/h9,14-16,18-19,23-24,26H,1,5-8,10-11H2,2-4H3/t14-,15-,16+,18+,19-,21+,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of caspase-like activity of beta1 subunit of 20S proteasome in human erythrocytes using Z-LLE-MCA as substrate preincubated with enzyme fo...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50529334 (CHEMBL4458315) Show SMILES [H][C@@]12O[C@]1(C[C@H]1C(=C)CC[C@@]3([H])C(C)(C)[C@H](O)CC[C@]13C)C(=O)C=C(COC(=O)[C@H](O)[C@H](C)O)[C@H]2O |r,t:26| Show InChI InChI=1S/C26H38O8/c1-13-6-7-17-24(3,4)18(28)8-9-25(17,5)16(13)11-26-19(29)10-15(21(31)22(26)34-26)12-33-23(32)20(30)14(2)27/h10,14,16-18,20-22,27-28,30-31H,1,6-9,11-12H2,2-5H3/t14-,16-,17-,18+,20+,21+,22-,25+,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of beta2 subunit of 20S proteasome in human erythrocytes using Boc-LRR-MCA as substrate preincubated with enzyme ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115161 BindingDB Entry DOI: 10.7270/Q29W0JZJ
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50465052 (CHEMBL4288015) Show SMILES [H][C@@]12CCc3cc(C)ccc3[C@@]1(C)CCC[C@]2(C)CO |r| Show InChI InChI=1S/C18H26O/c1-13-5-7-15-14(11-13)6-8-16-17(2,12-19)9-4-10-18(15,16)3/h5,7,11,16,19H,4,6,8-10,12H2,1-3H3/t16-,17+,18+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.78E+5	n/a	n/a	n/a	n/a	n/a	n/a
Iwate University Curated by ChEMBL					Assay Description Inhibition of human GSK-3beta using peptide substrate				J Nat Prod 81: 1070-1074 (2018) Article DOI: 10.1021/acs.jnatprod.7b00922 BindingDB Entry DOI: 10.7270/Q2NG4T9T
					More data for this Ligand-Target Pair