Found 47 hits with Last Name = 'xu' and Initial = 'ky' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50612552
(CHEMBL5275552)Show SMILES Cc1ccc(NC(=O)Cn2cc(cn2)-c2ccc3c(NC(=O)c4ccc(cc4)N4CCNCC4)n[nH]c3c2)cc1C(F)(F)F | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 0.420 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM220447
(US10633379, Compound X | US9296741, 36)Show SMILES CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C22H19F2N3O4S/c1-3-32(29,30)26-14-5-7-19(31-20-6-4-13(23)10-18(20)24)16(11-14)17-12-27(2)22(28)21-15(17)8-9-25-21/h4-12,25-26H,3H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570288
(CHEMBL4878552)Show SMILES Cc1ccc(NC(=O)Cn2cc(cn2)-c2ccc3c(NC(=O)c4cnn(C)c4)n[nH]c3c2)cc1C(F)(F)F | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.730 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570281
(CHEMBL4858003)Show SMILES Cc1ccc(NC(=O)Cn2cc(cn2)-c2ccc3c(NC(=O)C4CC4)n[nH]c3c2)cc1C(F)(F)F | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570283
(CHEMBL4870465)Show SMILES CC(=O)Nc1n[nH]c2cc(ccc12)-c1cnn(CC(=O)Nc2ccc(C)c(c2)C(F)(F)F)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570287
(CHEMBL4872941)Show SMILES Cc1ccc(NC(=O)Cn2cc(cn2)-c2ccc3c(NC(=O)c4cccnc4)n[nH]c3c2)cc1C(F)(F)F | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50612551
(CHEMBL5272444)Show SMILES Cc1ccc(NC(=O)Cn2cc(cn2)-c2ccc3c(NC(=O)c4ccc(N)cc4)n[nH]c3c2)cc1C(F)(F)F | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570278
(CHEMBL4853592)Show SMILES Cc1ccc(NC(=O)Cn2cc(cn2)-c2ccc3c(N)n[nH]c3c2)cc1C(F)(F)F | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570277
(CHEMBL4861302)Show SMILES Nc1n[nH]c2cc(ccc12)-c1cnn(CC(=O)Nc2cccc(c2)C(F)(F)F)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570286
(CHEMBL4874982)Show SMILES CN1CCC(CC1)C(=O)Nc1n[nH]c2cc(ccc12)-c1cnn(CC(=O)Nc2ccc(C)c(c2)C(F)(F)F)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570282
(CHEMBL4860732)Show SMILES Fc1c(NC(=O)Cn2cc(cn2)-c2ccc3c(NC(=O)C4CC4)n[nH]c3c2)cccc1C(F)(F)F | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570276
(CHEMBL4879197)Show SMILES Nc1n[nH]c2cc(ccc12)-c1cnn(CC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570293
(CHEMBL4871126)Show SMILES Cc1ccc(NC(=O)Cc2ccc(s2)-c2ccc3c(NC(=O)C4CC4)n[nH]c3c2)cc1C(F)(F)F | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570280
(CHEMBL4846198)Show SMILES FC(F)(F)c1cc(NC(=O)Cn2cc(cn2)-c2ccc3c(NC(=O)C4CC4)n[nH]c3c2)ccc1Cl | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570285
(CHEMBL4861155)Show SMILES Cc1ccc(NC(=O)Cn2cc(cn2)-c2ccc3c(NC(=O)C4CCCC4)n[nH]c3c2)cc1C(F)(F)F | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570279
(CHEMBL4873983)Show SMILES Nc1n[nH]c2cc(ccc12)-c1cnn(CC(=O)Nc2cccc(c2F)C(F)(F)F)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50365262
((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...)Show SMILES Cc1nnc2[C@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14| Show InChI InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid UniChem
Similars
| | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570291
(CHEMBL4866941)Show SMILES Cc1nn(CC(=O)Nc2ccc(C)c(c2)C(F)(F)F)cc1-c1ccc2c(NC(=O)C3CC3)n[nH]c2c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM16673
(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1 Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570284
(CHEMBL4869697)Show SMILES CC(C)C(=O)Nc1n[nH]c2cc(ccc12)-c1cnn(CC(=O)Nc2ccc(C)c(c2)C(F)(F)F)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570289
(CHEMBL4858980)Show SMILES CCNc1n[nH]c2cc(ccc12)-c1cnn(CC(=O)Nc2ccc(C)c(c2)C(F)(F)F)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610315
(CHEMBL5289077)Show SMILES CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1ccc2[nH]c(=O)c(C)nc2c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570290
(CHEMBL4857358)Show SMILES Cc1ccc(NC(=O)Cn2cc(cn2)-c2ccc3c(NCC4CC4)n[nH]c3c2)cc1C(F)(F)F | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610316
(CHEMBL5266305)Show SMILES CC(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1ccc2[nH]c(=O)c(C)nc2c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610331
(CHEMBL5285927)Show SMILES Cc1nc2cc(ccc2[nH]c1=O)-c1cc(NS(C)(=O)=O)ccc1Oc1ccc(F)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570272
(CHEMBL4876592)Show SMILES CS(=O)(=O)Cc1cccc(Nc2n[nH]c3cc(ccc23)-c2cnn(CC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c2)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570274
(CHEMBL4852434)Show SMILES Cn1cc(Nc2n[nH]c3cc(ccc23)-c2cnn(CC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c2)cn1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570273
(CHEMBL4849476)Show SMILES Cn1cc2ccc(Nc3n[nH]c4cc(ccc34)-c3cnn(CC(=O)Nc4ccc(Cl)c(c4)C(F)(F)F)c3)cc2n1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 249 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570292
(CHEMBL4857488)Show SMILES Cc1nn(CC(=O)Nc2ccc(C)c(c2)C(F)(F)F)c(C)c1-c1ccc2c(NC(=O)C3CC3)n[nH]c2c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 307 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610330
(CHEMBL5272457)Show SMILES Cc1nc2cc(ccc2[nH]c1=O)-c1cc(NS(C)(=O)=O)ccc1Oc1ccc(Cl)cc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 341 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610319
(CHEMBL5290271)Show SMILES CC(O)c1ccc(Oc2ccc(F)cc2F)c(c1)-c1ccc2[nH]c(=O)c(C)nc2c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 406 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570275
(CHEMBL4856065)Show SMILES CNS(=O)(=O)c1cc(Nc2n[nH]c3cc(ccc23)-c2cnn(CC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c2)ccc1C | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 407 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610325
(CHEMBL5286474)Show SMILES Cc1nc2cc(ccc2[nH]c1=O)-c1cc(ccc1Oc1ccc(F)cc1F)C(=O)NCCO | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 621 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610321
(CHEMBL5283605)Show SMILES Cc1nc2cc(ccc2[nH]c1=O)-c1cc(CS(C)(=O)=O)ccc1Oc1ccc(F)cc1F | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 753 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610322
(CHEMBL5280436)Show SMILES CCS(=O)(=O)Cc1ccc(Oc2ccc(F)cc2F)c(c1)-c1ccc2[nH]c(=O)c(C)nc2c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 777 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50570271
(CHEMBL4863009)Show SMILES FC(F)(F)c1cc(NC(=O)Cn2cc(cn2)-c2ccc3c(Nc4cccnc4)n[nH]c3c2)ccc1Cl | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 892 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 10 mins followed by kinase substrate addition and measured after 30 mins by caliper mobility shif... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113192 BindingDB Entry DOI: 10.7270/Q2WQ07J0 |
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610320
(CHEMBL5291169)Show SMILES Cc1nc2cc(ccc2[nH]c1=O)-c1cc(ccc1Oc1ccc(F)cc1F)C(C)(C)O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610324
(CHEMBL5266847)Show SMILES CN1CCN(CC1)C(=O)c1ccc(Oc2ccc(F)cc2F)c(c1)-c1ccc2[nH]c(=O)c(C)nc2c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610326
(CHEMBL5287873)Show SMILES Cc1nc2cc(ccc2[nH]c1=O)-c1cc(ccc1Oc1ccc(F)cc1F)C(=O)N1CCOCC1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 1.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610333
(CHEMBL5267895)Show SMILES Cc1nc2cc(ccc2[nH]c1=O)-c1cc(NS(C)(=O)=O)ccc1Oc1ccc(F)cc1Cl | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 1.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610329
(CHEMBL5290197)Show SMILES Cc1ccccc1Oc1ccc(NS(C)(=O)=O)cc1-c1ccc2[nH]c(=O)c(C)nc2c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 2.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610332
(CHEMBL5266283)Show SMILES COc1cc(Cl)ccc1Oc1ccc(NS(C)(=O)=O)cc1-c1ccc2[nH]c(=O)c(C)nc2c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 2.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610318
(CHEMBL5269292)Show SMILES Cc1nc2cc(ccc2[nH]c1=O)-c1cc(C=O)ccc1Oc1ccc(F)cc1F | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610328
(CHEMBL5277224)Show SMILES Cc1nc2cc(ccc2[nH]c1=O)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1C(F)(F)F | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 2.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610327
(CHEMBL5270976)Show SMILES COc1ccccc1Oc1ccc(NS(C)(=O)=O)cc1-c1ccc2[nH]c(=O)c(C)nc2c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 2.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610317
(CHEMBL5269534)Show SMILES Cc1nc2cc(ccc2[nH]c1=O)-c1cc(ccc1Oc1ccc(F)cc1F)S(C)(=O)=O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 3.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Bromodomain-containing protein 4
(Homo sapiens (Human)) | BDBM50610323
(CHEMBL5287461)Show SMILES COC(=O)c1ccc(Oc2ccc(F)cc2F)c(c1)-c1ccc2[nH]c(=O)c(C)nc2c1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 4.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |