Compile Data Set for Download or QSAR

Found 98 hits with Last Name = 'cooymans' and Initial = 'l'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hemagglutinin ()	BDBM611021 (US10626108, Compound 15) Show SMILES Cc1nc(nc(N[C@H]2CCC[C@H](C2)NC(=O)c2cnn[nH]2)c1F)-c1c[nH]c2c(F)cc(F)cc12 |r,$;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3KH8
					More data for this Ligand-Target Pair
Hemagglutinin ()	BDBM611022 (US10626108, Compound 21) Show SMILES Cc1nc(nc(N[C@@H]2CCC[C@@H](C2)NC(=O)c2ccccn2)c1F)-c1c[nH]c2ncncc12 |r,$;;;;;;HN;;;;;;;HN;;;;;;;;;;;;;;;;;;;$| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3KH8
					More data for this Ligand-Target Pair
Hemagglutinin ()	BDBM611015 (US10626108, Compound 13) Show SMILES Cc1nc(nc(N[C@H]2CCC[C@H](C2)NC(=O)c2cn(C)cn2)c1F)-c1c[nH]c2c(F)cc(F)cc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3KH8
					More data for this Ligand-Target Pair
Hemagglutinin ()	BDBM611029 (US10626108, Compound 29) Show SMILES Cc1nc(nc(N[C@H]2CCC[C@H](C2)NC(=O)c2csc(n2)C(O)=O)c1F)-c1c[nH]c2c(F)cc(F)cc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3KH8
					More data for this Ligand-Target Pair
Hemagglutinin ()	BDBM611020 (US10626108, Compound 14) Show SMILES Cc1nc(nc(N[C@H]2CCC[C@H](C2)NC(=O)c2cnn(C)c2)c1F)-c1c[nH]c2c(F)cc(F)cc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3KH8
					More data for this Ligand-Target Pair
Hemagglutinin ()	BDBM611056 (US10626108, Compound 36) Show SMILES OC(=O)c1nc(nc(N[C@@H]2CCC[C@@H](C2)NC(=O)c2cnn[nH]2)c1F)-c1c[nH]c2c(F)cc(F)cc12 |r,$;;;;;;;;HN;;;;;;;HN;;;;;;;;;;;;;;;;;;;;$| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3KH8
					More data for this Ligand-Target Pair
Hemagglutinin ()	BDBM611028 (US10626108, Compound 28) Show SMILES Fc1cc(F)c2[nH]cc(-c3nncc(N[C@@H]4CCC[C@@H](C4)NC(=O)N4CCCC4)n3)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3KH8
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50191064 (CHEMBL3894220) Show SMILES Nc1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 Show InChI InChI=1S/C22H20ClF5N6O/c23-14-2-3-15-13(1-4-17(29)33-15)18(14)19(35)30-11-16(34-7-5-21(24,25)6-8-34)12-9-31-20(32-10-12)22(26,27)28/h1-4,9-10,16H,5-8,11H2,(H2,29,33)(H,30,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor assessed as reduction in calcium flux by FLIPR assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50190913 (CHEMBL3912682) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1c(Cl)ccc2nc(ccc12)N1CCOCC1)N1CCC(F)(F)CC1 Show InChI InChI=1S/C26H26ClF5N6O2/c27-18-2-3-19-17(1-4-21(36-19)38-9-11-40-12-10-38)22(18)23(39)33-15-20(37-7-5-25(28,29)6-8-37)16-13-34-24(35-14-16)26(30,31)32/h1-4,13-14,20H,5-12,15H2,(H,33,39)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor assessed as reduction in calcium flux by FLIPR assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
Hemagglutinin ()	BDBM611026 (US10626108, Compound 25) Show SMILES Fc1cc(F)c2[nH]cc(-c3cncc(N[C@@H]4CCC[C@@H](C4)NC(=O)N4CCCC4)n3)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3KH8
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50190797 (CHEMBL3974590) Show SMILES O[C@@H]1CCN(C1)c1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 |r| Show InChI InChI=1S/C26H26ClF5N6O2/c27-18-2-3-19-17(1-4-21(36-19)38-8-5-16(39)14-38)22(18)23(40)33-13-20(37-9-6-25(28,29)7-10-37)15-11-34-24(35-12-15)26(30,31)32/h1-4,11-12,16,20,39H,5-10,13-14H2,(H,33,40)/t16-,20?/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor assessed as reduction in calcium flux by FLIPR assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50190804 (CHEMBL3966074) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1c(Cl)ccc2nc(NC3CC3)ccc12)N1CCC(F)(F)CC1 Show InChI InChI=1S/C25H24ClF5N6O/c26-17-4-5-18-16(3-6-20(36-18)35-15-1-2-15)21(17)22(38)32-13-19(37-9-7-24(27,28)8-10-37)14-11-33-23(34-12-14)25(29,30)31/h3-6,11-12,15,19H,1-2,7-10,13H2,(H,32,38)(H,35,36)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor assessed as reduction in calcium flux by FLIPR assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50191067 (CHEMBL3963395) Show SMILES OCCNc1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 Show InChI InChI=1S/C24H24ClF5N6O2/c25-16-2-3-17-15(1-4-19(35-17)31-7-10-37)20(16)21(38)32-13-18(36-8-5-23(26,27)6-9-36)14-11-33-22(34-12-14)24(28,29)30/h1-4,11-12,18,37H,5-10,13H2,(H,31,35)(H,32,38)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor assessed as reduction in calcium flux by FLIPR assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Mus musculus)	BDBM50190797 (CHEMBL3974590) Show SMILES O[C@@H]1CCN(C1)c1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 |r| Show InChI InChI=1S/C26H26ClF5N6O2/c27-18-2-3-19-17(1-4-21(36-19)38-8-5-16(39)14-38)22(18)23(40)33-13-20(37-9-6-25(28,29)7-10-37)15-11-34-24(35-12-15)26(30,31)32/h1-4,11-12,16,20,39H,5-10,13-14H2,(H,33,40)/t16-,20?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at mouse P2X7 receptor assessed as reduction in calcium flux by FLIPR calcium flux assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50190917 (CHEMBL3918589) Show SMILES CNc1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 Show InChI InChI=1S/C23H22ClF5N6O/c1-30-18-5-2-14-16(34-18)4-3-15(24)19(14)20(36)31-12-17(35-8-6-22(25,26)7-9-35)13-10-32-21(33-11-13)23(27,28)29/h2-5,10-11,17H,6-9,12H2,1H3,(H,30,34)(H,31,36)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor assessed as reduction in calcium flux by FLIPR assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50191061 (CHEMBL3893653) Show SMILES CN1CCN(CC1)c1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 Show InChI InChI=1S/C27H29ClF5N7O/c1-38-10-12-40(13-11-38)22-5-2-18-20(37-22)4-3-19(28)23(18)24(41)34-16-21(39-8-6-26(29,30)7-9-39)17-14-35-25(36-15-17)27(31,32)33/h2-5,14-15,21H,6-13,16H2,1H3,(H,34,41)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor assessed as reduction in calcium flux by FLIPR assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50190797 (CHEMBL3974590) Show SMILES O[C@@H]1CCN(C1)c1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 |r| Show InChI InChI=1S/C26H26ClF5N6O2/c27-18-2-3-19-17(1-4-21(36-19)38-8-5-16(39)14-38)22(18)23(40)33-13-20(37-9-6-25(28,29)7-10-37)15-11-34-24(35-12-15)26(30,31)32/h1-4,11-12,16,20,39H,5-10,13-14H2,(H,33,40)/t16-,20?/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at P2X7 receptor in human whole blood assessed as reduction in LPS/BzATP-induced IL-1beta release preincubated with LPS-stimulate...				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Mus musculus)	BDBM50190913 (CHEMBL3912682) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1c(Cl)ccc2nc(ccc12)N1CCOCC1)N1CCC(F)(F)CC1 Show InChI InChI=1S/C26H26ClF5N6O2/c27-18-2-3-19-17(1-4-21(36-19)38-9-11-40-12-10-38)22(18)23(39)33-15-20(37-7-5-25(28,29)6-8-37)16-13-34-24(35-14-16)26(30,31)32/h1-4,13-14,20H,5-12,15H2,(H,33,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at mouse P2X7 receptor assessed as reduction in calcium flux by FLIPR calcium flux assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50191063 (CHEMBL3982581) Show SMILES OC1CCN(CC1)c1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 Show InChI InChI=1S/C27H28ClF5N6O2/c28-19-2-3-20-18(1-4-22(37-20)39-9-5-17(40)6-10-39)23(19)24(41)34-15-21(38-11-7-26(29,30)8-12-38)16-13-35-25(36-14-16)27(31,32)33/h1-4,13-14,17,21,40H,5-12,15H2,(H,34,41)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor assessed as reduction in calcium flux by FLIPR assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Mus musculus)	BDBM50190804 (CHEMBL3966074) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1c(Cl)ccc2nc(NC3CC3)ccc12)N1CCC(F)(F)CC1 Show InChI InChI=1S/C25H24ClF5N6O/c26-17-4-5-18-16(3-6-20(36-18)35-15-1-2-15)21(17)22(38)32-13-19(37-9-7-24(27,28)8-10-37)14-11-33-23(34-12-14)25(29,30)31/h3-6,11-12,15,19H,1-2,7-10,13H2,(H,32,38)(H,35,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at mouse P2X7 receptor assessed as reduction in calcium flux by FLIPR calcium flux assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
Hemagglutinin ()	BDBM611014 (US10626108, Compound 6) Show SMILES OC(=O)[C@H]1C2CCC(CC2)[C@@H]1Nc1cnnc(n1)-c1c[nH]c2c(F)cc(F)cc12 |r,wU:3.2,wD:10.12,(-2.18,3.23,;-1.78,4.72,;-2.87,5.81,;-.3,5.12,;.1,6.6,;1.59,7,;2.68,5.91,;2.28,4.43,;2.02,5.36,;1.26,6.23,;.79,4.03,;.39,2.54,;1.43,1.4,;2.93,1.72,;3.96,.57,;3.49,-.89,;1.98,-1.21,;.95,-.07,;1.5,-2.68,;2.41,-3.92,;1.5,-5.17,;.04,-4.69,;-1.29,-5.46,;-1.29,-7,;-2.63,-4.69,;-2.63,-3.15,;-3.96,-2.38,;-1.29,-2.38,;.04,-3.15,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3KH8
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50190804 (CHEMBL3966074) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1c(Cl)ccc2nc(NC3CC3)ccc12)N1CCC(F)(F)CC1 Show InChI InChI=1S/C25H24ClF5N6O/c26-17-4-5-18-16(3-6-20(36-18)35-15-1-2-15)21(17)22(38)32-13-19(37-9-7-24(27,28)8-10-37)14-11-33-23(34-12-14)25(29,30)31/h3-6,11-12,15,19H,1-2,7-10,13H2,(H,32,38)(H,35,36)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at P2X7 receptor in human whole blood assessed as reduction in LPS/BzATP-induced IL-1beta release preincubated with LPS-stimulate...				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50190911 (CHEMBL3903665) Show SMILES O[C@H]1CCN(C1)c1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 |r| Show InChI InChI=1S/C26H26ClF5N6O2/c27-18-2-3-19-17(1-4-21(36-19)38-8-5-16(39)14-38)22(18)23(40)33-13-20(37-9-6-25(28,29)7-10-37)15-11-34-24(35-12-15)26(30,31)32/h1-4,11-12,16,20,39H,5-10,13-14H2,(H,33,40)/t16-,20?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor assessed as reduction in calcium flux by FLIPR assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Mus musculus)	BDBM50190917 (CHEMBL3918589) Show SMILES CNc1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 Show InChI InChI=1S/C23H22ClF5N6O/c1-30-18-5-2-14-16(34-18)4-3-15(24)19(14)20(36)31-12-17(35-8-6-22(25,26)7-9-35)13-10-32-21(33-11-13)23(27,28)29/h2-5,10-11,17H,6-9,12H2,1H3,(H,30,34)(H,31,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	305	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at mouse P2X7 receptor assessed as reduction in calcium flux by FLIPR calcium flux assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Mus musculus)	BDBM50190797 (CHEMBL3974590) Show SMILES O[C@@H]1CCN(C1)c1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 |r| Show InChI InChI=1S/C26H26ClF5N6O2/c27-18-2-3-19-17(1-4-21(36-19)38-8-5-16(39)14-38)22(18)23(40)33-13-20(37-9-6-25(28,29)7-10-37)15-11-34-24(35-12-15)26(30,31)32/h1-4,11-12,16,20,39H,5-10,13-14H2,(H,33,40)/t16-,20?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at P2X7 receptor in C57/bl6 mouse whole blood assessed as reduction in LPS/BzATP-induced IL-1beta release preincubated with LPS-s...				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50190913 (CHEMBL3912682) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1c(Cl)ccc2nc(ccc12)N1CCOCC1)N1CCC(F)(F)CC1 Show InChI InChI=1S/C26H26ClF5N6O2/c27-18-2-3-19-17(1-4-21(36-19)38-9-11-40-12-10-38)22(18)23(39)33-15-20(37-7-5-25(28,29)6-8-37)16-13-34-24(35-14-16)26(30,31)32/h1-4,13-14,20H,5-12,15H2,(H,33,39)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	376	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at P2X7 receptor in human whole blood assessed as reduction in LPS/BzATP-induced IL-1beta release preincubated with LPS-stimulate...				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Mus musculus)	BDBM50191061 (CHEMBL3893653) Show SMILES CN1CCN(CC1)c1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 Show InChI InChI=1S/C27H29ClF5N7O/c1-38-10-12-40(13-11-38)22-5-2-18-20(37-22)4-3-19(28)23(18)24(41)34-16-21(39-8-6-26(29,30)7-9-39)17-14-35-25(36-15-17)27(31,32)33/h2-5,14-15,21H,6-13,16H2,1H3,(H,34,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	486	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at mouse P2X7 receptor assessed as reduction in calcium flux by FLIPR calcium flux assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Mus musculus)	BDBM50190913 (CHEMBL3912682) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1c(Cl)ccc2nc(ccc12)N1CCOCC1)N1CCC(F)(F)CC1 Show InChI InChI=1S/C26H26ClF5N6O2/c27-18-2-3-19-17(1-4-21(36-19)38-9-11-40-12-10-38)22(18)23(39)33-15-20(37-7-5-25(28,29)6-8-37)16-13-34-24(35-14-16)26(30,31)32/h1-4,13-14,20H,5-12,15H2,(H,33,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at P2X7 receptor in C57/bl6 mouse whole blood assessed as reduction in LPS/BzATP-induced IL-1beta release preincubated with LPS-s...				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Mus musculus)	BDBM50190804 (CHEMBL3966074) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1c(Cl)ccc2nc(NC3CC3)ccc12)N1CCC(F)(F)CC1 Show InChI InChI=1S/C25H24ClF5N6O/c26-17-4-5-18-16(3-6-20(36-18)35-15-1-2-15)21(17)22(38)32-13-19(37-9-7-24(27,28)8-10-37)14-11-33-23(34-12-14)25(29,30)31/h3-6,11-12,15,19H,1-2,7-10,13H2,(H,32,38)(H,35,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at P2X7 receptor in C57/bl6 mouse whole blood assessed as reduction in LPS/BzATP-induced IL-1beta release preincubated with LPS-s...				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Mus musculus)	BDBM50191064 (CHEMBL3894220) Show SMILES Nc1ccc2c(C(=O)NCC(N3CCC(F)(F)CC3)c3cnc(nc3)C(F)(F)F)c(Cl)ccc2n1 Show InChI InChI=1S/C22H20ClF5N6O/c23-14-2-3-15-13(1-4-17(29)33-15)18(14)19(35)30-11-16(34-7-5-21(24,25)6-8-34)12-9-31-20(32-10-12)22(26,27)28/h1-4,9-10,16H,5-8,11H2,(H2,29,33)(H,30,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at mouse P2X7 receptor assessed as reduction in calcium flux by FLIPR calcium flux assay				Bioorg Med Chem Lett 26: 4781-4784 (2016) Article DOI: 10.1016/j.bmcl.2016.08.029 BindingDB Entry DOI: 10.7270/Q2QJ7K7G
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542672 (CHEMBL4643637) Show SMILES Clc1ccc2n(CCCC#N)c(Cn3c4cnccc4n(-c4ncco4)c3=O)cc2c1 Show InChI InChI=1S/C22H17ClN6O2/c23-16-3-4-18-15(11-16)12-17(27(18)9-2-1-6-24)14-28-20-13-25-7-5-19(20)29(22(28)30)21-26-8-10-31-21/h3-5,7-8,10-13H,1-2,9,14H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542673 (CHEMBL4634198) Show SMILES Cn1ccc(n1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O Show InChI InChI=1S/C23H20ClN7O/c1-28-11-7-22(27-28)31-20-6-9-26-14-21(20)30(23(31)32)15-18-13-16-12-17(24)4-5-19(16)29(18)10-3-2-8-25/h4-7,9,11-14H,2-3,10,15H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542674 (CHEMBL4648595) Show SMILES Clc1ccc2n(CCCC#N)c(Cn3c4cnccc4n(-c4ccncc4)c3=O)cc2c1 Show InChI InChI=1S/C24H19ClN6O/c25-18-3-4-21-17(13-18)14-20(29(21)12-2-1-8-26)16-30-23-15-28-11-7-22(23)31(24(30)32)19-5-9-27-10-6-19/h3-7,9-11,13-15H,1-2,12,16H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542675 (CHEMBL4644767) Show SMILES Fc1cnccc1-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O |(29.27,-3.65,;27.77,-3.33,;27.29,-1.86,;25.79,-1.54,;24.75,-2.69,;25.23,-4.15,;26.73,-4.47,;27.21,-5.93,;28.67,-6.41,;30,-5.63,;31.34,-6.4,;31.34,-7.95,;30.01,-8.72,;28.67,-7.95,;27.21,-8.43,;26.73,-9.89,;25.22,-10.21,;24.08,-9.17,;22.75,-9.94,;21.29,-9.47,;20.14,-10.49,;18.68,-10.02,;20.47,-12,;21.92,-12.47,;23.06,-11.45,;24.59,-11.61,;25.36,-12.95,;26.9,-12.95,;27.67,-14.28,;29.21,-14.29,;30.75,-14.28,;26.3,-7.18,;24.76,-7.18,)| Show InChI InChI=1S/C24H18ClFN6O/c25-17-3-4-20-16(11-17)12-18(30(20)10-2-1-7-27)15-31-23-14-29-9-6-22(23)32(24(31)33)21-5-8-28-13-19(21)26/h3-6,8-9,11-14H,1-2,10,15H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.316	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50088178 (BMS-433771 | CHEMBL243876) Show SMILES OCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)nc2ccccc12 Show InChI InChI=1S/C21H23N5O2/c27-12-4-3-11-24-17-6-2-1-5-16(17)23-20(24)14-25-19-13-22-10-9-18(19)26(21(25)28)15-7-8-15/h1-2,5-6,9-10,13,15,27H,3-4,7-8,11-12,14H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542609 (CHEMBL4646086) Show SMILES OCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)nc2ncccc12 Show InChI InChI=1S/C20H22N6O2/c27-11-2-1-10-24-16-4-3-8-22-19(16)23-18(24)13-25-17-12-21-9-7-15(17)26(20(25)28)14-5-6-14/h3-4,7-9,12,14,27H,1-2,5-6,10-11,13H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542610 (CHEMBL4643207) Show SMILES CC(C)CCn1c(Cn2c3cnccc3n(C3CC3)c2=O)nc2ncccc12 Show InChI InChI=1S/C21H24N6O/c1-14(2)8-11-25-17-4-3-9-23-20(17)24-19(25)13-26-18-12-22-10-7-16(18)27(21(26)28)15-5-6-15/h3-4,7,9-10,12,14-15H,5-6,8,11,13H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542611 (CHEMBL4644823) Show SMILES OCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)nc2cnccc12 Show InChI InChI=1S/C20H22N6O2/c27-10-2-1-9-24-16-5-7-21-11-15(16)23-19(24)13-25-18-12-22-8-6-17(18)26(20(25)28)14-3-4-14/h5-8,11-12,14,27H,1-4,9-10,13H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542612 (CHEMBL4637235) Show SMILES CC(C)CCn1c(Cn2c3cnccc3n(C3CC3)c2=O)nc2cnccc12 Show InChI InChI=1S/C21H24N6O/c1-14(2)7-10-25-17-5-8-22-11-16(17)24-20(25)13-26-19-12-23-9-6-18(19)27(21(26)28)15-3-4-15/h5-6,8-9,11-12,14-15H,3-4,7,10,13H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542613 (CHEMBL4632708) Show SMILES CC(C)CCn1c(Cn2c3cnccc3n(C3CC3)c2=O)nc2ccncc12 Show InChI InChI=1S/C21H24N6O/c1-14(2)7-10-25-18-11-22-8-5-16(18)24-20(25)13-26-19-12-23-9-6-17(19)27(21(26)28)15-3-4-15/h5-6,8-9,11-12,14-15H,3-4,7,10,13H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542614 (CHEMBL4632434) Show SMILES CC(C)CCn1c(Cn2c3cnccc3n(C3CC3)c2=O)nc2cccnc12 Show InChI InChI=1S/C21H24N6O/c1-14(2)8-11-25-19(24-16-4-3-9-23-20(16)25)13-26-18-12-22-10-7-17(18)27(21(26)28)15-5-6-15/h3-4,7,9-10,12,14-15H,5-6,8,11,13H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542615 (CHEMBL4640277) Show SMILES OCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2ncccc12 Show InChI InChI=1S/C21H23N5O2/c27-11-2-1-10-24-16(12-17-18(24)4-3-8-23-17)14-25-20-13-22-9-7-19(20)26(21(25)28)15-5-6-15/h3-4,7-9,12-13,15,27H,1-2,5-6,10-11,14H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	158	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542616 (CHEMBL4640814) Show SMILES OCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cnccc12 Show InChI InChI=1S/C21H23N5O2/c27-10-2-1-9-24-17(11-15-12-22-7-5-18(15)24)14-25-20-13-23-8-6-19(20)26(21(25)28)16-3-4-16/h5-8,11-13,16,27H,1-4,9-10,14H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542617 (CHEMBL4636898) Show SMILES OCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2ccncc12 Show InChI InChI=1S/C21H23N5O2/c27-10-2-1-9-24-17(11-15-5-7-22-12-19(15)24)14-25-20-13-23-8-6-18(20)26(21(25)28)16-3-4-16/h5-8,11-13,16,27H,1-4,9-10,14H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	126	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542618 (CHEMBL4636449) Show SMILES CC(C)CCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cccnc12 Show InChI InChI=1S/C22H25N5O/c1-15(2)8-11-25-18(12-16-4-3-9-24-21(16)25)14-26-20-13-23-10-7-19(20)27(22(26)28)17-5-6-17/h3-4,7,9-10,12-13,15,17H,5-6,8,11,14H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542619 (CHEMBL4643019) Show SMILES CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2ccccc12 Show InChI InChI=1S/C22H24N4O3S/c1-30(28,29)12-4-11-24-18(13-16-5-2-3-6-19(16)24)15-25-21-14-23-10-9-20(21)26(22(25)27)17-7-8-17/h2-3,5-6,9-10,13-14,17H,4,7-8,11-12,15H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542620 (CHEMBL4644851) Show SMILES CC(C)CCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2ccccc12 Show InChI InChI=1S/C23H26N4O/c1-16(2)10-12-25-19(13-17-5-3-4-6-20(17)25)15-26-22-14-24-11-9-21(22)27(23(26)28)18-7-8-18/h3-6,9,11,13-14,16,18H,7-8,10,12,15H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542621 (CHEMBL4642446) Show SMILES OCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cc(F)ccc12 Show InChI InChI=1S/C22H23FN4O2/c23-16-3-6-19-15(11-16)12-18(25(19)9-1-2-10-28)14-26-21-13-24-8-7-20(21)27(22(26)29)17-4-5-17/h3,6-8,11-13,17,28H,1-2,4-5,9-10,14H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542622 (CHEMBL4638215) Show SMILES CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cc(F)ccc12 Show InChI InChI=1S/C22H23FN4O3S/c1-31(29,30)10-2-9-25-18(12-15-11-16(23)3-6-19(15)25)14-26-21-13-24-8-7-20(21)27(22(26)28)17-4-5-17/h3,6-8,11-13,17H,2,4-5,9-10,14H2,1H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair
Fusion glycoprotein F0 (Human respiratory syncytial virus)	BDBM50542623 (CHEMBL4459588) Show SMILES OCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cc(Cl)ccc12 Show InChI InChI=1S/C22H23ClN4O2/c23-16-3-6-19-15(11-16)12-18(25(19)9-1-2-10-28)14-26-21-13-24-8-7-20(21)27(22(26)29)17-4-5-17/h3,6-8,11-13,17,28H,1-2,4-5,9-10,14H2	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...				J Med Chem 63: 8046-8058 (2020) Article DOI: 10.1021/acs.jmedchem.0c00226 BindingDB Entry DOI: 10.7270/Q27H1P5V
					More data for this Ligand-Target Pair

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