Compile Data Set for Download or QSAR

Found 21 hits with Last Name = 'de lellis' and Initial = 'l'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540553 (CHEMBL4644726) Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)C(C)(C)Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1 Show InChI InChI=1S/C31H31N3O5S/c1-23-9-19-29(20-10-23)40(36,37)34-30(35)31(2,3)39-28-15-11-24(12-16-28)21-22-38-27-17-13-26(14-18-27)33-32-25-7-5-4-6-8-25/h4-20H,21-22H2,1-3H3,(H,34,35)/b33-32+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540555 (CHEMBL4642691) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C30H28ClN3O5S/c1-30(2,29(35)34-40(36,37)28-18-10-23(31)11-19-28)39-27-14-8-22(9-15-27)20-21-38-26-16-12-25(13-17-26)33-32-24-6-4-3-5-7-24/h3-19H,20-21H2,1-2H3,(H,34,35)/b33-32+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540566 (CHEMBL4636567) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(NC(=O)c3ccccc3)cc2)cc1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C31H30N2O6S/c1-31(2,30(35)33-40(36,37)28-11-7-4-8-12-28)39-27-17-13-23(14-18-27)21-22-38-26-19-15-25(16-20-26)32-29(34)24-9-5-3-6-10-24/h3-20H,21-22H2,1-2H3,(H,32,34)(H,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540554 (CHEMBL4636810) Show SMILES COc1ccc(cc1)S(=O)(=O)NC(=O)C(C)(C)Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1 Show InChI InChI=1S/C31H31N3O6S/c1-31(2,30(35)34-41(36,37)29-19-17-26(38-3)18-20-29)40-28-13-9-23(10-14-28)21-22-39-27-15-11-25(12-16-27)33-32-24-7-5-4-6-8-24/h4-20H,21-22H2,1-3H3,(H,34,35)/b33-32+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540556 (CHEMBL4636520) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1)C(=O)NS(=O)(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C30H28N4O7S/c1-30(2,29(35)33-42(38,39)28-18-12-25(13-19-28)34(36)37)41-27-14-8-22(9-15-27)20-21-40-26-16-10-24(11-17-26)32-31-23-6-4-3-5-7-23/h3-19H,20-21H2,1-2H3,(H,33,35)/b32-31+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540552 (CHEMBL4636990) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C30H29N3O5S/c1-30(2,29(34)33-39(35,36)28-11-7-4-8-12-28)38-27-17-13-23(14-18-27)21-22-37-26-19-15-25(16-20-26)32-31-24-9-5-3-6-10-24/h3-20H,21-22H2,1-2H3,(H,33,34)/b32-31+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540557 (CHEMBL4642679) Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NC(=O)C(C)(C)Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1 Show InChI InChI=1S/C32H32N4O6S/c1-23(37)33-25-13-19-30(20-14-25)43(39,40)36-31(38)32(2,3)42-29-15-9-24(10-16-29)21-22-41-28-17-11-27(12-18-28)35-34-26-7-5-4-6-8-26/h4-20H,21-22H2,1-3H3,(H,33,37)(H,36,38)/b35-34+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540571 (CHEMBL4632967) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(NC(=O)Nc3ccccc3)cc2)cc1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C31H31N3O6S/c1-31(2,29(35)34-41(37,38)28-11-7-4-8-12-28)40-27-17-13-23(14-18-27)21-22-39-26-19-15-25(16-20-26)33-30(36)32-24-9-5-3-6-10-24/h3-20H,21-22H2,1-2H3,(H,34,35)(H2,32,33,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540568 (CHEMBL4634884) Show SMILES CCCCNC(=O)C(C)(C)Oc1ccc(CCOc2ccc(NC(=O)Nc3ccccc3)cc2)cc1 Show InChI InChI=1S/C29H35N3O4/c1-4-5-20-30-27(33)29(2,3)36-26-15-11-22(12-16-26)19-21-35-25-17-13-24(14-18-25)32-28(34)31-23-9-7-6-8-10-23/h6-18H,4-5,19-21H2,1-3H3,(H,30,33)(H2,31,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540561 (CHEMBL4643748) Show SMILES CCCCNC(=O)C(C)(C)Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1 Show InChI InChI=1S/C28H33N3O3/c1-4-5-20-29-27(32)28(2,3)34-26-15-11-22(12-16-26)19-21-33-25-17-13-24(14-18-25)31-30-23-9-7-6-8-10-23/h6-18H,4-5,19-21H2,1-3H3,(H,29,32)/b31-30+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540562 (CHEMBL4649566) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C31H31N3O3/c1-31(2,30(35)32-23-25-9-5-3-6-10-25)37-29-17-13-24(14-18-29)21-22-36-28-19-15-27(16-20-28)34-33-26-11-7-4-8-12-26/h3-20H,21-23H2,1-2H3,(H,32,35)/b34-33+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540558 (CHEMBL4641671) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1)C(=O)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C37H34N4O6S/c1-37(2,36(43)41-48(44,45)34-23-17-29(18-24-34)38-35(42)28-9-5-3-6-10-28)47-33-19-13-27(14-20-33)25-26-46-32-21-15-31(16-22-32)40-39-30-11-7-4-8-12-30/h3-24H,25-26H2,1-2H3,(H,38,42)(H,41,43)/b40-39+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540560 (CHEMBL4635054) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1)C(N)=O Show InChI InChI=1S/C24H25N3O3/c1-24(2,23(25)28)30-22-12-8-18(9-13-22)16-17-29-21-14-10-20(11-15-21)27-26-19-6-4-3-5-7-19/h3-15H,16-17H2,1-2H3,(H2,25,28)/b27-26+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540559 (CHEMBL4638499) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1)C(=O)NS(=O)(=O)c1ccc(NC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C38H36N4O6S/c1-38(2,37(44)42-49(45,46)35-23-17-30(18-24-35)39-36(43)27-29-9-5-3-6-10-29)48-34-19-13-28(14-20-34)25-26-47-33-21-15-32(16-22-33)41-40-31-11-7-4-8-12-31/h3-24H,25-27H2,1-2H3,(H,39,43)(H,42,44)/b41-40+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540567 (CHEMBL4647531) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(NC(=O)Nc3ccccc3)cc2)cc1)C(N)=O Show InChI InChI=1S/C25H27N3O4/c1-25(2,23(26)29)32-22-12-8-18(9-13-22)16-17-31-21-14-10-20(11-15-21)28-24(30)27-19-6-4-3-5-7-19/h3-15H,16-17H2,1-2H3,(H2,26,29)(H2,27,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540569 (CHEMBL4635727) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(NC(=O)Nc3ccccc3)cc2)cc1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C31H31N3O4/c1-31(2,29(35)32-24-9-5-3-6-10-24)38-28-17-13-23(14-18-28)21-22-37-27-19-15-26(16-20-27)34-30(36)33-25-11-7-4-8-12-25/h3-20H,21-22H2,1-2H3,(H,32,35)(H2,33,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540563 (CHEMBL4644539) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(NC(=O)c3ccccc3)cc2)cc1)C(N)=O Show InChI InChI=1S/C25H26N2O4/c1-25(2,24(26)29)31-22-12-8-18(9-13-22)16-17-30-21-14-10-20(11-15-21)27-23(28)19-6-4-3-5-7-19/h3-15H,16-17H2,1-2H3,(H2,26,29)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540570 (CHEMBL4639127) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(NC(=O)Nc3ccccc3)cc2)cc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C32H33N3O4/c1-32(2,30(36)33-23-25-9-5-3-6-10-25)39-29-17-13-24(14-18-29)21-22-38-28-19-15-27(16-20-28)35-31(37)34-26-11-7-4-8-12-26/h3-20H,21-23H2,1-2H3,(H,33,36)(H2,34,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540565 (CHEMBL4641643) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(NC(=O)c3ccccc3)cc2)cc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C32H32N2O4/c1-32(2,31(36)33-23-25-9-5-3-6-10-25)38-29-17-13-24(14-18-29)21-22-37-28-19-15-27(16-20-28)34-30(35)26-11-7-4-8-12-26/h3-20H,21-23H2,1-2H3,(H,33,36)(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50540564 (CHEMBL4648827) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(NC(=O)c3ccccc3)cc2)cc1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C31H30N2O4/c1-31(2,30(35)33-25-11-7-4-8-12-25)37-28-17-13-23(14-18-28)21-22-36-27-19-15-26(16-20-27)32-29(34)24-9-5-3-6-10-24/h3-20H,21-22H2,1-2H3,(H,32,34)(H,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50540552 (CHEMBL4636990) Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C30H29N3O5S/c1-30(2,29(34)33-39(35,36)28-11-7-4-8-12-28)38-27-17-13-23(14-18-27)21-22-37-26-19-15-25(16-20-26)32-31-24-9-5-3-6-10-24/h3-20H,21-22H2,1-2H3,(H,33,34)/b32-31+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARgamma LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020) Article DOI: 10.1021/acsmedchemlett.9b00666 BindingDB Entry DOI: 10.7270/Q2765JW1
					More data for this Ligand-Target Pair