Compile Data Set for Download or QSAR

Found 1372 hits with Last Name = 'konkol' and Initial = 'lc'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 [808-1132] (Homo sapiens (Human))	BDBM620451 (US11767323, Example 1) Show SMILES CS(=O)(=O)C1CCN(Cc2ccc(cc2)-c2cc3c(ncc4[nH]c(=O)c(cc34)-c3ccccc3)[nH]2)CC1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [826-1132] (Homo sapiens (Human))	BDBM620452 (US11767323, Example 2) Show SMILES CS(=O)(=O)C1CCN(Cc2ccc(cc2)-c2cc3c(ncc4[nH]c(=O)c(cc34)-c3ccc(cc3)C(O)=O)[nH]2)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [808-1132] (Homo sapiens (Human))	BDBM620452 (US11767323, Example 2) Show SMILES CS(=O)(=O)C1CCN(Cc2ccc(cc2)-c2cc3c(ncc4[nH]c(=O)c(cc34)-c3ccc(cc3)C(O)=O)[nH]2)CC1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [808-1132] (Homo sapiens (Human))	BDBM620456 (US11767323, Example 6) Show SMILES Cc1c(-c2ccc(cc2)C(O)=O)c(=O)[nH]c2cnc3[nH]c(cc3c12)-c1ccc(CN2CCC(CC2)S(C)(=O)=O)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [808-1132] (Homo sapiens (Human))	BDBM620453 (US11767323, Example 3) Show SMILES CS(=O)(=O)C1CCN(Cc2ccc(cc2)-c2cc3c(ncc4[nH]c(=O)c(cc34)C#N)[nH]2)CC1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [826-1132] (Homo sapiens (Human))	BDBM620455 (US11767323, Example 5) Show SMILES CS(=O)(=O)C1CCN(Cc2ccc(cc2)-c2cc3c(ncc4[nH]c(=O)c(cc34)-c3nnn[nH]3)[nH]2)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [826-1132] (Homo sapiens (Human))	BDBM620456 (US11767323, Example 6) Show SMILES Cc1c(-c2ccc(cc2)C(O)=O)c(=O)[nH]c2cnc3[nH]c(cc3c12)-c1ccc(CN2CCC(CC2)S(C)(=O)=O)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [826-1132] (Homo sapiens (Human))	BDBM620453 (US11767323, Example 3) Show SMILES CS(=O)(=O)C1CCN(Cc2ccc(cc2)-c2cc3c(ncc4[nH]c(=O)c(cc34)C#N)[nH]2)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105653 (US10047086, 116 | US10640503, Example 116 | US9695...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnc4N(C)CCOc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C29H30N6O2/c1-33-9-3-4-21(17-33)18-37-26-13-24(22-7-5-20(14-30)6-8-22)28(35-19-31-16-25(26)35)23-12-27-29(32-15-23)34(2)10-11-36-27/h5-8,12-13,15-16,19,21H,3-4,9-11,17-18H2,1-2H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105672 (US10047086, 120 | US10640503, Example 120 | US9695...) Show SMILES CC(O)CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3ccc4nccnc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C31H30N6O2/c1-21(38)17-36-12-2-3-23(18-36)19-39-30-14-26(24-6-4-22(15-32)5-7-24)31(37-20-33-16-29(30)37)25-8-9-27-28(13-25)35-11-10-34-27/h4-11,13-14,16,20-21,23,38H,2-3,12,17-19H2,1H3/t21?,23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105686 (US10047086, 121 | US10640503, Example 121 | US9695...) Show SMILES COCCN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnc4ccoc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C30H29N5O3/c1-36-12-10-34-9-2-3-22(18-34)19-38-29-14-25(23-6-4-21(15-31)5-7-23)30(35-20-32-17-27(29)35)24-13-28-26(33-16-24)8-11-37-28/h4-8,11,13-14,16-17,20,22H,2-3,9-10,12,18-19H2,1H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105693 (US10047086, 122 | US10640503, Example 122 | US9695...) Show SMILES COCCN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnc4OCCCc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C31H33N5O3/c1-37-13-11-35-10-2-4-23(19-35)20-39-29-15-27(24-8-6-22(16-32)7-9-24)30(36-21-33-18-28(29)36)26-14-25-5-3-12-38-31(25)34-17-26/h6-9,14-15,17-18,21,23H,2-5,10-13,19-20H2,1H3/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105695 (US10047086, 123 | US10640503, Example 123 | US9695...) Show SMILES CC(O)c1ccc(cc1)-c1c(cc(OC[C@@H]2CCCN(C)C2)c2cncn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C29H30N4O2/c1-20(34)23-9-11-25(12-10-23)29-26(24-7-5-21(15-30)6-8-24)14-28(27-16-31-19-33(27)29)35-18-22-4-3-13-32(2)17-22/h5-12,14,16,19-20,22,34H,3-4,13,17-18H2,1-2H3/t20?,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105733 (US10047086, 125 | US10640503, Example 125 | US9695...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3ccc(C)nc3)n3cncc23)C1 |r| Show InChI InChI=1S/C27H27N5O/c1-19-5-8-23(14-30-19)27-24(22-9-6-20(13-28)7-10-22)12-26(25-15-29-18-32(25)27)33-17-21-4-3-11-31(2)16-21/h5-10,12,14-15,18,21H,3-4,11,16-17H2,1-2H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105736 (US10047086, 126 | US10640503, Example 126 | US9695...) Show SMILES CC(O)c1c(C)cc(cc1F)-c1c(cc(OC[C@@H]2CCCN(C)C2)c2cncn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C30H31FN4O2/c1-19-11-24(12-26(31)29(19)20(2)36)30-25(23-8-6-21(14-32)7-9-23)13-28(27-15-33-18-35(27)30)37-17-22-5-4-10-34(3)16-22/h6-9,11-13,15,18,20,22,36H,4-5,10,16-17H2,1-3H3/t20?,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105760 (US10047086, 127 | US10640503, Example 127 | US9695...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnc(C)c(F)c3)n3cncc23)C1 |r| Show InChI InChI=1S/C27H26FN5O/c1-18-24(28)10-22(13-31-18)27-23(21-7-5-19(12-29)6-8-21)11-26(25-14-30-17-33(25)27)34-16-20-4-3-9-32(2)15-20/h5-8,10-11,13-14,17,20H,3-4,9,15-16H2,1-2H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105762 (US10047086, 128 | US10640503, Example 128 | US9695...) Show SMILES CCN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cc(C)c(CO)c(F)c3)n3cncc23)C1 |r| Show InChI InChI=1S/C30H31FN4O2/c1-3-34-10-4-5-22(16-34)18-37-29-13-25(23-8-6-21(14-32)7-9-23)30(35-19-33-15-28(29)35)24-11-20(2)26(17-36)27(31)12-24/h6-9,11-13,15,19,22,36H,3-5,10,16-18H2,1-2H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105764 (US10047086, 129 | US10640503, Example 129 | US9695...) Show SMILES COCCN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cc(C)c(CO)c(F)c3)n3cncc23)C1 |r| Show InChI InChI=1S/C31H33FN4O3/c1-21-12-25(13-28(32)27(21)18-37)31-26(24-7-5-22(15-33)6-8-24)14-30(29-16-34-20-36(29)31)39-19-23-4-3-9-35(17-23)10-11-38-2/h5-8,12-14,16,20,23,37H,3-4,9-11,17-19H2,1-2H3/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105777 (US10047086, 130 | US10640503, Example 130 | US9695...) Show SMILES COCCN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnc(C)c(C)c3)n3cncc23)C1 |r| Show InChI InChI=1S/C30H33N5O2/c1-21-13-26(16-33-22(21)2)30-27(25-8-6-23(15-31)7-9-25)14-29(28-17-32-20-35(28)30)37-19-24-5-4-10-34(18-24)11-12-36-3/h6-9,13-14,16-17,20,24H,4-5,10-12,18-19H2,1-3H3/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105779 (US10047086, 131 | US10640503, Example 131 | US9695...) Show SMILES CCN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnc(C)c(C)c3)n3cncc23)C1 |r| Show InChI InChI=1S/C29H31N5O/c1-4-33-11-5-6-23(17-33)18-35-28-13-26(24-9-7-22(14-30)8-10-24)29(34-19-31-16-27(28)34)25-12-20(2)21(3)32-15-25/h7-10,12-13,15-16,19,23H,4-6,11,17-18H2,1-3H3/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105842 (US10047086, 134 | US10640503, Example 134 | US9695...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnn(c3)C3CCC3)n3cncc23)C1 |r| Show InChI InChI=1S/C28H30N6O/c1-32-11-3-4-21(16-32)18-35-27-12-25(22-9-7-20(13-29)8-10-22)28(33-19-30-15-26(27)33)23-14-31-34(17-23)24-5-2-6-24/h7-10,12,14-15,17,19,21,24H,2-6,11,16,18H2,1H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105877 (US10047086, 136 | US10640503, Example 136 | US9695...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3CC(O)Cc3c2)n2cncc12 Show InChI InChI=1S/C29H30N6O/c1-33(2)24-9-11-34(12-10-24)29-26-17-31-18-35(26)28(22-8-7-21-14-25(36)15-23(21)13-22)27(32-29)20-5-3-19(16-30)4-6-20/h3-8,13,17-18,24-25,36H,9-12,14-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105878 (US10047086, 137 | US10640503, Example 137 | US9695...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3N(C)C(=O)CCc3c2)n2cncc12 Show InChI InChI=1S/C30H31N7O/c1-34(2)24-12-14-36(15-13-24)30-26-18-32-19-37(26)29(28(33-30)21-6-4-20(17-31)5-7-21)23-8-10-25-22(16-23)9-11-27(38)35(25)3/h4-8,10,16,18-19,24H,9,11-15H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105879 (US10047086, 138 | US10640503, Example 138 | US9695...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cc(F)c3n(C)c(=O)n(C)c3c2)n2cncc12 Show InChI InChI=1S/C29H29FN8O/c1-34(2)21-9-11-37(12-10-21)28-24-16-32-17-38(24)26(25(33-28)19-7-5-18(15-31)6-8-19)20-13-22(30)27-23(14-20)35(3)29(39)36(27)4/h5-8,13-14,16-17,21H,9-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105880 (US10047086, 139 | US10640503, Example 139 | US9695...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnn(c2)C2CCC2)n2cncc12 Show InChI InChI=1S/C27H30N8/c1-32(2)22-10-12-33(13-11-22)27-24-16-29-18-34(24)26(21-15-30-35(17-21)23-4-3-5-23)25(31-27)20-8-6-19(14-28)7-9-20/h6-9,15-18,22-23H,3-5,10-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105901 (US10047086, 142 | US10640503, Example 142 | US9695...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc(C)c(CO)c2)n2cncc12 Show InChI InChI=1S/C27H29N7O/c1-18-22(16-35)12-21(14-30-18)26-25(20-6-4-19(13-28)5-7-20)31-27(24-15-29-17-34(24)26)33-10-8-23(9-11-33)32(2)3/h4-7,12,14-15,17,23,35H,8-11,16H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105905 (US10047086, 143 | US10640503, Example 143 | US9695...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3n(C)c(nc3c2)C(F)F)n2cncc12 Show InChI InChI=1S/C29H28F2N8/c1-36(2)21-10-12-38(13-11-21)28-24-16-33-17-39(24)26(25(35-28)19-6-4-18(15-32)5-7-19)20-8-9-23-22(14-20)34-29(27(30)31)37(23)3/h4-9,14,16-17,21,27H,10-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105913 (US10047086, 144 | US10640503, Example 144 | US9695...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc3ccccc3c2)n2cncc12 Show InChI InChI=1S/C29H27N7/c1-34(2)24-11-13-35(14-12-24)29-26-18-31-19-36(26)28(23-15-22-5-3-4-6-25(22)32-17-23)27(33-29)21-9-7-20(16-30)8-10-21/h3-10,15,17-19,24H,11-14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105916 (US10047086, 145 | US10640503, Example 145 | US9695...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3ncccc3c2)n2cncc12 Show InChI InChI=1S/C29H27N7/c1-34(2)24-11-14-35(15-12-24)29-26-18-31-19-36(26)28(23-9-10-25-22(16-23)4-3-13-32-25)27(33-29)21-7-5-20(17-30)6-8-21/h3-10,13,16,18-19,24H,11-12,14-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM106012 (US10047086, 148 | US10640503, Example 148 | US9695...) Show SMILES COc1ncc(cc1C#N)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C27H26N8O/c1-33(2)22-8-10-34(11-9-22)26-23-16-30-17-35(23)25(21-12-20(14-29)27(36-3)31-15-21)24(32-26)19-6-4-18(13-28)5-7-19/h4-7,12,15-17,22H,8-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM106019 (US10047086, 149 | US10640503, Example 149 | US9695...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(CO)c(C)c2)n2cncc12 Show InChI InChI=1S/C28H30N6O/c1-19-14-22(8-9-23(19)17-35)27-26(21-6-4-20(15-29)5-7-21)31-28(25-16-30-18-34(25)27)33-12-10-24(11-13-33)32(2)3/h4-9,14,16,18,24,35H,10-13,17H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM106070 (US10047086, 153 | US10640503, Example 153 | US9695...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3ccc4n(C)c(C)nc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C30H30N6O/c1-20-33-26-13-24(10-11-27(26)35(20)3)30-25(23-8-6-21(15-31)7-9-23)14-29(28-16-32-19-36(28)30)37-18-22-5-4-12-34(2)17-22/h6-11,13-14,16,19,22H,4-5,12,17-18H2,1-3H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105901 (US10047086, 142 | US10640503, Example 142 | US9695...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2cnc(C)c(CO)c2)n2cncc12 Show InChI InChI=1S/C27H29N7O/c1-18-22(16-35)12-21(14-30-18)26-25(20-6-4-19(13-28)5-7-20)31-27(24-15-29-17-34(24)26)33-10-8-23(9-11-33)32(2)3/h4-7,12,14-15,17,23,35H,8-11,16H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10047086 (2018) BindingDB Entry DOI: 10.7270/Q28917W4
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105760 (US10047086, 127 | US10640503, Example 127 | US9695...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnc(C)c(F)c3)n3cncc23)C1 |r| Show InChI InChI=1S/C27H26FN5O/c1-18-24(28)10-22(13-31-18)27-23(21-7-5-19(12-29)6-8-21)11-26(25-14-30-17-33(25)27)34-16-20-4-3-9-32(2)15-20/h5-8,10-11,13-14,17,20H,3-4,9,15-16H2,1-2H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10047086 (2018) BindingDB Entry DOI: 10.7270/Q28917W4
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A [151-852] (Homo sapiens (Human))	BDBM103891 (US10047086, 5 | US10640503, Example 5 | US9695168,...) Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCNC2)c2cncn12)-c1ccc(cc1F)C#N |r| Show InChI InChI=1S/C26H23FN4O/c1-17-2-5-20(6-3-17)26-22(21-7-4-18(12-28)10-23(21)27)11-25(24-14-30-16-31(24)26)32-15-19-8-9-29-13-19/h2-7,10-11,14,16,19,29H,8-9,13,15H2,1H3/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...				US Patent US9695168 (2017) BindingDB Entry DOI: 10.7270/Q2SX6BCD
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A [151-852] (Homo sapiens (Human))	BDBM103900 (US10047086, 14 | US10640503, Example 14 | US969516...) Show SMILES CN1CCOc2cc(ccc12)-c1c(cc(OC[C@@H]2CCNC2)c2cncn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C28H27N5O2/c1-32-10-11-34-26-12-22(6-7-24(26)32)28-23(21-4-2-19(14-29)3-5-21)13-27(25-16-31-18-33(25)28)35-17-20-8-9-30-15-20/h2-7,12-13,16,18,20,30H,8-11,15,17H2,1H3/t20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...				US Patent US9695168 (2017) BindingDB Entry DOI: 10.7270/Q2SX6BCD
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A [151-852] (Homo sapiens (Human))	BDBM105530 (US10047086, 80 | US10640503, Example 80 | US969516...) Show SMILES CN(C)c1ccc(cn1)-c1c(cc(OC[C@@H]2CCCN(C)C2)c2cncn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C28H30N6O/c1-32(2)27-11-10-23(15-31-27)28-24(22-8-6-20(14-29)7-9-22)13-26(25-16-30-19-34(25)28)35-18-21-5-4-12-33(3)17-21/h6-11,13,15-16,19,21H,4-5,12,17-18H2,1-3H3/t21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...				US Patent US9695168 (2017) BindingDB Entry DOI: 10.7270/Q2SX6BCD
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM104681 (US10047086, 51 | US10640503, Example 51 | US969516...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc3n(C)c(=O)oc3c2)n2cncc12 Show InChI InChI=1S/C28H27N7O2/c1-32(2)21-10-12-34(13-11-21)27-23-16-30-17-35(23)26(25(31-27)19-6-4-18(15-29)5-7-19)20-8-9-22-24(14-20)37-28(36)33(22)3/h4-9,14,16-17,21H,10-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM104918 (US10047086, 53 | US10640503, Example 53 | US969516...) Show SMILES COc1ccc(cn1)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C26H27N7O/c1-31(2)21-10-12-32(13-11-21)26-22-16-28-17-33(22)25(20-8-9-23(34-3)29-15-20)24(30-26)19-6-4-18(14-27)5-7-19/h4-9,15-17,21H,10-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM104923 (US10047086, 54 | US10640503, Example 54 | US969516...) Show SMILES CN(C)C1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(nc2)N2CCCC2=O)n2cncc12 Show InChI InChI=1S/C29H30N8O/c1-34(2)23-11-14-35(15-12-23)29-24-18-31-19-37(24)28(27(33-29)21-7-5-20(16-30)6-8-21)22-9-10-25(32-17-22)36-13-3-4-26(36)38/h5-10,17-19,23H,3-4,11-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM104926 (US10047086, 56 | US10640503, Example 56 | US969516...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3ccc4nccnc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C29H26N6O/c1-34-12-2-3-21(17-34)18-36-28-14-24(22-6-4-20(15-30)5-7-22)29(35-19-31-16-27(28)35)23-8-9-25-26(13-23)33-11-10-32-25/h4-11,13-14,16,19,21H,2-3,12,17-18H2,1H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM104928 (US10047086, 57 | US10640503, Example 57 | US969516...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnc4n(C)c(=O)oc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C28H26N6O3/c1-32-9-3-4-19(15-32)16-36-24-11-22(20-7-5-18(12-29)6-8-20)26(34-17-30-14-23(24)34)21-10-25-27(31-13-21)33(2)28(35)37-25/h5-8,10-11,13-14,17,19H,3-4,9,15-16H2,1-2H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM104983 (US10047086, 58 | US10640503, Example 58 | US969516...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnc4n(C)cnc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C28H27N7O/c1-33-9-3-4-20(15-33)16-36-26-11-23(21-7-5-19(12-29)6-8-21)27(35-17-30-14-25(26)35)22-10-24-28(31-13-22)34(2)18-32-24/h5-8,10-11,13-14,17-18,20H,3-4,9,15-16H2,1-2H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105055 (US10047086, 62 | US10640503, Example 62 | US969516...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnc4OCCOc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C28H27N5O3/c1-32-8-2-3-20(16-32)17-36-25-12-23(21-6-4-19(13-29)5-7-21)27(33-18-30-15-24(25)33)22-11-26-28(31-14-22)35-10-9-34-26/h4-7,11-12,14-15,18,20H,2-3,8-10,16-17H2,1H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105087 (US10047086, 63 | US10640503, Example 63 | US969516...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3ccc4n(C)c(=O)oc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C29H27N5O3/c1-32-11-3-4-20(16-32)17-36-26-13-23(21-7-5-19(14-30)6-8-21)28(34-18-31-15-25(26)34)22-9-10-24-27(12-22)37-29(35)33(24)2/h5-10,12-13,15,18,20H,3-4,11,16-17H2,1-2H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105122 (US10047086, 64 | US10640503, Example 64 | US969516...) Show SMILES CN1C(=O)Cc2cc(ccc12)-c1c(cc(OC[C@@H]2CCCN(C)C2)c2cncn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C30H29N5O2/c1-33-11-3-4-21(17-33)18-37-28-14-25(22-7-5-20(15-31)6-8-22)30(35-19-32-16-27(28)35)23-9-10-26-24(12-23)13-29(36)34(26)2/h5-10,12,14,16,19,21H,3-4,11,13,17-18H2,1-2H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105127 (US10047086, 65 | US10640503, Example 65 | US969516...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3ccc4N(C)C(=O)COc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C30H29N5O3/c1-33-11-3-4-21(16-33)17-37-28-13-24(22-7-5-20(14-31)6-8-22)30(35-19-32-15-26(28)35)23-9-10-25-27(12-23)38-18-29(36)34(25)2/h5-10,12-13,15,19,21H,3-4,11,16-18H2,1-2H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105136 (US10047086, 67 | US10640503, Example 67 | US969516...) Show SMILES CCN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnc4OCCOc4c3)n3cncc23)C1 |r| Show InChI InChI=1S/C29H29N5O3/c1-2-33-9-3-4-21(17-33)18-37-26-13-24(22-7-5-20(14-30)6-8-22)28(34-19-31-16-25(26)34)23-12-27-29(32-15-23)36-11-10-35-27/h5-8,12-13,15-16,19,21H,2-4,9-11,17-18H2,1H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105170 (US10047086, 70 | US10640503, Example 70 | US969516...) Show SMILES COc1ncc(cc1F)-c1c(cc(OC[C@@H]2CCCN(C)C2)c2cncn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C27H26FN5O2/c1-32-9-3-4-19(15-32)16-35-25-11-22(20-7-5-18(12-29)6-8-20)26(33-17-30-14-24(25)33)21-10-23(28)27(34-2)31-13-21/h5-8,10-11,13-14,17,19H,3-4,9,15-16H2,1-2H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105503 (US10047086, 71 | US10640503, Example 71 | US969516...) Show SMILES CN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3ccc(nc3)N3CCCC3=O)n3cncc23)C1 |r| Show InChI InChI=1S/C30H30N6O2/c1-34-12-2-4-22(18-34)19-38-27-14-25(23-8-6-21(15-31)7-9-23)30(36-20-32-17-26(27)36)24-10-11-28(33-16-24)35-13-3-5-29(35)37/h6-11,14,16-17,20,22H,2-5,12-13,18-19H2,1H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020) BindingDB Entry DOI: 10.7270/Q2D79FFC
					More data for this Ligand-Target Pair

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