Compile Data Set for Download or QSAR

Found 28 hits with Last Name = 'cueto' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393843 (CHEMBL2159748) Show SMILES O=C(N1CCC[C@H]1C#N)c1cccc2CN(Cc3ccccc3)C(=O)c12 |r| Show InChI InChI=1S/C21H19N3O2/c22-12-17-9-5-11-24(17)20(25)18-10-4-8-16-14-23(21(26)19(16)18)13-15-6-2-1-3-7-15/h1-4,6-8,10,17H,5,9,11,13-14H2/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in human LNZ308 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393843 (CHEMBL2159748) Show SMILES O=C(N1CCC[C@H]1C#N)c1cccc2CN(Cc3ccccc3)C(=O)c12 |r| Show InChI InChI=1S/C21H19N3O2/c22-12-17-9-5-11-24(17)20(25)18-10-4-8-16-14-23(21(26)19(16)18)13-15-6-2-1-3-7-15/h1-4,6-8,10,17H,5,9,11,13-14H2/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in human LN229 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393843 (CHEMBL2159748) Show SMILES O=C(N1CCC[C@H]1C#N)c1cccc2CN(Cc3ccccc3)C(=O)c12 |r| Show InChI InChI=1S/C21H19N3O2/c22-12-17-9-5-11-24(17)20(25)18-10-4-8-16-14-23(21(26)19(16)18)13-15-6-2-1-3-7-15/h1-4,6-8,10,17H,5,9,11,13-14H2/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in human HCEC cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393844 (CHEMBL2159745) Show SMILES O=C(NCc1ccccc1)c1ccccc1C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-6-12-23(16)20(25)18-11-5-4-10-17(18)19(24)22-14-15-7-2-1-3-8-15/h1-5,7-8,10-11,16H,6,9,12,14H2,(H,22,24)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in human HCEC cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393844 (CHEMBL2159745) Show SMILES O=C(NCc1ccccc1)c1ccccc1C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-6-12-23(16)20(25)18-11-5-4-10-17(18)19(24)22-14-15-7-2-1-3-8-15/h1-5,7-8,10-11,16H,6,9,12,14H2,(H,22,24)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in human LN18 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393844 (CHEMBL2159745) Show SMILES O=C(NCc1ccccc1)c1ccccc1C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-6-12-23(16)20(25)18-11-5-4-10-17(18)19(24)22-14-15-7-2-1-3-8-15/h1-5,7-8,10-11,16H,6,9,12,14H2,(H,22,24)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in human LN229 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393844 (CHEMBL2159745) Show SMILES O=C(NCc1ccccc1)c1ccccc1C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-6-12-23(16)20(25)18-11-5-4-10-17(18)19(24)22-14-15-7-2-1-3-8-15/h1-5,7-8,10-11,16H,6,9,12,14H2,(H,22,24)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in human LNZ308 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393843 (CHEMBL2159748) Show SMILES O=C(N1CCC[C@H]1C#N)c1cccc2CN(Cc3ccccc3)C(=O)c12 |r| Show InChI InChI=1S/C21H19N3O2/c22-12-17-9-5-11-24(17)20(25)18-10-4-8-16-14-23(21(26)19(16)18)13-15-6-2-1-3-7-15/h1-4,6-8,10,17H,5,9,11,13-14H2/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in human LN18 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393842 (CHEMBL2159749) Show SMILES O=C(N1CCCC1)c1cccc2CN(Cc3ccccc3)C(=O)c12 Show InChI InChI=1S/C20H20N2O2/c23-19(21-11-4-5-12-21)17-10-6-9-16-14-22(20(24)18(16)17)13-15-7-2-1-3-8-15/h1-3,6-10H,4-5,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition at human recombinant POP				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393843 (CHEMBL2159748) Show SMILES O=C(N1CCC[C@H]1C#N)c1cccc2CN(Cc3ccccc3)C(=O)c12 |r| Show InChI InChI=1S/C21H19N3O2/c22-12-17-9-5-11-24(17)20(25)18-10-4-8-16-14-23(21(26)19(16)18)13-15-6-2-1-3-7-15/h1-4,6-8,10,17H,5,9,11,13-14H2/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in intact human LNZ308 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393844 (CHEMBL2159745) Show SMILES O=C(NCc1ccccc1)c1ccccc1C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-6-12-23(16)20(25)18-11-5-4-10-17(18)19(24)22-14-15-7-2-1-3-8-15/h1-5,7-8,10-11,16H,6,9,12,14H2,(H,22,24)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in intact human LN18 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393844 (CHEMBL2159745) Show SMILES O=C(NCc1ccccc1)c1ccccc1C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-6-12-23(16)20(25)18-11-5-4-10-17(18)19(24)22-14-15-7-2-1-3-8-15/h1-5,7-8,10-11,16H,6,9,12,14H2,(H,22,24)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in intact human HCEC cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393844 (CHEMBL2159745) Show SMILES O=C(NCc1ccccc1)c1ccccc1C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-6-12-23(16)20(25)18-11-5-4-10-17(18)19(24)22-14-15-7-2-1-3-8-15/h1-5,7-8,10-11,16H,6,9,12,14H2,(H,22,24)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in intact human LNZ308 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393843 (CHEMBL2159748) Show SMILES O=C(N1CCC[C@H]1C#N)c1cccc2CN(Cc3ccccc3)C(=O)c12 |r| Show InChI InChI=1S/C21H19N3O2/c22-12-17-9-5-11-24(17)20(25)18-10-4-8-16-14-23(21(26)19(16)18)13-15-6-2-1-3-7-15/h1-4,6-8,10,17H,5,9,11,13-14H2/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in intact human LN18 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393842 (CHEMBL2159749) Show SMILES O=C(N1CCCC1)c1cccc2CN(Cc3ccccc3)C(=O)c12 Show InChI InChI=1S/C20H20N2O2/c23-19(21-11-4-5-12-21)17-10-6-9-16-14-22(20(24)18(16)17)13-15-7-2-1-3-8-15/h1-3,6-10H,4-5,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in human LNZ308 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393843 (CHEMBL2159748) Show SMILES O=C(N1CCC[C@H]1C#N)c1cccc2CN(Cc3ccccc3)C(=O)c12 |r| Show InChI InChI=1S/C21H19N3O2/c22-12-17-9-5-11-24(17)20(25)18-10-4-8-16-14-23(21(26)19(16)18)13-15-6-2-1-3-7-15/h1-4,6-8,10,17H,5,9,11,13-14H2/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in intact human LN229 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393844 (CHEMBL2159745) Show SMILES O=C(NCc1ccccc1)c1ccccc1C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-6-12-23(16)20(25)18-11-5-4-10-17(18)19(24)22-14-15-7-2-1-3-8-15/h1-5,7-8,10-11,16H,6,9,12,14H2,(H,22,24)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in intact human LN229 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393843 (CHEMBL2159748) Show SMILES O=C(N1CCC[C@H]1C#N)c1cccc2CN(Cc3ccccc3)C(=O)c12 |r| Show InChI InChI=1S/C21H19N3O2/c22-12-17-9-5-11-24(17)20(25)18-10-4-8-16-14-23(21(26)19(16)18)13-15-6-2-1-3-7-15/h1-4,6-8,10,17H,5,9,11,13-14H2/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in intact human HCEC cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393842 (CHEMBL2159749) Show SMILES O=C(N1CCCC1)c1cccc2CN(Cc3ccccc3)C(=O)c12 Show InChI InChI=1S/C20H20N2O2/c23-19(21-11-4-5-12-21)17-10-6-9-16-14-22(20(24)18(16)17)13-15-7-2-1-3-8-15/h1-3,6-10H,4-5,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in human LN229 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393842 (CHEMBL2159749) Show SMILES O=C(N1CCCC1)c1cccc2CN(Cc3ccccc3)C(=O)c12 Show InChI InChI=1S/C20H20N2O2/c23-19(21-11-4-5-12-21)17-10-6-9-16-14-22(20(24)18(16)17)13-15-7-2-1-3-8-15/h1-3,6-10H,4-5,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in intact human LN18 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393842 (CHEMBL2159749) Show SMILES O=C(N1CCCC1)c1cccc2CN(Cc3ccccc3)C(=O)c12 Show InChI InChI=1S/C20H20N2O2/c23-19(21-11-4-5-12-21)17-10-6-9-16-14-22(20(24)18(16)17)13-15-7-2-1-3-8-15/h1-3,6-10H,4-5,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in intact human LN229 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393842 (CHEMBL2159749) Show SMILES O=C(N1CCCC1)c1cccc2CN(Cc3ccccc3)C(=O)c12 Show InChI InChI=1S/C20H20N2O2/c23-19(21-11-4-5-12-21)17-10-6-9-16-14-22(20(24)18(16)17)13-15-7-2-1-3-8-15/h1-3,6-10H,4-5,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in human LN18 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393842 (CHEMBL2159749) Show SMILES O=C(N1CCCC1)c1cccc2CN(Cc3ccccc3)C(=O)c12 Show InChI InChI=1S/C20H20N2O2/c23-19(21-11-4-5-12-21)17-10-6-9-16-14-22(20(24)18(16)17)13-15-7-2-1-3-8-15/h1-3,6-10H,4-5,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in human HCEC cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393842 (CHEMBL2159749) Show SMILES O=C(N1CCCC1)c1cccc2CN(Cc3ccccc3)C(=O)c12 Show InChI InChI=1S/C20H20N2O2/c23-19(21-11-4-5-12-21)17-10-6-9-16-14-22(20(24)18(16)17)13-15-7-2-1-3-8-15/h1-3,6-10H,4-5,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in intact human LNZ308 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50393842 (CHEMBL2159749) Show SMILES O=C(N1CCCC1)c1cccc2CN(Cc3ccccc3)C(=O)c12 Show InChI InChI=1S/C20H20N2O2/c23-19(21-11-4-5-12-21)17-10-6-9-16-14-22(20(24)18(16)17)13-15-7-2-1-3-8-15/h1-3,6-10H,4-5,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of POP in intact human HCEC cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assay				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Homo sapiens (Human))	BDBM50393843 (CHEMBL2159748) Show SMILES O=C(N1CCC[C@H]1C#N)c1cccc2CN(Cc3ccccc3)C(=O)c12 |r| Show InChI InChI=1S/C21H19N3O2/c22-12-17-9-5-11-24(17)20(25)18-10-4-8-16-14-23(21(26)19(16)18)13-15-6-2-1-3-7-15/h1-4,6-8,10,17H,5,9,11,13-14H2/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition at human recombinant FAPalpha				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Homo sapiens (Human))	BDBM50393842 (CHEMBL2159749) Show SMILES O=C(N1CCCC1)c1cccc2CN(Cc3ccccc3)C(=O)c12 Show InChI InChI=1S/C20H20N2O2/c23-19(21-11-4-5-12-21)17-10-6-9-16-14-22(20(24)18(16)17)13-15-7-2-1-3-8-15/h1-3,6-10H,4-5,11-14H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition at human recombinant FAPalpha				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Homo sapiens (Human))	BDBM50393844 (CHEMBL2159745) Show SMILES O=C(NCc1ccccc1)c1ccccc1C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-6-12-23(16)20(25)18-11-5-4-10-17(18)19(24)22-14-15-7-2-1-3-8-15/h1-5,7-8,10-11,16H,6,9,12,14H2,(H,22,24)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition at human recombinant FAPalpha				J Med Chem 55: 6306-15 (2012) Article DOI: 10.1021/jm3002839 BindingDB Entry DOI: 10.7270/Q2D79CHF
					More data for this Ligand-Target Pair