Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 2 (MOUSE) | BDBM50370617![]() (CHEMBL1791313 | CHEMBL1791314) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t M£nchen Curated by ChEMBL | Assay Description Inhibition of [125I][Leu8,D-Trp22,Trp25]somatostatin-28 binding to somatostatin receptor 2 | J Med Chem 48: 1506-14 (2005) Article DOI: 10.1021/jm0496335 BindingDB Entry DOI: 10.7270/Q2FF3T40 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (MOUSE) | BDBM50370617![]() (CHEMBL1791313 | CHEMBL1791314) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t M£nchen Curated by ChEMBL | Assay Description Inhibition of [125I][Leu8,D-Trp22,Trp25]somatostatin-28 binding to somatostatin receptor 2 | J Med Chem 48: 1506-14 (2005) Article DOI: 10.1021/jm0496335 BindingDB Entry DOI: 10.7270/Q2FF3T40 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448369![]() (Perampanel, 21) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448371![]() (Perampanel, 23) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448366![]() (Perampanel, 18 | Perampanel, 19) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448373![]() (Perampanel, 25) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476986![]() (Inhibitor 17 of SARS-CoV-2 Mpro | Inhibitor 7 of S...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476992![]() (Inhibitor 12 of SARS-CoV-2 Mpro | US20240092759, C...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476998![]() (Inhibitor 18 of SARS-CoV-2 Mpro | US20240092759, C...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448370![]() (Perampanel, 22) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448368![]() (Perampanel, 20) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476984![]() (Inhibitor 16 of SARS-CoV-2 Mpro | Inhibitor 6 of S...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448366![]() (Perampanel, 18 | Perampanel, 19) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448372![]() (Perampanel, 24) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476995![]() (Inhibitor 15 of SARS-CoV-2 Mpro) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476993![]() (Inhibitor 13 of SARS-CoV-2 Mpro) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476999![]() (Inhibitor 19 of SARS-CoV-2 Mpro) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM484209![]() (Inhibitor 17 of SARS-CoV-2 Mpro) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM484208![]() (Inhibitor 16 of SARS-CoV-2 Mpro) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM484213![]() (Inhibitor 21 of SARS-CoV-2 Mpro) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476988![]() (Inhibitor 9 of SARS-CoV-2 Mpro) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476990![]() (Inhibitor 10 of SARS-CoV-2 Mpro | US20240092759, C...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448363![]() (Perampanel, 16) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476994![]() (Inhibitor 14 of SARS-CoV-2 Mpro) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448362![]() (Perampanel, 15) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448364![]() (Perampanel, 17) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448375![]() (Perampanel, 27) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448357![]() (Perampanel, 11) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476982![]() (Inhibitor 5 of SARS-CoV-2 Mpro | US20240092759, Co...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476981![]() (Inhibitor 4 of SARS-CoV-2 Mpro | US20240092759, Co...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448361![]() (Perampanel, 14) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM484212![]() (Inhibitor 20 of SARS-CoV-2 Mpro) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476991![]() (Inhibitor 11 of SARS-CoV-2 Mpro) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 131 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448349![]() (Perampanel, 5) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476977![]() (Inhibitor 2 of SARS-CoV-2 Mpro | US20240092759, Co...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448374![]() (Perampanel, 26) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476978![]() (Inhibitor 3 of SARS-CoV-2 Mpro | US20240092759, Co...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448359![]() (Perampanel, 13) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448358![]() (Perampanel, 12) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448351![]() (Perampanel, 7) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM476987![]() (Inhibitor 8 of SARS-CoV-2 Mpro) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 328 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448350![]() (Perampanel, 6) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448353![]() (Perampanel, 8) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448355![]() (Perampanel, 10) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448348![]() (Perampanel, 4) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 4.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448354![]() (Perampanel, 9) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448347![]() (Perampanel, 3) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 6.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM448335![]() (Perampanel, 2) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article | n/a | n/a | 9.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM50184410![]() (CHEBI:71013 | E-2007 | E2007 | ER-155055-90 | Fyco...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | 1.75E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the... | ACS Cent Sci (2021) Article DOI: 10.1021/acscentsci.1c00039 BindingDB Entry DOI: 10.7270/Q20K2CMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Replicase polyprotein 1ab (2019-nCoV) | BDBM50184410![]() (CHEBI:71013 | E-2007 | E2007 | ER-155055-90 | Fyco...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.75E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University | Assay Description Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif... | ACS Med Chem Lett 12: 1325-1332 (2021) Article DOI: 10.1021/acsmedchemlett.1c00326 BindingDB Entry DOI: 10.7270/Q24J0J74 | |||||||||||
More data for this Ligand-Target Pair |
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