Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteasome assembly chaperone 3 (Homo sapiens (Human)) | BDBM50520988![]() (CHEMBL4435319) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku University Curated by ChEMBL | Assay Description Inhibition of PAC3 homodimer (unknown origin) protein-protein interaction | Bioorg Med Chem 26: 6023-6034 (2018) Article DOI: 10.1016/j.bmc.2018.11.001 BindingDB Entry DOI: 10.7270/Q24X5C69 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome assembly chaperone 3 (Homo sapiens (Human)) | BDBM50316413![]() ((S)-2-hydroxy-2-(((S,E)-4-(hydroxy((1R,2R,4aS,8aR)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Biomedicinal Information Research Center (BIRC) Curated by ChEMBL | Assay Description Inhibition of PAC3 homodimerization by protein fragment complementation assay | J Nat Prod 73: 628-31 (2010) Article DOI: 10.1021/np900788e BindingDB Entry DOI: 10.7270/Q2M61KD2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50384889![]() (CHEMBL2036061) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Biomedicinal Information Research Center (BIRC) Curated by ChEMBL | Assay Description Inhibition of human Tdp1 using 3'-phosphate-(4-methylumbelliferone)-thymidine as substrate after 180 mins by spectrophotometry | J Nat Prod 75: 764-7 (2012) Article DOI: 10.1021/np2007389 BindingDB Entry DOI: 10.7270/Q2V9893K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome assembly chaperone 3 (Homo sapiens (Human)) | BDBM50520987![]() (CHEMBL4447106) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku University Curated by ChEMBL | Assay Description Inhibition of PAC3 homodimer (unknown origin) protein-protein interaction | Bioorg Med Chem 26: 6023-6034 (2018) Article DOI: 10.1016/j.bmc.2018.11.001 BindingDB Entry DOI: 10.7270/Q24X5C69 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome assembly chaperone 1/2 (Homo sapiens) | BDBM50520988![]() (CHEMBL4435319) | MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku University Curated by ChEMBL | Assay Description Inhibition of PAC1/PAC2 heterodimer (unknown origin) protein-protein interaction | Bioorg Med Chem 26: 6023-6034 (2018) Article DOI: 10.1016/j.bmc.2018.11.001 BindingDB Entry DOI: 10.7270/Q24X5C69 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome assembly chaperone 3 (Homo sapiens (Human)) | BDBM50520986![]() (CHEMBL4466606) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku University Curated by ChEMBL | Assay Description Inhibition of PAC3 homodimer (unknown origin) protein-protein interaction | Bioorg Med Chem 26: 6023-6034 (2018) Article DOI: 10.1016/j.bmc.2018.11.001 BindingDB Entry DOI: 10.7270/Q24X5C69 | |||||||||||
More data for this Ligand-Target Pair |