Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ephrin type-A receptor 2 (Homo sapiens (Human)) | BDBM50551201 (CHEMBL4761556) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of biotinylated ephrin-A1-Fc binding to EphA2 (unknown origin) | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Homo sapiens (Human)) | BDBM50234957 (CHEMBL3735125) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of biotinylated ephrin-A1-Fc binding to EphA2 (unknown origin) | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Homo sapiens (Human)) | BDBM50234948 (CHEMBL4078429) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of biotinylated ephrin-A1-Fc binding to EphA2 (unknown origin) | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Homo sapiens (Human)) | BDBM50234950 (CHEMBL4059908) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Parma Curated by ChEMBL | Assay Description Binding affinity to EphA2 (unknown origin) | Eur J Med Chem 142: 152-162 (2017) Article DOI: 10.1016/j.ejmech.2017.07.029 BindingDB Entry DOI: 10.7270/Q29026GX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50234948 (CHEMBL4078429) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse EphA2 receptor preincubated for 1 hr followed by biotinylated ephrin-A1-Fc addition ... | J Med Chem 60: 787-796 (2017) Article DOI: 10.1021/acs.jmedchem.6b01642 BindingDB Entry DOI: 10.7270/Q2R78HHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50234948 (CHEMBL4078429) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse EphA2 receptor preincubated for 1 hr followed by biotinylated ephrin-A1-Fc addition ... | J Med Chem 60: 787-796 (2017) Article DOI: 10.1021/acs.jmedchem.6b01642 BindingDB Entry DOI: 10.7270/Q2R78HHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50234957 (CHEMBL3735125) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse EphA2 receptor preincubated for 1 hr followed by biotinylated ephrin-A1-Fc addition ... | J Med Chem 60: 787-796 (2017) Article DOI: 10.1021/acs.jmedchem.6b01642 BindingDB Entry DOI: 10.7270/Q2R78HHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50234957 (CHEMBL3735125) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 912 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse EphA2 receptor preincubated for 1 hr followed by biotinylated ephrin-A1-Fc addition ... | J Med Chem 60: 787-796 (2017) Article DOI: 10.1021/acs.jmedchem.6b01642 BindingDB Entry DOI: 10.7270/Q2R78HHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50551201 (CHEMBL4761556) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50551202 (CHEMBL4780052) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50551206 (CHEMBL4761852) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50234948 (CHEMBL4078429) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 8 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-A1-Fc from EphA8 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50551203 (CHEMBL4756215) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 6 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-A1-Fc from EphA6 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Homo sapiens (Human)) | BDBM50551201 (CHEMBL4761556) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at EphA2-Fc in human PC3 cells assessed as reduction in ephrin-A1-Fc stimulated EphA2 phosphorylation preincubated for 20 mins fo... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50234952 (CHEMBL4079387) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse EphA2 receptor preincubated for 1 hr followed by biotinylated ephrin-A1-Fc addition ... | J Med Chem 60: 787-796 (2017) Article DOI: 10.1021/acs.jmedchem.6b01642 BindingDB Entry DOI: 10.7270/Q2R78HHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50234952 (CHEMBL4079387) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse EphA2 receptor preincubated for 1 hr followed by biotinylated ephrin-A1-Fc addition ... | J Med Chem 60: 787-796 (2017) Article DOI: 10.1021/acs.jmedchem.6b01642 BindingDB Entry DOI: 10.7270/Q2R78HHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of ephrin-A1-Fc binding to EphA2-Fc receptor (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 6 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-A1-Fc from EphA7 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-A1-Fc from EphA2 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 1 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-A1-Fc from EphA1 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 5 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-A1-Fc from EphA5 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 3 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-A1-Fc from EphA3 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50551198 (CHEMBL4783384) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 4 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-A1-Fc from EphA4 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-B receptor 4 (Homo sapiens (Human)) | BDBM50134791 (CHEMBL3734863) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of biotinylated ephrin-B1-Fc from EphB4 (unknown origin) preincubated for 1 hr followed by biotinylated-ephrin-B1-Fc addition measured a... | Eur J Med Chem 103: 312-24 (2015) Article DOI: 10.1016/j.ejmech.2015.08.048 BindingDB Entry DOI: 10.7270/Q2KW5HWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50234949 (CHEMBL4087778) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse EphA2 receptor preincubated for 1 hr followed by biotinylated ephrin-A1-Fc addition ... | J Med Chem 60: 787-796 (2017) Article DOI: 10.1021/acs.jmedchem.6b01642 BindingDB Entry DOI: 10.7270/Q2R78HHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50551195 (CHEMBL4795158) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Homo sapiens (Human)) | BDBM50551202 (CHEMBL4780052) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at EphA2-Fc in human PC3 cells assessed as reduction in ephrin-A1-Fc stimulated EphA2 phosphorylation preincubated for 20 mins fo... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50551194 (CHEMBL4763613) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-B receptor 2 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-B1-Fc from EphB2 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-B receptor 1 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-B1-Fc from EphB1 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50234954 (CHEMBL4089696) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse EphA2 receptor preincubated for 1 hr followed by biotinylated ephrin-A1-Fc addition ... | J Med Chem 60: 787-796 (2017) Article DOI: 10.1021/acs.jmedchem.6b01642 BindingDB Entry DOI: 10.7270/Q2R78HHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-B receptor 3 (Homo sapiens (Human)) | BDBM50134791 (CHEMBL3734863) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of biotinylated ephrin-B1-Fc from EphB3 (unknown origin) preincubated for 1 hr followed by biotinylated-ephrin-B1-Fc addition measured a... | Eur J Med Chem 103: 312-24 (2015) Article DOI: 10.1016/j.ejmech.2015.08.048 BindingDB Entry DOI: 10.7270/Q2KW5HWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Homo sapiens (Human)) | BDBM50551203 (CHEMBL4756215) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at EphA2-Fc in human PC3 cells assessed as reduction in ephrin-A1-Fc stimulated EphA2 phosphorylation preincubated for 20 mins fo... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 5 (Rattus norvegicus) | BDBM50551201 (CHEMBL4761556) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from rat EphA5 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELISA | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-B receptor 3 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-B1-Fc from EphB3 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-B receptor 4 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-B1-Fc from EphB4 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50551196 (CHEMBL4776034) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 3 (Mus musculus) | BDBM50551201 (CHEMBL4761556) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from mouse EphA3 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Antagonist activity at EphA2 receptor in human PC3 cells assessed as inhibition of ephrin-A1-Fc-stimulated cell retraction pretreated for 15 mins by ... | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50551200 (CHEMBL4746495) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50551207 (CHEMBL4742817) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-B receptor 6 (Homo sapiens (Human)) | BDBM50428059 (CHEMBL2322989) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Displacement of ephrin-B1-Fc from EphB6 receptor Fc ectodomain (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Homo sapiens (Human)) | BDBM50234948 (CHEMBL4078429) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at EphA2-Fc in human PC3 cells assessed as reduction in ephrin-A1-Fc stimulated EphA2 phosphorylation preincubated for 20 mins fo... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 4 (Mus musculus) | BDBM50551201 (CHEMBL4761556) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from mouse EphA4 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Mus musculus) | BDBM50551205 (CHEMBL4776886) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from recombinant mouse c-terminal His6-tagged EphA2 Fc (Ala22 to Ala535 residues) preincubated for 1 hr fol... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 2 (Homo sapiens (Human)) | BDBM50027867 (CHEMBL2323555) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of ephrin-A1-Fc binding to EphA2-Fc receptor (unknown origin) after 1 hr by ELISA | J Med Chem 56: 2936-47 (2013) Article DOI: 10.1021/jm301890k BindingDB Entry DOI: 10.7270/Q2JW8G7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 8 (Mus musculus) | BDBM50551201 (CHEMBL4761556) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of biotinylated ephrin-A1-Fc from mouse EphA8 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112083 BindingDB Entry DOI: 10.7270/Q2X35233 | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 118 total ) | Next | Last >> |