Found 353 hits with Last Name = 'hossain' and Initial = 'ma' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558038
(CHEMBL4798311)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@@H]2NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(C)C)C(C)C)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558038
(CHEMBL4798311)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@@H]2NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(C)C)C(C)C)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558042
(CHEMBL4760798)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@@H]2NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558042
(CHEMBL4760798)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@@H]2NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558040
(CHEMBL4791094)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(C)C)C(C)C)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558040
(CHEMBL4791094)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(C)C)C(C)C)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558043
(CHEMBL4742346)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558043
(CHEMBL4742346)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558044
(CHEMBL4796474)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558044
(CHEMBL4796474)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50547989
(CHEMBL4747872)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50547989
(CHEMBL4747872)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558039
(CHEMBL4752265)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@@H]2NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC2=O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC1=O)[C@@H](C)O)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)C1CCC(=O)N1)[C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558039
(CHEMBL4752265)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@@H]2NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC2=O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC1=O)[C@@H](C)O)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)C1CCC(=O)N1)[C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50547990
(CHEMBL4799795)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@@H](N)CO)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Competitive binding affinity to human RXFP4 receptor transfected in CHO-K1 cells in presence of europium-labeled Eu(A)-R3/I5 by fluorometric analysis |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00435
BindingDB Entry DOI: 10.7270/Q20Z76W2 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50547989
(CHEMBL4747872)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Competitive binding affinity to human RXFP4 receptor transfected in CHO-K1 cells in presence of europium-labeled Eu(A)-R3/I5 by fluorometric analysis |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00435
BindingDB Entry DOI: 10.7270/Q20Z76W2 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50561918
(CHEMBL4761849)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of Eu-labeled H3B1-22R from RXFP3 (unknown origin) stably expressed in CHO-K1 cells by competition binding assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00456
BindingDB Entry DOI: 10.7270/Q2G73JFZ |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50547991
(CHEMBL4740938)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCCNC(N)=N)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Competitive binding affinity to human RXFP4 receptor transfected in CHO-K1 cells in presence of europium-labeled Eu(A)-R3/I5 by fluorometric analysis |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00435
BindingDB Entry DOI: 10.7270/Q20Z76W2 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50534445
(CHEMBL4476408)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@]1(C)CCC\C=C\CCC[C@](C)(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CN)C(C)C)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,t:17| Show InChI InChI=1S/C116H185N35O27/c1-14-65(9)90-105(172)138-76(43-33-49-129-114(124)125)102(169)151-116(13,45-29-19-17-16-18-28-44-115(12,109(177)144-79(99(166)146-90)52-69-36-24-21-25-37-69)150-101(168)75(42-32-48-128-113(122)123)134-87(159)58-133-93(160)81(59-152)142-97(164)77(50-62(3)4)139-95(162)74(41-31-47-127-112(120)121)137-103(170)88(63(5)6)145-84(156)54-117)110(178)149-89(64(7)8)104(171)147-91(66(10)15-2)106(173)140-78(51-68-34-22-20-23-35-68)98(165)148-92(67(11)155)107(174)143-82(60-153)94(161)132-56-85(157)131-57-86(158)135-83(61-154)100(167)136-73(40-30-46-126-111(118)119)96(163)141-80(108(175)176)53-70-55-130-72-39-27-26-38-71(70)72/h16-17,20-27,34-39,55,62-67,73-83,88-92,130,152-155H,14-15,18-19,28-33,40-54,56-61,117H2,1-13H3,(H,131,157)(H,132,161)(H,133,160)(H,134,159)(H,135,158)(H,136,167)(H,137,170)(H,138,172)(H,139,162)(H,140,173)(H,141,163)(H,142,164)(H,143,174)(H,144,177)(H,145,156)(H,146,166)(H,147,171)(H,148,165)(H,149,178)(H,150,168)(H,151,169)(H,175,176)(H4,118,119,126)(H4,120,121,127)(H4,122,123,128)(H4,124,125,129)/b17-16+/t65-,66-,67+,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,88-,89-,90-,91-,92-,115-,116-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-H3/15 from human RXFP3 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50534442
(CHEMBL4438620)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@]1(C)CCC\C=C\CCC[C@](C)(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,t:17| Show InChI InChI=1S/C111H175N33O26/c1-13-62(7)86-100(164)132-74(42-32-48-123-109(118)119)98(162)144-111(12,44-28-18-16-15-17-27-43-110(11,104(169)138-77(95(159)139-86)51-67-35-23-20-24-36-67)143-97(161)73(41-31-47-122-108(116)117)129-84(152)56-127-89(153)79(57-145)136-93(157)75(49-60(3)4)133-91(155)71(128-65(10)149)39-29-45-120-106(112)113)105(170)142-85(61(5)6)99(163)140-87(63(8)14-2)101(165)134-76(50-66-33-21-19-22-34-66)94(158)141-88(64(9)148)102(166)137-80(58-146)90(154)126-54-82(150)125-55-83(151)130-81(59-147)96(160)131-72(40-30-46-121-107(114)115)92(156)135-78(103(167)168)52-68-53-124-70-38-26-25-37-69(68)70/h15-16,19-26,33-38,53,60-64,71-81,85-88,124,145-148H,13-14,17-18,27-32,39-52,54-59H2,1-12H3,(H,125,150)(H,126,154)(H,127,153)(H,128,149)(H,129,152)(H,130,151)(H,131,160)(H,132,164)(H,133,155)(H,134,165)(H,135,156)(H,136,157)(H,137,166)(H,138,169)(H,139,159)(H,140,163)(H,141,158)(H,142,170)(H,143,161)(H,144,162)(H,167,168)(H4,112,113,120)(H4,114,115,121)(H4,116,117,122)(H4,118,119,123)/b16-15+/t62-,63-,64+,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,85-,86-,87-,88-,110-,111-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 107 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-H3/15 from human RXFP3 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50534454
(CHEMBL4540069)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@]1(C)CCC\C=C\CCC[C@](C)(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,t:17| Show InChI InChI=1S/C109H173N33O25/c1-12-61(7)84-98(161)130-72(41-31-47-122-107(117)118)96(159)142-109(11,43-27-17-15-14-16-26-42-108(10,102(166)136-75(93(156)137-84)50-65-34-22-19-23-35-65)141-95(158)71(40-30-46-121-106(115)116)127-82(149)55-126-88(151)77(56-143)134-91(154)73(48-59(3)4)131-87(150)68(110)37-28-44-119-104(111)112)103(167)140-83(60(5)6)97(160)138-85(62(8)13-2)99(162)132-74(49-64-32-20-18-21-33-64)92(155)139-86(63(9)146)100(163)135-78(57-144)89(152)125-53-80(147)124-54-81(148)128-79(58-145)94(157)129-70(39-29-45-120-105(113)114)90(153)133-76(101(164)165)51-66-52-123-69-38-25-24-36-67(66)69/h14-15,18-25,32-36,38,52,59-63,68,70-79,83-86,123,143-146H,12-13,16-17,26-31,37,39-51,53-58,110H2,1-11H3,(H,124,147)(H,125,152)(H,126,151)(H,127,149)(H,128,148)(H,129,157)(H,130,161)(H,131,150)(H,132,162)(H,133,153)(H,134,154)(H,135,163)(H,136,166)(H,137,156)(H,138,160)(H,139,155)(H,140,167)(H,141,158)(H,142,159)(H,164,165)(H4,111,112,119)(H4,113,114,120)(H4,115,116,121)(H4,117,118,122)/b15-14+/t61-,62-,63+,68-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,83-,84-,85-,86-,108-,109-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-H3/15 from human RXFP3 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50561920
(CHEMBL4764969)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)N[C@H](COC(N)=O)Cc1c[nH]c2ccccc12)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of Eu-labeled H3B1-22R from RXFP3 (unknown origin) stably expressed in CHO-K1 cells by competition binding assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00456
BindingDB Entry DOI: 10.7270/Q2G73JFZ |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50534442
(CHEMBL4438620)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@]1(C)CCC\C=C\CCC[C@](C)(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,t:17| Show InChI InChI=1S/C111H175N33O26/c1-13-62(7)86-100(164)132-74(42-32-48-123-109(118)119)98(162)144-111(12,44-28-18-16-15-17-27-43-110(11,104(169)138-77(95(159)139-86)51-67-35-23-20-24-36-67)143-97(161)73(41-31-47-122-108(116)117)129-84(152)56-127-89(153)79(57-145)136-93(157)75(49-60(3)4)133-91(155)71(128-65(10)149)39-29-45-120-106(112)113)105(170)142-85(61(5)6)99(163)140-87(63(8)14-2)101(165)134-76(50-66-33-21-19-22-34-66)94(158)141-88(64(9)148)102(166)137-80(58-146)90(154)126-54-82(150)125-55-83(151)130-81(59-147)96(160)131-72(40-30-46-121-107(114)115)92(156)135-78(103(167)168)52-68-53-124-70-38-26-25-37-69(68)70/h15-16,19-26,33-38,53,60-64,71-81,85-88,124,145-148H,13-14,17-18,27-32,39-52,54-59H2,1-12H3,(H,125,150)(H,126,154)(H,127,153)(H,128,149)(H,129,152)(H,130,151)(H,131,160)(H,132,164)(H,133,155)(H,134,165)(H,135,156)(H,136,157)(H,137,166)(H,138,169)(H,139,159)(H,140,163)(H,141,158)(H,142,170)(H,143,161)(H,144,162)(H,167,168)(H4,112,113,120)(H4,114,115,121)(H4,116,117,122)(H4,118,119,123)/b16-15+/t62-,63-,64+,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,85-,86-,87-,88-,110-,111-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 123 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-INSL5 from human RXFP4 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558041
(CHEMBL4783899)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 145 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558041
(CHEMBL4783899)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 145 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50534448
(CHEMBL4435599)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@]1(C)CCC\C=C\CCC[C@](C)(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](N)CO)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,t:17| Show InChI InChI=1S/C97H150N28O23/c1-10-54(5)75-87(142)115-65(37-28-42-107-95(103)104)85(140)125-97(9,39-25-15-13-12-14-24-38-96(8,91(147)119-67(82(137)120-75)44-58-31-20-17-21-32-58)124-84(139)64(36-27-41-106-94(101)102)112-73(132)49-110-78(133)61(98)50-126)92(148)123-74(53(3)4)86(141)121-76(55(6)11-2)88(143)116-66(43-57-29-18-16-19-30-57)81(136)122-77(56(7)129)89(144)118-69(51-127)79(134)111-47-71(130)109-48-72(131)113-70(52-128)83(138)114-63(35-26-40-105-93(99)100)80(135)117-68(90(145)146)45-59-46-108-62-34-23-22-33-60(59)62/h12-13,16-23,29-34,46,53-56,61,63-70,74-77,108,126-129H,10-11,14-15,24-28,35-45,47-52,98H2,1-9H3,(H,109,130)(H,110,133)(H,111,134)(H,112,132)(H,113,131)(H,114,138)(H,115,142)(H,116,143)(H,117,135)(H,118,144)(H,119,147)(H,120,137)(H,121,141)(H,122,136)(H,123,148)(H,124,139)(H,125,140)(H,145,146)(H4,99,100,105)(H4,101,102,106)(H4,103,104,107)/b13-12+/t54-,55-,56+,61-,63-,64-,65-,66-,67-,68-,69-,70-,74-,75-,76-,77-,96-,97-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 151 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-H3/15 from human RXFP3 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50561919
(CHEMBL4781389)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OC[C@H](NC(C)=O)C(N)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 186 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of Eu-labeled H3B1-22R from RXFP3 (unknown origin) stably expressed in CHO-K1 cells by competition binding assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00456
BindingDB Entry DOI: 10.7270/Q2G73JFZ |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50561922
(CHEMBL4799017)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 191 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of Eu-labeled H3B1-22R from RXFP3 (unknown origin) stably expressed in CHO-K1 cells by competition binding assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00456
BindingDB Entry DOI: 10.7270/Q2G73JFZ |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50534443
(CHEMBL4447532)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@]1(C)CCC\C=C\CCC[C@](C)(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CNC(C)=O)C(C)C)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,t:17| Show InChI InChI=1S/C118H187N35O28/c1-15-66(9)92-107(175)140-78(44-34-50-130-116(125)126)104(172)153-118(14,46-30-20-18-17-19-29-45-117(13,111(180)146-81(101(169)148-92)53-71-37-25-22-26-38-71)152-103(171)77(43-33-49-129-115(123)124)136-88(161)59-135-95(163)83(60-154)144-99(167)79(51-63(3)4)141-97(165)76(42-32-48-128-114(121)122)139-105(173)90(64(5)6)147-89(162)57-131-69(12)158)112(181)151-91(65(7)8)106(174)149-93(67(10)16-2)108(176)142-80(52-70-35-23-21-24-36-70)100(168)150-94(68(11)157)109(177)145-84(61-155)96(164)134-56-86(159)133-58-87(160)137-85(62-156)102(170)138-75(41-31-47-127-113(119)120)98(166)143-82(110(178)179)54-72-55-132-74-40-28-27-39-73(72)74/h17-18,21-28,35-40,55,63-68,75-85,90-94,132,154-157H,15-16,19-20,29-34,41-54,56-62H2,1-14H3,(H,131,158)(H,133,159)(H,134,164)(H,135,163)(H,136,161)(H,137,160)(H,138,170)(H,139,173)(H,140,175)(H,141,165)(H,142,176)(H,143,166)(H,144,167)(H,145,177)(H,146,180)(H,147,162)(H,148,169)(H,149,174)(H,150,168)(H,151,181)(H,152,171)(H,153,172)(H,178,179)(H4,119,120,127)(H4,121,122,128)(H4,123,124,129)(H4,125,126,130)/b18-17+/t66-,67-,68+,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,90-,91-,92-,93-,94-,117-,118-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 229 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-H3/15 from human RXFP3 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50534445
(CHEMBL4476408)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@]1(C)CCC\C=C\CCC[C@](C)(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CN)C(C)C)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,t:17| Show InChI InChI=1S/C116H185N35O27/c1-14-65(9)90-105(172)138-76(43-33-49-129-114(124)125)102(169)151-116(13,45-29-19-17-16-18-28-44-115(12,109(177)144-79(99(166)146-90)52-69-36-24-21-25-37-69)150-101(168)75(42-32-48-128-113(122)123)134-87(159)58-133-93(160)81(59-152)142-97(164)77(50-62(3)4)139-95(162)74(41-31-47-127-112(120)121)137-103(170)88(63(5)6)145-84(156)54-117)110(178)149-89(64(7)8)104(171)147-91(66(10)15-2)106(173)140-78(51-68-34-22-20-23-35-68)98(165)148-92(67(11)155)107(174)143-82(60-153)94(161)132-56-85(157)131-57-86(158)135-83(61-154)100(167)136-73(40-30-46-126-111(118)119)96(163)141-80(108(175)176)53-70-55-130-72-39-27-26-38-71(70)72/h16-17,20-27,34-39,55,62-67,73-83,88-92,130,152-155H,14-15,18-19,28-33,40-54,56-61,117H2,1-13H3,(H,131,157)(H,132,161)(H,133,160)(H,134,159)(H,135,158)(H,136,167)(H,137,170)(H,138,172)(H,139,162)(H,140,173)(H,141,163)(H,142,164)(H,143,174)(H,144,177)(H,145,156)(H,146,166)(H,147,171)(H,148,165)(H,149,178)(H,150,168)(H,151,169)(H,175,176)(H4,118,119,126)(H4,120,121,127)(H4,122,123,128)(H4,124,125,129)/b17-16+/t65-,66-,67+,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,88-,89-,90-,91-,92-,115-,116-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 275 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-INSL5 from human RXFP4 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50534453
(CHEMBL4557279)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@]1(C)CCC\C=C\CCC[C@](C)(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,t:17| Show InChI InChI=1S/C99H152N28O24/c1-11-55(5)77-89(145)117-66(38-29-43-108-97(104)105)87(143)127-99(10,40-26-16-14-13-15-25-39-98(9,93(150)121-68(84(140)122-77)45-60-32-21-18-22-33-60)126-86(142)65(37-28-42-107-96(102)103)114-75(135)50-112-80(136)70(51-128)113-58(8)132)94(151)125-76(54(3)4)88(144)123-78(56(6)12-2)90(146)118-67(44-59-30-19-17-20-31-59)83(139)124-79(57(7)131)91(147)120-71(52-129)81(137)111-48-73(133)110-49-74(134)115-72(53-130)85(141)116-64(36-27-41-106-95(100)101)82(138)119-69(92(148)149)46-61-47-109-63-35-24-23-34-62(61)63/h13-14,17-24,30-35,47,54-57,64-72,76-79,109,128-131H,11-12,15-16,25-29,36-46,48-53H2,1-10H3,(H,110,133)(H,111,137)(H,112,136)(H,113,132)(H,114,135)(H,115,134)(H,116,141)(H,117,145)(H,118,146)(H,119,138)(H,120,147)(H,121,150)(H,122,140)(H,123,144)(H,124,139)(H,125,151)(H,126,142)(H,127,143)(H,148,149)(H4,100,101,106)(H4,102,103,107)(H4,104,105,108)/b14-13+/t55-,56-,57+,64-,65-,66-,67-,68-,69-,70-,71-,72-,76-,77-,78-,79-,98-,99-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 275 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-H3/15 from human RXFP3 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50534453
(CHEMBL4557279)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@]1(C)CCC\C=C\CCC[C@](C)(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,t:17| Show InChI InChI=1S/C99H152N28O24/c1-11-55(5)77-89(145)117-66(38-29-43-108-97(104)105)87(143)127-99(10,40-26-16-14-13-15-25-39-98(9,93(150)121-68(84(140)122-77)45-60-32-21-18-22-33-60)126-86(142)65(37-28-42-107-96(102)103)114-75(135)50-112-80(136)70(51-128)113-58(8)132)94(151)125-76(54(3)4)88(144)123-78(56(6)12-2)90(146)118-67(44-59-30-19-17-20-31-59)83(139)124-79(57(7)131)91(147)120-71(52-129)81(137)111-48-73(133)110-49-74(134)115-72(53-130)85(141)116-64(36-27-41-106-95(100)101)82(138)119-69(92(148)149)46-61-47-109-63-35-24-23-34-62(61)63/h13-14,17-24,30-35,47,54-57,64-72,76-79,109,128-131H,11-12,15-16,25-29,36-46,48-53H2,1-10H3,(H,110,133)(H,111,137)(H,112,136)(H,113,132)(H,114,135)(H,115,134)(H,116,141)(H,117,145)(H,118,146)(H,119,138)(H,120,147)(H,121,150)(H,122,140)(H,123,144)(H,124,139)(H,125,151)(H,126,142)(H,127,143)(H,148,149)(H4,100,101,106)(H4,102,103,107)(H4,104,105,108)/b14-13+/t55-,56-,57+,64-,65-,66-,67-,68-,69-,70-,71-,72-,76-,77-,78-,79-,98-,99-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-INSL5 from human RXFP4 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50561921
(CHEMBL4778498)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)N[C@H](CO)Cc1c[nH]c2ccccc12)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 331 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of Eu-labeled H3B1-22R from RXFP3 (unknown origin) stably expressed in CHO-K1 cells by competition binding assay |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00456
BindingDB Entry DOI: 10.7270/Q2G73JFZ |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50534448
(CHEMBL4435599)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@]1(C)CCC\C=C\CCC[C@](C)(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](N)CO)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,t:17| Show InChI InChI=1S/C97H150N28O23/c1-10-54(5)75-87(142)115-65(37-28-42-107-95(103)104)85(140)125-97(9,39-25-15-13-12-14-24-38-96(8,91(147)119-67(82(137)120-75)44-58-31-20-17-21-32-58)124-84(139)64(36-27-41-106-94(101)102)112-73(132)49-110-78(133)61(98)50-126)92(148)123-74(53(3)4)86(141)121-76(55(6)11-2)88(143)116-66(43-57-29-18-16-19-30-57)81(136)122-77(56(7)129)89(144)118-69(51-127)79(134)111-47-71(130)109-48-72(131)113-70(52-128)83(138)114-63(35-26-40-105-93(99)100)80(135)117-68(90(145)146)45-59-46-108-62-34-23-22-33-60(59)62/h12-13,16-23,29-34,46,53-56,61,63-70,74-77,108,126-129H,10-11,14-15,24-28,35-45,47-52,98H2,1-9H3,(H,109,130)(H,110,133)(H,111,134)(H,112,132)(H,113,131)(H,114,138)(H,115,142)(H,116,143)(H,117,135)(H,118,144)(H,119,147)(H,120,137)(H,121,141)(H,122,136)(H,123,148)(H,124,139)(H,125,140)(H,145,146)(H4,99,100,105)(H4,101,102,106)(H4,103,104,107)/b13-12+/t54-,55-,56+,61-,63-,64-,65-,66-,67-,68-,69-,70-,74-,75-,76-,77-,96-,97-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 407 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-INSL5 from human RXFP4 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50534446
(CHEMBL4586048)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@]1(C)CCC\C=C/CCC[C@](C)(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,c:86| Show InChI InChI=1S/C110H173N33O26/c1-11-62(7)86(139-95(159)75(50-64-31-19-17-20-32-64)134-93(157)73(41-42-84(150)151)131-91(155)70(38-28-46-121-106(114)115)128-83(149)56-127-89(153)78(57-144)137-94(158)74(49-60(3)4)133-88(152)68(111)36-27-45-120-105(112)113)100(164)132-72(40-30-48-123-108(118)119)97(161)142-110(10)44-26-16-14-13-15-25-43-109(9,143-98(162)76(51-65-33-21-18-22-34-65)135-101(165)87(63(8)12-2)140-99(163)85(61(5)6)141-104(110)169)103(168)138-79(58-145)90(154)126-54-81(147)125-55-82(148)129-80(59-146)96(160)130-71(39-29-47-122-107(116)117)92(156)136-77(102(166)167)52-66-53-124-69-37-24-23-35-67(66)69/h13-14,17-24,31-35,37,53,60-63,68,70-80,85-87,124,144-146H,11-12,15-16,25-30,36,38-52,54-59,111H2,1-10H3,(H,125,147)(H,126,154)(H,127,153)(H,128,149)(H,129,148)(H,130,160)(H,131,155)(H,132,164)(H,133,152)(H,134,157)(H,135,165)(H,136,156)(H,137,158)(H,138,168)(H,139,159)(H,140,163)(H,141,169)(H,142,161)(H,143,162)(H,150,151)(H,166,167)(H4,112,113,120)(H4,114,115,121)(H4,116,117,122)(H4,118,119,123)/b14-13-/t62-,63-,68-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,85-,86-,87-,109-,110-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 575 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-H3/15 from human RXFP3 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50534444
(CHEMBL4457624)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@]1(C)CCC\C=C/CCC[C@](C)(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,c:89| Show InChI InChI=1S/C112H175N33O27/c1-12-63(7)88(141-97(162)77(51-66-32-20-18-21-33-66)136-95(160)75(42-43-86(153)154)133-93(158)72(39-29-47-122-108(115)116)130-85(152)57-128-90(155)80(58-146)139-96(161)76(50-61(3)4)135-92(157)71(129-65(9)149)38-28-46-121-107(113)114)102(167)134-74(41-31-49-124-110(119)120)99(164)144-112(11)45-27-17-15-14-16-26-44-111(10,145-100(165)78(52-67-34-22-19-23-35-67)137-103(168)89(64(8)13-2)142-101(166)87(62(5)6)143-106(112)172)105(171)140-81(59-147)91(156)127-55-83(150)126-56-84(151)131-82(60-148)98(163)132-73(40-30-48-123-109(117)118)94(159)138-79(104(169)170)53-68-54-125-70-37-25-24-36-69(68)70/h14-15,18-25,32-37,54,61-64,71-82,87-89,125,146-148H,12-13,16-17,26-31,38-53,55-60H2,1-11H3,(H,126,150)(H,127,156)(H,128,155)(H,129,149)(H,130,152)(H,131,151)(H,132,163)(H,133,158)(H,134,167)(H,135,157)(H,136,160)(H,137,168)(H,138,159)(H,139,161)(H,140,171)(H,141,162)(H,142,166)(H,143,172)(H,144,164)(H,145,165)(H,153,154)(H,169,170)(H4,113,114,121)(H4,115,116,122)(H4,117,118,123)(H4,119,120,124)/b15-14-/t63-,64-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,87-,88-,89-,111-,112-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 603 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-H3/15 from human RXFP3 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558037
(CHEMBL4794137)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 912 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50558037
(CHEMBL4794137)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 912 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.5b01786
BindingDB Entry DOI: 10.7270/Q2PC3624 |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50534452
(CHEMBL4474183)Show SMILES CC(C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@](C)(CCC\C=C/CCC[C@](C)(NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(C)=O |r,c:28| Show InChI InChI=1S/C95H142N28O26/c1-51(2)74-87(145)123-95(7,90(149)119-64(41-55-25-14-12-15-26-55)83(141)121-75(53(4)127)86(144)117-68(49-125)78(136)107-45-70(129)106-46-71(130)112-69(50-126)84(142)113-61(32-23-39-103-92(98)99)81(139)116-66(88(146)147)43-57-44-105-59-30-19-18-29-58(57)59)37-21-11-9-8-10-20-36-94(6,89(148)118-62(33-24-40-104-93(100)101)79(137)109-52(3)76(134)120-74)122-85(143)65(42-56-27-16-13-17-28-56)115-82(140)63(34-35-73(132)133)114-80(138)60(31-22-38-102-91(96)97)111-72(131)47-108-77(135)67(48-124)110-54(5)128/h8-9,12-19,25-30,44,51-53,60-69,74-75,105,124-127H,10-11,20-24,31-43,45-50H2,1-7H3,(H,106,129)(H,107,136)(H,108,135)(H,109,137)(H,110,128)(H,111,131)(H,112,130)(H,113,142)(H,114,138)(H,115,140)(H,116,139)(H,117,144)(H,118,148)(H,119,149)(H,120,134)(H,121,141)(H,122,143)(H,123,145)(H,132,133)(H,146,147)(H4,96,97,102)(H4,98,99,103)(H4,100,101,104)/b9-8-/t52-,53+,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,74-,75-,94-,95-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-INSL5 from human RXFP4 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50534451
(CHEMBL4539255)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CS)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCCNC(N)=N)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C136H213N43O33S2/c1-15-71(9)106(127(207)166-86(39-27-51-150-134(142)143)115(195)159-74(12)110(190)175-105(70(7)8)126(206)177-107(72(10)16-2)128(208)170-93(57-78-33-21-18-22-34-78)122(202)178-108(76(14)181)129(209)173-97(67-214)114(194)155-61-99(183)154-62-100(184)162-95(65-180)123(203)163-87(40-28-52-151-135(144)145)118(198)171-94(131(211)212)59-80-60-153-84-37-24-23-35-82(80)84)176-121(201)92(56-77-31-19-17-20-32-77)168-119(199)89(47-48-103(187)188)164-116(196)85(38-26-50-149-133(140)141)161-101(185)63-157-113(193)96(66-213)172-120(200)90(55-68(3)4)167-117(197)88(41-29-53-152-136(146)147)165-125(205)104(69(5)6)174-102(186)64-156-112(192)91(58-79-43-45-81(182)46-44-79)169-124(204)98-42-30-54-179(98)130(210)75(13)160-109(189)73(11)158-111(191)83(137)36-25-49-148-132(138)139/h17-24,31-35,37,43-46,60,68-76,83,85-98,104-108,153,180-182,213-214H,15-16,25-30,36,38-42,47-59,61-67,137H2,1-14H3,(H,154,183)(H,155,194)(H,156,192)(H,157,193)(H,158,191)(H,159,195)(H,160,189)(H,161,185)(H,162,184)(H,163,203)(H,164,196)(H,165,205)(H,166,207)(H,167,197)(H,168,199)(H,169,204)(H,170,208)(H,171,198)(H,172,200)(H,173,209)(H,174,186)(H,175,190)(H,176,201)(H,177,206)(H,178,202)(H,187,188)(H,211,212)(H4,138,139,148)(H4,140,141,149)(H4,142,143,150)(H4,144,145,151)(H4,146,147,152)/t71-,72-,73-,74-,75-,76+,83-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,104-,105-,106-,107-,108-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 1.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-INSL5 from human RXFP4 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50534447
(CHEMBL4582266)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCSSCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C93H142N28O24S2/c1-9-49(5)73-87(141)113-60(30-21-35-102-93(98)99)79(133)112-62(32-37-147-146-36-31-61(81(135)114-63(83(137)119-73)38-53-22-13-11-14-23-53)111-78(132)58(28-19-33-100-91(94)95)108-71(129)44-106-76(130)66(45-122)107-52(8)126)82(136)118-72(48(3)4)86(140)120-74(50(6)10-2)88(142)115-64(39-54-24-15-12-16-25-54)84(138)121-75(51(7)125)89(143)117-67(46-123)77(131)105-42-69(127)104-43-70(128)109-68(47-124)85(139)110-59(29-20-34-101-92(96)97)80(134)116-65(90(144)145)40-55-41-103-57-27-18-17-26-56(55)57/h11-18,22-27,41,48-51,58-68,72-75,103,122-125H,9-10,19-21,28-40,42-47H2,1-8H3,(H,104,127)(H,105,131)(H,106,130)(H,107,126)(H,108,129)(H,109,128)(H,110,139)(H,111,132)(H,112,133)(H,113,141)(H,114,135)(H,115,142)(H,116,134)(H,117,143)(H,118,136)(H,119,137)(H,120,140)(H,121,138)(H,144,145)(H4,94,95,100)(H4,96,97,101)(H4,98,99,102)/t49-,50-,51+,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,72-,73-,74-,75-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-H3/15 from human RXFP3 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 1
(Homo sapiens (Human)) | BDBM50534451
(CHEMBL4539255)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CS)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCCNC(N)=N)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C136H213N43O33S2/c1-15-71(9)106(127(207)166-86(39-27-51-150-134(142)143)115(195)159-74(12)110(190)175-105(70(7)8)126(206)177-107(72(10)16-2)128(208)170-93(57-78-33-21-18-22-34-78)122(202)178-108(76(14)181)129(209)173-97(67-214)114(194)155-61-99(183)154-62-100(184)162-95(65-180)123(203)163-87(40-28-52-151-135(144)145)118(198)171-94(131(211)212)59-80-60-153-84-37-24-23-35-82(80)84)176-121(201)92(56-77-31-19-17-20-32-77)168-119(199)89(47-48-103(187)188)164-116(196)85(38-26-50-149-133(140)141)161-101(185)63-157-113(193)96(66-213)172-120(200)90(55-68(3)4)167-117(197)88(41-29-53-152-136(146)147)165-125(205)104(69(5)6)174-102(186)64-156-112(192)91(58-79-43-45-81(182)46-44-79)169-124(204)98-42-30-54-179(98)130(210)75(13)160-109(189)73(11)158-111(191)83(137)36-25-49-148-132(138)139/h17-24,31-35,37,43-46,60,68-76,83,85-98,104-108,153,180-182,213-214H,15-16,25-30,36,38-42,47-59,61-67,137H2,1-14H3,(H,154,183)(H,155,194)(H,156,192)(H,157,193)(H,158,191)(H,159,195)(H,160,189)(H,161,185)(H,162,184)(H,163,203)(H,164,196)(H,165,205)(H,166,207)(H,167,197)(H,168,199)(H,169,204)(H,170,208)(H,171,198)(H,172,200)(H,173,209)(H,174,186)(H,175,190)(H,176,201)(H,177,206)(H,178,202)(H,187,188)(H,211,212)(H4,138,139,148)(H4,140,141,149)(H4,142,143,150)(H4,144,145,151)(H4,146,147,152)/t71-,72-,73-,74-,75-,76+,83-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,104-,105-,106-,107-,108-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 2.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-H3/15 from human RXFP3 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50534446
(CHEMBL4586048)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@]1(C)CCC\C=C/CCC[C@](C)(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r,c:86| Show InChI InChI=1S/C110H173N33O26/c1-11-62(7)86(139-95(159)75(50-64-31-19-17-20-32-64)134-93(157)73(41-42-84(150)151)131-91(155)70(38-28-46-121-106(114)115)128-83(149)56-127-89(153)78(57-144)137-94(158)74(49-60(3)4)133-88(152)68(111)36-27-45-120-105(112)113)100(164)132-72(40-30-48-123-108(118)119)97(161)142-110(10)44-26-16-14-13-15-25-43-109(9,143-98(162)76(51-65-33-21-18-22-34-65)135-101(165)87(63(8)12-2)140-99(163)85(61(5)6)141-104(110)169)103(168)138-79(58-145)90(154)126-54-81(147)125-55-82(148)129-80(59-146)96(160)130-71(39-29-47-122-107(116)117)92(156)136-77(102(166)167)52-66-53-124-69-37-24-23-35-67(66)69/h13-14,17-24,31-35,37,53,60-63,68,70-80,85-87,124,144-146H,11-12,15-16,25-30,36,38-52,54-59,111H2,1-10H3,(H,125,147)(H,126,154)(H,127,153)(H,128,149)(H,129,148)(H,130,160)(H,131,155)(H,132,164)(H,133,152)(H,134,157)(H,135,165)(H,136,156)(H,137,158)(H,138,168)(H,139,159)(H,140,163)(H,141,169)(H,142,161)(H,143,162)(H,150,151)(H,166,167)(H4,112,113,120)(H4,114,115,121)(H4,116,117,122)(H4,118,119,123)/b14-13-/t62-,63-,68-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,85-,86-,87-,109-,110-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-INSL5 from human RXFP4 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50534450
(CHEMBL4573196)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C96H149N29O26/c1-9-51(5)76(123-86(143)65(40-55-24-13-11-14-25-55)118-84(141)64(34-35-74(134)135)116-81(138)60(31-21-37-104-94(98)99)112-73(133)46-110-79(136)68(47-126)111-54(8)130)90(147)117-63(33-23-39-106-96(102)103)82(139)114-61(30-19-20-36-97)85(142)122-75(50(3)4)89(146)124-77(52(6)10-2)91(148)119-66(41-56-26-15-12-16-27-56)87(144)125-78(53(7)129)92(149)121-69(48-127)80(137)109-44-71(131)108-45-72(132)113-70(49-128)88(145)115-62(32-22-38-105-95(100)101)83(140)120-67(93(150)151)42-57-43-107-59-29-18-17-28-58(57)59/h11-18,24-29,43,50-53,60-70,75-78,107,126-129H,9-10,19-23,30-42,44-49,97H2,1-8H3,(H,108,131)(H,109,137)(H,110,136)(H,111,130)(H,112,133)(H,113,132)(H,114,139)(H,115,145)(H,116,138)(H,117,147)(H,118,141)(H,119,148)(H,120,140)(H,121,149)(H,122,142)(H,123,143)(H,124,146)(H,125,144)(H,134,135)(H,150,151)(H4,98,99,104)(H4,100,101,105)(H4,102,103,106)/t51-,52-,53+,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,75-,76-,77-,78-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-INSL5 from human RXFP4 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50534447
(CHEMBL4582266)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCSSCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C93H142N28O24S2/c1-9-49(5)73-87(141)113-60(30-21-35-102-93(98)99)79(133)112-62(32-37-147-146-36-31-61(81(135)114-63(83(137)119-73)38-53-22-13-11-14-23-53)111-78(132)58(28-19-33-100-91(94)95)108-71(129)44-106-76(130)66(45-122)107-52(8)126)82(136)118-72(48(3)4)86(140)120-74(50(6)10-2)88(142)115-64(39-54-24-15-12-16-25-54)84(138)121-75(51(7)125)89(143)117-67(46-123)77(131)105-42-69(127)104-43-70(128)109-68(47-124)85(139)110-59(29-20-34-101-92(96)97)80(134)116-65(90(144)145)40-55-41-103-57-27-18-17-26-56(55)57/h11-18,22-27,41,48-51,58-68,72-75,103,122-125H,9-10,19-21,28-40,42-47H2,1-8H3,(H,104,127)(H,105,131)(H,106,130)(H,107,126)(H,108,129)(H,109,128)(H,110,139)(H,111,132)(H,112,133)(H,113,141)(H,114,135)(H,115,142)(H,116,134)(H,117,143)(H,118,136)(H,119,137)(H,120,140)(H,121,138)(H,144,145)(H4,94,95,100)(H4,96,97,101)(H4,98,99,102)/t49-,50-,51+,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,72-,73-,74-,75-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-INSL5 from human RXFP4 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50534449
(CHEMBL4462750)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C96H147N29O25/c1-9-51(5)76-90(146)117-63(33-23-39-106-96(101)102)82(138)114-61(30-19-20-36-103-71(131)35-34-64(84(140)118-65(86(142)123-76)40-55-24-13-11-14-25-55)116-81(137)60(31-21-37-104-94(97)98)112-74(134)46-110-79(135)68(47-126)111-54(8)130)85(141)122-75(50(3)4)89(145)124-77(52(6)10-2)91(147)119-66(41-56-26-15-12-16-27-56)87(143)125-78(53(7)129)92(148)121-69(48-127)80(136)109-44-72(132)108-45-73(133)113-70(49-128)88(144)115-62(32-22-38-105-95(99)100)83(139)120-67(93(149)150)42-57-43-107-59-29-18-17-28-58(57)59/h11-18,24-29,43,50-53,60-70,75-78,107,126-129H,9-10,19-23,30-42,44-49H2,1-8H3,(H,103,131)(H,108,132)(H,109,136)(H,110,135)(H,111,130)(H,112,134)(H,113,133)(H,114,138)(H,115,144)(H,116,137)(H,117,146)(H,118,140)(H,119,147)(H,120,139)(H,121,148)(H,122,141)(H,123,142)(H,124,145)(H,125,143)(H,149,150)(H4,97,98,104)(H4,99,100,105)(H4,101,102,106)/t51-,52-,53+,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,75-,76-,77-,78-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-INSL5 from human RXFP4 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
Relaxin-3 receptor 2
(Homo sapiens (Human)) | BDBM50534441
(CHEMBL4555053)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C93H142N28O26/c1-10-48(5)73(119-83(139)62(37-53-23-14-12-15-24-53)114-82(138)61(32-33-71(130)131)112-80(136)58(29-20-34-100-91(94)95)109-70(129)43-106-77(133)65(44-122)108-52(9)126)87(143)113-59(30-21-35-101-92(96)97)79(135)107-50(7)76(132)118-72(47(3)4)86(142)120-74(49(6)11-2)88(144)115-63(38-54-25-16-13-17-26-54)84(140)121-75(51(8)125)89(145)117-66(45-123)78(134)105-41-68(127)104-42-69(128)110-67(46-124)85(141)111-60(31-22-36-102-93(98)99)81(137)116-64(90(146)147)39-55-40-103-57-28-19-18-27-56(55)57/h12-19,23-28,40,47-51,58-67,72-75,103,122-125H,10-11,20-22,29-39,41-46H2,1-9H3,(H,104,127)(H,105,134)(H,106,133)(H,107,135)(H,108,126)(H,109,129)(H,110,128)(H,111,141)(H,112,136)(H,113,143)(H,114,138)(H,115,144)(H,116,137)(H,117,145)(H,118,132)(H,119,139)(H,120,142)(H,121,140)(H,130,131)(H,146,147)(H4,94,95,100)(H4,96,97,101)(H4,98,99,102)/t48-,49-,50-,51+,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,72-,73-,74-,75-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Displacement of Eu-INSL5 from human RXFP4 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay |
J Med Chem 59: 7445-56 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00265
BindingDB Entry DOI: 10.7270/Q2CZ3BNG |
More data for this
Ligand-Target Pair | |
1-phosphatidylinositol 3-phosphate 5-kinase
(Homo sapiens) | BDBM50590927
(APILIMOD | Apilimod | STA 5326 | STA-5326 | Sta-53...)Show SMILES Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.309 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00697
BindingDB Entry DOI: 10.7270/Q2MP5771 |
More data for this
Ligand-Target Pair | |
1-phosphatidylinositol 3-phosphate 5-kinase
(Homo sapiens) | BDBM50590927
(APILIMOD | Apilimod | STA 5326 | STA-5326 | Sta-53...)Show SMILES Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.312 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00697
BindingDB Entry DOI: 10.7270/Q2MP5771 |
More data for this
Ligand-Target Pair | |
1-phosphatidylinositol 3-phosphate 5-kinase
(Homo sapiens) | BDBM50590928
(CHEMBL2178735)Show SMILES Nc1ccc(cn1)C(=O)Nc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.820 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00697
BindingDB Entry DOI: 10.7270/Q2MP5771 |
More data for this
Ligand-Target Pair | |
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