BindingDB PrimarySearch

Found 23 hits with Last Name = 'santi' and Initial = 'md'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50240899 (5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3-methoxy-chrom...) Show SMILES COc1c(oc2cc(O)cc(O)c2c1=O)-c1ccc(O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...				Eur J Med Chem 143: 577-582 (2018) Article DOI: 10.1016/j.ejmech.2017.11.071 BindingDB Entry DOI: 10.7270/Q2X35144
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM26663 ((2S)-5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2-phe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112718 BindingDB Entry DOI: 10.7270/Q2SB49GQ
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50292535 (5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3,6-dimethoxy-c...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...				Eur J Med Chem 143: 577-582 (2018) Article DOI: 10.1016/j.ejmech.2017.11.071 BindingDB Entry DOI: 10.7270/Q2X35144
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50004000 ((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112718 BindingDB Entry DOI: 10.7270/Q2SB49GQ
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50464571 (CHEBI:70009 \| CHEMBL1689269 \| Myricetin 3,3'',4''-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...				Eur J Med Chem 143: 577-582 (2018) Article DOI: 10.1016/j.ejmech.2017.11.071 BindingDB Entry DOI: 10.7270/Q2X35144
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50240898 (5,7-Dihydroxy-3,6-dimethoxy-2-(4-methoxy-phenyl)-c...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...				Eur J Med Chem 143: 577-582 (2018) Article DOI: 10.1016/j.ejmech.2017.11.071 BindingDB Entry DOI: 10.7270/Q2X35144
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50140241 (Allopurinol \| Aloral \| Aluline 100 \| Aluline 300 \|...) Show SMILES O=c1[nH]cnc2[nH]ncc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...				Eur J Med Chem 143: 577-582 (2018) Article DOI: 10.1016/j.ejmech.2017.11.071 BindingDB Entry DOI: 10.7270/Q2X35144
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50237231 (CHEMBL4063130) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs				Bioorg Med Chem Lett 27: 1789-1794 (2017) Article DOI: 10.1016/j.bmcl.2017.02.058 BindingDB Entry DOI: 10.7270/Q2MW2KDB
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50237232 (CHEMBL516671) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs				Bioorg Med Chem Lett 27: 1789-1794 (2017) Article DOI: 10.1016/j.bmcl.2017.02.058 BindingDB Entry DOI: 10.7270/Q2MW2KDB
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50464570 (CHEMBL3407503) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...				Eur J Med Chem 143: 577-582 (2018) Article DOI: 10.1016/j.ejmech.2017.11.071 BindingDB Entry DOI: 10.7270/Q2X35144
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50237229 (CHEMBL4083227) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs				Bioorg Med Chem Lett 27: 1789-1794 (2017) Article DOI: 10.1016/j.bmcl.2017.02.058 BindingDB Entry DOI: 10.7270/Q2MW2KDB
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50237230 (CHEMBL4101226) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs				Bioorg Med Chem Lett 27: 1789-1794 (2017) Article DOI: 10.1016/j.bmcl.2017.02.058 BindingDB Entry DOI: 10.7270/Q2MW2KDB
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50464572 (CHEMBL3407749) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...				Eur J Med Chem 143: 577-582 (2018) Article DOI: 10.1016/j.ejmech.2017.11.071 BindingDB Entry DOI: 10.7270/Q2X35144
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50464569 (7-Trimethylkaempferol \| CHEMBL77686) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...				Eur J Med Chem 143: 577-582 (2018) Article DOI: 10.1016/j.ejmech.2017.11.071 BindingDB Entry DOI: 10.7270/Q2X35144
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50464573 (CHEMBL521934) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...				Eur J Med Chem 143: 577-582 (2018) Article DOI: 10.1016/j.ejmech.2017.11.071 BindingDB Entry DOI: 10.7270/Q2X35144
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50464574 (CHEMBL4294702) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...				Eur J Med Chem 143: 577-582 (2018) Article DOI: 10.1016/j.ejmech.2017.11.071 BindingDB Entry DOI: 10.7270/Q2X35144
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50521808 (CHEMBL4462424) Show SMILES COc1cc(O)c(C(=O)\C=C\c2ccccc2)c(O)c1C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16F0 cells assessed as reduction in melanin production incubated for 24 hrs by spectrophotometric analysis				Bioorg Med Chem 27: 3722-3728 (2019) Article DOI: 10.1016/j.bmc.2019.06.041 BindingDB Entry DOI: 10.7270/Q2D22212
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50565698 (CHEMBL3085398) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112718 BindingDB Entry DOI: 10.7270/Q2SB49GQ
TBA					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50521808 (CHEMBL4462424) Show SMILES COc1cc(O)c(C(=O)\C=C\c2ccccc2)c(O)c1C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16F0 cells using L-DOPA as substrate by UV-Visible spectrophotometric analysis				Bioorg Med Chem 27: 3722-3728 (2019) Article DOI: 10.1016/j.bmc.2019.06.041 BindingDB Entry DOI: 10.7270/Q2D22212
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50521808 (CHEMBL4462424) Show SMILES COc1cc(O)c(C(=O)\C=C\c2ccccc2)c(O)c1C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity using L-dopa as substrate preincubated for 10 mins followed by substrate addition by UV-Visibl...				Bioorg Med Chem 27: 3722-3728 (2019) Article DOI: 10.1016/j.bmc.2019.06.041 BindingDB Entry DOI: 10.7270/Q2D22212
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16F0 cells using L-DOPA as substrate by UV-Visible spectrophotometric analysis				Bioorg Med Chem 27: 3722-3728 (2019) Article DOI: 10.1016/j.bmc.2019.06.041 BindingDB Entry DOI: 10.7270/Q2D22212
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity using L-dopa as substrate preincubated for 10 mins followed by substrate addition by UV-Visibl...				Bioorg Med Chem 27: 3722-3728 (2019) Article DOI: 10.1016/j.bmc.2019.06.041 BindingDB Entry DOI: 10.7270/Q2D22212
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs				Bioorg Med Chem Lett 27: 1789-1794 (2017) Article DOI: 10.1016/j.bmcl.2017.02.058 BindingDB Entry DOI: 10.7270/Q2MW2KDB
Universidad Nacional de C£rdoba Curated by ChEMBL					More data for this Ligand-Target Pair