Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50376383 (CHEMBL259972) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay | Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50084631 (CHEMBL3427203) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL | Assay Description Inhibition of LPS-induced COX1 in human whole blood assessed as reduction in TXB2 levels by radioimmunoassay | Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM13065 (5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay | Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50376383 (CHEMBL259972) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 164: 59-76 (2019) Article DOI: 10.1016/j.ejmech.2018.12.029 BindingDB Entry DOI: 10.7270/Q2W099CR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50376383 (CHEMBL259972) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Thomas Jefferson University Curated by ChEMBL | Assay Description Inhibition of ovine COX1 catalytic activity using arachidonic acid as substrate preincubated for 5 mins followed by substrate and hemin addition meas... | Eur J Med Chem 138: 661-668 (2017) Article DOI: 10.1016/j.ejmech.2017.06.045 BindingDB Entry DOI: 10.7270/Q2D2215F | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50376383 (CHEMBL259972) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of human COX1 assessed as reduction in appearance of oxidized TMPD using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 141: 404-416 (2017) Article DOI: 10.1016/j.ejmech.2017.09.066 BindingDB Entry DOI: 10.7270/Q2NS0XFF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50556691 (CHEMBL4760140) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric method | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112919 BindingDB Entry DOI: 10.7270/Q2CF9TRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50376383 (CHEMBL259972) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric method | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112919 BindingDB Entry DOI: 10.7270/Q2CF9TRQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50531488 (CHEMBL4590829) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 164: 59-76 (2019) Article DOI: 10.1016/j.ejmech.2018.12.029 BindingDB Entry DOI: 10.7270/Q2W099CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50153038 (5-Ethyl-3,4-diphenyl-isoxazole | CHEMBL361504) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "A. Moro" Curated by ChEMBL | Assay Description Inhibition of human platelet COX1 by whole blood assay | Eur J Med Chem 74: 606-18 (2014) Article DOI: 10.1016/j.ejmech.2013.12.023 BindingDB Entry DOI: 10.7270/Q2SF305M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50556695 (CHEMBL4746714) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric method | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112919 BindingDB Entry DOI: 10.7270/Q2CF9TRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50531485 (CHEMBL4515876) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of human COX2 using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 164: 59-76 (2019) Article DOI: 10.1016/j.ejmech.2018.12.029 BindingDB Entry DOI: 10.7270/Q2W099CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50556696 (CHEMBL4759732) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric method | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112919 BindingDB Entry DOI: 10.7270/Q2CF9TRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50531483 (CHEMBL4462870) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 164: 59-76 (2019) Article DOI: 10.1016/j.ejmech.2018.12.029 BindingDB Entry DOI: 10.7270/Q2W099CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM13065 (5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "A. Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX1 by peroxidase activity-based colorimetric assay | Eur J Med Chem 74: 606-18 (2014) Article DOI: 10.1016/j.ejmech.2013.12.023 BindingDB Entry DOI: 10.7270/Q2SF305M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50556690 (CHEMBL4799478) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric method | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112919 BindingDB Entry DOI: 10.7270/Q2CF9TRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50153036 (5-Methyl-3,4-diphenyl-isoxazole | CHEMBL365033) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "A. Moro" Curated by ChEMBL | Assay Description Inhibition of human platelet COX1 by whole blood assay | Eur J Med Chem 74: 606-18 (2014) Article DOI: 10.1016/j.ejmech.2013.12.023 BindingDB Entry DOI: 10.7270/Q2SF305M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50556697 (CHEMBL4789403) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human COX-2 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric method | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112919 BindingDB Entry DOI: 10.7270/Q2CF9TRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "A. Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX1 by peroxidase activity-based colorimetric assay | Eur J Med Chem 74: 606-18 (2014) Article DOI: 10.1016/j.ejmech.2013.12.023 BindingDB Entry DOI: 10.7270/Q2SF305M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50531486 (CHEMBL4475349) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 164: 59-76 (2019) Article DOI: 10.1016/j.ejmech.2018.12.029 BindingDB Entry DOI: 10.7270/Q2W099CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50531487 (CHEMBL4571499) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 164: 59-76 (2019) Article DOI: 10.1016/j.ejmech.2018.12.029 BindingDB Entry DOI: 10.7270/Q2W099CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50556685 (CHEMBL4740788) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human COX-2 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric method | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112919 BindingDB Entry DOI: 10.7270/Q2CF9TRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50556688 (CHEMBL4744394) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric method | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112919 BindingDB Entry DOI: 10.7270/Q2CF9TRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50531486 (CHEMBL4475349) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of human COX2 using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 164: 59-76 (2019) Article DOI: 10.1016/j.ejmech.2018.12.029 BindingDB Entry DOI: 10.7270/Q2W099CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50531487 (CHEMBL4571499) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of human COX2 using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 164: 59-76 (2019) Article DOI: 10.1016/j.ejmech.2018.12.029 BindingDB Entry DOI: 10.7270/Q2W099CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50283373 (CHEMBL4171339) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of human COX2 assessed as reduction in appearance of oxidized TMPD using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 141: 404-416 (2017) Article DOI: 10.1016/j.ejmech.2017.09.066 BindingDB Entry DOI: 10.7270/Q2NS0XFF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50283371 (CHEMBL4163044) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of human COX1 assessed as reduction in appearance of oxidized TMPD using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 141: 404-416 (2017) Article DOI: 10.1016/j.ejmech.2017.09.066 BindingDB Entry DOI: 10.7270/Q2NS0XFF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50491544 (CHEMBL2380862) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassay | J Med Chem 56: 4277-99 (2013) Article DOI: 10.1021/jm301905a BindingDB Entry DOI: 10.7270/Q21V5HVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50491534 (CHEMBL2380863) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassay | J Med Chem 56: 4277-99 (2013) Article DOI: 10.1021/jm301905a BindingDB Entry DOI: 10.7270/Q21V5HVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Ovis aries (Sheep)) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "A. Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX2 by peroxidase activity-based colorimetric assay | Eur J Med Chem 74: 606-18 (2014) Article DOI: 10.1016/j.ejmech.2013.12.023 BindingDB Entry DOI: 10.7270/Q2SF305M | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50009859 ((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Inhibition of COX-1 in human washed platelet assessed as inhibition of 0.5 uM arachidonic acid-induced TXB2 formation incubated for 25 mins prior to ... | J Med Chem 56: 4277-99 (2013) Article DOI: 10.1021/jm301905a BindingDB Entry DOI: 10.7270/Q21V5HVV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50531496 (CHEMBL4441970) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of human COX2 using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 164: 59-76 (2019) Article DOI: 10.1016/j.ejmech.2018.12.029 BindingDB Entry DOI: 10.7270/Q2W099CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50556696 (CHEMBL4759732) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human COX-2 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric method | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112919 BindingDB Entry DOI: 10.7270/Q2CF9TRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50491536 (CHEMBL2380867) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassay | J Med Chem 56: 4277-99 (2013) Article DOI: 10.1021/jm301905a BindingDB Entry DOI: 10.7270/Q21V5HVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50491529 (CHEMBL2380876) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassay | J Med Chem 56: 4277-99 (2013) Article DOI: 10.1021/jm301905a BindingDB Entry DOI: 10.7270/Q21V5HVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50531496 (CHEMBL4441970) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 164: 59-76 (2019) Article DOI: 10.1016/j.ejmech.2018.12.029 BindingDB Entry DOI: 10.7270/Q2W099CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50531483 (CHEMBL4462870) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of human COX2 using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 164: 59-76 (2019) Article DOI: 10.1016/j.ejmech.2018.12.029 BindingDB Entry DOI: 10.7270/Q2W099CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50283373 (CHEMBL4171339) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "Aldo Moro" Curated by ChEMBL | Assay Description Inhibition of human COX1 assessed as reduction in appearance of oxidized TMPD using arachidonic acid as substrate by colorimetric assay | Eur J Med Chem 141: 404-416 (2017) Article DOI: 10.1016/j.ejmech.2017.09.066 BindingDB Entry DOI: 10.7270/Q2NS0XFF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Ovis aries (Sheep)) | BDBM50376383 (CHEMBL259972) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX-2 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay | Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50153040 (3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL | Assay Description Inhibition of LPS-induced COX1 in human whole blood assessed as reduction in TXB2 levels by radioimmunoassay | Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50153040 (3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "A. Moro" Curated by ChEMBL | Assay Description Inhibition of human platelet COX1 by whole blood assay | Eur J Med Chem 74: 606-18 (2014) Article DOI: 10.1016/j.ejmech.2013.12.023 BindingDB Entry DOI: 10.7270/Q2SF305M | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50556694 (CHEMBL4758894) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human COX-2 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric method | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112919 BindingDB Entry DOI: 10.7270/Q2CF9TRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50153040 (3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassay | J Med Chem 56: 4277-99 (2013) Article DOI: 10.1021/jm301905a BindingDB Entry DOI: 10.7270/Q21V5HVV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50084649 (CHEMBL3114664) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "A. Moro" Curated by ChEMBL | Assay Description Inhibition of COX1 in human OVCAR3 cells using [14C]arachidonic acid as substrate preincubated for 30 mins before substrate addition by radioactivity... | Eur J Med Chem 74: 606-18 (2014) Article DOI: 10.1016/j.ejmech.2013.12.023 BindingDB Entry DOI: 10.7270/Q2SF305M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50556693 (CHEMBL4794474) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human COX-2 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric method | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112919 BindingDB Entry DOI: 10.7270/Q2CF9TRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50491533 (CHEMBL2380864) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 810 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassay | J Med Chem 56: 4277-99 (2013) Article DOI: 10.1021/jm301905a BindingDB Entry DOI: 10.7270/Q21V5HVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50556692 (CHEMBL4789452) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric method | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112919 BindingDB Entry DOI: 10.7270/Q2CF9TRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50084649 (CHEMBL3114664) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bari "A. Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX1 by peroxidase activity-based colorimetric assay | Eur J Med Chem 74: 606-18 (2014) Article DOI: 10.1016/j.ejmech.2013.12.023 BindingDB Entry DOI: 10.7270/Q2SF305M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50491534 (CHEMBL2380863) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari A. Moro Curated by ChEMBL | Assay Description Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassay | J Med Chem 56: 4277-99 (2013) Article DOI: 10.1021/jm301905a BindingDB Entry DOI: 10.7270/Q21V5HVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50084649 (CHEMBL3114664) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari"A.Moro" Curated by ChEMBL | Assay Description Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assay | Eur J Med Chem 94: 252-64 (2015) Article DOI: 10.1016/j.ejmech.2015.02.049 BindingDB Entry DOI: 10.7270/Q2416ZRX | |||||||||||
More data for this Ligand-Target Pair |
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