Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182![]() ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Displacement of fluormone VDR red from human full-length VDR after 4 hrs by fluorescence polarization assay | Eur J Med Chem 157: 1174-1191 (2018) Article DOI: 10.1016/j.ejmech.2018.08.085 BindingDB Entry DOI: 10.7270/Q2WH2SQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50469127![]() (CHEMBL4288947) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Displacement of fluormone VDR red from human full-length VDR after 4 hrs by fluorescence polarization assay | Eur J Med Chem 157: 1174-1191 (2018) Article DOI: 10.1016/j.ejmech.2018.08.085 BindingDB Entry DOI: 10.7270/Q2WH2SQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50441900![]() (CHEMBL2434990) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 115 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Displacement of fluormone VDR red from human full-length VDR after 4 hrs by fluorescence polarization assay | Eur J Med Chem 157: 1174-1191 (2018) Article DOI: 10.1016/j.ejmech.2018.08.085 BindingDB Entry DOI: 10.7270/Q2WH2SQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50469128![]() (CHEMBL4290851) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Displacement of fluormone VDR red from human full-length VDR after 4 hrs by fluorescence polarization assay | Eur J Med Chem 157: 1174-1191 (2018) Article DOI: 10.1016/j.ejmech.2018.08.085 BindingDB Entry DOI: 10.7270/Q2WH2SQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50469128![]() (CHEMBL4290851) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Binding affinity to VDR in scrambled siRNA-transfected human MCF7 cells assessed as cell growth inhibition by measuring reduction in BrdU incorporati... | Eur J Med Chem 157: 1174-1191 (2018) Article DOI: 10.1016/j.ejmech.2018.08.085 BindingDB Entry DOI: 10.7270/Q2WH2SQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50469127![]() (CHEMBL4288947) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Binding affinity to VDR in scrambled siRNA-transfected human MCF7 cells assessed as cell growth inhibition by measuring reduction in BrdU incorporati... | Eur J Med Chem 157: 1174-1191 (2018) Article DOI: 10.1016/j.ejmech.2018.08.085 BindingDB Entry DOI: 10.7270/Q2WH2SQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50441900![]() (CHEMBL2434990) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Binding affinity to VDR in scrambled siRNA-transfected human MCF7 cells assessed as cell growth inhibition by measuring reduction in BrdU incorporati... | Eur J Med Chem 157: 1174-1191 (2018) Article DOI: 10.1016/j.ejmech.2018.08.085 BindingDB Entry DOI: 10.7270/Q2WH2SQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182![]() ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 6.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Binding affinity to VDR in scrambled siRNA-transfected human MCF7 cells assessed as cell growth inhibition by measuring reduction in BrdU incorporati... | Eur J Med Chem 157: 1174-1191 (2018) Article DOI: 10.1016/j.ejmech.2018.08.085 BindingDB Entry DOI: 10.7270/Q2WH2SQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha/Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50441900![]() (CHEMBL2434990) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Transactivation of recombinant human VDR/RXRalpha expressed in HEK293 cells after 24 hrs by Dual-luciferase reporter gene assay | Eur J Med Chem 157: 1174-1191 (2018) Article DOI: 10.1016/j.ejmech.2018.08.085 BindingDB Entry DOI: 10.7270/Q2WH2SQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha/Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182![]() ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Transactivation of recombinant human VDR/RXRalpha expressed in HEK293 cells after 24 hrs by Dual-luciferase reporter gene assay | Eur J Med Chem 157: 1174-1191 (2018) Article DOI: 10.1016/j.ejmech.2018.08.085 BindingDB Entry DOI: 10.7270/Q2WH2SQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha/Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50469127![]() (CHEMBL4288947) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Transactivation of recombinant human VDR/RXRalpha expressed in HEK293 cells after 24 hrs by Dual-luciferase reporter gene assay | Eur J Med Chem 157: 1174-1191 (2018) Article DOI: 10.1016/j.ejmech.2018.08.085 BindingDB Entry DOI: 10.7270/Q2WH2SQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha/Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50469128![]() (CHEMBL4290851) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Transactivation of recombinant human VDR/RXRalpha expressed in HEK293 cells after 24 hrs by Dual-luciferase reporter gene assay | Eur J Med Chem 157: 1174-1191 (2018) Article DOI: 10.1016/j.ejmech.2018.08.085 BindingDB Entry DOI: 10.7270/Q2WH2SQJ | |||||||||||
More data for this Ligand-Target Pair |