Compile Data Set for Download or QSAR

Found 91 hits with Last Name = 'lavergne' and Initial = 'o'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410700 (US10377772, Compound N1) Show SMILES C1C[C@H]2COc3cccc(c3)-c3cnn4ccc(NCCN2C1)nc34 |r| Show InChI InChI=1S/C19H21N5O/c1-3-14-11-16(5-1)25-13-15-4-2-8-23(15)10-7-20-18-6-9-24-19(22-18)17(14)12-21-24/h1,3,5-6,9,11-12,15H,2,4,7-8,10,13H2,(H,20,22)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410701 (US10377772, Compound N2) Show SMILES Fc1ccc2NC[C@@H]3CCCN3CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C19H21FN6/c20-17-4-3-13-10-15(17)16-12-23-26-8-5-18(24-19(16)26)21-6-9-25-7-1-2-14(25)11-22-13/h3-5,8,10,12,14,22H,1-2,6-7,9,11H2,(H,21,24)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410702 (US10377772, Compound N3) Show SMILES Fc1ccc2NCCN3CCC(CC3)Nc3ccn4ncc(-c1c2)c4n3 |(4.89,1.33,;3.8,.24,;4.2,-1.25,;3.11,-2.34,;1.62,-1.94,;.53,-3.03,;-1.35,-4.91,;-3.55,-4.33,;-3.55,-2.79,;-4.89,-2.02,;-4.89,-.48,;-3.55,.29,;-2.22,-.48,;-2.22,-2.02,;-3.55,1.83,;-2.22,2.6,;-2.22,4.14,;-.89,4.91,;.45,4.14,;1.91,4.61,;2.82,3.37,;1.91,2.12,;2.31,.64,;1.22,-.45,;.45,2.6,;-.89,1.83,)| Show InChI InChI=1S/C19H21FN6/c20-17-2-1-14-11-15(17)16-12-22-26-9-5-18(24-19(16)26)23-13-3-7-25(8-4-13)10-6-21-14/h1-2,5,9,11-13,21H,3-4,6-8,10H2,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410703 (US10377772, Compound N4) Show SMILES Fc1ccc2NC3CCN(CC3)CCNc3ccn4ncc(-c1c2)c4n3 |(4.62,1.74,;3.85,.41,;4.62,-.93,;3.85,-2.26,;2.31,-2.26,;1.44,-3.76,;-.86,-3.76,;-2.2,-4.53,;-3.53,-3.76,;-3.53,-2.22,;-2.2,-1.45,;-.86,-2.22,;-4.62,-1.13,;-3.53,-.04,;-3.93,1.45,;-2.59,2.22,;-2.59,3.76,;-1.26,4.53,;.07,3.76,;1.54,4.23,;2.44,2.99,;1.54,1.74,;2.31,.41,;1.54,-.93,;.07,2.22,;-1.26,1.45,)| Show InChI InChI=1S/C19H21FN6/c20-17-2-1-14-11-15(17)16-12-22-26-9-5-18(24-19(16)26)21-6-10-25-7-3-13(23-14)4-8-25/h1-2,5,9,11-13,23H,3-4,6-8,10H2,(H,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410704 (US10377772, Compound N5) Show SMILES Fc1ccc2NCCN3CCCC3CCNc3ccn4ncc(-c1c2)c4n3 Show InChI InChI=1S/C20H23FN6/c21-18-4-3-14-12-16(18)17-13-24-27-10-6-19(25-20(17)27)23-7-5-15-2-1-9-26(15)11-8-22-14/h3-4,6,10,12-13,15,22H,1-2,5,7-9,11H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410705 (US10377772, Compound N6) Show SMILES Fc1ccc2NCCCN3CCC(C3)Nc3ccn4ncc(-c1c2)c4n3 Show InChI InChI=1S/C19H21FN6/c20-17-3-2-13-10-15(17)16-11-22-26-9-5-18(24-19(16)26)23-14-4-8-25(12-14)7-1-6-21-13/h2-3,5,9-11,14,21H,1,4,6-8,12H2,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410706 (US10377772, Compound N7) Show SMILES Fc1ccc2NC3CCN(CC3)CCOc3ccn4ncc(-c1c2)c4n3 |(4.89,1.01,;3.8,-.08,;4.2,-1.57,;3.11,-2.65,;1.62,-2.26,;.53,-3.35,;-1.82,-3.82,;-3.15,-4.59,;-4.49,-3.82,;-4.49,-2.28,;-3.15,-1.51,;-1.82,-2.28,;-4.89,-.8,;-3.55,-.03,;-3.55,1.51,;-2.22,2.28,;-2.22,3.82,;-.89,4.59,;.45,3.82,;1.91,4.3,;2.82,3.05,;1.91,1.81,;2.31,.32,;1.22,-.77,;.45,2.28,;-.89,1.51,)| Show InChI InChI=1S/C19H20FN5O/c20-17-2-1-14-11-15(17)16-12-21-25-8-5-18(23-19(16)25)26-10-9-24-6-3-13(22-14)4-7-24/h1-2,5,8,11-13,22H,3-4,6-7,9-10H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410707 (US10377772, Compound N8) Show SMILES Fc1ccc2OC[C@@H]3CCCN3CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C19H20FN5O/c20-17-4-3-14-10-15(17)16-11-22-25-8-5-18(23-19(16)25)21-6-9-24-7-1-2-13(24)12-26-14/h3-5,8,10-11,13H,1-2,6-7,9,12H2,(H,21,23)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410709 (US10377772, Compound N10) Show SMILES Cc1cc(F)c-2cc1NC[C@@H]1CCCN1CCNc1ccn3ncc-2c3n1 |r| Show InChI InChI=1S/C20H23FN6/c1-13-9-17(21)15-10-18(13)23-11-14-3-2-6-26(14)8-5-22-19-4-7-27-20(25-19)16(15)12-24-27/h4,7,9-10,12,14,23H,2-3,5-6,8,11H2,1H3,(H,22,25)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410710 (US10377772, Compound N11) Show SMILES CN1CCN2CCC[C@H]2COc2ccc(F)c(c2)-c2cnn3ccc1nc23 |r| Show InChI InChI=1S/C20H22FN5O/c1-24-9-10-25-7-2-3-14(25)13-27-15-4-5-18(21)16(11-15)17-12-22-26-8-6-19(24)23-20(17)26/h4-6,8,11-12,14H,2-3,7,9-10,13H2,1H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410711 (US10377772, Compound N12) Show SMILES F[C@@H]1C[C@H]2COc3ccc(F)c(c3)-c3cnn4ccc(NCCN2C1)nc34 |r| Show InChI InChI=1S/C19H19F2N5O/c20-12-7-13-11-27-14-1-2-17(21)15(8-14)16-9-23-26-5-3-18(24-19(16)26)22-4-6-25(13)10-12/h1-3,5,8-9,12-13H,4,6-7,10-11H2,(H,22,24)/t12-,13+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410713 (US10377772, Compound N14) Show SMILES Fc1ccc2OC[C@@H]3CCCN3CCCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C20H22FN5O/c21-18-5-4-15-11-16(18)17-12-23-26-10-6-19(24-20(17)26)22-7-2-9-25-8-1-3-14(25)13-27-15/h4-6,10-12,14H,1-3,7-9,13H2,(H,22,24)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410714 (US10377772, Compound N15) Show SMILES CN1C2CCN(CC2)CCOc2ccc(F)c(c2)-c2cnn3ccc1nc23 Show InChI InChI=1S/C20H22FN5O/c1-24-14-4-7-25(8-5-14)10-11-27-15-2-3-18(21)16(12-15)17-13-22-26-9-6-19(24)23-20(17)26/h2-3,6,9,12-14H,4-5,7-8,10-11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410715 (US10377772, Compound N16) Show SMILES CN1CCN2CCC[C@H]2CNc2ccc(F)c(c2)-c2cnn3ccc1nc23 |r| Show InChI InChI=1S/C20H23FN6/c1-25-9-10-26-7-2-3-15(26)12-22-14-4-5-18(21)16(11-14)17-13-23-27-8-6-19(25)24-20(17)27/h4-6,8,11,13,15,22H,2-3,7,9-10,12H2,1H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410716 (US10377772, Compound N17) Show SMILES Fc1ccc2OC[C@@H]3CCCCN3CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C20H22FN5O/c21-18-5-4-15-11-16(18)17-12-23-26-9-6-19(24-20(17)26)22-7-10-25-8-2-1-3-14(25)13-27-15/h4-6,9,11-12,14H,1-3,7-8,10,13H2,(H,22,24)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410717 (US10377772, Compound N18) Show SMILES Fc1ccc2O[C@@H]3CCCCN(C3)CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C20H22FN5O/c21-18-5-4-14-11-16(18)17-12-23-26-9-6-19(24-20(17)26)22-7-10-25-8-2-1-3-15(13-25)27-14/h4-6,9,11-12,15H,1-3,7-8,10,13H2,(H,22,24)/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410718 (US10377772, Compound N19) Show SMILES CN1CCN2CCCC[C@H]2COc2ccc(F)c(c2)-c2cnn3ccc1nc23 |r| Show InChI InChI=1S/C21H24FN5O/c1-25-10-11-26-8-3-2-4-15(26)14-28-16-5-6-19(22)17(12-16)18-13-23-27-9-7-20(25)24-21(18)27/h5-7,9,12-13,15H,2-4,8,10-11,14H2,1H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410719 (US10377772, Compound N20) Show SMILES Fc1ccc2OC[C@@H]3CNCCN3CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C19H21FN6O/c20-17-2-1-14-9-15(17)16-11-23-26-6-3-18(24-19(16)26)22-5-8-25-7-4-21-10-13(25)12-27-14/h1-3,6,9,11,13,21H,4-5,7-8,10,12H2,(H,22,24)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410720 (US10377772, Compound N21) Show SMILES Fc1ccc2NC[C@@H]3CCCN3CCOc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C19H20FN5O/c20-17-4-3-13-10-15(17)16-12-22-25-7-5-18(23-19(16)25)26-9-8-24-6-1-2-14(24)11-21-13/h3-5,7,10,12,14,21H,1-2,6,8-9,11H2/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410721 (US10377772, Compound N22) Show SMILES Fc1ccc2OC[C@@H]3COCCN3CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C19H20FN5O2/c20-17-2-1-14-9-15(17)16-10-22-25-5-3-18(23-19(16)25)21-4-6-24-7-8-26-11-13(24)12-27-14/h1-3,5,9-10,13H,4,6-8,11-12H2,(H,21,23)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410722 (US10377772, Compound N23) Show SMILES CN1CCN2CCNc3ccn4ncc(-c5cc(OC[C@@H]2C1)ccc5F)c4n3 |r| Show InChI InChI=1S/C20H23FN6O/c1-25-8-9-26-7-5-22-19-4-6-27-20(24-19)17(11-23-27)16-10-15(2-3-18(16)21)28-13-14(26)12-25/h2-4,6,10-11,14H,5,7-9,12-13H2,1H3,(H,22,24)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410723 (US10377772, Compound N24) Show SMILES CN1CCN2CCN(C)c3ccn4ncc(-c5cc(OC[C@@H]2C1)ccc5F)c4n3 |r| Show InChI InChI=1S/C21H25FN6O/c1-25-7-9-27-10-8-26(2)20-5-6-28-21(24-20)18(12-23-28)17-11-16(3-4-19(17)22)29-14-15(27)13-25/h3-6,11-12,15H,7-10,13-14H2,1-2H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410724 (US10377772, Compound N25) Show SMILES CN1CCN2CCOC[C@H]2COc2ccc(F)c(c2)-c2cnn3ccc1nc23 |r| Show InChI InChI=1S/C20H22FN5O2/c1-24-6-7-25-8-9-27-12-14(25)13-28-15-2-3-18(21)16(10-15)17-11-22-26-5-4-19(24)23-20(17)26/h2-5,10-11,14H,6-9,12-13H2,1H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410725 (US10377772, Compound N26) Show SMILES Fc1cc(Cl)c2OC[C@@H]3CCCN3CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C19H19ClFN5O/c20-15-9-16(21)13-8-17(15)27-11-12-2-1-5-25(12)7-4-22-18-3-6-26-19(24-18)14(13)10-23-26/h3,6,8-10,12H,1-2,4-5,7,11H2,(H,22,24)/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410726 (US10377772, Compound N27) Show SMILES Fc1ccc2OC[C@@H]3CN4CCC[C@@H]4CN3CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C22H25FN6O/c23-20-4-3-17-10-18(20)19-11-25-29-8-5-21(26-22(19)29)24-6-9-28-12-15-2-1-7-27(15)13-16(28)14-30-17/h3-5,8,10-11,15-16H,1-2,6-7,9,12-14H2,(H,24,26)/t15-,16+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410727 (US10377772, Compound N28) Show SMILES Fc1ccc2O[C@@H]3CNCCN(C3)CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C19H21FN6O/c20-17-2-1-13-9-15(17)16-11-23-26-6-3-18(24-19(16)26)22-5-8-25-7-4-21-10-14(12-25)27-13/h1-3,6,9,11,14,21H,4-5,7-8,10,12H2,(H,22,24)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410728 (US10377772, Compound N29) Show SMILES CN1CCN2C[C@H]3CCCN3C[C@H]2COc2ccc(F)c(c2)-c2cnn3ccc1nc23 |r| Show InChI InChI=1S/C23H27FN6O/c1-27-9-10-29-13-16-3-2-7-28(16)14-17(29)15-31-18-4-5-21(24)19(11-18)20-12-25-30-8-6-22(27)26-23(20)30/h4-6,8,11-12,16-17H,2-3,7,9-10,13-15H2,1H3/t16-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410729 (US10377772, Compound N30) Show SMILES Fc1ccc2OC[C@H]3CN4CCC[C@@H]4CN3CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C22H25FN6O/c23-20-4-3-17-10-18(20)19-11-25-29-8-5-21(26-22(19)29)24-6-9-28-12-15-2-1-7-27(15)13-16(28)14-30-17/h3-5,8,10-11,15-16H,1-2,6-7,9,12-14H2,(H,24,26)/t15-,16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410730 (US10377772, Compound N31) Show SMILES CN1CCN2C[C@@H]3CCCN3C[C@@H](C2)Oc2ccc(F)c(c2)-c2cnn3ccc1nc23 |r| Show InChI InChI=1S/C23H27FN6O/c1-27-9-10-28-13-16-3-2-7-29(16)15-18(14-28)31-17-4-5-21(24)19(11-17)20-12-25-30-8-6-22(27)26-23(20)30/h4-6,8,11-12,16,18H,2-3,7,9-10,13-15H2,1H3/t16-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410731 (US10377772, Compound N32) Show SMILES CC(=O)N1CCN2CCNc3ccn4ncc(-c5cc(OC[C@@H]2C1)ccc5F)c4n3 |r| Show InChI InChI=1S/C21H23FN6O2/c1-14(29)27-9-8-26-7-5-23-20-4-6-28-21(25-20)18(11-24-28)17-10-16(2-3-19(17)22)30-13-15(26)12-27/h2-4,6,10-11,15H,5,7-9,12-13H2,1H3,(H,23,25)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410732 (US10377772, Compound N33) Show SMILES Fc1ccc2OC3CCN(CC3)CCNc3ccn4ncc(-c1c2)c4n3 |(5.09,1.17,;4,.08,;4.4,-1.41,;3.31,-2.5,;1.82,-2.1,;.73,-3.19,;-2.51,-4.35,;-4,-4.75,;-5.09,-3.66,;-4.69,-2.18,;-3.2,-1.78,;-2.11,-2.87,;-4.69,-.64,;-3.35,.13,;-3.35,1.67,;-2.02,2.44,;-2.02,3.98,;-.69,4.75,;.65,3.98,;2.11,4.46,;3.02,3.21,;2.11,1.97,;2.51,.48,;1.42,-.61,;.65,2.44,;-.69,1.67,)| Show InChI InChI=1S/C19H20FN5O/c20-17-2-1-14-11-15(17)16-12-22-25-9-5-18(23-19(16)25)21-6-10-24-7-3-13(26-14)4-8-24/h1-2,5,9,11-13H,3-4,6-8,10H2,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410733 (US10377772, Compound N34) Show SMILES CN1CCN2CCC(CC2)Oc2ccc(F)c(c2)-c2cnn3ccc1nc23 |(-4.69,2.44,;-3.35,1.67,;-3.35,.13,;-4.69,-.64,;-4.69,-2.18,;-5.09,-3.66,;-4,-4.75,;-2.51,-4.35,;-2.11,-2.87,;-3.2,-1.78,;.73,-3.19,;1.82,-2.1,;3.31,-2.5,;4.4,-1.41,;4,.08,;5.09,1.17,;2.51,.48,;1.42,-.61,;2.11,1.97,;3.02,3.21,;2.11,4.46,;.65,3.98,;-.69,4.75,;-2.02,3.98,;-2.02,2.44,;-.69,1.67,;.65,2.44,)| Show InChI InChI=1S/C20H22FN5O/c1-24-10-11-25-7-4-14(5-8-25)27-15-2-3-18(21)16(12-15)17-13-22-26-9-6-19(24)23-20(17)26/h2-3,6,9,12-14H,4-5,7-8,10-11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410734 (US10377772, Compound N35) Show SMILES Fc1ccc2OC[C@H]3CNCCN3CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C19H21FN6O/c20-17-2-1-14-9-15(17)16-11-23-26-6-3-18(24-19(16)26)22-5-8-25-7-4-21-10-13(25)12-27-14/h1-3,6,9,11,13,21H,4-5,7-8,10,12H2,(H,22,24)/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410735 (US10377772, Compound N36) Show SMILES CN1CCN2CCNc3ccn4ncc(-c5cc(OC[C@H]2C1)ccc5F)c4n3 |r| Show InChI InChI=1S/C20H23FN6O/c1-25-8-9-26-7-5-22-19-4-6-27-20(24-19)17(11-23-27)16-10-15(2-3-18(16)21)28-13-14(26)12-25/h2-4,6,10-11,14H,5,7-9,12-13H2,1H3,(H,22,24)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410736 (US10377772, Compound N37) Show SMILES Fc1ccc2OC[C@@H]3CCCN3CCCc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C20H21FN4O/c21-19-6-5-16-11-17(19)18-12-22-25-10-7-14(23-20(18)25)3-1-8-24-9-2-4-15(24)13-26-16/h5-7,10-12,15H,1-4,8-9,13H2/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410737 (US10377772, Compound N38) Show SMILES Fc1ccc2OC[C@@H]3CN4CCC[C@H]4CN3CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C22H25FN6O/c23-20-4-3-17-10-18(20)19-11-25-29-8-5-21(26-22(19)29)24-6-9-28-12-15-2-1-7-27(15)13-16(28)14-30-17/h3-5,8,10-11,15-16H,1-2,6-7,9,12-14H2,(H,24,26)/t15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410739 (US10377772, Compound N40) Show SMILES C[C@H]1C[C@@H]2CCN1CCNc1ccn3ncc(-c4cc(O2)ccc4F)c3n1 |r| Show InChI InChI=1S/C20H22FN5O/c1-13-10-15-4-7-25(13)9-6-22-19-5-8-26-20(24-19)17(12-23-26)16-11-14(27-15)2-3-18(16)21/h2-3,5,8,11-13,15H,4,6-7,9-10H2,1H3,(H,22,24)/t13-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410740 (US10377772, Compound N41) Show SMILES Fc1ccc2OC[C@@H]3C=CCCN3CCNc3ccn4ncc(-c1c2)c4n3 |r,c:8| Show InChI InChI=1S/C20H20FN5O/c21-18-5-4-15-11-16(18)17-12-23-26-9-6-19(24-20(17)26)22-7-10-25-8-2-1-3-14(25)13-27-15/h1,3-6,9,11-12,14H,2,7-8,10,13H2,(H,22,24)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410741 (US10377772, Compound N42) Show SMILES CN1CCN2C[C@@H]3CCCN3C[C@H]2COc2ccc(F)c(c2)-c2cnn3ccc1nc23 |r| Show InChI InChI=1S/C23H27FN6O/c1-27-9-10-29-13-16-3-2-7-28(16)14-17(29)15-31-18-4-5-21(24)19(11-18)20-12-25-30-8-6-22(27)26-23(20)30/h4-6,8,11-12,16-17H,2-3,7,9-10,13-15H2,1H3/t16-,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410742 (US10377772, Compound N43) Show SMILES Fc1ccc2O[C@@H]3CN4CCC[C@H]4CN(C3)CCNc3ccn4ncc(-c1c2)c4n3 |r| Show InChI InChI=1S/C22H25FN6O/c23-20-4-3-16-10-18(20)19-11-25-29-8-5-21(26-22(19)29)24-6-9-27-12-15-2-1-7-28(15)14-17(13-27)30-16/h3-5,8,10-11,15,17H,1-2,6-7,9,12-14H2,(H,24,26)/t15-,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410743 (US10377772, Compound N44) Show SMILES CN1CCN2C[C@@H]3CCCN3C[C@H](C2)Oc2ccc(F)c(c2)-c2cnn3ccc1nc23 |r| Show InChI InChI=1S/C23H27FN6O/c1-27-9-10-28-13-16-3-2-7-29(16)15-18(14-28)31-17-4-5-21(24)19(11-17)20-12-25-30-8-6-22(27)26-23(20)30/h4-6,8,11-12,16,18H,2-3,7,9-10,13-15H2,1H3/t16-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410744 (US10377772, Compound N45) Show SMILES C[C@@H]1CN2CCNc3ccn4ncc(-c5cc(OC[C@@H]2CN1)ccc5F)c4n3 |r| Show InChI InChI=1S/C20H23FN6O/c1-13-11-26-7-5-22-19-4-6-27-20(25-19)17(10-24-27)16-8-15(2-3-18(16)21)28-12-14(26)9-23-13/h2-4,6,8,10,13-14,23H,5,7,9,11-12H2,1H3,(H,22,25)/t13-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410745 (US10377772, Compound N46) Show SMILES C[C@@H]1CN2CCNc3ccn4ncc(-c5cc(OC[C@@H]2CN1C)ccc5F)c4n3 |r| Show InChI InChI=1S/C21H25FN6O/c1-14-11-27-8-6-23-20-5-7-28-21(25-20)18(10-24-28)17-9-16(3-4-19(17)22)29-13-15(27)12-26(14)2/h3-5,7,9-10,14-15H,6,8,11-13H2,1-2H3,(H,23,25)/t14-,15+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410746 (US10377772, Compound N47) Show SMILES C[C@@H]1CN2CCNc3ccn4ncc(-c5cc(OC[C@@H]2CN1C1CC1)ccc5F)c4n3 |r| Show InChI InChI=1S/C23H27FN6O/c1-15-12-28-9-7-25-22-6-8-30-23(27-22)20(11-26-30)19-10-18(4-5-21(19)24)31-14-17(28)13-29(15)16-2-3-16/h4-6,8,10-11,15-17H,2-3,7,9,12-14H2,1H3,(H,25,27)/t15-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410747 (US10377772, Compound N48) Show SMILES CCCN1C[C@H]2COc3ccc(F)c(c3)-c3cnn4ccc(NCCN2C[C@H]1C)nc34 |r| Show InChI InChI=1S/C23H29FN6O/c1-3-8-28-14-17-15-31-18-4-5-21(24)19(11-18)20-12-26-30-9-6-22(27-23(20)30)25-7-10-29(17)13-16(28)2/h4-6,9,11-12,16-17H,3,7-8,10,13-15H2,1-2H3,(H,25,27)/t16-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410748 (US10377772, Compound N49) Show SMILES C[C@@H]1CN2CCNc3ccn4ncc(-c5cc(OC[C@@H]2CN1CC1CC1)ccc5F)c4n3 |r| Show InChI InChI=1S/C24H29FN6O/c1-16-12-29-9-7-26-23-6-8-31-24(28-23)21(11-27-31)20-10-19(4-5-22(20)25)32-15-18(29)14-30(16)13-17-2-3-17/h4-6,8,10-11,16-18H,2-3,7,9,12-15H2,1H3,(H,26,28)/t16-,18+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410749 (US10377772, Compound N50) Show SMILES CCN1C[C@H]2COc3ccc(F)c(c3)-c3cnn4ccc(NCCN2C[C@H]1C)nc34 |r| Show InChI InChI=1S/C22H27FN6O/c1-3-27-13-16-14-30-17-4-5-20(23)18(10-17)19-11-25-29-8-6-21(26-22(19)29)24-7-9-28(16)12-15(27)2/h4-6,8,10-11,15-16H,3,7,9,12-14H2,1-2H3,(H,24,26)/t15-,16+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410750 (US10377772, Compound N51) Show SMILES CC(C)[C@H]1CN2C[C@@H](CN1)Oc1ccc(F)c(c1)-c1cnn3ccc(NCC2)nc13 |r| Show InChI InChI=1S/C22H27FN6O/c1-14(2)20-13-28-8-6-24-21-5-7-29-22(27-21)18(11-26-29)17-9-15(3-4-19(17)23)30-16(12-28)10-25-20/h3-5,7,9,11,14,16,20,25H,6,8,10,12-13H2,1-2H3,(H,24,27)/t16-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410751 (US10377772, Compound N52) Show SMILES Fc1ccc2OC[C@@H]3CCCN3CCNc3ccc4ncc(-c1c2)n4n3 |r| Show InChI InChI=1S/C19H20FN5O/c20-16-4-3-14-10-15(16)17-11-22-19-6-5-18(23-25(17)19)21-7-9-24-8-1-2-13(24)12-26-14/h3-6,10-11,13H,1-2,7-9,12H2,(H,21,23)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410752 (US10377772, Compound N53) Show SMILES C[C@H]1CN2CCNc3ccn4ncc(-c5cc(OC[C@@H]2CN1)ccc5F)c4n3 |r| Show InChI InChI=1S/C20H23FN6O/c1-13-11-26-7-5-22-19-4-6-27-20(25-19)17(10-24-27)16-8-15(2-3-18(16)21)28-12-14(26)9-23-13/h2-4,6,8,10,13-14,23H,5,7,9,11-12H2,1H3,(H,22,25)/t13-,14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
					More data for this Ligand-Target Pair

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