Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Similar to alpha-tubulin isoform 1 (Bos taurus) | BDBM50139772![]() (22-oxovincaleukoblastine | leurocristine | vincris...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UPR 9023 CNRS Curated by ChEMBL | Assay Description In vitro inhibition of tubulin polymerization measured as turbidity formed by centrifugation | J Med Chem 41: 1524-30 (1998) Article DOI: 10.1021/jm970800t BindingDB Entry DOI: 10.7270/Q2MW2KV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Similar to alpha-tubulin isoform 1 (Bos taurus) | BDBM50216333![]() (CHEBI:67357 | DOLASTATIN-10 | Dolastatin 10 | Dolo...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UPR 9023 CNRS Curated by ChEMBL | Assay Description In vitro inhibition of tubulin polymerization measured as turbidity formed by centrifugation | J Med Chem 41: 1524-30 (1998) Article DOI: 10.1021/jm970800t BindingDB Entry DOI: 10.7270/Q2MW2KV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin alpha-1A chain (Sus scrofa (Pig)) | BDBM50216333![]() (CHEBI:67357 | DOLASTATIN-10 | Dolastatin 10 | Dolo...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire des M£canismes Mol£culaires des Communications Cellulaires (CNRS UPR 9023) Curated by ChEMBL | Assay Description Compound was tested in vitro for inhibition of tubulin polymerization. | Bioorg Med Chem Lett 8: 2855-8 (1999) BindingDB Entry DOI: 10.7270/Q2H41RX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Similar to alpha-tubulin isoform 1 (Bos taurus) | BDBM50472222![]() (CHEMBL608244) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UPR 9023 CNRS Curated by ChEMBL | Assay Description In vitro inhibition of tubulin polymerization measured as turbidity formed by centrifugation | J Med Chem 41: 1524-30 (1998) Article DOI: 10.1021/jm970800t BindingDB Entry DOI: 10.7270/Q2MW2KV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Similar to alpha-tubulin isoform 1 (Bos taurus) | BDBM50472221![]() (CHEMBL37030) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UPR 9023 CNRS Curated by ChEMBL | Assay Description In vitro inhibition of tubulin polymerization measured as turbidity formed by centrifugation | J Med Chem 41: 1524-30 (1998) Article DOI: 10.1021/jm970800t BindingDB Entry DOI: 10.7270/Q2MW2KV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Similar to alpha-tubulin isoform 1 (Bos taurus) | BDBM50472220![]() (Dolastatin 15 | Dolostatin 15) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UPR 9023 CNRS Curated by ChEMBL | Assay Description In vitro inhibition of tubulin polymerization measured as turbidity formed by centrifugation | J Med Chem 41: 1524-30 (1998) Article DOI: 10.1021/jm970800t BindingDB Entry DOI: 10.7270/Q2MW2KV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin alpha-1A chain (Sus scrofa (Pig)) | BDBM50072182![]() ((2S,5S,6R,7S,14R,15S,18S,21S,22R)-2-Benzyl-15-((S)...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire des M£canismes Mol£culaires des Communications Cellulaires (CNRS UPR 9023) Curated by ChEMBL | Assay Description Compound was tested in vitro for inhibition of tubulin polymerization | Bioorg Med Chem Lett 8: 2855-8 (1999) BindingDB Entry DOI: 10.7270/Q2H41RX7 | |||||||||||
More data for this Ligand-Target Pair |