Found 101 hits with Last Name = 'mosset' and Initial = 'p' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human)) | BDBM50592423
(CHEMBL4434865) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human)) | BDBM50592424
(CHEMBL4567314) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human)) | BDBM50592426
(CHEMBL4547253)Show SMILES Fc1ccc(CN2CCC(CC2)n2cc(Cc3ccc(Br)cc3)nn2)cc1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human)) | BDBM50592427
(CHEMBL4444356)Show SMILES Nc1ccc(CN2CCC(CC2)n2cc(Cc3ccc(Br)cc3)nn2)cc1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50064947
(CHEMBL76895 | N-(1-Benzyl-piperidin-4-yl)-2-phenyl...)Show InChI InChI=1S/C20H24N2O/c23-20(15-17-7-3-1-4-8-17)21-19-11-13-22(14-12-19)16-18-9-5-2-6-10-18/h1-10,19H,11-16H2,(H,21,23) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50592424
(CHEMBL4567314) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50592426
(CHEMBL4547253)Show SMILES Fc1ccc(CN2CCC(CC2)n2cc(Cc3ccc(Br)cc3)nn2)cc1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Similars
| DrugBank
PDB
Article
PubMed
| 8 | -43.0 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM28681
(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50059227
(1-Benzyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperidine |...)Show InChI InChI=1S/C21H23N3/c1-3-7-17(8-4-1)16-24-13-11-19(12-14-24)21-15-20(22-23-21)18-9-5-2-6-10-18/h1-10,15,19H,11-14,16H2,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50592425
(CHEMBL4435399)Show SMILES [O-][N+](=O)c1ccc(CN2CCC(CC2)n2cc(Cc3ccc(Br)cc3)nn2)cc1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human)) | BDBM50592425
(CHEMBL4435399)Show SMILES [O-][N+](=O)c1ccc(CN2CCC(CC2)n2cc(Cc3ccc(Br)cc3)nn2)cc1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50592427
(CHEMBL4444356)Show SMILES Nc1ccc(CN2CCC(CC2)n2cc(Cc3ccc(Br)cc3)nn2)cc1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 144 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50592423
(CHEMBL4434865) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233176
(Sodium 8-hydroxy-8-(2-octyloxy-quinolin-3-yl)-oct-...)Show SMILES CCCCCCCCOc1nc2ccccc2cc1C(O)CC#CCCCC([O-])=O Show InChI InChI=1S/C25H33NO4/c1-2-3-4-5-8-13-18-30-25-21(19-20-14-11-12-15-22(20)26-25)23(27)16-9-6-7-10-17-24(28)29/h11-12,14-15,19,23,27H,2-5,7-8,10,13,16-18H2,1H3,(H,28,29)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 378 | -34.1 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172823
(8-Hydroxy-8-(2-pentyloxy-phenyl)-octanoic acid met...)Show InChI InChI=1S/C20H32O4/c1-3-4-11-16-24-19-14-10-9-12-17(19)18(21)13-7-5-6-8-15-20(22)23-2/h9-10,12,14,18,21H,3-8,11,13,15-16H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 515 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172805
(9-Hydroxy-9-(3-pentyloxy-naphthalen-2-yl)-nonanoic...)Show InChI InChI=1S/C25H36O4/c1-3-4-12-17-29-24-19-21-14-11-10-13-20(21)18-22(24)23(26)15-8-6-5-7-9-16-25(27)28-2/h10-11,13-14,18-19,23,26H,3-9,12,15-17H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 579 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233183
(Sodium 8-hydroxy-8-(6-methoxy-2-pentyloxy-quinolin...)Show SMILES CCCCCOc1nc2ccc(OC)cc2cc1C(O)CC#CCCCC([O-])=O Show InChI InChI=1S/C23H29NO5/c1-3-4-9-14-29-23-19(21(25)10-7-5-6-8-11-22(26)27)16-17-15-18(28-2)12-13-20(17)24-23/h12-13,15-16,21,25H,3-4,6,8-11,14H2,1-2H3,(H,26,27)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 583 | -33.1 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172816
(8-Hydroxy-8-(3-pentyloxy-naphthalen-2-yl)-oct-5-yn...)Show InChI InChI=1S/C24H30O4/c1-3-4-11-16-28-23-18-20-13-10-9-12-19(20)17-21(23)22(25)14-7-5-6-8-15-24(26)27-2/h9-10,12-13,17-18,22,25H,3-4,6,8,11,14-16H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 695 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172806
((E)-8-Hydroxy-8-(3-pentyloxy-naphthalen-2-yl)-oct-...)Show InChI InChI=1S/C24H32O4/c1-3-4-11-16-28-23-18-20-13-10-9-12-19(20)17-21(23)22(25)14-7-5-6-8-15-24(26)27-2/h5,7,9-10,12-13,17-18,22,25H,3-4,6,8,11,14-16H2,1-2H3/b7-5+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 718 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172802
(CHEMBL383607 | Sodium 8-hydroxy-8-(2-pentyloxy-qui...)Show InChI InChI=1S/C22H27NO4/c1-2-3-10-15-27-22-18(16-17-11-8-9-12-19(17)23-22)20(24)13-6-4-5-7-14-21(25)26/h8-9,11-12,16,20,24H,2-3,5,7,10,13-15H2,1H3,(H,25,26)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 947 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172802
(CHEMBL383607 | Sodium 8-hydroxy-8-(2-pentyloxy-qui...)Show InChI InChI=1S/C22H27NO4/c1-2-3-10-15-27-22-18(16-17-11-8-9-12-19(17)23-22)20(24)13-6-4-5-7-14-21(25)26/h8-9,11-12,16,20,24H,2-3,5,7,10,13-15H2,1H3,(H,25,26)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 947 | -32.0 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172810
(CHEMBL199121 | Sodium; 8-hydroxy-8-(3-pentyloxy-na...)Show InChI InChI=1S/C23H32O4/c1-2-3-10-15-27-22-17-19-12-9-8-11-18(19)16-20(22)21(24)13-6-4-5-7-14-23(25)26/h8-9,11-12,16-17,21,24H,2-7,10,13-15H2,1H3,(H,25,26)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 969 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172817
(8-Hydroxy-8-(2-pentyloxy-phenyl)-oct-5-ynoic acid ...)Show InChI InChI=1S/C20H28O4/c1-3-4-11-16-24-19-14-10-9-12-17(19)18(21)13-7-5-6-8-15-20(22)23-2/h9-10,12,14,18,21H,3-4,6,8,11,13,15-16H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233180
(Sodium [5-hydroxy-5-(2-pentyloxy-quinolin-3-yl)-pe...)Show InChI InChI=1S/C21H25NO5/c1-2-3-7-13-27-21-17(14-16-9-4-5-10-18(16)22-21)19(23)11-6-8-12-26-15-20(24)25/h4-5,9-10,14,19,23H,2-3,7,11-13,15H2,1H3,(H,24,25)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.93E+3 | -30.3 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233181
(Sodium [5-hydroxy-5-(2-methoxy-quinolin-3-yl)-pent...)Show InChI InChI=1S/C17H17NO5/c1-22-17-13(10-12-6-2-3-7-14(12)18-17)15(19)8-4-5-9-23-11-16(20)21/h2-3,6-7,10,15,19H,8-9,11H2,1H3,(H,20,21)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 3.81E+3 | -28.8 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172822
(CHEMBL198163 | Sodium; 8-hydroxy-8-(3-pentyloxy-na...)Show InChI InChI=1S/C23H28O4/c1-2-3-10-15-27-22-17-19-12-9-8-11-18(19)16-20(22)21(24)13-6-4-5-7-14-23(25)26/h8-9,11-12,16-17,21,24H,2-3,5,7,10,13-15H2,1H3,(H,25,26)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50592423
(CHEMBL4434865) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50592423
(CHEMBL4434865) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172818
(CHEMBL196261 | Sodium; 8-hydroxy-8-(2-pentyloxy-ph...)Show InChI InChI=1S/C19H30O4/c1-2-3-10-15-23-18-13-9-8-11-16(18)17(20)12-6-4-5-7-14-19(21)22/h8-9,11,13,17,20H,2-7,10,12,14-15H2,1H3,(H,21,22)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233173
(8-Hydroxy-8-[2-(3-methoxy-propoxy)-quinolin-3-yl]-...)Show InChI InChI=1S/C22H27NO5/c1-26-14-9-15-28-22-18(16-17-10-7-8-11-19(17)23-22)20(24)12-5-3-4-6-13-21(25)27-2/h7-8,10-11,16,20,24H,4,6,9,12-15H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | >-26.5 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233174
(8-Hydroxy-8-[2-(4,4,4-trifluoro-butoxy)-quinolin-3...)Show SMILES COC(=O)CCCC#CCC(O)c1cc2ccccc2nc1OCCCC(F)(F)F Show InChI InChI=1S/C22H24F3NO4/c1-29-20(28)12-5-3-2-4-11-19(27)17-15-16-9-6-7-10-18(16)26-21(17)30-14-8-13-22(23,24)25/h6-7,9-10,15,19,27H,3,5,8,11-14H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | >-26.5 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233175
(Sodium 8-hydroxy-8-(2-methoxy-quinolin-3-yl)-oct-5...)Show InChI InChI=1S/C18H19NO4/c1-23-18-14(12-13-8-6-7-9-15(13)19-18)16(20)10-4-2-3-5-11-17(21)22/h6-9,12,16,20H,3,5,10-11H2,1H3,(H,21,22)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | >-26.5 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233177
(Sodium 8-hydroxy-8-[2-(3-methoxy-propoxy)-quinolin...)Show InChI InChI=1S/C21H25NO5/c1-26-13-8-14-27-21-17(15-16-9-6-7-10-18(16)22-21)19(23)11-4-2-3-5-12-20(24)25/h6-7,9-10,15,19,23H,3,5,8,11-14H2,1H3,(H,24,25)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | >-26.5 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233178
(Sodium 8-hydroxy-8-[2-(4,4,4-trifluoro-butoxy)-qui...)Show SMILES OC(CC#CCCCC([O-])=O)c1cc2ccccc2nc1OCCCC(F)(F)F Show InChI InChI=1S/C21H22F3NO4/c22-21(23,24)12-7-13-29-20-16(14-15-8-5-6-9-17(15)25-20)18(26)10-3-1-2-4-11-19(27)28/h5-6,8-9,14,18,26H,2,4,7,10-13H2,(H,27,28)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | >-26.5 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233179
(8-Hydroxy-8-(2-pentyloxy-quinolin-3-yl)-oct-5-ynoi...)Show InChI InChI=1S/C24H32N2O4/c1-2-3-10-17-30-24-20(18-19-11-8-9-12-21(19)26-24)22(28)13-6-4-5-7-14-23(29)25-15-16-27/h8-9,11-12,18,22,27-28H,2-3,5,7,10,13-17H2,1H3,(H,25,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | >-26.5 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233182
(8-Hydroxy-8-(2-pentyloxy-benzo[h]quinolin-3-yl)-oc...)Show SMILES CCCCCOc1nc2c(ccc3ccccc23)cc1C(O)CC#CCCCC(=O)OC Show InChI InChI=1S/C27H31NO4/c1-3-4-11-18-32-27-23(24(29)14-7-5-6-8-15-25(30)31-2)19-21-17-16-20-12-9-10-13-22(20)26(21)28-27/h9-10,12-13,16-17,19,24,29H,3-4,6,8,11,14-15,18H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | >-26.5 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233184
(Sodium 8-hydroxy-8-(2-pentyloxy-benzo[h]quinolin-3...)Show SMILES CCCCCOc1nc2c(ccc3ccccc23)cc1C(O)CC#CCCCC([O-])=O Show InChI InChI=1S/C26H29NO4/c1-2-3-10-17-31-26-22(23(28)13-6-4-5-7-14-24(29)30)18-20-16-15-19-11-8-9-12-21(19)25(20)27-26/h8-9,11-12,15-16,18,23,28H,2-3,5,7,10,13-14,17H2,1H3,(H,29,30)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | >-26.5 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172808
(8-Hydroxy-8-(2-pentyloxy-pyridin-3-yl)-octanoic ac...)Show InChI InChI=1S/C19H31NO4/c1-3-4-9-15-24-19-16(11-10-14-20-19)17(21)12-7-5-6-8-13-18(22)23-2/h10-11,14,17,21H,3-9,12-13,15H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172814
(8-Hydroxy-8-(2-pentyloxy-pyridin-3-yl)-oct-5-ynoic...)Show InChI InChI=1S/C19H27NO4/c1-3-4-9-15-24-19-16(11-10-14-20-19)17(21)12-7-5-6-8-13-18(22)23-2/h10-11,14,17,21H,3-4,6,8-9,12-13,15H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172809
(CHEMBL199172 | Sodium; 8-hydroxy-8-(2-pentyloxy-py...)Show InChI InChI=1S/C18H25NO4/c1-2-3-8-14-23-18-15(10-9-13-19-18)16(20)11-6-4-5-7-12-17(21)22/h9-10,13,16,20H,2-3,5,7-8,11-12,14H2,1H3,(H,21,22)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172813
(8-Hydroxy-8-(2-pentyloxy-quinolin-3-yl)-oct-5-ynoi...)Show InChI InChI=1S/C23H29NO4/c1-3-4-11-16-28-23-19(17-18-12-9-10-13-20(18)24-23)21(25)14-7-5-6-8-15-22(26)27-2/h9-10,12-13,17,21,25H,3-4,6,8,11,14-16H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172804
(CHEMBL198034 | Sodium; 8-hydroxy-8-(2-pentyloxy-py...)Show InChI InChI=1S/C18H29NO4/c1-2-3-8-14-23-18-15(10-9-13-19-18)16(20)11-6-4-5-7-12-17(21)22/h9-10,13,16,20H,2-8,11-12,14H2,1H3,(H,21,22)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172820
(CHEMBL196260 | Sodium; (E)-8-hydroxy-8-(2-pentylox...)Show InChI InChI=1S/C18H27NO4/c1-2-3-8-14-23-18-15(10-9-13-19-18)16(20)11-6-4-5-7-12-17(21)22/h4,6,9-10,13,16,20H,2-3,5,7-8,11-12,14H2,1H3,(H,21,22)/p-1/b6-4+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172815
(CHEMBL370374 | Sodium; 8-hydroxy-8-(2-pentyloxy-ph...)Show InChI InChI=1S/C19H26O4/c1-2-3-10-15-23-18-13-9-8-11-16(18)17(20)12-6-4-5-7-14-19(21)22/h8-9,11,13,17,20H,2-3,5,7,10,12,14-15H2,1H3,(H,21,22)/p-1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172824
(9-Hydroxy-9-(2-pentyloxy-quinolin-3-yl)-nonanoic a...)Show InChI InChI=1S/C24H35NO4/c1-3-4-12-17-29-24-20(18-19-13-10-11-14-21(19)25-24)22(26)15-8-6-5-7-9-16-23(27)28-2/h10-11,13-14,18,22,26H,3-9,12,15-17H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172803
((E)-8-Hydroxy-8-(2-pentyloxy-pyridin-3-yl)-oct-5-e...)Show InChI InChI=1S/C19H29NO4/c1-3-4-9-15-24-19-16(11-10-14-20-19)17(21)12-7-5-6-8-13-18(22)23-2/h5,7,10-11,14,17,21H,3-4,6,8-9,12-13,15H2,1-2H3/b7-5+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR 6052
Curated by ChEMBL
| Assay Description
Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazone |
Bioorg Med Chem Lett 15: 4421-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.049
BindingDB Entry DOI: 10.7270/Q26Q1WS5 |
More data for this
Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens) | BDBM50592423
(CHEMBL4434865) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116851
BindingDB Entry DOI: 10.7270/Q2CR5ZC1 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50172813
(8-Hydroxy-8-(2-pentyloxy-quinolin-3-yl)-oct-5-ynoi...)Show InChI InChI=1S/C23H29NO4/c1-3-4-11-16-28-23-19(17-18-12-9-10-13-20(18)24-23)21(25)14-7-5-6-8-15-22(26)27-2/h9-10,12-13,17,21,25H,3-4,6,8,11,14-16H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | >-26.5 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM233172
(8-Hydroxy-8-(2-octyloxy-quinolin-3-yl)-oct-5-ynoic...)Show InChI InChI=1S/C26H35NO4/c1-3-4-5-6-9-14-19-31-26-22(20-21-15-12-13-16-23(21)27-26)24(28)17-10-7-8-11-18-25(29)30-2/h12-13,15-16,20,24,28H,3-6,8-9,11,14,17-19H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | >-26.5 | n/a | n/a | n/a | n/a | n/a | 8.2 | 4 |
Université de Rennes 1
| Assay Description
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD... |
J Enzyme Inhib Med Chem 25: 653-72 (2010)
Article DOI: 10.3109/14756360903468171
BindingDB Entry DOI: 10.7270/Q2HT2N6V |
More data for this
Ligand-Target Pair | |
Search and Browse
