Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50001885 ((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50477152 (CHEMBL393466) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.643 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]SCH-23390 from dopamine D1 receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50001885 ((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50202762 (CHEMBL238952 | N-(4-(3-(4-m-tolylpiperazin-1-yl)pr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.09 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from rat cloned 5HT2A receptor expressed in NIH-3T3-GF6 cells | Bioorg Med Chem Lett 17: 1708-12 (2007) Article DOI: 10.1016/j.bmcl.2006.12.072 BindingDB Entry DOI: 10.7270/Q2W66KFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50477152 (CHEMBL393466) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50133931 (1-(4-fluoro-phenyl)-4-(3,4,6,7,12,12a-hexahydro-1H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50202763 (1-(3-(phenylthio)propyl)-4-m-tolylpiperazine | CHE...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from rat cloned 5HT2A receptor expressed in NIH-3T3-GF6 cells | Bioorg Med Chem Lett 17: 1708-12 (2007) Article DOI: 10.1016/j.bmcl.2006.12.072 BindingDB Entry DOI: 10.7270/Q2W66KFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50202761 (CHEMBL239371 | N-(4-(3-(4-o-tolylpiperazin-1-yl)pr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 21.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from rat cloned 5HT2A receptor expressed in NIH-3T3-GF6 cells | Bioorg Med Chem Lett 17: 1708-12 (2007) Article DOI: 10.1016/j.bmcl.2006.12.072 BindingDB Entry DOI: 10.7270/Q2W66KFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50202764 (1-(3-(4-nitrophenylthio)propyl)-4-m-tolylpiperazin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 21.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from rat cloned 5HT2A receptor expressed in NIH-3T3-GF6 cells | Bioorg Med Chem Lett 17: 1708-12 (2007) Article DOI: 10.1016/j.bmcl.2006.12.072 BindingDB Entry DOI: 10.7270/Q2W66KFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50133931 (1-(4-fluoro-phenyl)-4-(3,4,6,7,12,12a-hexahydro-1H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]SCH-23390 from dopamine D1 receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50477151 (CHEMBL393622) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 92 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50477151 (CHEMBL393622) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50133931 (1-(4-fluoro-phenyl)-4-(3,4,6,7,12,12a-hexahydro-1H...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 425 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]SCH-23390 from dopamine D1 receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50477152 (CHEMBL393466) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50477150 (CHEMBL240733) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50477150 (CHEMBL240733) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat brain | Bioorg Med Chem 15: 7361-7 (2007) Article DOI: 10.1016/j.bmc.2007.07.018 BindingDB Entry DOI: 10.7270/Q251420V | |||||||||||
More data for this Ligand-Target Pair |