Compile Data Set for Download or QSAR

Found 7 hits with Last Name = 'neelamegam' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50434481 (CHEMBL2385132 | CHEMBL2385133 | CHEMBL2385134) Show SMILES CCN(Cc1cccnc1)C(=O)CN(c1ccc(OC)nc1)S(=O)(=O)c1ccccc1C Show InChI InChI=1S/C23H26N4O4S/c1-4-26(16-19-9-7-13-24-14-19)23(28)17-27(20-11-12-22(31-3)25-15-20)32(29,30)21-10-6-5-8-18(21)2/h5-15H,4,16-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Antagonist activity at OX2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 3389-92 (2013) Article DOI: 10.1016/j.bmcl.2013.03.079 BindingDB Entry DOI: 10.7270/Q279461B
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50076216 (Vabicaserin) Show SMILES [H][C@@]12CCC[C@]1([H])c1cccc3CNCCN(C2)c13 |r| Show InChI InChI=1S/C15H20N2/c1-3-11-9-16-7-8-17-10-12-4-2-5-13(12)14(6-1)15(11)17/h1,3,6,12-13,16H,2,4-5,7-10H2/t12-,13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human 5-HT2C receptor				J Med Chem 57: 1488-94 (2014) Article DOI: 10.1021/jm401802f BindingDB Entry DOI: 10.7270/Q2PC35CR
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50076245 (CHEMBL1628670 | US10544152, Cpd # 1 | WAY-163909) Show SMILES [H][C@@]12CCC[C@]1([H])c1cccc3CNCCN2c13 |r| Show InChI InChI=1S/C14H18N2/c1-3-10-9-15-7-8-16-13-6-2-4-11(13)12(5-1)14(10)16/h1,3,5,11,13,15H,2,4,6-9H2/t11-,13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human 5-HT2C receptor				J Med Chem 57: 1488-94 (2014) Article DOI: 10.1021/jm401802f BindingDB Entry DOI: 10.7270/Q2PC35CR
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50434481 (CHEMBL2385132 | CHEMBL2385133 | CHEMBL2385134) Show SMILES CCN(Cc1cccnc1)C(=O)CN(c1ccc(OC)nc1)S(=O)(=O)c1ccccc1C Show InChI InChI=1S/C23H26N4O4S/c1-4-26(16-19-9-7-13-24-14-19)23(28)17-27(20-11-12-22(31-3)25-15-20)32(29,30)21-10-6-5-8-18(21)2/h5-15H,4,16-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Antagonist activity at OX2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 3389-92 (2013) Article DOI: 10.1016/j.bmcl.2013.03.079 BindingDB Entry DOI: 10.7270/Q279461B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50434481 (CHEMBL2385132 | CHEMBL2385133 | CHEMBL2385134) Show SMILES CCN(Cc1cccnc1)C(=O)CN(c1ccc(OC)nc1)S(=O)(=O)c1ccccc1C Show InChI InChI=1S/C23H26N4O4S/c1-4-26(16-19-9-7-13-24-14-19)23(28)17-27(20-11-12-22(31-3)25-15-20)32(29,30)21-10-6-5-8-18(21)2/h5-15H,4,16-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Antagonist activity at OX1 receptor (unknown origin)				Bioorg Med Chem Lett 23: 3389-92 (2013) Article DOI: 10.1016/j.bmcl.2013.03.079 BindingDB Entry DOI: 10.7270/Q279461B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50076245 (CHEMBL1628670 | US10544152, Cpd # 1 | WAY-163909) Show SMILES [H][C@@]12CCC[C@]1([H])c1cccc3CNCCN2c13 |r| Show InChI InChI=1S/C14H18N2/c1-3-10-9-15-7-8-16-13-6-2-4-11(13)12(5-1)14(10)16/h1,3,5,11,13,15H,2,4,6-9H2/t11-,13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2C receptor assessed as stimulation of Ca2+ mobilization				J Med Chem 57: 1488-94 (2014) Article DOI: 10.1021/jm401802f BindingDB Entry DOI: 10.7270/Q2PC35CR
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50076216 (Vabicaserin) Show SMILES [H][C@@]12CCC[C@]1([H])c1cccc3CNCCN(C2)c13 |r| Show InChI InChI=1S/C15H20N2/c1-3-11-9-16-7-8-17-10-12-4-2-5-13(12)14(6-1)15(11)17/h1,3,6,12-13,16H,2,4-5,7-10H2/t12-,13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2C receptor assessed as stimulation of Ca2+ mobilization				J Med Chem 57: 1488-94 (2014) Article DOI: 10.1021/jm401802f BindingDB Entry DOI: 10.7270/Q2PC35CR
					More data for this Ligand-Target Pair