Found 26 hits with Last Name = 'el-telbany' and Initial = 'rfa' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50428286
![PNG](/data/jpeg/tenK5042/BindingDB_50428286.png) (DABRAFENIB | GSK2118436A)Show SMILES CC(C)(C)c1nc(c(s1)-c1ccnc(N)n1)-c1cccc(NS(=O)(=O)c2c(F)cccc2F)c1F Show InChI InChI=1S/C23H20F3N5O2S2/c1-23(2,3)21-30-18(19(34-21)16-10-11-28-22(27)29-16)12-6-4-9-15(17(12)26)31-35(32,33)20-13(24)7-5-8-14(20)25/h4-11,31H,1-3H3,(H2,27,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
DrugBank MCE PC cid PC sid PDB UniChem
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50563431
![PNG](/data/jpeg/tenK5056/BindingDB_50563431.png) (CHEMBL4793723)Show SMILES COc1ccc(cc1)S(=O)(=O)NCCCNc1nccc(n1)-c1[nH]c(nc1-c1ccc(F)c(O)c1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM221688
![PNG](/data/jpeg/tenK22/BindingDB_221688.png) (US10568884, Cpd 9 | US9314464, 9 | US9593100, Comp...)Show SMILES COC(=O)N[C@@H](C)CNc1nccc(n1)-c1cn(nc1-c1cc(Cl)cc(NS(C)(=O)=O)c1F)C(C)C |r| Show InChI InChI=1S/C22H27ClFN7O4S/c1-12(2)31-11-16(17-6-7-25-21(28-17)26-10-13(3)27-22(32)35-4)20(29-31)15-8-14(23)9-18(19(15)24)30-36(5,33)34/h6-9,11-13,30H,10H2,1-5H3,(H,27,32)(H,25,26,28)/t13-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50563437
![PNG](/data/jpeg/tenK5056/BindingDB_50563437.png) (Arry-614 | Pexmetinib)Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)NCc1cc(F)ccc1Oc1ccc2n(CCO)ncc2c1)C(C)(C)C | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of p38 alpha (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50563432
![PNG](/data/jpeg/tenK5056/BindingDB_50563432.png) (CHEMBL4797100)Show SMILES Oc1cc(ccc1Cl)-c1nc([nH]c1-c1ccnc(NCCCNS(=O)(=O)c2ccccc2)n1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50563427
![PNG](/data/jpeg/tenK5056/BindingDB_50563427.png) (CHEMBL4758203)Show SMILES Oc1cc(ccc1F)-c1nc([nH]c1-c1ccnc(NCCCNS(=O)(=O)c2ccccc2)n1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50173609
![PNG](/data/jpeg/tenK5017/BindingDB_50173609.png) (CHEMBL363648 | D3RKN_11 | N-[4-(2-Ethyl-4-m-tolyl-...)Show SMILES CCc1nc(c(s1)-c1ccnc(NC(=O)c2ccccc2)c1)-c1cccc(C)c1 Show InChI InChI=1S/C24H21N3OS/c1-3-21-27-22(18-11-7-8-16(2)14-18)23(29-21)19-12-13-25-20(15-19)26-24(28)17-9-5-4-6-10-17/h4-15H,3H2,1-2H3,(H,25,26,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of p38 alpha (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50563436
![PNG](/data/jpeg/tenK5056/BindingDB_50563436.png) (CHEMBL4741154)Show SMILES COc1ccc(cc1)S(=O)(=O)NCCCNc1nccc(n1)-c1[nH]c(nc1-c1ccc(Cl)c(O)c1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50563435
![PNG](/data/jpeg/tenK5056/BindingDB_50563435.png) (CHEMBL4763666)Show SMILES Cc1ccc(cc1)S(=O)(=O)NCCCNc1nccc(n1)-c1[nH]c(nc1-c1ccc(Cl)c(O)c1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50563430
![PNG](/data/jpeg/tenK5056/BindingDB_50563430.png) (CHEMBL4779919)Show SMILES Cc1ccc(cc1)S(=O)(=O)NCCCNc1nccc(n1)-c1[nH]c(nc1-c1ccc(F)c(O)c1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50563434
![PNG](/data/jpeg/tenK5056/BindingDB_50563434.png) (CHEMBL4795144)Show SMILES Oc1cc(ccc1Cl)-c1nc([nH]c1-c1ccnc(NCCCNS(=O)(=O)c2cccc(F)c2)n1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50563433
![PNG](/data/jpeg/tenK5056/BindingDB_50563433.png) (CHEMBL4756408)Show SMILES Oc1cc(ccc1Cl)-c1nc([nH]c1-c1ccnc(NCCCNS(=O)(=O)c2ccc(Br)cc2)n1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50563428
![PNG](/data/jpeg/tenK5056/BindingDB_50563428.png) (CHEMBL4755378)Show SMILES Oc1cc(ccc1F)-c1nc([nH]c1-c1ccnc(NCCCNS(=O)(=O)c2ccc(Br)cc2)n1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50563429
![PNG](/data/jpeg/tenK5056/BindingDB_50563429.png) (CHEMBL4794140)Show SMILES Oc1cc(ccc1F)-c1nc([nH]c1-c1ccnc(NCCCNS(=O)(=O)c2cccc(F)c2)n1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM2579
![PNG](/data/jpeg/tenK0/BindingDB_2579.png) ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human)) | BDBM50552567
![PNG](/data/jpeg/tenK5055/BindingDB_50552567.png) (CHEMBL4779114)Show SMILES Oc1ccc(cc1)S(=O)(=O)NCCNc1cc(ccn1)-c1[nH]c(nc1-c1cccc(O)c1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRAF V600E mutant (unknown origin) preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by HotSpot kinase ass... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50044784
![PNG](/data/jpeg/tenK5004/BindingDB_50044784.png) (CHEBI:79090 | SB-202190 | US10865384, Compound SB2...)Show SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of p38 alpha (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50563431
![PNG](/data/jpeg/tenK5056/BindingDB_50563431.png) (CHEMBL4793723)Show SMILES COc1ccc(cc1)S(=O)(=O)NCCCNc1nccc(n1)-c1[nH]c(nc1-c1ccc(F)c(O)c1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50230001
![PNG](/data/jpeg/tenK5023/BindingDB_50230001.png) (4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazo...)Show SMILES [O-][N+](=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C20H13FN4O2/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(8-4-15)25(26)27/h1-12H,(H,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of p38 alpha (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50563429
![PNG](/data/jpeg/tenK5056/BindingDB_50563429.png) (CHEMBL4794140)Show SMILES Oc1cc(ccc1F)-c1nc([nH]c1-c1ccnc(NCCCNS(=O)(=O)c2cccc(F)c2)n1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50563430
![PNG](/data/jpeg/tenK5056/BindingDB_50563430.png) (CHEMBL4779919)Show SMILES Cc1ccc(cc1)S(=O)(=O)NCCCNc1nccc(n1)-c1[nH]c(nc1-c1ccc(F)c(O)c1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50563427
![PNG](/data/jpeg/tenK5056/BindingDB_50563427.png) (CHEMBL4758203)Show SMILES Oc1cc(ccc1F)-c1nc([nH]c1-c1ccnc(NCCCNS(=O)(=O)c2ccccc2)n1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50563428
![PNG](/data/jpeg/tenK5056/BindingDB_50563428.png) (CHEMBL4755378)Show SMILES Oc1cc(ccc1F)-c1nc([nH]c1-c1ccnc(NCCCNS(=O)(=O)c2ccc(Br)cc2)n1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50045333
![PNG](/data/jpeg/tenK5004/BindingDB_50045333.png) (CHEBI:90705 | SB-203580)Show SMILES C[S+]([O-])c1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of p38 alpha (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50563438
![PNG](/data/jpeg/tenK5056/BindingDB_50563438.png) (CHEMBL4798964) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of p38 alpha (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50142887
![PNG](/data/jpeg/tenK5014/BindingDB_50142887.png) (1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)Show InChI InChI=1S/C15H16ClN5/c1-15(2,3)21-14-11(13(17)18-8-19-14)12(20-21)9-4-6-10(16)7-5-9/h4-8H,1-3H3,(H2,17,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q |
More data for this Ligand-Target Pair | |