BindingDB PrimarySearch

Found 24 hits with Last Name = 'chaurasia' and Initial = 's'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Rattus norvegicus (rat))	BDBM14712 ((2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)pheny...) Show SMILES CC(=O)C(C#N)C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Torino Curated by ChEMBL					Assay Description Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assay				Eur J Med Chem 46: 383-92 (2010) Article DOI: 10.1016/j.ejmech.2010.10.029 BindingDB Entry DOI: 10.7270/Q2SQ90NX
Universit£ di Torino Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM50440473 (CHEMBL2425904) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of CDK1/Cyclin B (unknown origin)				Eur J Med Chem 68: 333-8 (2013) Article DOI: 10.1016/j.ejmech.2013.07.031 BindingDB Entry DOI: 10.7270/Q2ZW1NB0
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM50440474 (CHEMBL2425903) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of CDK1/Cyclin B (unknown origin)				Eur J Med Chem 68: 333-8 (2013) Article DOI: 10.1016/j.ejmech.2013.07.031 BindingDB Entry DOI: 10.7270/Q2ZW1NB0
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50440473 (CHEMBL2425904) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of CDK5/P25 (unknown origin)				Eur J Med Chem 68: 333-8 (2013) Article DOI: 10.1016/j.ejmech.2013.07.031 BindingDB Entry DOI: 10.7270/Q2ZW1NB0
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Squalene synthase (Rattus norvegicus)	BDBM12577 (Bisphosphonate 2 \| CHEMBL997 \| JMC515594 Compound ...) Show SMILES CCCCCN(C)CCC(O)(P(O)(O)=O)P(O)(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...				Bioorg Med Chem 18: 2428-38 (2010) Article DOI: 10.1016/j.bmc.2010.02.058 BindingDB Entry DOI: 10.7270/Q2V124ZP
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50440474 (CHEMBL2425903) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	775	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of CDK5/P25 (unknown origin)				Eur J Med Chem 68: 333-8 (2013) Article DOI: 10.1016/j.ejmech.2013.07.031 BindingDB Entry DOI: 10.7270/Q2ZW1NB0
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50440473 (CHEMBL2425904) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	875	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of CDK9/CyclinT (unknown origin)				Eur J Med Chem 68: 333-8 (2013) Article DOI: 10.1016/j.ejmech.2013.07.031 BindingDB Entry DOI: 10.7270/Q2ZW1NB0
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM50440474 (CHEMBL2425903) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of CDK7/Cyclin H (unknown origin)				Eur J Med Chem 68: 333-8 (2013) Article DOI: 10.1016/j.ejmech.2013.07.031 BindingDB Entry DOI: 10.7270/Q2ZW1NB0
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM50440473 (CHEMBL2425904) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of CDK7/Cyclin H (unknown origin)				Eur J Med Chem 68: 333-8 (2013) Article DOI: 10.1016/j.ejmech.2013.07.031 BindingDB Entry DOI: 10.7270/Q2ZW1NB0
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Rattus norvegicus (rat))	BDBM50054601 (5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazole...) Show SMILES Cc1oncc1C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Torino Curated by ChEMBL					Assay Description Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assay				Eur J Med Chem 46: 383-92 (2010) Article DOI: 10.1016/j.ejmech.2010.10.029 BindingDB Entry DOI: 10.7270/Q2SQ90NX
Universit£ di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50440474 (CHEMBL2425903) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of CDK9/CyclinT (unknown origin)				Eur J Med Chem 68: 333-8 (2013) Article DOI: 10.1016/j.ejmech.2013.07.031 BindingDB Entry DOI: 10.7270/Q2ZW1NB0
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM5566 (2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidin...) Show SMILES Nc1nc(N)c(N=O)c(OCC2CCCCC2)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of CDK1/Cyclin B (unknown origin)				Eur J Med Chem 68: 333-8 (2013) Article DOI: 10.1016/j.ejmech.2013.07.031 BindingDB Entry DOI: 10.7270/Q2ZW1NB0
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Squalene synthase (Rattus norvegicus)	BDBM50315414 ((5-(4-Phenylsulfonylfurazan-3-yloxy)-1-hydroxypent...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...				Bioorg Med Chem 18: 2428-38 (2010) Article DOI: 10.1016/j.bmc.2010.02.058 BindingDB Entry DOI: 10.7270/Q2V124ZP
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Squalene synthase (Rattus norvegicus)	BDBM50315415 ((5-(3-Phenylsulfonylfuroxan-4-yloxy)-1-hydroxypent...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...				Bioorg Med Chem 18: 2428-38 (2010) Article DOI: 10.1016/j.bmc.2010.02.058 BindingDB Entry DOI: 10.7270/Q2V124ZP
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Rattus norvegicus (rat))	BDBM50335631 (2-Nitro-3-oxo-3-[(4-trifluoromethyl)phenyl]aminopr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Torino Curated by ChEMBL					Assay Description Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assay				Eur J Med Chem 46: 383-92 (2010) Article DOI: 10.1016/j.ejmech.2010.10.029 BindingDB Entry DOI: 10.7270/Q2SQ90NX
Universit£ di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Squalene synthase (Rattus norvegicus)	BDBM50315412 (5-(4-Phenylfurazan-3-yloxy)pentylidenebis(phosphon...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...				Bioorg Med Chem 18: 2428-38 (2010) Article DOI: 10.1016/j.bmc.2010.02.058 BindingDB Entry DOI: 10.7270/Q2V124ZP
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Squalene synthase (Rattus norvegicus)	BDBM50315413 (5-(3-Phenylfuroxan-4-yloxy)pentylidenebis(phosphon...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...				Bioorg Med Chem 18: 2428-38 (2010) Article DOI: 10.1016/j.bmc.2010.02.058 BindingDB Entry DOI: 10.7270/Q2V124ZP
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Rattus norvegicus (rat))	BDBM50335629 (2-Nitro-3-oxo-3-(biphenyl-4-yl)aminopropionitrile ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Torino Curated by ChEMBL					Assay Description Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assay				Eur J Med Chem 46: 383-92 (2010) Article DOI: 10.1016/j.ejmech.2010.10.029 BindingDB Entry DOI: 10.7270/Q2SQ90NX
Universit£ di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50277785 (4'-Amino-6'-methylsulfanyl-[1,1';2',1'']terphenyl-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin)				Bioorg Med Chem Lett 19: 2158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.02.118 BindingDB Entry DOI: 10.7270/Q28G8KKM
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Rattus norvegicus (rat))	BDBM50335630 (2-Hydroxyimino-3-oxo-3-[4-(trifluoromethyl)phenyl]...) Show SMILES FC(F)(F)c1ccc(NC(=O)C(N=O)C#N)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Torino Curated by ChEMBL					Assay Description Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assay				Eur J Med Chem 46: 383-92 (2010) Article DOI: 10.1016/j.ejmech.2010.10.029 BindingDB Entry DOI: 10.7270/Q2SQ90NX
Universit£ di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50277825 (4'-Amino-4,4''-dimethoxy-6'-methylsulfanyl-[1,1';2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin)				Bioorg Med Chem Lett 19: 2158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.02.118 BindingDB Entry DOI: 10.7270/Q28G8KKM
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Rattus norvegicus (rat))	BDBM50335632 (2-Nitro-3-(4-nitrophenyl)amino-3-oxopropionitrile ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Torino Curated by ChEMBL					Assay Description Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assay				Eur J Med Chem 46: 383-92 (2010) Article DOI: 10.1016/j.ejmech.2010.10.029 BindingDB Entry DOI: 10.7270/Q2SQ90NX
Universit£ di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Glucose-6-phosphatase catalytic subunit 1 (Homo sapiens (Human))	BDBM50277824 (4'-Amino-4-fluoro-2'',4''-dimethoxy-6'-methylsulfa...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of glucose-6-phosphatase (unknown origin)				Bioorg Med Chem Lett 19: 2158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.02.118 BindingDB Entry DOI: 10.7270/Q28G8KKM
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50277823 (4'-Amino-4''-methoxy-6'-methylsulfanyl-[1,1';2',1'...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin)				Bioorg Med Chem Lett 19: 2158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.02.118 BindingDB Entry DOI: 10.7270/Q28G8KKM
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair