Compile Data Set for Download or QSAR

Found 533 hits with Last Name = 'maeda' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451408 (US10710967, Example 2) Show SMILES CC(C)(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(-c2ccsc2)c(C#N)c(=O)[nH]1 Show InChI InChI=1S/C21H19ClN4O2S/c1-21(2,3)20(28)24-10-12-4-5-16(22)14(8-12)18-25-17(13-6-7-29-11-13)15(9-23)19(27)26-18/h4-8,11H,10H2,1-3H3,(H,24,28)(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0100	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451407 (US10710967, Example 1) Show SMILES CC(C)(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(-c2ccc(Cl)cc2F)c(C#N)c(=O)[nH]1 Show InChI InChI=1S/C23H19Cl2FN4O2/c1-23(2,3)22(32)28-11-12-4-7-17(25)15(8-12)20-29-19(16(10-27)21(31)30-20)14-6-5-13(24)9-18(14)26/h4-9H,11H2,1-3H3,(H,28,32)(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451438 (US10710967, Example 20) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(OC(F)F)cc1 Show InChI InChI=1S/C22H20ClF2N3O3/c1-12(2)21(30)26-11-13-3-8-17(23)16(9-13)20-27-18(10-19(29)28-20)14-4-6-15(7-5-14)31-22(24)25/h3-10,12,22H,11H2,1-2H3,(H,26,30)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451427 (US10710967, Example 22) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1sccc1F Show InChI InChI=1S/C19H17ClFN3O2S/c1-10(2)19(26)22-9-11-3-4-13(20)12(7-11)18-23-15(8-16(25)24-18)17-14(21)5-6-27-17/h3-8,10H,9H2,1-2H3,(H,22,26)(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451477 (US10710967, Example 74) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(cc1)C1CC1 Show InChI InChI=1S/C24H24ClN3O2/c1-14(2)24(30)26-13-15-3-10-20(25)19(11-15)23-27-21(12-22(29)28-23)18-8-6-17(7-9-18)16-4-5-16/h3,6-12,14,16H,4-5,13H2,1-2H3,(H,26,30)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451447 (US10710967, Example 43) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1cnc(s1)C(F)(F)F Show InChI InChI=1S/C19H16ClF3N4O2S/c1-9(2)17(29)24-7-10-3-4-12(20)11(5-10)16-26-13(6-15(28)27-16)14-8-25-18(30-14)19(21,22)23/h3-6,8-9H,7H2,1-2H3,(H,24,29)(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451418 (US10710967, Example 12) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C21H18ClF3N4O2/c1-11(2)20(31)27-9-12-3-5-15(22)14(7-12)19-28-17(8-18(30)29-19)16-6-4-13(10-26-16)21(23,24)25/h3-8,10-11H,9H2,1-2H3,(H,27,31)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451429 (US10710967, Example 24) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C22H19ClF3N3O3/c1-12(2)21(31)27-11-13-3-8-17(23)16(9-13)20-28-18(10-19(30)29-20)14-4-6-15(7-5-14)32-22(24,25)26/h3-10,12H,11H2,1-2H3,(H,27,31)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451409 (US10710967, Example 3) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(-c2ccsc2)c(C#N)c(=O)[nH]1 Show InChI InChI=1S/C20H17ClN4O2S/c1-11(2)19(26)23-9-12-3-4-16(21)14(7-12)18-24-17(13-5-6-28-10-13)15(8-22)20(27)25-18/h3-7,10-11H,9H2,1-2H3,(H,23,26)(H,24,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451413 (US10710967, Example 7) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(Cl)cn1 Show InChI InChI=1S/C20H18Cl2N4O2/c1-11(2)20(28)24-9-12-3-5-15(22)14(7-12)19-25-17(8-18(27)26-19)16-6-4-13(21)10-23-16/h3-8,10-11H,9H2,1-2H3,(H,24,28)(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451449 (US10710967, Example 45) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(OC(F)F)nc1 Show InChI InChI=1S/C21H19ClF2N4O3/c1-11(2)20(30)26-9-12-3-5-15(22)14(7-12)19-27-16(8-17(29)28-19)13-4-6-18(25-10-13)31-21(23)24/h3-8,10-11,21H,9H2,1-2H3,(H,26,30)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451558 (US10710967, Example 157) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1ccc(OCC2CC2)nc1 Show InChI InChI=1S/C24H24ClFN4O3/c1-13(2)24(32)28-11-16-5-7-17(25)21(22(16)26)23-29-18(9-19(31)30-23)15-6-8-20(27-10-15)33-12-14-3-4-14/h5-10,13-14H,3-4,11-12H2,1-2H3,(H,28,32)(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.780	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451423 (US10710967, Example 17) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(OC(F)(F)F)cc1F Show InChI InChI=1S/C22H18ClF4N3O3/c1-11(2)21(32)28-10-12-3-6-16(23)15(7-12)20-29-18(9-19(31)30-20)14-5-4-13(8-17(14)24)33-22(25,26)27/h3-9,11H,10H2,1-2H3,(H,28,32)(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.860	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451426 (US10710967, Example 21) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C22H19ClF3N3O2/c1-12(2)21(31)27-11-13-3-8-17(23)16(9-13)20-28-18(10-19(30)29-20)14-4-6-15(7-5-14)22(24,25)26/h3-10,12H,11H2,1-2H3,(H,27,31)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.880	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451642 (US10710967, Example 240) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1nc(cs1)C#CC1CC1 Show InChI InChI=1S/C23H20ClFN4O2S/c1-12(2)22(31)26-10-14-6-8-16(24)19(20(14)25)21-28-17(9-18(30)29-21)23-27-15(11-32-23)7-5-13-3-4-13/h6,8-9,11-13H,3-4,10H2,1-2H3,(H,26,31)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451635 (US10710967, Example 233) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1cnc(s1)C#CC1CC1 Show InChI InChI=1S/C23H20ClFN4O2S/c1-12(2)23(31)27-10-14-6-7-15(24)20(21(14)25)22-28-16(9-18(30)29-22)17-11-26-19(32-17)8-5-13-3-4-13/h6-7,9,11-13H,3-4,10H2,1-2H3,(H,27,31)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451658 (US10710967, Example 256) Show SMILES CC#Cc1ccc(cn1)-c1cc(=O)[nH]c(n1)-c1c(Cl)ccc(CNC(=O)C(C)C)c1F Show InChI InChI=1S/C23H20ClFN4O2/c1-4-5-16-8-6-14(11-26-16)18-10-19(30)29-22(28-18)20-17(24)9-7-15(21(20)25)12-27-23(31)13(2)3/h6-11,13H,12H2,1-3H3,(H,27,31)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451625 (US10710967, Example 223) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1ccc(cc1)C#N Show InChI InChI=1S/C22H18ClFN4O2/c1-12(2)22(30)26-11-15-7-8-16(23)19(20(15)24)21-27-17(9-18(29)28-21)14-5-3-13(10-25)4-6-14/h3-9,12H,11H2,1-2H3,(H,26,30)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451623 (US10710967, Example 221) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1ccc(nc1)C#CC1CC1 Show InChI InChI=1S/C25H22ClFN4O2/c1-14(2)25(33)29-13-17-7-10-19(26)22(23(17)27)24-30-20(11-21(32)31-24)16-6-9-18(28-12-16)8-5-15-3-4-15/h6-7,9-12,14-15H,3-4,13H2,1-2H3,(H,29,33)(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451616 (US10710967, Example 215 | US10710967, Example 291) Show SMILES CC(C)C(=O)NCc1ccc(c(c1)-c1nc(cc(=O)[nH]1)-c1cnc(OCC2CC2)nc1)C(F)(F)F Show InChI InChI=1S/C24H24F3N5O3/c1-13(2)22(34)28-9-15-5-6-18(24(25,26)27)17(7-15)21-31-19(8-20(33)32-21)16-10-29-23(30-11-16)35-12-14-3-4-14/h5-8,10-11,13-14H,3-4,9,12H2,1-2H3,(H,28,34)(H,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451563 (US10710967, Example 162) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C21H17ClF4N4O2/c1-10(2)20(32)28-8-11-3-5-13(22)17(18(11)23)19-29-15(7-16(31)30-19)14-6-4-12(9-27-14)21(24,25)26/h3-7,9-10H,8H2,1-2H3,(H,28,32)(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451603 (US10710967, Example 203) Show SMILES CC(C)C(=O)NCc1ccc(c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(OCCC(F)(F)F)nc1)C(F)(F)F Show InChI InChI=1S/C24H22F6N4O3/c1-13(2)22(36)32-11-14-3-5-17(24(28,29)30)16(9-14)21-33-18(10-19(35)34-21)15-4-6-20(31-12-15)37-8-7-23(25,26)27/h3-6,9-10,12-13H,7-8,11H2,1-2H3,(H,32,36)(H,33,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451602 (US10710967, Example 202) Show SMILES CC(C)C(=O)NCc1ccc(c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(OCC(F)(F)F)nc1)C(F)(F)F Show InChI InChI=1S/C23H20F6N4O3/c1-12(2)21(35)31-9-13-3-5-16(23(27,28)29)15(7-13)20-32-17(8-18(34)33-20)14-4-6-19(30-10-14)36-11-22(24,25)26/h3-8,10,12H,9,11H2,1-2H3,(H,31,35)(H,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451593 (US10710967, Example 193) Show SMILES CC#Cc1cncc(c1)-c1cc(=O)[nH]c(n1)-c1cc(CNC(=O)C(C)C)ccc1Cl Show InChI InChI=1S/C23H21ClN4O2/c1-4-5-15-8-17(13-25-11-15)20-10-21(29)28-22(27-20)18-9-16(6-7-19(18)24)12-26-23(30)14(2)3/h6-11,13-14H,12H2,1-3H3,(H,26,30)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451592 (US10710967, Example 192) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1cncc(c1)C#C Show InChI InChI=1S/C22H19ClN4O2/c1-4-14-7-16(12-24-10-14)19-9-20(28)27-21(26-19)17-8-15(5-6-18(17)23)11-25-22(29)13(2)3/h1,5-10,12-13H,11H2,2-3H3,(H,25,29)(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451591 (US10710967, Example 191) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1nc(cs1)C(F)(F)F Show InChI InChI=1S/C19H15ClF4N4O2S/c1-8(2)17(30)25-6-9-3-4-10(20)14(15(9)21)16-26-11(5-13(29)28-16)18-27-12(7-31-18)19(22,23)24/h3-5,7-8H,6H2,1-2H3,(H,25,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451637 (US10710967, Example 235) Show SMILES CCC1(COc2ccc(cn2)-c2cc(=O)[nH]c(n2)-c2cc(CNC(=O)C(C)C)ccc2Cl)COC1 Show InChI InChI=1S/C26H29ClN4O4/c1-4-26(13-34-14-26)15-35-23-8-6-18(12-28-23)21-10-22(32)31-24(30-21)19-9-17(5-7-20(19)27)11-29-25(33)16(2)3/h5-10,12,16H,4,11,13-15H2,1-3H3,(H,29,33)(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451657 (US10710967, Example 255) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1ccc(cn1)C#CC1CC1 Show InChI InChI=1S/C25H22ClFN4O2/c1-14(2)25(33)29-13-17-8-9-18(26)22(23(17)27)24-30-20(11-21(32)31-24)19-10-7-16(12-28-19)6-5-15-3-4-15/h7-12,14-15H,3-4,13H2,1-2H3,(H,29,33)(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451640 (US10710967, Example 238) Show SMILES CC#Cc1csc(n1)-c1cc(=O)[nH]c(n1)-c1c(Cl)ccc(CNC(=O)C(C)C)c1F Show InChI InChI=1S/C21H18ClFN4O2S/c1-4-5-13-10-30-21(25-13)15-8-16(28)27-19(26-15)17-14(22)7-6-12(18(17)23)9-24-20(29)11(2)3/h6-8,10-11H,9H2,1-3H3,(H,24,29)(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451639 (US10710967, Example 237) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1nc(C)cs1 Show InChI InChI=1S/C19H18ClFN4O2S/c1-9(2)18(27)22-7-11-4-5-12(20)15(16(11)21)17-24-13(6-14(26)25-17)19-23-10(3)8-28-19/h4-6,8-9H,7H2,1-3H3,(H,22,27)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451579 (US10710967, Example 178) Show SMILES CC(C)C(=O)NCc1ccc(F)c(c1Cl)-c1nc(cc(=O)[nH]1)-c1ccc(OCC(F)F)nc1 Show InChI InChI=1S/C22H20ClF3N4O3/c1-11(2)22(32)28-9-13-3-5-14(24)19(20(13)23)21-29-15(7-17(31)30-21)12-4-6-18(27-8-12)33-10-16(25)26/h3-8,11,16H,9-10H2,1-2H3,(H,28,32)(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451683 (US10710967, Example 278) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1ccc(OCCOCC(F)(F)F)nc1 Show InChI InChI=1S/C24H23ClF4N4O4/c1-13(2)23(35)31-11-15-3-5-16(25)20(21(15)26)22-32-17(9-18(34)33-22)14-4-6-19(30-10-14)37-8-7-36-12-24(27,28)29/h3-6,9-10,13H,7-8,11-12H2,1-2H3,(H,31,35)(H,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451686 (US10710967, Example 281) Show SMILES CCCC(=O)NCc1ccc(c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(cn1)C#CC1CC1)C(F)(F)F Show InChI InChI=1S/C26H23F3N4O2/c1-2-3-23(34)31-15-18-8-10-20(26(27,28)29)19(12-18)25-32-22(13-24(35)33-25)21-11-9-17(14-30-21)7-6-16-4-5-16/h8-14,16H,2-5,15H2,1H3,(H,31,34)(H,32,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451687 (US10710967, Example 282) Show SMILES CCCC(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1ccc(cn1)C#CC1CC1 Show InChI InChI=1S/C25H22ClFN4O2/c1-2-3-21(32)29-14-17-9-10-18(26)23(24(17)27)25-30-20(12-22(33)31-25)19-11-8-16(13-28-19)7-6-15-4-5-15/h8-13,15H,2-5,14H2,1H3,(H,29,32)(H,30,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451690 (US10710967, Example 285) Show SMILES CC(C)CC#Cc1ncc(cn1)-c1cc(=O)[nH]c(n1)-c1cc(CNC(=O)C(C)C)ccc1C(F)(F)F Show InChI InChI=1S/C26H26F3N5O2/c1-15(2)6-5-7-22-30-13-18(14-31-22)21-11-23(35)34-24(33-21)19-10-17(12-32-25(36)16(3)4)8-9-20(19)26(27,28)29/h8-11,13-16H,6,12H2,1-4H3,(H,32,36)(H,33,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451693 (US10710967, Example 288) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1cnc(OCC2CC2)cn1 Show InChI InChI=1S/C23H23ClFN5O3/c1-12(2)23(32)28-8-14-5-6-15(24)20(21(14)25)22-29-16(7-18(31)30-22)17-9-27-19(10-26-17)33-11-13-3-4-13/h5-7,9-10,12-13H,3-4,8,11H2,1-2H3,(H,28,32)(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451695 (US10710967, Example 290) Show SMILES CCCC(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1cnc(OCC2CC2)nc1 Show InChI InChI=1S/C23H23ClFN5O3/c1-2-3-18(31)26-9-14-6-7-16(24)20(21(14)25)22-29-17(8-19(32)30-22)15-10-27-23(28-11-15)33-12-13-4-5-13/h6-8,10-11,13H,2-5,9,12H2,1H3,(H,26,31)(H,29,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451697 (US10710967, Example 292) Show SMILES CC#Cc1ncc(s1)-c1cc(=O)[nH]c(n1)-c1c(Cl)ccc(CNC(=O)C(C)C)c1F Show InChI InChI=1S/C21H18ClFN4O2S/c1-4-5-17-24-10-15(30-17)14-8-16(28)27-20(26-14)18-13(22)7-6-12(19(18)23)9-25-21(29)11(2)3/h6-8,10-11H,9H2,1-3H3,(H,25,29)(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451699 (US10710967, Example 294) Show SMILES CC(C)C(=O)NCc1ccc(F)c(c1F)-c1nc(cc(=O)[nH]1)-c1ccc(cn1)C#CC1CC1 Show InChI InChI=1S/C25H22F2N4O2/c1-14(2)25(33)29-13-17-8-9-18(26)22(23(17)27)24-30-20(11-21(32)31-24)19-10-7-16(12-28-19)6-5-15-3-4-15/h7-12,14-15H,3-4,13H2,1-2H3,(H,29,33)(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451700 (US10710967, Example 295) Show SMILES CC(C)C(=O)NCc1ccc(F)c(c1F)-c1nc(cc(=O)[nH]1)-c1ccc(nc1)C#CC1CC1 Show InChI InChI=1S/C25H22F2N4O2/c1-14(2)25(33)29-13-17-7-10-19(26)22(23(17)27)24-30-20(11-21(32)31-24)16-6-9-18(28-12-16)8-5-15-3-4-15/h6-7,9-12,14-15H,3-4,13H2,1-2H3,(H,29,33)(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451705 (US10710967, Example 300) Show SMILES CCCOCCOc1ccc(cn1)-c1cc(=O)[nH]c(n1)-c1c(F)c(CNC(=O)C(C)C)ccc1C(F)(F)F Show InChI InChI=1S/C26H28F4N4O4/c1-4-9-37-10-11-38-21-8-6-16(13-31-21)19-12-20(35)34-24(33-19)22-18(26(28,29)30)7-5-17(23(22)27)14-32-25(36)15(2)3/h5-8,12-13,15H,4,9-11,14H2,1-3H3,(H,32,36)(H,33,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451707 (US10710967, Example 302) Show SMILES CC(C)C(=O)NCc1ccc(c(c1F)-c1nc(cc(=O)[nH]1)-c1cnc(s1)C#CC1CC1)C(F)(F)F Show InChI InChI=1S/C24H20F4N4O2S/c1-12(2)23(34)30-10-14-6-7-15(24(26,27)28)20(21(14)25)22-31-16(9-18(33)32-22)17-11-29-19(35-17)8-5-13-3-4-13/h6-7,9,11-13H,3-4,10H2,1-2H3,(H,30,34)(H,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451708 (US10710967, Example 303) Show SMILES CC(C)C(=O)NCc1ccc(c(c1F)-c1nc(cc(=O)[nH]1)-c1ccc(OCCOCC(F)(F)F)cn1)C(F)(F)F Show InChI InChI=1S/C25H23F7N4O4/c1-13(2)23(38)34-10-14-3-5-16(25(30,31)32)20(21(14)26)22-35-18(9-19(37)36-22)17-6-4-15(11-33-17)40-8-7-39-12-24(27,28)29/h3-6,9,11,13H,7-8,10,12H2,1-2H3,(H,34,38)(H,35,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451508 (US10710967, Example 105) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(OCC2CC2)nc1 Show InChI InChI=1S/C24H25ClN4O3/c1-14(2)24(31)27-11-16-5-7-19(25)18(9-16)23-28-20(10-21(30)29-23)17-6-8-22(26-12-17)32-13-15-3-4-15/h5-10,12,14-15H,3-4,11,13H2,1-2H3,(H,27,31)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451441 (US10710967, Example 37) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(C)c(F)c1 Show InChI InChI=1S/C22H21ClFN3O2/c1-12(2)22(29)25-11-14-5-7-17(23)16(8-14)21-26-19(10-20(28)27-21)15-6-4-13(3)18(24)9-15/h4-10,12H,11H2,1-3H3,(H,25,29)(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451665 (US10710967, Example 263) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1F)-c1nc(cc(=O)[nH]1)-c1nc2ccccc2s1 Show InChI InChI=1S/C22H18ClFN4O2S/c1-11(2)21(30)25-10-12-7-8-13(23)18(19(12)24)20-26-15(9-17(29)28-20)22-27-14-5-3-4-6-16(14)31-22/h3-9,11H,10H2,1-2H3,(H,25,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451668 (US10710967, Example 266) Show SMILES CC(C)OCCOc1ccc(cn1)-c1cc(=O)[nH]c(n1)-c1c(F)ccc(CNC(=O)C(C)C)c1F Show InChI InChI=1S/C25H28F2N4O4/c1-14(2)25(33)29-13-17-5-7-18(26)22(23(17)27)24-30-19(11-20(32)31-24)16-6-8-21(28-12-16)35-10-9-34-15(3)4/h5-8,11-12,14-15H,9-10,13H2,1-4H3,(H,29,33)(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451467 (US10710967, Example 63) Show SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(cc1)C#Cc1ccccn1 Show InChI InChI=1S/C28H23ClN4O2/c1-18(2)28(35)31-17-20-9-13-24(29)23(15-20)27-32-25(16-26(34)33-27)21-10-6-19(7-11-21)8-12-22-5-3-4-14-30-22/h3-7,9-11,13-16,18H,17H2,1-2H3,(H,31,35)(H,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451529 (US10710967, Example 127) Show SMILES CC(C)C(=O)NCc1ccc(c(c1)-c1nc(cc(=O)[nH]1)-c1cncc(C)c1)C(F)(F)F Show InChI InChI=1S/C22H21F3N4O2/c1-12(2)21(31)27-10-14-4-5-17(22(23,24)25)16(7-14)20-28-18(8-19(30)29-20)15-6-13(3)9-26-11-15/h4-9,11-12H,10H2,1-3H3,(H,27,31)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM451481 (US10710967, Example 78) Show SMILES CCOc1ccc(cn1)-c1cc(=O)[nH]c(n1)-c1cc(CNC(=O)C(C)C)ccc1C(F)(F)F Show InChI InChI=1S/C23H23F3N4O3/c1-4-33-20-8-6-15(12-27-20)18-10-19(31)30-21(29-18)16-9-14(11-28-22(32)13(2)3)5-7-17(16)23(24,25)26/h5-10,12-13H,4,11H2,1-3H3,(H,28,32)(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
ASKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...				US Patent US10710967 (2020) BindingDB Entry DOI: 10.7270/Q2NZ8BP9
					More data for this Ligand-Target Pair

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