Found 4976 hits with Last Name = 'shepard' and Initial = 's' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM272571
(US10065963, Compound 32a | US10376513, Example 345...)Show SMILES CCOc1c(cc(Cl)c(F)c1[C@@H]1CNC(=O)C1)[C@@H](C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C20H22ClFN6O2/c1-4-30-18-12(6-13(21)17(22)16(18)11-5-14(29)24-7-11)10(3)28-20-15(9(2)27-28)19(23)25-8-26-20/h6,8,10-11H,4-5,7H2,1-3H3,(H,24,29)(H2,23,25,26)/t10-,11+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| US Patent
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation
US Patent
| Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... |
US Patent US10065963 (2018)
BindingDB Entry DOI: 10.7270/Q2H41TFS |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM272574
(US10065963, Compound 32d | US10376513, Example 348...)Show SMILES CCOc1c(cc(Cl)c(F)c1[C@H]1CNC(=O)C1)[C@H](C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C20H22ClFN6O2/c1-4-30-18-12(6-13(21)17(22)16(18)11-5-14(29)24-7-11)10(3)28-20-15(9(2)27-28)19(23)25-8-26-20/h6,8,10-11H,4-5,7H2,1-3H3,(H,24,29)(H2,23,25,26)/t10-,11+/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| US Patent
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation
US Patent
| Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... |
US Patent US10065963 (2018)
BindingDB Entry DOI: 10.7270/Q2H41TFS |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM272573
(US10065963, 32c | US10376513, Example 346 | US1064...)Show SMILES CCOc1c(cc(Cl)c(F)c1[C@@H]1CNC(=O)C1)[C@H](C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C20H22ClFN6O2/c1-4-30-18-12(6-13(21)17(22)16(18)11-5-14(29)24-7-11)10(3)28-20-15(9(2)27-28)19(23)25-8-26-20/h6,8,10-11H,4-5,7H2,1-3H3,(H,24,29)(H2,23,25,26)/t10-,11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| US Patent
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation
US Patent
| Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... |
US Patent US10065963 (2018)
BindingDB Entry DOI: 10.7270/Q2H41TFS |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM272572
(US10065963, Compound 32b | US10376513, Example 347...)Show SMILES CCOc1c(cc(Cl)c(F)c1[C@H]1CNC(=O)C1)[C@@H](C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C20H22ClFN6O2/c1-4-30-18-12(6-13(21)17(22)16(18)11-5-14(29)24-7-11)10(3)28-20-15(9(2)27-28)19(23)25-8-26-20/h6,8,10-11H,4-5,7H2,1-3H3,(H,24,29)(H2,23,25,26)/t10-,11-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| US Patent
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | 6.7 | 25 |
Incyte Corporation
US Patent
| Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas... |
US Patent US10065963 (2018)
BindingDB Entry DOI: 10.7270/Q2H41TFS |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557219
(5-Methyl-2-(5- morpholin-4-yl-3, 4'-bipyridin-2'-y...)Show SMILES Cc1[nH]c(nc1C(=O)N[C@H]1CCOC1)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557220
(N-Benzyl-5- methyl-2-(5- morpholin-4-yl-3, 4'-bipy...)Show SMILES Cc1[nH]c(nc1C(=O)NCc1ccccc1)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557220
(N-Benzyl-5- methyl-2-(5- morpholin-4-yl-3, 4'-bipy...)Show SMILES Cc1[nH]c(nc1C(=O)NCc1ccccc1)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557221
(5-Methyl-2-(5- morpholin-4-yl-3, 4'-bipyridin-2'-y...)Show SMILES C[C@H](NC(=O)c1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1)c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557221
(5-Methyl-2-(5- morpholin-4-yl-3, 4'-bipyridin-2'-y...)Show SMILES C[C@H](NC(=O)c1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1)c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557222
(5-Methyl-2-(5- morpholin-4-yl-3, 4'-bipyridin-2'-y...)Show SMILES C[C@@H](NC(=O)c1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1)c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557222
(5-Methyl-2-(5- morpholin-4-yl-3, 4'-bipyridin-2'-y...)Show SMILES C[C@@H](NC(=O)c1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1)c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557223
(N-[(1R)-2- Methoxy-1- phenylethyl]-5- methyl-2-(5-...)Show SMILES COC[C@H](NC(=O)c1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1)c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557223
(N-[(1R)-2- Methoxy-1- phenylethyl]-5- methyl-2-(5-...)Show SMILES COC[C@H](NC(=O)c1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1)c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557224
(N-[(1S)-2- Methoxy-1- phenylethyl]-5- methyl-2-(5-...)Show SMILES COC[C@@H](NC(=O)c1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1)c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557225
(N-[1-(3- Fluorophenyl)ethyl]- 5-methyl-2-(5- morph...)Show SMILES CC(NC(=O)c1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1)c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557225
(N-[1-(3- Fluorophenyl)ethyl]- 5-methyl-2-(5- morph...)Show SMILES CC(NC(=O)c1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1)c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557226
(N-2-Adamantyl-5- methyl-2-(5- morpholin-4-yl-3, 4'...)Show SMILES Cc1[nH]c(nc1C(=O)NC1C2CC3CC(C2)CC1C3)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 |TLB:8:9:11:13.14.15,THB:13:12:9:14.16.15,13:14:9:11.12.18,16:17:11:13.14.15,16:14:11:17.9.18,(-3.83,-5.75,;-3.16,-7.14,;-3.89,-8.5,;-2.83,-9.61,;-1.44,-8.94,;-1.65,-7.42,;-.53,-6.35,;.94,-6.79,;-.9,-4.86,;.22,-3.79,;1.06,-2.32,;1.06,-.92,;2.43,-.23,;3.8,-.92,;3.8,-2.32,;2.43,-3.02,;2.96,-3.79,;1.59,-3.1,;1.59,-1.7,;-3.11,-11.12,;-4.56,-11.64,;-4.83,-13.16,;-3.66,-14.15,;-2.21,-13.64,;-1.93,-12.12,;-6.28,-13.68,;-6.56,-15.19,;-8.01,-15.71,;-9.18,-14.71,;-8.91,-13.2,;-7.46,-12.68,;-10.08,-12.2,;-11.53,-12.72,;-12.71,-11.72,;-12.43,-10.21,;-10.98,-9.69,;-9.81,-10.68,)| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557226
(N-2-Adamantyl-5- methyl-2-(5- morpholin-4-yl-3, 4'...)Show SMILES Cc1[nH]c(nc1C(=O)NC1C2CC3CC(C2)CC1C3)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 |TLB:8:9:11:13.14.15,THB:13:12:9:14.16.15,13:14:9:11.12.18,16:17:11:13.14.15,16:14:11:17.9.18,(-3.83,-5.75,;-3.16,-7.14,;-3.89,-8.5,;-2.83,-9.61,;-1.44,-8.94,;-1.65,-7.42,;-.53,-6.35,;.94,-6.79,;-.9,-4.86,;.22,-3.79,;1.06,-2.32,;1.06,-.92,;2.43,-.23,;3.8,-.92,;3.8,-2.32,;2.43,-3.02,;2.96,-3.79,;1.59,-3.1,;1.59,-1.7,;-3.11,-11.12,;-4.56,-11.64,;-4.83,-13.16,;-3.66,-14.15,;-2.21,-13.64,;-1.93,-12.12,;-6.28,-13.68,;-6.56,-15.19,;-8.01,-15.71,;-9.18,-14.71,;-8.91,-13.2,;-7.46,-12.68,;-10.08,-12.2,;-11.53,-12.72,;-12.71,-11.72,;-12.43,-10.21,;-10.98,-9.69,;-9.81,-10.68,)| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557227
(N-[(3S)-1- Benzylpyrrolidin- 3-yl]-5-methyl-2- (5-...)Show SMILES Cc1[nH]c(nc1C(=O)N[C@H]1CCN(Cc2ccccc2)C1)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557228
(N-[(3R)-1- Benzylpyrrolidin- 3-yl]-5-methyl-2- (5-...)Show SMILES Cc1[nH]c(nc1C(=O)N[C@@H]1CCN(Cc2ccccc2)C1)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557229
(5-Methyl-2-(5- morpholin-4-yl-3, 4'-bipyridin-2'-y...)Show SMILES CC1CSC(CC1NC=O)c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557229
(5-Methyl-2-(5- morpholin-4-yl-3, 4'-bipyridin-2'-y...)Show SMILES CC1CSC(CC1NC=O)c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557230
(N-(2,3-Dihydro- 1H-inden-2-yl)-5- methyl-2-(5- mor...)Show SMILES Cc1[nH]c(nc1C(=O)NC1Cc2ccccc2C1)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557230
(N-(2,3-Dihydro- 1H-inden-2-yl)-5- methyl-2-(5- mor...)Show SMILES Cc1[nH]c(nc1C(=O)NC1Cc2ccccc2C1)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557237
(N,N-Dimethyl- 1-[5-methyl-2- (5-morpholin- 4-yl-3,...)Show SMILES CN(C)Cc1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557239
(3-Methoxy-N- {[5-methyl-2- (5-morpholin- 4-yl-3,4'...)Show SMILES COCCCNCc1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557241
(US11352340, Example 294)Show SMILES Cc1nc([nH]c1C)-c1cc(ccn1)-c1cnn(Cc2ccc(Cl)cc2)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557242
(US11352340, Example 295)Show SMILES Cc1[nH]c(nc1C(=O)N[C@H]1CCOC1)-c1cc(ccn1)-c1cnn(Cc2ccc(Cl)cc2)c1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557243
(2-{-4-[1-(4- | US11352340, Example 296)Show SMILES CNC(=O)c1nc([nH]c1C)-c1cc(ccn1)-c1cnn(Cc2ccc(Cl)cc2)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557244
(US11352340, Example 297)Show SMILES Cc1[nH]c(nc1C#N)-c1cc(ccn1)-c1cnn(Cc2ccc(Cl)cc2)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557245
(US11352340, Example 298)Show SMILES Cc1cnc([nH]1)-c1cc(ccn1)-c1cncc(c1)S(=O)(=O)N[C@H]1CC[C@](C)(O)CC1 |r,wU:22.24,25.28,wD:25.29,(-.8,7.04,;-.03,5.7,;-.93,4.46,;-.03,3.21,;1.44,3.69,;1.44,5.23,;2.77,2.92,;2.77,1.38,;4.1,.61,;5.44,1.38,;5.44,2.92,;4.1,3.69,;4.1,-.93,;5.44,-1.7,;5.44,-3.24,;4.1,-4.01,;2.77,-3.24,;2.77,-1.7,;1.44,-4.01,;.67,-5.34,;2.21,-5.34,;.1,-3.24,;-1.23,-4.01,;-1.23,-5.55,;-2.56,-6.32,;-3.9,-5.55,;-5.44,-5.55,;-4.3,-7.04,;-3.9,-4.01,;-2.56,-3.24,)| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557245
(US11352340, Example 298)Show SMILES Cc1cnc([nH]1)-c1cc(ccn1)-c1cncc(c1)S(=O)(=O)N[C@H]1CC[C@](C)(O)CC1 |r,wU:22.24,25.28,wD:25.29,(-.8,7.04,;-.03,5.7,;-.93,4.46,;-.03,3.21,;1.44,3.69,;1.44,5.23,;2.77,2.92,;2.77,1.38,;4.1,.61,;5.44,1.38,;5.44,2.92,;4.1,3.69,;4.1,-.93,;5.44,-1.7,;5.44,-3.24,;4.1,-4.01,;2.77,-3.24,;2.77,-1.7,;1.44,-4.01,;.67,-5.34,;2.21,-5.34,;.1,-3.24,;-1.23,-4.01,;-1.23,-5.55,;-2.56,-6.32,;-3.9,-5.55,;-5.44,-5.55,;-4.3,-7.04,;-3.9,-4.01,;-2.56,-3.24,)| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557246
(N-((1r,4r)-4- Hydroxycyclohexyl)- 2'-(4-methyl-1H-...)Show SMILES Cc1c[nH]c(n1)-c1cc(ccn1)-c1cncc(c1)S(=O)(=O)NC1CCC(O)CC1 |(9.34,4.93,;9.34,3.39,;8.09,2.48,;8.57,1.02,;10.11,1.02,;10.58,2.48,;11.01,-.23,;10.38,-1.63,;11.29,-2.88,;12.82,-2.72,;13.45,-1.31,;12.54,-.06,;10.66,-4.29,;11.57,-5.53,;10.94,-6.94,;9.41,-7.1,;8.51,-5.85,;9.13,-4.45,;6.97,-6.01,;6.81,-4.48,;7.13,-7.55,;5.44,-6.18,;4.54,-4.93,;3.01,-5.09,;2.1,-3.84,;2.73,-2.44,;1.82,-1.19,;4.26,-2.28,;5.16,-3.52,)| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557246
(N-((1r,4r)-4- Hydroxycyclohexyl)- 2'-(4-methyl-1H-...)Show SMILES Cc1c[nH]c(n1)-c1cc(ccn1)-c1cncc(c1)S(=O)(=O)NC1CCC(O)CC1 |(9.34,4.93,;9.34,3.39,;8.09,2.48,;8.57,1.02,;10.11,1.02,;10.58,2.48,;11.01,-.23,;10.38,-1.63,;11.29,-2.88,;12.82,-2.72,;13.45,-1.31,;12.54,-.06,;10.66,-4.29,;11.57,-5.53,;10.94,-6.94,;9.41,-7.1,;8.51,-5.85,;9.13,-4.45,;6.97,-6.01,;6.81,-4.48,;7.13,-7.55,;5.44,-6.18,;4.54,-4.93,;3.01,-5.09,;2.1,-3.84,;2.73,-2.44,;1.82,-1.19,;4.26,-2.28,;5.16,-3.52,)| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557247
(US11352340, Example 300 | US11352340, Example 304)Show SMILES CS(=O)(=O)N1CCC(C1)c1c[nH]c(n1)-c1cc(ccn1)-c1cnn(Cc2ccc(Cl)cc2)c1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557254
(US11352340, Example 307)Show SMILES COc1ccccc1Nc1nc([nH]c1C)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557255
(N-[5-Methyl-2- (5-morpholin-4- yl-3,4'-bipyridin- ...)Show SMILES Cc1[nH]c(nc1Nc1ccnnc1)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM556970
(US11352340, Example 1)Show SMILES Clc1ccc(Cn2cc(cn2)-c2ccnc(c2)-c2ncc([nH]2)-c2ccccc2)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM556971
(4-(1-Benzyl-1H- pyrazol-4-yl)-2-(5- phenyl-1H-imid...)Show SMILES C(c1ccccc1)n1cc(cn1)-c1ccnc(c1)-c1ncc([nH]1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM556982
(N-(2'-(5-Phenyl-1H- imidazol-2-yl)-3,4'- bipyridin...)Show SMILES CC(=O)Nc1cncc(c1)-c1ccnc(c1)-c1ncc([nH]1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM556982
(N-(2'-(5-Phenyl-1H- imidazol-2-yl)-3,4'- bipyridin...)Show SMILES CC(=O)Nc1cncc(c1)-c1ccnc(c1)-c1ncc([nH]1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM556983
(4-(2'-(5-Phenyl-1H- imidazol-2-yl)-3,4'- bipyridin...)Show SMILES C1CN(CCO1)c1cncc(c1)-c1ccnc(c1)-c1ncc([nH]1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM556983
(4-(2'-(5-Phenyl-1H- imidazol-2-yl)-3,4'- bipyridin...)Show SMILES C1CN(CCO1)c1cncc(c1)-c1ccnc(c1)-c1ncc([nH]1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM556984
(5-Methoxy2'-(5- phenyl-1H- imidazol-2-yl)-3,4'- bi...)Show SMILES COc1cncc(c1)-c1ccnc(c1)-c1ncc([nH]1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM556984
(5-Methoxy2'-(5- phenyl-1H- imidazol-2-yl)-3,4'- bi...)Show SMILES COc1cncc(c1)-c1ccnc(c1)-c1ncc([nH]1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM556996
(5-(Methylsulfonyl)- 2'-(5-phenyl-1H- imidazol-2-yl...)Show SMILES CS(=O)(=O)c1cncc(c1)-c1ccnc(c1)-c1ncc([nH]1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM556996
(5-(Methylsulfonyl)- 2'-(5-phenyl-1H- imidazol-2-yl...)Show SMILES CS(=O)(=O)c1cncc(c1)-c1ccnc(c1)-c1ncc([nH]1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM556997
(4-(2'-(5-Phenyl-1H- imidazol-2-yl)-3,4'- bipyridin...)Show SMILES C1CN(CCO1)c1ccc(cn1)-c1ccnc(c1)-c1ncc([nH]1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM557002
(2-(5-Phenyl-1H- imidazol-2-yl)-4-(1- (tetrahydro-2...)Show SMILES C1CC(CCO1)n1cc(cn1)-c1ccnc(c1)-c1ncc([nH]1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM557028
(US11352340, Example 74)Show SMILES COc1cncc(c1)-c1ccnc(c1)-c1cnc([nH]1)-c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q24T6NKW |
More data for this Ligand-Target Pair | |