Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50478403![]() (CHEBI:23527 | CYTOCHALASIN B) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 521 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of LFA1/ICAM1-mediated CFSE-labeled TPA-stimulated human HL60 cell adhesion to ICAM1 expressing human HeLa cells after 45 mins by fluoresc... | J Nat Prod 64: 559-62 (2001) Article DOI: 10.1021/np000436s BindingDB Entry DOI: 10.7270/Q26D5WSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L (Homo sapiens (Human)) | BDBM50478403![]() (CHEBI:23527 | CYTOCHALASIN B) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysis | J Nat Prod 66: 962-7 (2003) Article DOI: 10.1021/np030086k BindingDB Entry DOI: 10.7270/Q2M61P1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50478403![]() (CHEBI:23527 | CYTOCHALASIN B) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 1.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cells | J Nat Prod 67: 772-7 (2004) Article DOI: 10.1021/np030524n BindingDB Entry DOI: 10.7270/Q24M97BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L (Homo sapiens (Human)) | BDBM50478475![]() (CHEBI:3533 | Cephaeline) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | >2.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysis | J Nat Prod 66: 962-7 (2003) Article DOI: 10.1021/np030086k BindingDB Entry DOI: 10.7270/Q2M61P1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50478733![]() (CHEBI:67606 | Sampangine) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of LFA1/ICAM1-mediated CFSE-labeled TPA-stimulated human HL60 cell adhesion to ICAM1 expressing human HeLa cells after 45 mins by fluoresc... | J Nat Prod 64: 559-62 (2001) Article DOI: 10.1021/np000436s BindingDB Entry DOI: 10.7270/Q26D5WSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50478404![]() (CHEMBL452089) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >4.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cells | J Nat Prod 67: 772-7 (2004) Article DOI: 10.1021/np030524n BindingDB Entry DOI: 10.7270/Q24M97BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50478402![]() ((+)-Oricinolide | CHEMBL480688) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cells | J Nat Prod 67: 772-7 (2004) Article DOI: 10.1021/np030524n BindingDB Entry DOI: 10.7270/Q24M97BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50478405![]() (CHEBI:66486 | NSC-266494 | Simalikalactone D) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cells | J Nat Prod 67: 772-7 (2004) Article DOI: 10.1021/np030524n BindingDB Entry DOI: 10.7270/Q24M97BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L (Homo sapiens (Human)) | BDBM50216297![]() (6',7',10,11-tetramethoxyemetan | CHEMBL50588 | Eme...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.04E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi Curated by ChEMBL | Assay Description Inhibition of LFA1:CD11a/CD18/ICAM1-mediated human HL60 cell adhesion to human HeLa cells expressing ICAM1 by fluorescence analysis | J Nat Prod 66: 962-7 (2003) Article DOI: 10.1021/np030086k BindingDB Entry DOI: 10.7270/Q2M61P1C | |||||||||||
More data for this Ligand-Target Pair |