Found 413 hits with Last Name = 'teixeira-fouchard' and Initial = 's' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593565
(CHEMBL5193039)Show SMILES Nc1ncc(nc1C(=O)NC12CCC(O)(CC1)CC2)-c1ccc(CN2CCC(CC2)N2CCOCC2)cc1Cl | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593545
(CHEMBL5182576)Show SMILES CN(C)Cc1ccc(cc1)-c1cnc(N)c(n1)C(=O)NC1CCCCC1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593559
(CHEMBL5189710)Show SMILES CC(C)N1CCN(Cc2ccc(cc2)-c2cnc(N)c(n2)C(=O)N[C@H]2CC[C@H](O)CC2)CC1 |r,wU:24.25,wD:27.29,(8.66,.77,;7.33,1.54,;7.33,3.08,;6,.77,;6,-.77,;4.66,-1.54,;3.33,-.77,;2,-1.54,;.66,-.77,;-.66,-1.53,;-2,-.77,;-2,.77,;-.67,1.54,;.66,.77,;-3.33,1.54,;-3.33,3.08,;-4.66,3.85,;-6,3.08,;-7.33,3.85,;-6,1.54,;-4.66,.78,;-7.33,.77,;-8.66,1.54,;-7.33,-.77,;-6,-1.54,;-4.66,-.77,;-3.33,-1.54,;-3.33,-3.08,;-2,-3.85,;-4.66,-3.85,;-6,-3.08,;3.33,.77,;4.66,1.54,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593565
(CHEMBL5193039)Show SMILES Nc1ncc(nc1C(=O)NC12CCC(O)(CC1)CC2)-c1ccc(CN2CCC(CC2)N2CCOCC2)cc1Cl | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593559
(CHEMBL5189710)Show SMILES CC(C)N1CCN(Cc2ccc(cc2)-c2cnc(N)c(n2)C(=O)N[C@H]2CC[C@H](O)CC2)CC1 |r,wU:24.25,wD:27.29,(8.66,.77,;7.33,1.54,;7.33,3.08,;6,.77,;6,-.77,;4.66,-1.54,;3.33,-.77,;2,-1.54,;.66,-.77,;-.66,-1.53,;-2,-.77,;-2,.77,;-.67,1.54,;.66,.77,;-3.33,1.54,;-3.33,3.08,;-4.66,3.85,;-6,3.08,;-7.33,3.85,;-6,1.54,;-4.66,.78,;-7.33,.77,;-8.66,1.54,;-7.33,-.77,;-6,-1.54,;-4.66,-.77,;-3.33,-1.54,;-3.33,-3.08,;-2,-3.85,;-4.66,-3.85,;-6,-3.08,;3.33,.77,;4.66,1.54,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593560
(CHEMBL5206645)Show SMILES CCN(CC)C1CCN(Cc2ccc(cc2)-c2cnc(N)c(n2)C(=O)N[C@H]2CC[C@H](O)CC2)CC1 |r,wU:26.27,wD:29.31,(8,3.85,;6.66,3.08,;6.66,1.54,;8,.77,;9.33,1.54,;5.33,.77,;5.33,-.77,;4,-1.54,;2.66,-.77,;1.33,-1.54,;-0,-.77,;-1.33,-1.54,;-2.67,-.77,;-2.67,.77,;-1.33,1.54,;-0,.77,;-4,1.54,;-4,3.08,;-5.33,3.85,;-6.66,3.08,;-8,3.85,;-6.66,1.54,;-5.33,.77,;-8,.77,;-9.33,1.54,;-8,-.77,;-6.66,-1.54,;-5.33,-.77,;-4,-1.54,;-4,-3.08,;-2.66,-3.85,;-5.33,-3.85,;-6.66,-3.08,;2.66,.77,;4,1.54,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593561
(CHEMBL5200388)Show SMILES Nc1ncc(nc1C(=O)N[C@H]1CC[C@H](O)CC1)-c1ccc(CN2CCC(CC2)N2CCCC2)cc1 |r,wU:10.10,wD:13.14,(-7.88,3.85,;-6.55,3.08,;-5.21,3.85,;-3.89,3.08,;-3.89,1.54,;-5.21,.78,;-6.55,1.54,;-7.88,.77,;-9.22,1.54,;-7.88,-.77,;-6.55,-1.54,;-5.21,-.77,;-3.88,-1.54,;-3.88,-3.08,;-2.55,-3.85,;-5.21,-3.85,;-6.55,-3.08,;-2.55,.77,;-2.55,-.77,;-1.21,-1.53,;.11,-.77,;1.44,-1.54,;2.78,-.77,;4.11,-1.54,;5.45,-.77,;5.45,.77,;4.11,1.54,;2.78,.77,;6.78,1.54,;8.19,.92,;9.22,2.06,;8.45,3.39,;6.94,3.07,;.11,.77,;-1.22,1.54,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593561
(CHEMBL5200388)Show SMILES Nc1ncc(nc1C(=O)N[C@H]1CC[C@H](O)CC1)-c1ccc(CN2CCC(CC2)N2CCCC2)cc1 |r,wU:10.10,wD:13.14,(-7.88,3.85,;-6.55,3.08,;-5.21,3.85,;-3.89,3.08,;-3.89,1.54,;-5.21,.78,;-6.55,1.54,;-7.88,.77,;-9.22,1.54,;-7.88,-.77,;-6.55,-1.54,;-5.21,-.77,;-3.88,-1.54,;-3.88,-3.08,;-2.55,-3.85,;-5.21,-3.85,;-6.55,-3.08,;-2.55,.77,;-2.55,-.77,;-1.21,-1.53,;.11,-.77,;1.44,-1.54,;2.78,-.77,;4.11,-1.54,;5.45,-.77,;5.45,.77,;4.11,1.54,;2.78,.77,;6.78,1.54,;8.19,.92,;9.22,2.06,;8.45,3.39,;6.94,3.07,;.11,.77,;-1.22,1.54,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593563
(CHEMBL5204737)Show SMILES Nc1ncc(nc1C(=O)N[C@H]1CC[C@H](O)CC1)-c1ccc(CN2CCC(CC2)N2CCOCC2)cc1Cl |r,wU:10.10,wD:13.14,(-8,3.85,;-6.66,3.08,;-5.33,3.85,;-4,3.08,;-4,1.54,;-5.33,.77,;-6.66,1.54,;-8,.77,;-9.33,1.54,;-8,-.77,;-6.66,-1.54,;-5.33,-.77,;-4,-1.54,;-4,-3.08,;-2.66,-3.85,;-5.33,-3.85,;-6.66,-3.08,;-2.67,.77,;-2.67,-.77,;-1.33,-1.53,;-0,-.77,;1.33,-1.54,;2.66,-.77,;4,-1.54,;5.33,-.77,;5.33,.77,;4,1.54,;2.66,.77,;6.66,1.54,;6.66,3.08,;8,3.85,;9.33,3.08,;9.33,1.54,;8,.77,;-0,.77,;-1.33,1.54,;-1.33,3.08,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593562
(CHEMBL5199857)Show SMILES Nc1ncc(nc1C(=O)N[C@H]1CC[C@H](O)CC1)-c1ccc(CN2CCC(CC2)N2CCOCC2)cc1 |r,wU:10.10,wD:13.14,(-8,3.85,;-6.66,3.08,;-5.33,3.85,;-4,3.08,;-4,1.54,;-5.33,.77,;-6.66,1.54,;-8,.77,;-9.33,1.54,;-8,-.77,;-6.66,-1.54,;-5.33,-.77,;-4,-1.54,;-4,-3.08,;-2.66,-3.85,;-5.33,-3.85,;-6.66,-3.08,;-2.67,.77,;-2.67,-.77,;-1.33,-1.54,;-0,-.77,;1.33,-1.54,;2.66,-.77,;4,-1.54,;5.33,-.77,;5.33,.77,;4,1.54,;2.66,.77,;6.66,1.54,;6.66,3.08,;8,3.85,;9.33,3.08,;9.33,1.54,;8,.77,;-0,.77,;-1.33,1.54,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499,R206H]
(Homo sapiens (Human)) | BDBM518855
(US11160797, Example 1 | US11160797, Example 26 | U...)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2N(C)C(=O)Cc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593552
(CHEMBL5206178)Show SMILES CN(C)Cc1ccc(cc1)-c1cnc(N)c(n1)C(=O)NC1CCC(O)CC1 |(5.33,.77,;5.33,-.77,;6.66,-1.54,;4,-1.54,;2.66,-.77,;1.34,-1.53,;-0,-.77,;-0,.77,;1.33,1.54,;2.66,.77,;-1.33,1.54,;-1.33,3.08,;-2.66,3.85,;-4,3.08,;-5.33,3.85,;-4,1.54,;-2.66,.78,;-5.33,.77,;-6.66,1.54,;-5.33,-.77,;-4,-1.54,;-2.66,-.77,;-1.33,-1.54,;-1.33,-3.08,;0,-3.85,;-2.66,-3.85,;-4,-3.08,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM518855
(US11160797, Example 1 | US11160797, Example 26 | U...)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2N(C)C(=O)Cc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM518855
(US11160797, Example 1 | US11160797, Example 26 | U...)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2N(C)C(=O)Cc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593558
(CHEMBL5189432)Show SMILES CC(C)N1CCN(Cc2ccc(cc2)-c2cnc(N)c(n2)C(=O)NC[C@@](C)(O)C(F)(F)F)CC1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593558
(CHEMBL5189432)Show SMILES CC(C)N1CCN(Cc2ccc(cc2)-c2cnc(N)c(n2)C(=O)NC[C@@](C)(O)C(F)(F)F)CC1 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593560
(CHEMBL5206645)Show SMILES CCN(CC)C1CCN(Cc2ccc(cc2)-c2cnc(N)c(n2)C(=O)N[C@H]2CC[C@H](O)CC2)CC1 |r,wU:26.27,wD:29.31,(8,3.85,;6.66,3.08,;6.66,1.54,;8,.77,;9.33,1.54,;5.33,.77,;5.33,-.77,;4,-1.54,;2.66,-.77,;1.33,-1.54,;-0,-.77,;-1.33,-1.54,;-2.67,-.77,;-2.67,.77,;-1.33,1.54,;-0,.77,;-4,1.54,;-4,3.08,;-5.33,3.85,;-6.66,3.08,;-8,3.85,;-6.66,1.54,;-5.33,.77,;-8,.77,;-9.33,1.54,;-8,-.77,;-6.66,-1.54,;-5.33,-.77,;-4,-1.54,;-4,-3.08,;-2.66,-3.85,;-5.33,-3.85,;-6.66,-3.08,;2.66,.77,;4,1.54,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593565
(CHEMBL5193039)Show SMILES Nc1ncc(nc1C(=O)NC12CCC(O)(CC1)CC2)-c1ccc(CN2CCC(CC2)N2CCOCC2)cc1Cl | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593551
(CHEMBL5173187)Show SMILES CN(C)Cc1ccc(cc1)-c1cnc(N)c(n1)C(=O)NC1CCCC1O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593551
(CHEMBL5173187)Show SMILES CN(C)Cc1ccc(cc1)-c1cnc(N)c(n1)C(=O)NC1CCCC1O | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593550
(CHEMBL5199757)Show SMILES CN(C)Cc1ccc(cc1)-c1cnc(N)c(n1)C(=O)NC[C@@](C)(O)C(F)(F)F |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593557
(CHEMBL5200140)Show SMILES C[C@@](O)(CNC(=O)c1nc(cnc1N)-c1ccc(CN2CCNCC2)cc1)C(F)(F)F |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593564
(CHEMBL5196823)Show SMILES C[C@]1(O)CC[C@@H](CC1)NC(=O)c1nc(cnc1N)-c1ccc(CN2CCC(CC2)N2CCOCC2)cc1Cl |r,wU:5.8,wD:1.1,(-2.45,-2.72,;-4,-2.72,;-3.23,-4.06,;-4,-1.18,;-5.33,-.41,;-6.66,-1.18,;-6.66,-2.72,;-5.33,-3.49,;-8,-.41,;-8,1.13,;-9.33,1.9,;-6.66,1.9,;-5.33,1.13,;-4,1.9,;-4,3.44,;-5.33,4.21,;-6.66,3.44,;-8,4.21,;-2.67,1.13,;-2.67,-.41,;-1.33,-1.18,;-0,-.41,;1.33,-1.18,;2.66,-.41,;4,-1.18,;5.33,-.41,;5.33,1.13,;4,1.9,;2.66,1.13,;6.66,1.9,;8,1.13,;9.33,1.9,;9.33,3.44,;8,4.21,;6.66,3.44,;-0,1.13,;-1.33,1.9,;-1.33,3.44,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593545
(CHEMBL5182576)Show SMILES CN(C)Cc1ccc(cc1)-c1cnc(N)c(n1)C(=O)NC1CCCCC1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499,R206H]
(Homo sapiens (Human)) | BDBM522124
(US11160797, Example 32)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2c(NC(=O)C2(C)C)c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499,R206H]
(Homo sapiens (Human)) | BDBM522113
(US11160797, Example 21)Show SMILES CC(C)N1C(=O)Cc2cc(ccc12)-c1cncc(c1)-c1ccc(=O)n(c1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593562
(CHEMBL5199857)Show SMILES Nc1ncc(nc1C(=O)N[C@H]1CC[C@H](O)CC1)-c1ccc(CN2CCC(CC2)N2CCOCC2)cc1 |r,wU:10.10,wD:13.14,(-8,3.85,;-6.66,3.08,;-5.33,3.85,;-4,3.08,;-4,1.54,;-5.33,.77,;-6.66,1.54,;-8,.77,;-9.33,1.54,;-8,-.77,;-6.66,-1.54,;-5.33,-.77,;-4,-1.54,;-4,-3.08,;-2.66,-3.85,;-5.33,-3.85,;-6.66,-3.08,;-2.67,.77,;-2.67,-.77,;-1.33,-1.54,;-0,-.77,;1.33,-1.54,;2.66,-.77,;4,-1.54,;5.33,-.77,;5.33,.77,;4,1.54,;2.66,.77,;6.66,1.54,;6.66,3.08,;8,3.85,;9.33,3.08,;9.33,1.54,;8,.77,;-0,.77,;-1.33,1.54,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499,R206H]
(Homo sapiens (Human)) | BDBM518859
(US11160797, Example 2)Show SMILES COc1cc(cn(C(C)C)c1=O)-c1cncc(c1)-c1ccc2N(C)C(=O)Cc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM522113
(US11160797, Example 21)Show SMILES CC(C)N1C(=O)Cc2cc(ccc12)-c1cncc(c1)-c1ccc(=O)n(c1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499,R206H]
(Homo sapiens (Human)) | BDBM522116
(US11160797, Example 24)Show SMILES CC(C)CN1C(=O)Cc2cc(ccc12)-c1cncc(c1)-c1ccc(=O)n(c1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM522130
(US11160797, Example 38)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2N(CC3CCC3)C(=O)Cc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499,R206H]
(Homo sapiens (Human)) | BDBM522130
(US11160797, Example 38)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2N(CC3CCC3)C(=O)Cc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499,R206H]
(Homo sapiens (Human)) | BDBM522131
(US11160797, Example 39)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2N(C)C(=O)CCCc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM522140
(US11160797, Example 48)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2N(C)S(=O)(=O)Cc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499,R206H]
(Homo sapiens (Human)) | BDBM522140
(US11160797, Example 48)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2N(C)S(=O)(=O)Cc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593561
(CHEMBL5200388)Show SMILES Nc1ncc(nc1C(=O)N[C@H]1CC[C@H](O)CC1)-c1ccc(CN2CCC(CC2)N2CCCC2)cc1 |r,wU:10.10,wD:13.14,(-7.88,3.85,;-6.55,3.08,;-5.21,3.85,;-3.89,3.08,;-3.89,1.54,;-5.21,.78,;-6.55,1.54,;-7.88,.77,;-9.22,1.54,;-7.88,-.77,;-6.55,-1.54,;-5.21,-.77,;-3.88,-1.54,;-3.88,-3.08,;-2.55,-3.85,;-5.21,-3.85,;-6.55,-3.08,;-2.55,.77,;-2.55,-.77,;-1.21,-1.53,;.11,-.77,;1.44,-1.54,;2.78,-.77,;4.11,-1.54,;5.45,-.77,;5.45,.77,;4.11,1.54,;2.78,.77,;6.78,1.54,;8.19,.92,;9.22,2.06,;8.45,3.39,;6.94,3.07,;.11,.77,;-1.22,1.54,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593561
(CHEMBL5200388)Show SMILES Nc1ncc(nc1C(=O)N[C@H]1CC[C@H](O)CC1)-c1ccc(CN2CCC(CC2)N2CCCC2)cc1 |r,wU:10.10,wD:13.14,(-7.88,3.85,;-6.55,3.08,;-5.21,3.85,;-3.89,3.08,;-3.89,1.54,;-5.21,.78,;-6.55,1.54,;-7.88,.77,;-9.22,1.54,;-7.88,-.77,;-6.55,-1.54,;-5.21,-.77,;-3.88,-1.54,;-3.88,-3.08,;-2.55,-3.85,;-5.21,-3.85,;-6.55,-3.08,;-2.55,.77,;-2.55,-.77,;-1.21,-1.53,;.11,-.77,;1.44,-1.54,;2.78,-.77,;4.11,-1.54,;5.45,-.77,;5.45,.77,;4.11,1.54,;2.78,.77,;6.78,1.54,;8.19,.92,;9.22,2.06,;8.45,3.39,;6.94,3.07,;.11,.77,;-1.22,1.54,)| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM522113
(US11160797, Example 21)Show SMILES CC(C)N1C(=O)Cc2cc(ccc12)-c1cncc(c1)-c1ccc(=O)n(c1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM522116
(US11160797, Example 24)Show SMILES CC(C)CN1C(=O)Cc2cc(ccc12)-c1cncc(c1)-c1ccc(=O)n(c1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM522116
(US11160797, Example 24)Show SMILES CC(C)CN1C(=O)Cc2cc(ccc12)-c1cncc(c1)-c1ccc(=O)n(c1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM522131
(US11160797, Example 39)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2N(C)C(=O)CCCc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM522124
(US11160797, Example 32)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2c(NC(=O)C2(C)C)c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499,R206H]
(Homo sapiens (Human)) | BDBM522117
(US11160797, Example 25)Show SMILES CCCN1C(=O)Cc2cc(ccc12)-c1cncc(c1)-c1ccc(=O)n(c1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499,R206H]
(Homo sapiens (Human)) | BDBM522065
(US11160797, Example 3)Show SMILES CC(C)n1cc(cc(C)c1=O)-c1cncc(c1)-c1ccc2N(C)C(=O)Cc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM522140
(US11160797, Example 48)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2N(C)S(=O)(=O)Cc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593546
(CHEMBL5189664) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM522124
(US11160797, Example 32)Show SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2c(NC(=O)C2(C)C)c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1
(Homo sapiens (Human)) | BDBM50593556
(CHEMBL5195256)Show SMILES C[C@@](O)(CNC(=O)c1nc(cnc1N)-c1ccc(CN2CCS(=O)(=O)CC2)cc1)C(F)(F)F |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128667 BindingDB Entry DOI: 10.7270/Q2125XN6 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499]
(Homo sapiens (Human)) | BDBM518859
(US11160797, Example 2)Show SMILES COc1cc(cn(C(C)C)c1=O)-c1cncc(c1)-c1ccc2N(C)C(=O)Cc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |
Activin receptor type-1 [172-499,R206H]
(Homo sapiens (Human)) | BDBM522136
(US11160797, Example 44)Show SMILES CC(C)n1nc(ccc1=O)-c1cncc(c1)-c1ccc2N(C)C(=O)Cc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2M048M3 |
More data for this Ligand-Target Pair | |