Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase kinase kinase kinase 2 (Homo sapiens (Human)) | BDBM50256917 (CHEMBL4084376) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a |
Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan. Curated by ChEMBL | Assay Description Binding affinity to human wild type GCK (M1 to G318 residues) expressed in mammalian expression system by KINOMEScan assay | Bioorg Med Chem Lett 27: 2144-2147 (2017) Article DOI: 10.1016/j.bmcl.2017.03.055 BindingDB Entry DOI: 10.7270/Q22F7QWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 2 (Homo sapiens (Human)) | BDBM50256930 (CHEMBL4097172) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a |
Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan. Curated by ChEMBL | Assay Description Binding affinity to human wild type GCK (M1 to G318 residues) expressed in mammalian expression system by KINOMEScan assay | Bioorg Med Chem Lett 27: 2144-2147 (2017) Article DOI: 10.1016/j.bmcl.2017.03.055 BindingDB Entry DOI: 10.7270/Q22F7QWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 2 (Homo sapiens (Human)) | BDBM50256919 (CHEMBL4103925) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a |
Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan. Curated by ChEMBL | Assay Description Binding affinity to human wild type GCK (M1 to G318 residues) expressed in mammalian expression system by KINOMEScan assay | Bioorg Med Chem Lett 27: 2144-2147 (2017) Article DOI: 10.1016/j.bmcl.2017.03.055 BindingDB Entry DOI: 10.7270/Q22F7QWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 2 (Homo sapiens (Human)) | BDBM50256918 (CHEMBL4088519) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a |
Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan. Curated by ChEMBL | Assay Description Binding affinity to human wild type GCK (M1 to G318 residues) expressed in mammalian expression system by KINOMEScan assay | Bioorg Med Chem Lett 27: 2144-2147 (2017) Article DOI: 10.1016/j.bmcl.2017.03.055 BindingDB Entry DOI: 10.7270/Q22F7QWQ | |||||||||||
More data for this Ligand-Target Pair |