Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dimer of Gag-Pol polyprotein [501-599] (Human immunodeficiency virus type 1) | BDBM32391![]() (iso-butyl-substituted sulfonamide, 9b) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | MMDB Article PubMed | 900 | -34.3 | n/a | n/a | n/a | n/a | n/a | 5.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM32389![]() (phenyl-substituted sulfonamides, 6f) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.80E+3 | -31.5 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [501-599] (Human immunodeficiency virus type 1) | BDBM32384![]() (phenyl-substituted sulfonamides, 6a) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.80E+3 | -30.7 | n/a | n/a | n/a | n/a | n/a | 5.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pepsin A (Porcine) | BDBM32387![]() (phenyl-substituted sulfonamides, 6d) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 3.90E+3 | -30.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pepsin A (Porcine) | BDBM32389![]() (phenyl-substituted sulfonamides, 6f) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 4.00E+3 | -30.8 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM32387![]() (phenyl-substituted sulfonamides, 6d) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 4.20E+3 | -30.5 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pepsin A (Porcine) | BDBM32390![]() (iso-butyl-substituted sulfonamide, 9a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 4.50E+3 | -30.5 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pepsin A (Porcine) | BDBM32391![]() (iso-butyl-substituted sulfonamide, 9b) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 4.80E+3 | -30.4 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM32392![]() (carboxamide, 12a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 5.70E+3 | -29.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pepsin A (Porcine) | BDBM32384![]() (phenyl-substituted sulfonamides, 6a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 5.70E+3 | -29.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM32391![]() (iso-butyl-substituted sulfonamide, 9b) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 6.80E+3 | -29.3 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM32384![]() (phenyl-substituted sulfonamides, 6a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 7.00E+3 | -29.2 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin IV (Plasmodium falciparum) | BDBM32387![]() (phenyl-substituted sulfonamides, 6d) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 7.50E+3 | -29.1 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin IV (Plasmodium falciparum) | BDBM32388![]() (phenyl-substituted sulfonamides, 6e) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 7.50E+3 | -29.1 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [501-599] (Human immunodeficiency virus type 1) | BDBM32387![]() (phenyl-substituted sulfonamides, 6d) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | MMDB Article PubMed | 9.60E+3 | -28.4 | n/a | n/a | n/a | n/a | n/a | 5.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [501-599] (Human immunodeficiency virus type 1) | BDBM32390![]() (iso-butyl-substituted sulfonamide, 9a) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.00E+4 | -28.3 | n/a | n/a | n/a | n/a | n/a | 5.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [501-599] (Human immunodeficiency virus type 1) | BDBM32385![]() (phenyl-substituted sulfonamides, 6b) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.40E+4 | -27.5 | n/a | n/a | n/a | n/a | n/a | 5.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pepsin A (Porcine) | BDBM32385![]() (phenyl-substituted sulfonamides, 6b) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.50E+4 | -27.5 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM32394![]() (carboxamide, 12c) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.60E+4 | -27.4 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin IV (Plasmodium falciparum) | BDBM32385![]() (phenyl-substituted sulfonamides, 6b) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.70E+4 | -27.0 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM32385![]() (phenyl-substituted sulfonamides, 6b) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.80E+4 | -26.9 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin IV (Plasmodium falciparum) | BDBM32389![]() (phenyl-substituted sulfonamides, 6f) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.00E+4 | -26.6 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM32386![]() (phenyl-substituted sulfonamides, 6c) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.10E+4 | -26.5 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM32388![]() (phenyl-substituted sulfonamides, 6e) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.20E+4 | -26.4 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM32390![]() (iso-butyl-substituted sulfonamide, 9a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.30E+4 | -26.3 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin IV (Plasmodium falciparum) | BDBM32384![]() (phenyl-substituted sulfonamides, 6a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.60E+4 | -25.2 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin IV (Plasmodium falciparum) | BDBM32386![]() (phenyl-substituted sulfonamides, 6c) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 4.20E+4 | -24.8 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin IV (Plasmodium falciparum) | BDBM32391![]() (iso-butyl-substituted sulfonamide, 9b) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 5.60E+4 | -24.3 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin IV (Plasmodium falciparum) | BDBM32393![]() (carboxamide, 12b) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 5.60E+4 | -24.3 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM32393![]() (carboxamide, 12b) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 6.30E+4 | -23.8 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 [22-457] (Homo sapiens (Human)) | BDBM32389![]() (phenyl-substituted sulfonamides, 6f) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 6.40E+4 | -23.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin IV (Plasmodium falciparum) | BDBM32390![]() (iso-butyl-substituted sulfonamide, 9a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 8.70E+4 | -23.0 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM32392![]() (carboxamide, 12a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 9.10E+4 | -22.9 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin IV (Plasmodium falciparum) | BDBM32392![]() (carboxamide, 12a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 9.80E+4 | -22.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM32394![]() (carboxamide, 12c) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.20E+5 | -22.2 | n/a | n/a | n/a | n/a | n/a | 4.5 | 23 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 [22-457] (Homo sapiens (Human)) | BDBM32386![]() (phenyl-substituted sulfonamides, 6c) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.50E+5 | -21.8 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin IV (Plasmodium falciparum) | BDBM32394![]() (carboxamide, 12c) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.70E+5 | -21.5 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Philipps-University Marburg | Assay Description Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito... | Bioorg Med Chem 16: 8574-86 (2008) Article DOI: 10.1016/j.bmc.2008.08.012 BindingDB Entry DOI: 10.7270/Q2639N2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025647![]() (CHEMBL3335148) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025645![]() (CHEMBL3335146) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025650![]() (CHEMBL3335151) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025628![]() (CHEMBL3335124) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025646![]() (CHEMBL3335147) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025644![]() (CHEMBL3335145) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025643![]() (CHEMBL3335144) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025642![]() (CHEMBL3335143) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025634![]() (CHEMBL3335125) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025653![]() (CHEMBL3335154) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025652![]() (CHEMBL3335153) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025649![]() (CHEMBL3335150) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50025640![]() (CHEMBL3335141) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay | J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712 | |||||||||||
More data for this Ligand-Target Pair |
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