Compile Data Set for Download or QSAR

Found 20 hits with Last Name = 'nambu' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533247 (CHEMBL4470356) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)[C@@H]3CS(=O)(=O)c4c3ccc(c4F)C(F)(F)F)c(-c3ccc(F)c(C)c3)n12 |r| Show InChI InChI=1S/C29H27F5N4O4S/c1-16-14-17(8-11-20(16)30)26-25(35-22-6-5-7-23(42-4)38(22)26)28(39)37(13-12-36(2)3)21-15-43(40,41)27-18(21)9-10-19(24(27)31)29(32,33)34/h5-11,14,21H,12-13,15H2,1-4H3/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533247 (CHEMBL4470356) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)[C@@H]3CS(=O)(=O)c4c3ccc(c4F)C(F)(F)F)c(-c3ccc(F)c(C)c3)n12 |r| Show InChI InChI=1S/C29H27F5N4O4S/c1-16-14-17(8-11-20(16)30)26-25(35-22-6-5-7-23(42-4)38(22)26)28(39)37(13-12-36(2)3)21-15-43(40,41)27-18(21)9-10-19(24(27)31)29(32,33)34/h5-11,14,21H,12-13,15H2,1-4H3/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533251 (CHEMBL4579540) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)[C@@H]3CS(=O)(=O)c4c3ccc(Cl)c4Cl)c(-c3ccc(F)c(C)c3)n12 |r| Show InChI InChI=1S/C28H27Cl2FN4O4S/c1-16-14-17(8-11-20(16)31)26-25(32-22-6-5-7-23(39-4)35(22)26)28(36)34(13-12-33(2)3)21-15-40(37,38)27-18(21)9-10-19(29)24(27)30/h5-11,14,21H,12-13,15H2,1-4H3/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533251 (CHEMBL4579540) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)[C@@H]3CS(=O)(=O)c4c3ccc(Cl)c4Cl)c(-c3ccc(F)c(C)c3)n12 |r| Show InChI InChI=1S/C28H27Cl2FN4O4S/c1-16-14-17(8-11-20(16)31)26-25(32-22-6-5-7-23(39-4)35(22)26)28(36)34(13-12-33(2)3)21-15-40(37,38)27-18(21)9-10-19(29)24(27)30/h5-11,14,21H,12-13,15H2,1-4H3/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533246 (CHEMBL4549646) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)[C@@H]3CS(=O)(=O)c4c3ccc(c4Cl)C(F)(F)F)c(-c3ccc(F)c(C)c3)n12 |r| Show InChI InChI=1S/C29H27ClF4N4O4S/c1-16-14-17(8-11-20(16)31)26-25(35-22-6-5-7-23(42-4)38(22)26)28(39)37(13-12-36(2)3)21-15-43(40,41)27-18(21)9-10-19(24(27)30)29(32,33)34/h5-11,14,21H,12-13,15H2,1-4H3/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533246 (CHEMBL4549646) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)[C@@H]3CS(=O)(=O)c4c3ccc(c4Cl)C(F)(F)F)c(-c3ccc(F)c(C)c3)n12 |r| Show InChI InChI=1S/C29H27ClF4N4O4S/c1-16-14-17(8-11-20(16)31)26-25(35-22-6-5-7-23(42-4)38(22)26)28(39)37(13-12-36(2)3)21-15-43(40,41)27-18(21)9-10-19(24(27)30)29(32,33)34/h5-11,14,21H,12-13,15H2,1-4H3/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533249 (CHEMBL4468555) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)[C@@H]3CS(=O)(=O)c4c3ccc(c4C#N)C(F)(F)F)c(-c3ccc(F)c(C)c3)n12 |r| Show InChI InChI=1S/C30H27F4N5O4S/c1-17-14-18(8-11-22(17)31)27-26(36-24-6-5-7-25(43-4)39(24)27)29(40)38(13-12-37(2)3)23-16-44(41,42)28-19(23)9-10-21(20(28)15-35)30(32,33)34/h5-11,14,23H,12-13,16H2,1-4H3/t23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533249 (CHEMBL4468555) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)[C@@H]3CS(=O)(=O)c4c3ccc(c4C#N)C(F)(F)F)c(-c3ccc(F)c(C)c3)n12 |r| Show InChI InChI=1S/C30H27F4N5O4S/c1-17-14-18(8-11-22(17)31)27-26(36-24-6-5-7-25(43-4)39(24)27)29(40)38(13-12-37(2)3)23-16-44(41,42)28-19(23)9-10-21(20(28)15-35)30(32,33)34/h5-11,14,23H,12-13,16H2,1-4H3/t23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533248 (CHEMBL4515745) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)C3CS(=O)(=O)c4c3ccc(Cl)c4Cl)c(-c3ccc(F)c(C)c3)n12 Show InChI InChI=1S/C28H27Cl2FN4O4S/c1-16-14-17(8-11-20(16)31)26-25(32-22-6-5-7-23(39-4)35(22)26)28(36)34(13-12-33(2)3)21-15-40(37,38)27-18(21)9-10-19(29)24(27)30/h5-11,14,21H,12-13,15H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533248 (CHEMBL4515745) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)C3CS(=O)(=O)c4c3ccc(Cl)c4Cl)c(-c3ccc(F)c(C)c3)n12 Show InChI InChI=1S/C28H27Cl2FN4O4S/c1-16-14-17(8-11-20(16)31)26-25(32-22-6-5-7-23(39-4)35(22)26)28(36)34(13-12-33(2)3)21-15-40(37,38)27-18(21)9-10-19(29)24(27)30/h5-11,14,21H,12-13,15H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533245 (CHEMBL4579162) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)C3CSc4c3ccc(Cl)c4Cl)c(-c3ccc(F)c(C)c3)n12 Show InChI InChI=1S/C28H27Cl2FN4O2S/c1-16-14-17(8-11-20(16)31)26-25(32-22-6-5-7-23(37-4)35(22)26)28(36)34(13-12-33(2)3)21-15-38-27-18(21)9-10-19(29)24(27)30/h5-11,14,21H,12-13,15H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533245 (CHEMBL4579162) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)C3CSc4c3ccc(Cl)c4Cl)c(-c3ccc(F)c(C)c3)n12 Show InChI InChI=1S/C28H27Cl2FN4O2S/c1-16-14-17(8-11-20(16)31)26-25(32-22-6-5-7-23(37-4)35(22)26)28(36)34(13-12-33(2)3)21-15-38-27-18(21)9-10-19(29)24(27)30/h5-11,14,21H,12-13,15H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533244 (CHEMBL4466617) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)C3CCc4c3ccc(Cl)c4Cl)c(-c3ccc(F)c(C)c3)n12 Show InChI InChI=1S/C29H29Cl2FN4O2/c1-17-16-18(8-12-22(17)32)28-27(33-24-6-5-7-25(38-4)36(24)28)29(37)35(15-14-34(2)3)23-13-10-20-19(23)9-11-21(30)26(20)31/h5-9,11-12,16,23H,10,13-15H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533244 (CHEMBL4466617) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)C3CCc4c3ccc(Cl)c4Cl)c(-c3ccc(F)c(C)c3)n12 Show InChI InChI=1S/C29H29Cl2FN4O2/c1-17-16-18(8-12-22(17)32)28-27(33-24-6-5-7-25(38-4)36(24)28)29(37)35(15-14-34(2)3)23-13-10-20-19(23)9-11-21(30)26(20)31/h5-9,11-12,16,23H,10,13-15H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533250 (CHEMBL4483703) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)C3CNc4c3ccc(Cl)c4Cl)c(-c3ccc(F)c(C)c3)n12 Show InChI InChI=1S/C28H28Cl2FN5O2/c1-16-14-17(8-11-20(16)31)27-26(33-22-6-5-7-23(38-4)36(22)27)28(37)35(13-12-34(2)3)21-15-32-25-18(21)9-10-19(29)24(25)30/h5-11,14,21,32H,12-13,15H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533250 (CHEMBL4483703) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)C3CNc4c3ccc(Cl)c4Cl)c(-c3ccc(F)c(C)c3)n12 Show InChI InChI=1S/C28H28Cl2FN5O2/c1-16-14-17(8-11-20(16)31)27-26(33-22-6-5-7-23(38-4)36(22)27)28(37)35(13-12-34(2)3)21-15-32-25-18(21)9-10-19(29)24(25)30/h5-11,14,21,32H,12-13,15H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533248 (CHEMBL4515745) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)C3CS(=O)(=O)c4c3ccc(Cl)c4Cl)c(-c3ccc(F)c(C)c3)n12 Show InChI InChI=1S/C28H27Cl2FN4O4S/c1-16-14-17(8-11-20(16)31)26-25(32-22-6-5-7-23(39-4)35(22)26)28(36)34(13-12-33(2)3)21-15-40(37,38)27-18(21)9-10-19(29)24(27)30/h5-11,14,21H,12-13,15H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	79	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of CENP-E in human HeLa cells assessed as HH3 phosphorylated levels after 24 hrs by FACS analysis				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533249 (CHEMBL4468555) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)[C@@H]3CS(=O)(=O)c4c3ccc(c4C#N)C(F)(F)F)c(-c3ccc(F)c(C)c3)n12 |r| Show InChI InChI=1S/C30H27F4N5O4S/c1-17-14-18(8-11-22(17)31)27-26(36-24-6-5-7-25(43-4)39(24)27)29(40)38(13-12-37(2)3)23-16-44(41,42)28-19(23)9-10-21(20(28)15-35)30(32,33)34/h5-11,14,23H,12-13,16H2,1-4H3/t23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of CENP-E in human HeLa cells assessed as HH3 phosphorylated levels after 24 hrs by FACS analysis				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533249 (CHEMBL4468555) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)[C@@H]3CS(=O)(=O)c4c3ccc(c4C#N)C(F)(F)F)c(-c3ccc(F)c(C)c3)n12 |r| Show InChI InChI=1S/C30H27F4N5O4S/c1-17-14-18(8-11-22(17)31)27-26(36-24-6-5-7-25(43-4)39(24)27)29(40)38(13-12-37(2)3)23-16-44(41,42)28-19(23)9-10-21(20(28)15-35)30(32,33)34/h5-11,14,23H,12-13,16H2,1-4H3/t23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of CENP-E in human HeLa cells assessed as HH3 phosphorylated levels after 24 hrs by FACS analysis				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair
Centromere-associated protein E (Homo sapiens (Human))	BDBM50533248 (CHEMBL4515745) Show SMILES COc1cccc2nc(C(=O)N(CCN(C)C)C3CS(=O)(=O)c4c3ccc(Cl)c4Cl)c(-c3ccc(F)c(C)c3)n12 Show InChI InChI=1S/C28H27Cl2FN4O4S/c1-16-14-17(8-11-20(16)31)26-25(32-22-6-5-7-23(39-4)35(22)26)28(36)34(13-12-33(2)3)21-15-40(37,38)27-18(21)9-10-19(29)24(27)30/h5-11,14,21H,12-13,15H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	79	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of CENP-E in human HeLa cells assessed as HH3 phosphorylated levels after 24 hrs by FACS analysis				Bioorg Med Chem Lett 26: 4296-300 (2016) Article DOI: 10.1016/j.bmcl.2016.07.038 BindingDB Entry DOI: 10.7270/Q28P642T
					More data for this Ligand-Target Pair