Compile Data Set for Download or QSAR

Found 84 hits with Last Name = 'hanigan' and Initial = 'tw'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50397360 (CHEMBL2170177 | US10188756, Compound CN110) Show SMILES COc1ccc(Cn2ccc3ccc(cc23)C(=O)NO)cc1 Show InChI InChI=1S/C17H16N2O3/c1-22-15-6-2-12(3-7-15)11-19-9-8-13-4-5-14(10-16(13)19)17(20)18-21/h2-10,21H,11H2,1H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457063 (CHEMBL4209843) Show SMILES ONC(=O)CCCCN1CCc2ccccc2C1c1ccccc1 Show InChI InChI=1S/C20H24N2O2/c23-19(21-24)12-6-7-14-22-15-13-16-8-4-5-11-18(16)20(22)17-9-2-1-3-10-17/h1-5,8-11,20,24H,6-7,12-15H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457052 (CHEMBL4208780) Show SMILES ONC(=O)CCN1CCc2ccccc2C1c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C24H24N2O2/c27-23(25-28)15-17-26-16-14-20-8-4-5-9-22(20)24(26)21-12-10-19(11-13-21)18-6-2-1-3-7-18/h1-13,24,28H,14-17H2,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457055 (CHEMBL4218293) Show SMILES COc1ccc(cc1)C1N(CCC(=O)NO)CCc2ccccc12 Show InChI InChI=1S/C19H22N2O3/c1-24-16-8-6-15(7-9-16)19-17-5-3-2-4-14(17)10-12-21(19)13-11-18(22)20-23/h2-9,19,23H,10-13H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50457048 (CHEMBL4213297) Show SMILES ONC(=O)CCCCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C16H24N2O2/c19-16(17-20)9-3-1-2-6-11-18-12-10-14-7-4-5-8-15(14)13-18/h4-5,7-8,20H,1-3,6,9-13H2,(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC3 (395 to 489 residues)/human NCOR2 expressed in baculovirus infected Sf9 insec...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457048 (CHEMBL4213297) Show SMILES ONC(=O)CCCCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C16H24N2O2/c19-16(17-20)9-3-1-2-6-11-18-12-10-14-7-4-5-8-15(14)13-18/h4-5,7-8,20H,1-3,6,9-13H2,(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457051 (CHEMBL4206571) Show SMILES COc1cccc(c1)C1N(CCC(=O)NO)CCc2ccccc12 Show InChI InChI=1S/C19H22N2O3/c1-24-16-7-4-6-15(13-16)19-17-8-3-2-5-14(17)9-11-21(19)12-10-18(22)20-23/h2-8,13,19,23H,9-12H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457060 (CHEMBL4214404) Show SMILES ONC(=O)CCN1CCc2ccccc2C1c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H19F3N2O2/c20-19(21,22)15-7-5-14(6-8-15)18-16-4-2-1-3-13(16)9-11-24(18)12-10-17(25)23-26/h1-8,18,26H,9-12H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457056 (CHEMBL4218825) Show SMILES CCOc1ccc(cc1)C1N(CCC(=O)NO)CCc2ccccc12 Show InChI InChI=1S/C20H24N2O3/c1-2-25-17-9-7-16(8-10-17)20-18-6-4-3-5-15(18)11-13-22(20)14-12-19(23)21-24/h3-10,20,24H,2,11-14H2,1H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50457048 (CHEMBL4213297) Show SMILES ONC(=O)CCCCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C16H24N2O2/c19-16(17-20)9-3-1-2-6-11-18-12-10-14-7-4-5-8-15(14)13-18/h4-5,7-8,20H,1-3,6,9-13H2,(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-AMC as...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457061 (CHEMBL4213891) Show SMILES ONC(=O)CCN1CCc2ccccc2C1c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H19F3N2O2/c20-19(21,22)15-6-3-5-14(12-15)18-16-7-2-1-4-13(16)8-10-24(18)11-9-17(25)23-26/h1-7,12,18,26H,8-11H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457053 (CHEMBL4208901) Show SMILES ONC(=O)CCCCCCNCc1ccccc1 Show InChI InChI=1S/C14H22N2O2/c17-14(16-18)10-6-1-2-7-11-15-12-13-8-4-3-5-9-13/h3-5,8-9,15,18H,1-2,6-7,10-12H2,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457050 (CHEMBL4206987) Show SMILES ONC(=O)CCN1CCc2ccccc2C1c1cccc2ccccc12 Show InChI InChI=1S/C22H22N2O2/c25-21(23-26)13-15-24-14-12-17-7-2-4-10-19(17)22(24)20-11-5-8-16-6-1-3-9-18(16)20/h1-11,22,26H,12-15H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50457053 (CHEMBL4208901) Show SMILES ONC(=O)CCCCCCNCc1ccccc1 Show InChI InChI=1S/C14H22N2O2/c17-14(16-18)10-6-1-2-7-11-15-12-13-8-4-3-5-9-13/h3-5,8-9,15,18H,1-2,6-7,10-12H2,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC3 (395 to 489 residues)/human NCOR2 expressed in baculovirus infected Sf9 insec...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457059 (CHEMBL4211873) Show SMILES CC(C)(C)c1ccc(cc1)C1N(CCC(=O)NO)CCc2ccccc12 Show InChI InChI=1S/C22H28N2O2/c1-22(2,3)18-10-8-17(9-11-18)21-19-7-5-4-6-16(19)12-14-24(21)15-13-20(25)23-26/h4-11,21,26H,12-15H2,1-3H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457063 (CHEMBL4209843) Show SMILES ONC(=O)CCCCN1CCc2ccccc2C1c1ccccc1 Show InChI InChI=1S/C20H24N2O2/c23-19(21-24)12-6-7-14-22-15-13-16-8-4-5-11-18(16)20(22)17-9-2-1-3-10-17/h1-5,8-11,20,24H,6-7,12-15H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50457063 (CHEMBL4209843) Show SMILES ONC(=O)CCCCN1CCc2ccccc2C1c1ccccc1 Show InChI InChI=1S/C20H24N2O2/c23-19(21-24)12-6-7-14-22-15-13-16-8-4-5-11-18(16)20(22)17-9-2-1-3-10-17/h1-5,8-11,20,24H,6-7,12-15H2,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC3 (395 to 489 residues)/human NCOR2 expressed in baculovirus infected Sf9 insec...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457062 (CHEMBL4210933) Show SMILES ONC(=O)CCN1CCc2ccccc2C1c1ccccc1 Show InChI InChI=1S/C18H20N2O2/c21-17(19-22)11-13-20-12-10-14-6-4-5-9-16(14)18(20)15-7-2-1-3-8-15/h1-9,18,22H,10-13H2,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457047 (CHEMBL4212751) Show SMILES ONC(=O)CCCCCCN(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C21H28N2O2/c24-21(22-25)15-9-1-2-10-16-23(17-19-11-5-3-6-12-19)18-20-13-7-4-8-14-20/h3-8,11-14,25H,1-2,9-10,15-18H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50457047 (CHEMBL4212751) Show SMILES ONC(=O)CCCCCCN(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C21H28N2O2/c24-21(22-25)15-9-1-2-10-16-23(17-19-11-5-3-6-12-19)18-20-13-7-4-8-14-20/h3-8,11-14,25H,1-2,9-10,15-18H2,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC3 (395 to 489 residues)/human NCOR2 expressed in baculovirus infected Sf9 insec...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50457057 (CHEMBL4217705) Show SMILES ONC(=O)CCCCN(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C19H24N2O2/c22-19(20-23)13-7-8-14-21(15-17-9-3-1-4-10-17)16-18-11-5-2-6-12-18/h1-6,9-12,23H,7-8,13-16H2,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC3 (395 to 489 residues)/human NCOR2 expressed in baculovirus infected Sf9 insec...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457054 (CHEMBL4208365) Show SMILES ONC(=O)CCN(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C17H20N2O2/c20-17(18-21)11-12-19(13-15-7-3-1-4-8-15)14-16-9-5-2-6-10-16/h1-10,21H,11-14H2,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457057 (CHEMBL4217705) Show SMILES ONC(=O)CCCCN(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C19H24N2O2/c22-19(20-23)13-7-8-14-21(15-17-9-3-1-4-10-17)16-18-11-5-2-6-12-18/h1-6,9-12,23H,7-8,13-16H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457053 (CHEMBL4208901) Show SMILES ONC(=O)CCCCCCNCc1ccccc1 Show InChI InChI=1S/C14H22N2O2/c17-14(16-18)10-6-1-2-7-11-15-12-13-8-4-3-5-9-13/h3-5,8-9,15,18H,1-2,6-7,10-12H2,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457048 (CHEMBL4213297) Show SMILES ONC(=O)CCCCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C16H24N2O2/c19-16(17-20)9-3-1-2-6-11-18-12-10-14-7-4-5-8-15(14)13-18/h4-5,7-8,20H,1-3,6,9-13H2,(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457057 (CHEMBL4217705) Show SMILES ONC(=O)CCCCN(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C19H24N2O2/c22-19(20-23)13-7-8-14-21(15-17-9-3-1-4-10-17)16-18-11-5-2-6-12-18/h1-6,9-12,23H,7-8,13-16H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457050 (CHEMBL4206987) Show SMILES ONC(=O)CCN1CCc2ccccc2C1c1cccc2ccccc12 Show InChI InChI=1S/C22H22N2O2/c25-21(23-26)13-15-24-14-12-17-7-2-4-10-19(17)22(24)20-11-5-8-16-6-1-3-9-18(16)20/h1-11,22,26H,12-15H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50457047 (CHEMBL4212751) Show SMILES ONC(=O)CCCCCCN(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C21H28N2O2/c24-21(22-25)15-9-1-2-10-16-23(17-19-11-5-3-6-12-19)18-20-13-7-4-8-14-20/h3-8,11-14,25H,1-2,9-10,15-18H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-AMC as...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50457063 (CHEMBL4209843) Show SMILES ONC(=O)CCCCN1CCc2ccccc2C1c1ccccc1 Show InChI InChI=1S/C20H24N2O2/c23-19(21-24)12-6-7-14-22-15-13-16-8-4-5-11-18(16)20(22)17-9-2-1-3-10-17/h1-5,8-11,20,24H,6-7,12-15H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-AMC as...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50457053 (CHEMBL4208901) Show SMILES ONC(=O)CCCCCCNCc1ccccc1 Show InChI InChI=1S/C14H22N2O2/c17-14(16-18)10-6-1-2-7-11-15-12-13-8-4-3-5-9-13/h3-5,8-9,15,18H,1-2,6-7,10-12H2,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-AMC as...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50457050 (CHEMBL4206987) Show SMILES ONC(=O)CCN1CCc2ccccc2C1c1cccc2ccccc12 Show InChI InChI=1S/C22H22N2O2/c25-21(23-26)13-15-24-14-12-17-7-2-4-10-19(17)22(24)20-11-5-8-16-6-1-3-9-18(16)20/h1-11,22,26H,12-15H2,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC3 (395 to 489 residues)/human NCOR2 expressed in baculovirus infected Sf9 insec...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50397360 (CHEMBL2170177 | US10188756, Compound CN110) Show SMILES COc1ccc(Cn2ccc3ccc(cc23)C(=O)NO)cc1 Show InChI InChI=1S/C17H16N2O3/c1-22-15-6-2-12(3-7-15)11-19-9-8-13-4-5-14(10-16(13)19)17(20)18-21/h2-10,21H,11H2,1H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457047 (CHEMBL4212751) Show SMILES ONC(=O)CCCCCCN(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C21H28N2O2/c24-21(22-25)15-9-1-2-10-16-23(17-19-11-5-3-6-12-19)18-20-13-7-4-8-14-20/h3-8,11-14,25H,1-2,9-10,15-18H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457062 (CHEMBL4210933) Show SMILES ONC(=O)CCN1CCc2ccccc2C1c1ccccc1 Show InChI InChI=1S/C18H20N2O2/c21-17(19-22)11-13-20-12-10-14-6-4-5-9-16(14)18(20)15-7-2-1-3-8-15/h1-9,18,22H,10-13H2,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50457057 (CHEMBL4217705) Show SMILES ONC(=O)CCCCN(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C19H24N2O2/c22-19(20-23)13-7-8-14-21(15-17-9-3-1-4-10-17)16-18-11-5-2-6-12-18/h1-6,9-12,23H,7-8,13-16H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-AMC as...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457064 (CHEMBL4209492) Show SMILES ONC(=O)CCN1CCc2ccccc2C1C1CCCCC1 Show InChI InChI=1S/C18H26N2O2/c21-17(19-22)11-13-20-12-10-14-6-4-5-9-16(14)18(20)15-7-2-1-3-8-15/h4-6,9,15,18,22H,1-3,7-8,10-13H2,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50397360 (CHEMBL2170177 | US10188756, Compound CN110) Show SMILES COc1ccc(Cn2ccc3ccc(cc23)C(=O)NO)cc1 Show InChI InChI=1S/C17H16N2O3/c1-22-15-6-2-12(3-7-15)11-19-9-8-13-4-5-14(10-16(13)19)17(20)18-21/h2-10,21H,11H2,1H3,(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC3 (395 to 489 residues)/human NCOR2 expressed in baculovirus infected Sf9 insec...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457052 (CHEMBL4208780) Show SMILES ONC(=O)CCN1CCc2ccccc2C1c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C24H24N2O2/c27-23(25-28)15-17-26-16-14-20-8-4-5-9-22(20)24(26)21-12-10-19(11-13-21)18-6-2-1-3-7-18/h1-13,24,28H,14-17H2,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457066 (CHEMBL4216233) Show SMILES ONC(=O)CCCCNCc1ccccc1 Show InChI InChI=1S/C12H18N2O2/c15-12(14-16)8-4-5-9-13-10-11-6-2-1-3-7-11/h1-3,6-7,13,16H,4-5,8-10H2,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50457062 (CHEMBL4210933) Show SMILES ONC(=O)CCN1CCc2ccccc2C1c1ccccc1 Show InChI InChI=1S/C18H20N2O2/c21-17(19-22)11-13-20-12-10-14-6-4-5-9-16(14)18(20)15-7-2-1-3-8-15/h1-9,18,22H,10-13H2,(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC3 (395 to 489 residues)/human NCOR2 expressed in baculovirus infected Sf9 insec...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457051 (CHEMBL4206571) Show SMILES COc1cccc(c1)C1N(CCC(=O)NO)CCc2ccccc12 Show InChI InChI=1S/C19H22N2O3/c1-24-16-7-4-6-15(13-16)19-17-8-3-2-5-14(17)9-11-21(19)12-10-18(22)20-23/h2-8,13,19,23H,9-12H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50457050 (CHEMBL4206987) Show SMILES ONC(=O)CCN1CCc2ccccc2C1c1cccc2ccccc12 Show InChI InChI=1S/C22H22N2O2/c25-21(23-26)13-15-24-14-12-17-7-2-4-10-19(17)22(24)20-11-5-8-16-6-1-3-9-18(16)20/h1-11,22,26H,12-15H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-AMC as...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457066 (CHEMBL4216233) Show SMILES ONC(=O)CCCCNCc1ccccc1 Show InChI InChI=1S/C12H18N2O2/c15-12(14-16)8-4-5-9-13-10-11-6-2-1-3-7-11/h1-3,6-7,13,16H,4-5,8-10H2,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457060 (CHEMBL4214404) Show SMILES ONC(=O)CCN1CCc2ccccc2C1c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H19F3N2O2/c20-19(21,22)15-7-5-14(6-8-15)18-16-4-2-1-3-13(16)9-11-24(18)12-10-17(25)23-26/h1-8,18,26H,9-12H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457059 (CHEMBL4211873) Show SMILES CC(C)(C)c1ccc(cc1)C1N(CCC(=O)NO)CCc2ccccc12 Show InChI InChI=1S/C22H28N2O2/c1-22(2,3)18-10-8-17(9-11-18)21-19-7-5-4-6-16(19)12-14-24(21)15-13-20(25)23-26/h4-11,21,26H,12-15H2,1-3H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457049 (CHEMBL4206055) Show SMILES ONC(=O)CN1CCc2ccccc2C1c1ccccc1 Show InChI InChI=1S/C17H18N2O2/c20-16(18-21)12-19-11-10-13-6-4-5-9-15(13)17(19)14-7-2-1-3-8-14/h1-9,17,21H,10-12H2,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50457065 (CHEMBL4204967) Show SMILES ONC(=O)CCN1CCc2ccccc2C1 Show InChI InChI=1S/C12H16N2O2/c15-12(13-16)6-8-14-7-5-10-3-1-2-4-11(10)9-14/h1-4,16H,5-9H2,(H,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli using fluor de Lys(R) as substrate pretreated for 5 mins followed by s...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50457066 (CHEMBL4216233) Show SMILES ONC(=O)CCCCNCc1ccccc1 Show InChI InChI=1S/C12H18N2O2/c15-12(14-16)8-4-5-9-13-10-11-6-2-1-3-7-11/h1-3,6-7,13,16H,4-5,8-10H2,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length C-terminal His-tagged HDAC3 (395 to 489 residues)/human NCOR2 expressed in baculovirus infected Sf9 insec...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457056 (CHEMBL4218825) Show SMILES CCOc1ccc(cc1)C1N(CCC(=O)NO)CCc2ccccc12 Show InChI InChI=1S/C20H24N2O3/c1-2-25-17-9-7-16(8-10-17)20-18-6-4-3-5-15(18)11-13-22(20)14-12-19(23)21-24/h3-10,20,24H,2,11-14H2,1H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50457055 (CHEMBL4218293) Show SMILES COc1ccc(cc1)C1N(CCC(=O)NO)CCc2ccccc12 Show InChI InChI=1S/C19H22N2O3/c1-24-16-8-6-15(7-9-16)19-17-5-3-2-4-14(17)10-12-21(19)13-11-18(22)20-23/h2-9,19,23H,10-13H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of recombinant full-length human C-terminal FLAG-His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using Boc-L-Lys(Ac)-A...				ACS Med Chem Lett 8: 824-829 (2017) Article DOI: 10.1021/acsmedchemlett.7b00126 BindingDB Entry DOI: 10.7270/Q2DR2Z42
					More data for this Ligand-Target Pair

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