Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM93132 (PBQ1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West Indies | Assay Description The test compounds were evaluated for their ability to inhibit the catlytic activity of human CYP1 enzymes by means of high throughput fluorometric d... | Org Med Chem Lett 2: 21 (2012) Article DOI: 10.1186/2191-2858-2-21 BindingDB Entry DOI: 10.7270/Q25H7DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM93133 (PBQ2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West Indies | Assay Description The test compounds were evaluated for their ability to inhibit the catlytic activity of human CYP1 enzymes by means of high throughput fluorometric d... | Org Med Chem Lett 2: 21 (2012) Article DOI: 10.1186/2191-2858-2-21 BindingDB Entry DOI: 10.7270/Q25H7DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1B1 (Homo sapiens (Human)) | BDBM93133 (PBQ2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West Indies | Assay Description The test compounds were evaluated for their ability to inhibit the catlytic activity of human CYP1 enzymes by means of high throughput fluorometric d... | Org Med Chem Lett 2: 21 (2012) Article DOI: 10.1186/2191-2858-2-21 BindingDB Entry DOI: 10.7270/Q25H7DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A1 (Homo sapiens (Human)) | BDBM93132 (PBQ1) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West Indies | Assay Description The test compounds were evaluated for their ability to inhibit the catlytic activity of human CYP1 enzymes by means of high throughput fluorometric d... | Org Med Chem Lett 2: 21 (2012) Article DOI: 10.1186/2191-2858-2-21 BindingDB Entry DOI: 10.7270/Q25H7DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A1 (Homo sapiens (Human)) | BDBM93133 (PBQ2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West Indies | Assay Description The test compounds were evaluated for their ability to inhibit the catlytic activity of human CYP1 enzymes by means of high throughput fluorometric d... | Org Med Chem Lett 2: 21 (2012) Article DOI: 10.1186/2191-2858-2-21 BindingDB Entry DOI: 10.7270/Q25H7DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM93132 (PBQ1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West Indies | Assay Description The test compounds were evaluated for their ability to inhibit the catlytic activity of human CYP1 enzymes by means of high throughput fluorometric d... | Org Med Chem Lett 2: 21 (2012) Article DOI: 10.1186/2191-2858-2-21 BindingDB Entry DOI: 10.7270/Q25H7DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1B1 (Homo sapiens (Human)) | BDBM93132 (PBQ1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West Indies | Assay Description The test compounds were evaluated for their ability to inhibit the catlytic activity of human CYP1 enzymes by means of high throughput fluorometric d... | Org Med Chem Lett 2: 21 (2012) Article DOI: 10.1186/2191-2858-2-21 BindingDB Entry DOI: 10.7270/Q25H7DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM93133 (PBQ2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West Indies | Assay Description The test compounds were evaluated for their ability to inhibit the catlytic activity of human CYP1 enzymes by means of high throughput fluorometric d... | Org Med Chem Lett 2: 21 (2012) Article DOI: 10.1186/2191-2858-2-21 BindingDB Entry DOI: 10.7270/Q25H7DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM93132 (PBQ1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West Indies | Assay Description The test compounds were evaluated for their ability to inhibit the catlytic activity of human CYP1 enzymes by means of high throughput fluorometric d... | Org Med Chem Lett 2: 21 (2012) Article DOI: 10.1186/2191-2858-2-21 BindingDB Entry DOI: 10.7270/Q25H7DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM93133 (PBQ2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West Indies | Assay Description The test compounds were evaluated for their ability to inhibit the catlytic activity of human CYP1 enzymes by means of high throughput fluorometric d... | Org Med Chem Lett 2: 21 (2012) Article DOI: 10.1186/2191-2858-2-21 BindingDB Entry DOI: 10.7270/Q25H7DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM93132 (PBQ1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West Indies | Assay Description The test compounds were evaluated for their ability to inhibit the catlytic activity of human CYP1 enzymes by means of high throughput fluorometric d... | Org Med Chem Lett 2: 21 (2012) Article DOI: 10.1186/2191-2858-2-21 BindingDB Entry DOI: 10.7270/Q25H7DWM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM93133 (PBQ2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West Indies | Assay Description The test compounds were evaluated for their ability to inhibit the catlytic activity of human CYP1 enzymes by means of high throughput fluorometric d... | Org Med Chem Lett 2: 21 (2012) Article DOI: 10.1186/2191-2858-2-21 BindingDB Entry DOI: 10.7270/Q25H7DWM | |||||||||||
More data for this Ligand-Target Pair |