Found 52 hits with Last Name = 'zhai' and Initial = 'xy' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM15581
(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50278274
(CHEMBL4166084)Show InChI InChI=1S/C19H20N2O2/c22-19(21-23)11-10-14-6-8-15(9-7-14)13-20-18-12-17(18)16-4-2-1-3-5-16/h1-11,17-18,20,23H,12-13H2,(H,21,22)/b11-10+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50278273
(CHEMBL4173338)Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(CNC2(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C24H31N3O3/c28-22(27-30)10-6-1-2-7-17-25-23(29)20-13-11-19(12-14-20)18-26-24(15-16-24)21-8-4-3-5-9-21/h3-5,8-9,11-14,26,30H,1-2,6-7,10,15-18H2,(H,25,29)(H,27,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged human HDAC1 expressed in baculovirus expression system using Ac-peptide substrate incu... |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged human HDAC1 expressed in baculovirus expression system using Ac-peptide substrate incu... |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50278273
(CHEMBL4173338)Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(CNC2(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C24H31N3O3/c28-22(27-30)10-6-1-2-7-17-25-23(29)20-13-11-19(12-14-20)18-26-24(15-16-24)21-8-4-3-5-9-21/h3-5,8-9,11-14,26,30H,1-2,6-7,10,15-18H2,(H,25,29)(H,27,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of C-terminal His-tagged full length human HDAC2 expressed in baculovirus expression system using Ac-peptide substrate incubated for 15 mi... |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50278274
(CHEMBL4166084)Show InChI InChI=1S/C19H20N2O2/c22-19(21-23)11-10-14-6-8-15(9-7-14)13-20-18-12-17(18)16-4-2-1-3-5-16/h1-11,17-18,20,23H,12-13H2,(H,21,22)/b11-10+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of C-terminal His-tagged full length human HDAC2 expressed in baculovirus expression system using Ac-peptide substrate incubated for 15 mi... |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of C-terminal His-tagged full length human HDAC2 expressed in baculovirus expression system using Ac-peptide substrate incubated for 15 mi... |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM15579
(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50234620
(CHEMBL4099241)Show InChI InChI=1S/C15H13BrN2O3/c16-12-8-14(20)13(19)7-10(12)5-4-9-2-1-3-11(6-9)15(17)18-21/h1-8,19-21H,(H2,17,18)/b5-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 121 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50234626
(CHEMBL4072238)Show InChI InChI=1S/C15H13BrN2O3/c16-12-8-14(20)13(19)7-11(12)6-3-9-1-4-10(5-2-9)15(17)18-21/h1-8,19-21H,(H2,17,18)/b6-3+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50234629
(CHEMBL4089088)Show InChI InChI=1S/C15H13FN2O3/c16-12-8-14(20)13(19)7-10(12)5-4-9-2-1-3-11(6-9)15(17)18-21/h1-8,19-21H,(H2,17,18)/b5-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 193 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50234625
(CHEMBL4093001)Show InChI InChI=1S/C15H13FN2O3/c16-12-8-14(20)13(19)7-11(12)6-3-9-1-4-10(5-2-9)15(17)18-21/h1-8,19-21H,(H2,17,18)/b6-3+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 197 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50234621
(CHEMBL4060903)Show InChI InChI=1S/C15H14N2O2/c16-15(17-19)13-3-1-2-12(10-13)5-4-11-6-8-14(18)9-7-11/h1-10,18-19H,(H2,16,17)/b5-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50278275
(CHEMBL4162637)Show InChI InChI=1S/C23H23N3O/c24-20-8-4-5-9-21(20)26-23(27)18-12-10-16(11-13-18)15-25-22-14-19(22)17-6-2-1-3-7-17/h1-13,19,22,25H,14-15,24H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 218 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Tested in vitro for histamine H3 receptor mediate inhibition of neurogenic contractions in guinea pig isolated ileum assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50234618
(CHEMBL4091505)Show InChI InChI=1S/C15H13FN2O2/c16-13-9-11(6-7-14(13)19)5-4-10-2-1-3-12(8-10)15(17)18-20/h1-9,19-20H,(H2,17,18)/b5-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 246 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50278276
(CHEMBL4176702)Show SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(CNC2CC2c2ccccc2)cc1 Show InChI InChI=1S/C25H25N3O/c26-22-8-4-5-9-23(22)28-25(29)15-14-18-10-12-19(13-11-18)17-27-24-16-21(24)20-6-2-1-3-7-20/h1-15,21,24,27H,16-17,26H2,(H,28,29)/b15-14+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 314 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged human HDAC1 expressed in baculovirus expression system using Ac-peptide substrate incu... |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50234628
(CHEMBL4070601)Show InChI InChI=1S/C15H14N2O3/c16-15(17-20)12-3-1-2-10(8-12)4-5-11-6-7-13(18)14(19)9-11/h1-9,18-20H,(H2,16,17)/b5-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 334 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50234624
(CHEMBL4080291)Show InChI InChI=1S/C15H14N2O2/c16-15(17-19)13-7-3-11(4-8-13)1-2-12-5-9-14(18)10-6-12/h1-10,18-19H,(H2,16,17)/b2-1+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 391 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50278275
(CHEMBL4162637)Show InChI InChI=1S/C23H23N3O/c24-20-8-4-5-9-21(20)26-23(27)18-12-10-16(11-13-18)15-25-22-14-19(22)17-6-2-1-3-7-17/h1-13,19,22,25H,14-15,24H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 413 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50278276
(CHEMBL4176702)Show SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(CNC2CC2c2ccccc2)cc1 Show InChI InChI=1S/C25H25N3O/c26-22-8-4-5-9-23(22)28-25(29)15-14-18-10-12-19(13-11-18)17-27-24-16-21(24)20-6-2-1-3-7-20/h1-15,21,24,27H,16-17,26H2,(H,28,29)/b15-14+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 491 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50234623
(CHEMBL4104513)Show InChI InChI=1S/C15H13FN2O2/c16-13-9-11(5-8-14(13)19)2-1-10-3-6-12(7-4-10)15(17)18-20/h1-9,19-20H,(H2,17,18)/b2-1+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 493 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50234622
(CHEMBL4069570)Show InChI InChI=1S/C15H14N2O3/c16-15(17-20)12-6-3-10(4-7-12)1-2-11-5-8-13(18)14(19)9-11/h1-9,18-20H,(H2,16,17)/b2-1+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 739 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM50446481
(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)Show SMILES FC(F)(F)c1nc(no1)-c1cccc(c1)C(=O)NCC1(CCOCC1)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C25H21F3N4O3S/c26-25(27,28)22-31-20(32-35-22)17-7-4-8-18(13-17)21(33)29-15-24(9-11-34-12-10-24)23-30-19(14-36-23)16-5-2-1-3-6-16/h1-8,13-14H,9-12,15H2,(H,29,33) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50278273
(CHEMBL4173338)Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(CNC2(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C24H31N3O3/c28-22(27-30)10-6-1-2-7-17-25-23(29)20-13-11-19(12-14-20)18-26-24(15-16-24)21-8-4-3-5-9-21/h3-5,8-9,11-14,26,30H,1-2,6-7,10,15-18H2,(H,25,29)(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50278277
(CHEMBL4169910 | US11352322, Compound 28)Show InChI InChI=1S/C17H18N2O2/c20-17(19-21)14-8-6-12(7-9-14)11-18-16-10-15(16)13-4-2-1-3-5-13/h1-9,15-16,18,21H,10-11H2,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50278274
(CHEMBL4166084)Show InChI InChI=1S/C19H20N2O2/c22-19(21-23)11-10-14-6-8-15(9-7-14)13-20-18-12-17(18)16-4-2-1-3-5-16/h1-11,17-18,20,23H,12-13H2,(H,21,22)/b11-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant LSD1 (157 to 852 amino acids) (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red... |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50234619
(CHEMBL4081219)Show InChI InChI=1S/C15H14N2O3/c16-15(17-20)12-3-1-2-10(6-12)4-5-11-7-13(18)9-14(19)8-11/h1-9,18-20H,(H2,16,17)/b5-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50113851
((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM50278274
(CHEMBL4166084)Show InChI InChI=1S/C19H20N2O2/c22-19(21-23)11-10-14-6-8-15(9-7-14)13-20-18-12-17(18)16-4-2-1-3-5-16/h1-11,17-18,20,23H,12-13H2,(H,21,22)/b11-10+ | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50278277
(CHEMBL4169910 | US11352322, Compound 28)Show InChI InChI=1S/C17H18N2O2/c20-17(19-21)14-8-6-12(7-9-14)11-18-16-10-15(16)13-4-2-1-3-5-13/h1-9,15-16,18,21H,10-11H2,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of C-terminal His-tagged full length human HDAC2 expressed in baculovirus expression system using Ac-peptide substrate incubated for 15 mi... |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50234627
(CHEMBL4062570)Show InChI InChI=1S/C14H13N3O/c15-14(17-18)13-3-1-2-12(10-13)5-4-11-6-8-16-9-7-11/h1-10,18H,(H2,15,17)/b5-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50278276
(CHEMBL4176702)Show SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(CNC2CC2c2ccccc2)cc1 Show InChI InChI=1S/C25H25N3O/c26-22-8-4-5-9-23(22)28-25(29)15-14-18-10-12-19(13-11-18)17-27-24-16-21(24)20-6-2-1-3-7-20/h1-15,21,24,27H,16-17,26H2,(H,28,29)/b15-14+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant LSD1 (157 to 852 amino acids) (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red... |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50278277
(CHEMBL4169910 | US11352322, Compound 28)Show InChI InChI=1S/C17H18N2O2/c20-17(19-21)14-8-6-12(7-9-14)11-18-16-10-15(16)13-4-2-1-3-5-13/h1-9,15-16,18,21H,10-11H2,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant LSD1 (157 to 852 amino acids) (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red... |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM50113851
((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50278275
(CHEMBL4162637)Show InChI InChI=1S/C23H23N3O/c24-20-8-4-5-9-21(20)26-23(27)18-12-10-16(11-13-18)15-25-22-14-19(22)17-6-2-1-3-7-17/h1-13,19,22,25H,14-15,24H2,(H,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM23926
((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)Show InChI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM50278273
(CHEMBL4173338)Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(CNC2(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C24H31N3O3/c28-22(27-30)10-6-1-2-7-17-25-23(29)20-13-11-19(12-14-20)18-26-24(15-16-24)21-8-4-3-5-9-21/h3-5,8-9,11-14,26,30H,1-2,6-7,10,15-18H2,(H,25,29)(H,27,28) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM50278273
(CHEMBL4173338)Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(CNC2(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C24H31N3O3/c28-22(27-30)10-6-1-2-7-17-25-23(29)20-13-11-19(12-14-20)18-26-24(15-16-24)21-8-4-3-5-9-21/h3-5,8-9,11-14,26,30H,1-2,6-7,10,15-18H2,(H,25,29)(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50240772
((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/t8-,9+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.63E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 substrate by fluorescence assay |
Eur J Med Chem 126: 246-258 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.035 BindingDB Entry DOI: 10.7270/Q22R3TX0 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50113851
((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)Show InChI InChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM50278276
(CHEMBL4176702)Show SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(CNC2CC2c2ccccc2)cc1 Show InChI InChI=1S/C25H25N3O/c26-22-8-4-5-9-23(22)28-25(29)15-14-18-10-12-19(13-11-18)17-27-24-16-21(24)20-6-2-1-3-7-20/h1-15,21,24,27H,16-17,26H2,(H,28,29)/b15-14+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM50278274
(CHEMBL4166084)Show InChI InChI=1S/C19H20N2O2/c22-19(21-23)11-10-14-6-8-15(9-7-14)13-20-18-12-17(18)16-4-2-1-3-5-16/h1-11,17-18,20,23H,12-13H2,(H,21,22)/b11-10+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM50278277
(CHEMBL4169910 | US11352322, Compound 28)Show InChI InChI=1S/C17H18N2O2/c20-17(19-21)14-8-6-12(7-9-14)11-18-16-10-15(16)13-4-2-1-3-5-13/h1-9,15-16,18,21H,10-11H2,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM50278275
(CHEMBL4162637)Show InChI InChI=1S/C23H23N3O/c24-20-8-4-5-9-21(20)26-23(27)18-12-10-16(11-13-18)15-25-22-14-19(22)17-6-2-1-3-7-17/h1-13,19,22,25H,14-15,24H2,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50278273
(CHEMBL4173338)Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(CNC2(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C24H31N3O3/c28-22(27-30)10-6-1-2-7-17-25-23(29)20-13-11-19(12-14-20)18-26-24(15-16-24)21-8-4-3-5-9-21/h3-5,8-9,11-14,26,30H,1-2,6-7,10,15-18H2,(H,25,29)(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50278276
(CHEMBL4176702)Show SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(CNC2CC2c2ccccc2)cc1 Show InChI InChI=1S/C25H25N3O/c26-22-8-4-5-9-23(22)28-25(29)15-14-18-10-12-19(13-11-18)17-27-24-16-21(24)20-6-2-1-3-7-20/h1-15,21,24,27H,16-17,26H2,(H,28,29)/b15-14+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50278275
(CHEMBL4162637)Show InChI InChI=1S/C23H23N3O/c24-20-8-4-5-9-21(20)26-23(27)18-12-10-16(11-13-18)15-25-22-14-19(22)17-6-2-1-3-7-17/h1-13,19,22,25H,14-15,24H2,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of recombinant LSD1 (157 to 852 amino acids) (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red... |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50278277
(CHEMBL4169910 | US11352322, Compound 28)Show InChI InChI=1S/C17H18N2O2/c20-17(19-21)14-8-6-12(7-9-14)11-18-16-10-15(16)13-4-2-1-3-5-13/h1-9,15-16,18,21H,10-11H2,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM50278274
(CHEMBL4166084)Show InChI InChI=1S/C19H20N2O2/c22-19(21-23)11-10-14-6-8-15(9-7-14)13-20-18-12-17(18)16-4-2-1-3-5-16/h1-11,17-18,20,23H,12-13H2,(H,21,22)/b11-10+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinxiang Medical University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assay |
Eur J Med Chem 140: 392-402 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.038 BindingDB Entry DOI: 10.7270/Q2HH6NK6 |
More data for this Ligand-Target Pair | |