Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50471908 (CHEMBL142016) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
UMR 176 CNRS/Institut Curie Curated by ChEMBL | Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II | J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50471909 (CHEMBL433875) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
UMR 176 CNRS/Institut Curie Curated by ChEMBL | Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II | J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50471908 (CHEMBL142016) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
UMR 176 CNRS/Institut Curie Curated by ChEMBL | Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II | J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50471910 (CHEMBL344226) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
UMR 176 CNRS/Institut Curie Curated by ChEMBL | Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II | J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50471911 (CHEMBL342844) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
UMR 176 CNRS/Institut Curie Curated by ChEMBL | Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II | J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50471916 (CHEMBL140036) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
UMR 176 CNRS/Institut Curie Curated by ChEMBL | Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II | J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50471913 (NK-611) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 5.60E+4 | n/a | n/a | n/a | n/a |
UMR 176 CNRS/Institut Curie Curated by ChEMBL | Assay Description In vitro inhibitory activity against DNA topoisomerase II | J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50471914 (CHEMBL336443) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
UMR 176 CNRS/Institut Curie Curated by ChEMBL | Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II | J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50471909 (CHEMBL433875) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
UMR 176 CNRS/Institut Curie Curated by ChEMBL | Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II | J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50471915 (CHEMBL434650) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
UMR 176 CNRS/Institut Curie Curated by ChEMBL | Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II | J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50127140 ((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 5.60E+4 | n/a | n/a | n/a | n/a |
UMR 176 CNRS/Institut Curie Curated by ChEMBL | Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II | J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human)) | BDBM50471912 (CHEMBL139335) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a |
UMR 176 CNRS/Institut Curie Curated by ChEMBL | Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II | J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB | |||||||||||
More data for this Ligand-Target Pair |