Compile Data Set for Download or QSAR

Found 52 hits with Last Name = 'sun' and Initial = 'ym'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541283 (CHEMBL4638815) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc3[nH]ccc23)c1 Show InChI InChI=1S/C21H16N4O2S/c1-27-14-4-2-3-13(9-14)11-25-12-24-20-17(21(25)26)10-18(28-20)15-5-7-22-19-16(15)6-8-23-19/h2-10,12H,11H2,1H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541281 (CHEMBL4649403) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(N)c2)c1 Show InChI InChI=1S/C19H16N4O2S/c1-25-14-4-2-3-12(7-14)10-23-11-22-18-15(19(23)24)9-16(26-18)13-5-6-21-17(20)8-13/h2-9,11H,10H2,1H3,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541285 (CHEMBL4645138) Show SMILES Fc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc3[nH]ccc23)c1 Show InChI InChI=1S/C20H13FN4OS/c21-13-3-1-2-12(8-13)10-25-11-24-19-16(20(25)26)9-17(27-19)14-4-6-22-18-15(14)5-7-23-18/h1-9,11H,10H2,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541287 (CHEMBL4638636) Show SMILES COc1ccc(Cn2cnc3sc(cc3c2=O)-c2ccnc3[nH]ccc23)cc1 Show InChI InChI=1S/C21H16N4O2S/c1-27-14-4-2-13(3-5-14)11-25-12-24-20-17(21(25)26)10-18(28-20)15-6-8-22-19-16(15)7-9-23-19/h2-10,12H,11H2,1H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541273 (CHEMBL4636499) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccc3[nH]ncc3c2)c1 Show InChI InChI=1S/C21H16N4O2S/c1-27-16-4-2-3-13(7-16)11-25-12-22-20-17(21(25)26)9-19(28-20)14-5-6-18-15(8-14)10-23-24-18/h2-10,12H,11H2,1H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541288 (CHEMBL4648698) Show SMILES COc1ccc(Cn2cnc3sc(cc3c2=O)-c2ccnc3[nH]ccc23)cc1OC Show InChI InChI=1S/C22H18N4O3S/c1-28-17-4-3-13(9-18(17)29-2)11-26-12-25-21-16(22(26)27)10-19(30-21)14-5-7-23-20-15(14)6-8-24-20/h3-10,12H,11H2,1-2H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541283 (CHEMBL4638815) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc3[nH]ccc23)c1 Show InChI InChI=1S/C21H16N4O2S/c1-27-14-4-2-3-13(9-14)11-25-12-24-20-17(21(25)26)10-18(28-20)15-5-7-22-19-16(15)6-8-23-19/h2-10,12H,11H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541289 (CHEMBL4634539) Show SMILES COc1cc(Cn2cnc3sc(cc3c2=O)-c2ccnc3[nH]ccc23)cc(OC)c1 Show InChI InChI=1S/C22H18N4O3S/c1-28-14-7-13(8-15(9-14)29-2)11-26-12-25-21-18(22(26)27)10-19(30-21)16-3-5-23-20-17(16)4-6-24-20/h3-10,12H,11H2,1-2H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541290 (CHEMBL4649693) Show SMILES Nc1cc(ccn1)-c1cc2c(ncn(Cc3cccc(F)c3)c2=O)s1 Show InChI InChI=1S/C18H13FN4OS/c19-13-3-1-2-11(6-13)9-23-10-22-17-14(18(23)24)8-15(25-17)12-4-5-21-16(20)7-12/h1-8,10H,9H2,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541274 (CHEMBL4643315) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccncc2)c1 Show InChI InChI=1S/C19H15N3O2S/c1-24-15-4-2-3-13(9-15)11-22-12-21-18-16(19(22)23)10-17(25-18)14-5-7-20-8-6-14/h2-10,12H,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541286 (CHEMBL4648713) Show SMILES FC(F)(F)c1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc3[nH]ccc23)c1 Show InChI InChI=1S/C21H13F3N4OS/c22-21(23,24)13-3-1-2-12(8-13)10-28-11-27-19-16(20(28)29)9-17(30-19)14-4-6-25-18-15(14)5-7-26-18/h1-9,11H,10H2,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541285 (CHEMBL4645138) Show SMILES Fc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc3[nH]ccc23)c1 Show InChI InChI=1S/C20H13FN4OS/c21-13-3-1-2-12(8-13)10-25-11-24-19-16(20(25)26)9-17(27-19)14-4-6-22-18-15(14)5-7-23-18/h1-9,11H,10H2,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541287 (CHEMBL4638636) Show SMILES COc1ccc(Cn2cnc3sc(cc3c2=O)-c2ccnc3[nH]ccc23)cc1 Show InChI InChI=1S/C21H16N4O2S/c1-27-14-4-2-13(3-5-14)11-25-12-24-20-17(21(25)26)10-18(28-20)15-6-8-22-19-16(15)7-9-23-19/h2-10,12H,11H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541281 (CHEMBL4649403) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(N)c2)c1 Show InChI InChI=1S/C19H16N4O2S/c1-25-14-4-2-3-12(7-14)10-23-11-22-18-15(19(23)24)9-16(26-18)13-5-6-21-17(20)8-13/h2-9,11H,10H2,1H3,(H2,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541273 (CHEMBL4636499) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccc3[nH]ncc3c2)c1 Show InChI InChI=1S/C21H16N4O2S/c1-27-16-4-2-3-13(7-16)11-25-12-22-20-17(21(25)26)9-19(28-20)14-5-6-18-15(8-14)10-23-24-18/h2-10,12H,11H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541291 (CHEMBL4639553) Show SMILES Nc1cc(ccn1)-c1cc2c(ncn(Cc3cccc(c3)C(F)(F)F)c2=O)s1 Show InChI InChI=1S/C19H13F3N4OS/c20-19(21,22)13-3-1-2-11(6-13)9-26-10-25-17-14(18(26)27)8-15(28-17)12-4-5-24-16(23)7-12/h1-8,10H,9H2,(H2,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541288 (CHEMBL4648698) Show SMILES COc1ccc(Cn2cnc3sc(cc3c2=O)-c2ccnc3[nH]ccc23)cc1OC Show InChI InChI=1S/C22H18N4O3S/c1-28-17-4-3-13(9-18(17)29-2)11-26-12-25-21-16(22(26)27)10-19(30-21)14-5-7-23-20-15(14)6-8-24-20/h3-10,12H,11H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541290 (CHEMBL4649693) Show SMILES Nc1cc(ccn1)-c1cc2c(ncn(Cc3cccc(F)c3)c2=O)s1 Show InChI InChI=1S/C18H13FN4OS/c19-13-3-1-2-11(6-13)9-23-10-22-17-14(18(23)24)8-15(25-17)12-4-5-21-16(20)7-12/h1-8,10H,9H2,(H2,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541279 (CHEMBL4644231) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(C)c2)c1 Show InChI InChI=1S/C20H17N3O2S/c1-13-8-15(6-7-21-13)18-10-17-19(26-18)22-12-23(20(17)24)11-14-4-3-5-16(9-14)25-2/h3-10,12H,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541274 (CHEMBL4643315) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccncc2)c1 Show InChI InChI=1S/C19H15N3O2S/c1-24-15-4-2-3-13(9-15)11-22-12-21-18-16(19(22)23)10-17(25-18)14-5-7-20-8-6-14/h2-10,12H,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541292 (CHEMBL4644637) Show SMILES COc1ccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(N)c2)cc1 Show InChI InChI=1S/C19H16N4O2S/c1-25-14-4-2-12(3-5-14)10-23-11-22-18-15(19(23)24)9-16(26-18)13-6-7-21-17(20)8-13/h2-9,11H,10H2,1H3,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541294 (CHEMBL4649876) Show SMILES COc1cc(Cn2cnc3sc(cc3c2=O)-c2ccnc(N)c2)cc(OC)c1 Show InChI InChI=1S/C20H18N4O3S/c1-26-14-5-12(6-15(8-14)27-2)10-24-11-23-19-16(20(24)25)9-17(28-19)13-3-4-22-18(21)7-13/h3-9,11H,10H2,1-2H3,(H2,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541289 (CHEMBL4634539) Show SMILES COc1cc(Cn2cnc3sc(cc3c2=O)-c2ccnc3[nH]ccc23)cc(OC)c1 Show InChI InChI=1S/C22H18N4O3S/c1-28-14-7-13(8-15(9-14)29-2)11-26-12-25-21-18(22(26)27)10-19(30-21)16-3-5-23-20-17(16)4-6-24-20/h3-10,12H,11H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541277 (CHEMBL4649864) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(F)c2)c1 Show InChI InChI=1S/C19H14FN3O2S/c1-25-14-4-2-3-12(7-14)10-23-11-22-18-15(19(23)24)9-16(26-18)13-5-6-21-17(20)8-13/h2-9,11H,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541269 (CHEMBL4641760) Show SMILES COc1cccc(Cn2cnc3cc(ccc3c2=O)-c2ccc3[nH]ncc3c2)c1 Show InChI InChI=1S/C23H18N4O2/c1-29-19-4-2-3-15(9-19)13-27-14-24-22-11-17(5-7-20(22)23(27)28)16-6-8-21-18(10-16)12-25-26-21/h2-12,14H,13H2,1H3,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541271 (CHEMBL4639886) Show SMILES COc1cccc(Cn2ccc3cc(ccc3c2=O)-c2ccc3[nH]ncc3c2)c1 Show InChI InChI=1S/C24H19N3O2/c1-29-21-4-2-3-16(11-21)15-27-10-9-19-12-17(5-7-22(19)24(27)28)18-6-8-23-20(13-18)14-25-26-23/h2-14H,15H2,1H3,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541286 (CHEMBL4648713) Show SMILES FC(F)(F)c1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc3[nH]ccc23)c1 Show InChI InChI=1S/C21H13F3N4OS/c22-21(23,24)13-3-1-2-12(8-13)10-28-11-27-19-16(20(28)29)9-17(30-19)14-4-6-25-18-15(14)5-7-26-18/h1-9,11H,10H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541293 (CHEMBL4637847) Show SMILES COc1ccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(N)c2)cc1OC Show InChI InChI=1S/C20H18N4O3S/c1-26-15-4-3-12(7-16(15)27-2)10-24-11-23-19-14(20(24)25)9-17(28-19)13-5-6-22-18(21)8-13/h3-9,11H,10H2,1-2H3,(H2,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	219	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541270 (CHEMBL4645772) Show SMILES COc1cccc(Cn2ncc3cc(ccc3c2=O)-c2ccc3[nH]ncc3c2)c1 Show InChI InChI=1S/C23H18N4O2/c1-29-20-4-2-3-15(9-20)14-27-23(28)21-7-5-16(10-18(21)13-25-27)17-6-8-22-19(11-17)12-24-26-22/h2-13H,14H2,1H3,(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541291 (CHEMBL4639553) Show SMILES Nc1cc(ccn1)-c1cc2c(ncn(Cc3cccc(c3)C(F)(F)F)c2=O)s1 Show InChI InChI=1S/C19H13F3N4OS/c20-19(21,22)13-3-1-2-11(6-13)9-26-10-25-17-14(18(26)27)8-15(28-17)12-4-5-24-16(23)7-12/h1-8,10H,9H2,(H2,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541278 (CHEMBL4646435) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(Cl)c2)c1 Show InChI InChI=1S/C19H14ClN3O2S/c1-25-14-4-2-3-12(7-14)10-23-11-22-18-15(19(23)24)9-16(26-18)13-5-6-21-17(20)8-13/h2-9,11H,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541284 (CHEMBL4639551) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2cccc3[nH]ccc23)c1 Show InChI InChI=1S/C22H17N3O2S/c1-27-15-5-2-4-14(10-15)12-25-13-24-21-18(22(25)26)11-20(28-21)17-6-3-7-19-16(17)8-9-23-19/h2-11,13,23H,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	583	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541272 (CHEMBL4643620) Show SMILES COc1cccc(CN2CCc3cc(ccc3C2=O)-c2ccc3[nH]ncc3c2)c1 Show InChI InChI=1S/C24H21N3O2/c1-29-21-4-2-3-16(11-21)15-27-10-9-19-12-17(5-7-22(19)24(27)28)18-6-8-23-20(13-18)14-25-26-23/h2-8,11-14H,9-10,15H2,1H3,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	632	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541277 (CHEMBL4649864) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(F)c2)c1 Show InChI InChI=1S/C19H14FN3O2S/c1-25-14-4-2-3-12(7-14)10-23-11-22-18-15(19(23)24)9-16(26-18)13-5-6-21-17(20)8-13/h2-9,11H,10H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541292 (CHEMBL4644637) Show SMILES COc1ccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(N)c2)cc1 Show InChI InChI=1S/C19H16N4O2S/c1-25-14-4-2-12(3-5-14)10-23-11-22-18-15(19(23)24)9-16(26-18)13-6-7-21-17(20)8-13/h2-9,11H,10H2,1H3,(H2,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541271 (CHEMBL4639886) Show SMILES COc1cccc(Cn2ccc3cc(ccc3c2=O)-c2ccc3[nH]ncc3c2)c1 Show InChI InChI=1S/C24H19N3O2/c1-29-21-4-2-3-16(11-21)15-27-10-9-19-12-17(5-7-22(19)24(27)28)18-6-8-23-20(13-18)14-25-26-23/h2-14H,15H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541272 (CHEMBL4643620) Show SMILES COc1cccc(CN2CCc3cc(ccc3C2=O)-c2ccc3[nH]ncc3c2)c1 Show InChI InChI=1S/C24H21N3O2/c1-29-21-4-2-3-16(11-21)15-27-10-9-19-12-17(5-7-22(19)24(27)28)18-6-8-23-20(13-18)14-25-26-23/h2-8,11-14H,9-10,15H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541279 (CHEMBL4644231) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(C)c2)c1 Show InChI InChI=1S/C20H17N3O2S/c1-13-8-15(6-7-21-13)18-10-17-19(26-18)22-12-23(20(17)24)11-14-4-3-5-16(9-14)25-2/h3-10,12H,11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541269 (CHEMBL4641760) Show SMILES COc1cccc(Cn2cnc3cc(ccc3c2=O)-c2ccc3[nH]ncc3c2)c1 Show InChI InChI=1S/C23H18N4O2/c1-29-19-4-2-3-15(9-19)13-27-14-24-22-11-17(5-7-20(22)23(27)28)16-6-8-21-18(10-16)12-25-26-21/h2-12,14H,13H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541275 (CHEMBL4633510) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2cccnc2)c1 Show InChI InChI=1S/C19H15N3O2S/c1-24-15-6-2-4-13(8-15)11-22-12-21-18-16(19(22)23)9-17(25-18)14-5-3-7-20-10-14/h2-10,12H,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541280 (CHEMBL4643565) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(OC)c2)c1 Show InChI InChI=1S/C20H17N3O3S/c1-25-15-5-3-4-13(8-15)11-23-12-22-19-16(20(23)24)10-17(27-19)14-6-7-21-18(9-14)26-2/h3-10,12H,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541282 (CHEMBL4634527) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccc(N)nc2)c1 Show InChI InChI=1S/C19H16N4O2S/c1-25-14-4-2-3-12(7-14)10-23-11-22-18-15(19(23)24)8-16(26-18)13-5-6-17(20)21-9-13/h2-9,11H,10H2,1H3,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50541276 (CHEMBL4635460) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccc(cc2)-c2ccncc2)c1 Show InChI InChI=1S/C25H19N3O2S/c1-30-21-4-2-3-17(13-21)15-28-16-27-24-22(25(28)29)14-23(31-24)20-7-5-18(6-8-20)19-9-11-26-12-10-19/h2-14,16H,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541294 (CHEMBL4649876) Show SMILES COc1cc(Cn2cnc3sc(cc3c2=O)-c2ccnc(N)c2)cc(OC)c1 Show InChI InChI=1S/C20H18N4O3S/c1-26-14-5-12(6-15(8-14)27-2)10-24-11-23-19-16(20(24)25)9-17(28-19)13-3-4-22-18(21)7-13/h3-9,11H,10H2,1-2H3,(H2,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541293 (CHEMBL4637847) Show SMILES COc1ccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(N)c2)cc1OC Show InChI InChI=1S/C20H18N4O3S/c1-26-15-4-3-12(7-16(15)27-2)10-24-11-23-19-14(20(24)25)9-17(28-19)13-5-6-22-18(21)8-13/h3-9,11H,10H2,1-2H3,(H2,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541284 (CHEMBL4639551) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2cccc3[nH]ccc23)c1 Show InChI InChI=1S/C22H17N3O2S/c1-27-15-5-2-4-14(10-15)12-25-13-24-21-18(22(25)26)11-20(28-21)17-6-3-7-19-16(17)8-9-23-19/h2-11,13,23H,12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541282 (CHEMBL4634527) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccc(N)nc2)c1 Show InChI InChI=1S/C19H16N4O2S/c1-25-14-4-2-3-12(7-14)10-23-11-22-18-15(19(23)24)8-16(26-18)13-5-6-17(20)21-9-13/h2-9,11H,10H2,1H3,(H2,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541280 (CHEMBL4643565) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(OC)c2)c1 Show InChI InChI=1S/C20H17N3O3S/c1-25-15-5-3-4-13(8-15)11-23-12-22-19-16(20(23)24)10-17(27-19)14-6-7-21-18(9-14)26-2/h3-10,12H,11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541278 (CHEMBL4646435) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccnc(Cl)c2)c1 Show InChI InChI=1S/C19H14ClN3O2S/c1-25-14-4-2-3-12(7-14)10-23-11-22-18-15(19(23)24)9-16(26-18)13-5-6-21-17(20)8-13/h2-9,11H,10H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50541276 (CHEMBL4635460) Show SMILES COc1cccc(Cn2cnc3sc(cc3c2=O)-c2ccc(cc2)-c2ccncc2)c1 Show InChI InChI=1S/C25H19N3O2S/c1-30-21-4-2-3-17(13-21)15-28-16-27-24-22(25(28)29)14-23(31-24)20-7-5-18(6-8-20)19-9-11-26-12-10-19/h2-14,16H,15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate incubated for 40 mins in presence of [...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126966 BindingDB Entry DOI: 10.7270/Q2N58QX2
					More data for this Ligand-Target Pair

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