Compile Data Set for Download or QSAR

Found 1244 hits with Last Name = 'herrera' and Initial = 'z'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404825 (1-(4-{6-[2-(pyridin-2- yl)acetamido]pyridazin-3-yl...) Show SMILES FC(F)(F)Oc1cccc(CNC(=O)c2cn(CCCCc3ccc(NC(=O)Cc4ccccn4)nn3)nn2)c1 Show InChI InChI=1S/C26H25F3N8O3/c27-26(28,29)40-21-9-5-6-18(14-21)16-31-25(39)22-17-37(36-34-22)13-4-2-7-19-10-11-23(35-33-19)32-24(38)15-20-8-1-3-12-30-20/h1,3,5-6,8-12,14,17H,2,4,7,13,15-16H2,(H,31,39)(H,32,35,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109086 (US10793535, Cmpd ID 727 | US8604016, 670 | US99382...) Show SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccn4)s3)nn2)c1 Show InChI InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-9-5-6-17(14-20)15-22(37)31-21-12-11-18(33-34-21)7-1-2-10-24-35-36-25(40-24)32-23(38)16-19-8-3-4-13-30-19/h3-6,8-9,11-14H,1-2,7,10,15-16H2,(H,31,34,37)(H,32,36,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404911 ((R)-1-(2-fluoro-4-(6-(2-(4-(3- (trifluoromethoxy)p...) Show SMILES CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(ccn3)-c3cccc(OC(F)(F)F)c3)nn2)nn1 |r| Show InChI InChI=1S/C26H24F4N8O3/c1-31-25(40)22-15-38(37-35-22)14-18(27)5-6-19-7-8-23(36-34-19)33-24(39)13-20-11-17(9-10-32-20)16-3-2-4-21(12-16)41-26(28,29)30/h2-4,7-12,15,18H,5-6,13-14H2,1H3,(H,31,40)(H,33,36,39)/t18-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404848 (N-methyl-1-{4-[6-(2-{4-[3- (trifluoromethoxy)pheny...) Show SMILES CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cc(ccn3)-c3cccc(OC(F)(F)F)c3)nn2)nn1 Show InChI InChI=1S/C26H25F3N8O3/c1-30-25(39)22-16-37(36-34-22)12-3-2-6-19-8-9-23(35-33-19)32-24(38)15-20-13-18(10-11-31-20)17-5-4-7-21(14-17)40-26(27,28)29/h4-5,7-11,13-14,16H,2-3,6,12,15H2,1H3,(H,30,39)(H,32,35,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404666 (US10344025, Example 5 | US11370786, Example 5) Show SMILES O=C(Cc1ccccc1)Nc1ccc(CCCCn2cc(nn2)C(=O)NCc2ccccc2)nn1 Show InChI InChI=1S/C26H27N7O2/c34-25(17-20-9-3-1-4-10-20)28-24-15-14-22(29-31-24)13-7-8-16-33-19-23(30-32-33)26(35)27-18-21-11-5-2-6-12-21/h1-6,9-12,14-15,19H,7-8,13,16-18H2,(H,27,35)(H,28,31,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405185 (N-(pyridin-2-ylmethyl)-1-[4-(6-{2-[3- (trifluorome...) Show SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2ccc(CCCCn3cc(nn3)C(=O)NCc3ccccn3)nn2)c1 Show InChI InChI=1S/C26H25F3N8O3/c27-26(28,29)40-21-9-5-6-18(14-21)15-24(38)32-23-11-10-19(33-35-23)7-2-4-13-37-17-22(34-36-37)25(39)31-16-20-8-1-3-12-30-20/h1,3,5-6,8-12,14,17H,2,4,7,13,15-16H2,(H,31,39)(H,32,35,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405183 (N-(cyanomethyl)-1-[4-(6-{2-[3- (trifluoromethoxy)p...) Show SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2ccc(CCCCn3cc(nn3)C(=O)NCC#N)nn2)c1 Show InChI InChI=1S/C22H21F3N8O3/c23-22(24,25)36-17-6-3-4-15(12-17)13-20(34)28-19-8-7-16(29-31-19)5-1-2-11-33-14-18(30-32-33)21(35)27-10-9-26/h3-4,6-8,12,14H,1-2,5,10-11,13H2,(H,27,35)(H,28,31,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50548670 (CHEMBL4741924) Show SMILES CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(OC4CC(F)(F)C4)cc(C)n3)nn2)nn1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GLS1 in human A549 cells assessed as reduction in conversion of glutamine to glutamate measured after 24 hrs				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404924 ((R)-1-(2-fluoro-4-(6-(2-(6-methyl-4- (trifluoromet...) Show SMILES CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(cc(C)n3)C(F)(F)F)nn2)nn1 |r| Show InChI InChI=1S/C21H22F4N8O2/c1-12-7-13(21(23,24)25)8-16(27-12)9-19(34)28-18-6-5-15(29-31-18)4-3-14(22)10-33-11-17(30-32-33)20(35)26-2/h5-8,11,14H,3-4,9-10H2,1-2H3,(H,26,35)(H,28,31,34)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50548671 (CHEMBL4797071) Show SMILES CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cc(OC4CCC4)ccn3)nn2)nn1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405207 (N-(2-methoxyethyl)-1-[4-(6-{2-[3- (trifluoromethox...) Show SMILES COCCNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cccc(OC(F)(F)F)c3)nn2)nn1 Show InChI InChI=1S/C23H26F3N7O4/c1-36-12-10-27-22(35)19-15-33(32-30-19)11-3-2-6-17-8-9-20(31-29-17)28-21(34)14-16-5-4-7-18(13-16)37-23(24,25)26/h4-5,7-9,13,15H,2-3,6,10-12,14H2,1H3,(H,27,35)(H,28,31,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404928 ((R)-1-(4-(6-(2-(4-(3,3- difluorocyclobutoxy)pyridi...) Show SMILES CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(OC4CC(F)(F)C4)ccn3)nn2)nn1 |r| Show InChI InChI=1S/C23H25F3N8O3/c1-27-22(36)19-13-34(33-31-19)12-14(24)2-3-15-4-5-20(32-30-15)29-21(35)9-16-8-17(6-7-28-16)37-18-10-23(25,26)11-18/h4-8,13-14,18H,2-3,9-12H2,1H3,(H,27,36)(H,29,32,35)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50400050 (CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...) Show SMILES O=C(Cc1ccccc1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 Show InChI InChI=1S/C24H24N6O2S3/c31-19(15-17-7-3-1-4-8-17)25-23-29-27-21(34-23)11-13-33-14-12-22-28-30-24(35-22)26-20(32)16-18-9-5-2-6-10-18/h1-10H,11-16H2,(H,25,29,31)(H,26,30,32)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50548670 (CHEMBL4741924) Show SMILES CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(OC4CC(F)(F)C4)cc(C)n3)nn2)nn1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404910 ((R)-1-(2-fluoro-4-(6-(2-(pyridin-2- yl)acetamido)p...) Show SMILES CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3ccccn3)nn2)nn1 |r| Show InChI InChI=1S/C19H21FN8O2/c1-21-19(30)16-12-28(27-25-16)11-13(20)5-6-14-7-8-17(26-24-14)23-18(29)10-15-4-2-3-9-22-15/h2-4,7-9,12-13H,5-6,10-11H2,1H3,(H,21,30)(H,23,26,29)/t13-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404813 (N-methyl-1-[4-(6-{2-[3- (trifluoromethoxy)phenyl]a...) Show SMILES CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cccc(OC(F)(F)F)c3)nn2)nn1 Show InChI InChI=1S/C21H22F3N7O3/c1-25-20(33)17-13-31(30-28-17)10-3-2-6-15-8-9-18(29-27-15)26-19(32)12-14-5-4-7-16(11-14)34-21(22,23)24/h4-5,7-9,11,13H,2-3,6,10,12H2,1H3,(H,25,33)(H,26,29,32)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404866 (N-methyl-1-(4-(6-(2-(4- (trifluoromethyl)pyridin-2...) Show SMILES CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cc(ccn3)C(F)(F)F)nn2)nn1 Show InChI InChI=1S/C20H21F3N8O2/c1-24-19(33)16-12-31(30-28-16)9-3-2-4-14-5-6-17(29-27-14)26-18(32)11-15-10-13(7-8-25-15)20(21,22)23/h5-8,10,12H,2-4,9,11H2,1H3,(H,24,33)(H,26,29,32)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404915 ((R)-1-(2-fluoro-4-(6-(2-(4- (trifluoromethyl)pyrid...) Show SMILES CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(ccn3)C(F)(F)F)nn2)nn1 |r| Show InChI InChI=1S/C20H20F4N8O2/c1-25-19(34)16-11-32(31-29-16)10-13(21)2-3-14-4-5-17(30-28-14)27-18(33)9-15-8-12(6-7-26-15)20(22,23)24/h4-8,11,13H,2-3,9-10H2,1H3,(H,25,34)(H,27,30,33)/t13-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404917 (1-(4-(6-(2-(4-(3,3- difluorocyclobutoxy)pyridin-2-...) Show SMILES CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cc(OC4CC(F)(F)C4)ccn3)nn2)nn1 Show InChI InChI=1S/C23H26F2N8O3/c1-26-22(35)19-14-33(32-30-19)9-3-2-4-15-5-6-20(31-29-15)28-21(34)11-16-10-17(7-8-27-16)36-18-12-23(24,25)13-18/h5-8,10,14,18H,2-4,9,11-13H2,1H3,(H,26,35)(H,28,31,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404881 (N-methyl-1-(4-(6-(2-(4-(2,2,2- trifluoroethoxy)pyr...) Show SMILES CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cc(OCC(F)(F)F)ccn3)nn2)nn1 Show InChI InChI=1S/C21H23F3N8O3/c1-25-20(34)17-12-32(31-29-17)9-3-2-4-14-5-6-18(30-28-14)27-19(33)11-15-10-16(7-8-26-15)35-13-21(22,23)24/h5-8,10,12H,2-4,9,11,13H2,1H3,(H,25,34)(H,27,30,33)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404912 ((S)-1-(2-fluoro-4-(6-(2-(pyridin-2- yl)acetamido)p...) Show SMILES CNC(=O)c1cn(C[C@@H](F)CCc2ccc(NC(=O)Cc3ccccn3)nn2)nn1 |r| Show InChI InChI=1S/C19H21FN8O2/c1-21-19(30)16-12-28(27-25-16)11-13(20)5-6-14-7-8-17(26-24-14)23-18(29)10-15-4-2-3-9-22-15/h2-4,7-9,12-13H,5-6,10-11H2,1H3,(H,21,30)(H,23,26,29)/t13-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405197 (N-methyl-1-(4-{6-[2-(pyridin-3- yl)acetamido]pyrid...) Show SMILES CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cccnc3)nn2)nn1 Show InChI InChI=1S/C19H22N8O2/c1-20-19(29)16-13-27(26-24-16)10-3-2-6-15-7-8-17(25-23-15)22-18(28)11-14-5-4-9-21-12-14/h4-5,7-9,12-13H,2-3,6,10-11H2,1H3,(H,20,29)(H,22,25,28)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM404823 (N-methyl-1-(4-{6-[2-(pyridin-2- yl)acetamido]pyrid...) Show SMILES CNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3ccccn3)nn2)nn1 Show InChI InChI=1S/C19H22N8O2/c1-20-19(29)16-13-27(26-24-16)11-5-3-6-14-8-9-17(25-23-14)22-18(28)12-15-7-2-4-10-21-15/h2,4,7-10,13H,3,5-6,11-12H2,1H3,(H,20,29)(H,22,25,28)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405184 (N-(2-hydroxyethyl)-1-[4-(6-{2-[3- (trifluoromethox...) Show SMILES OCCNC(=O)c1cn(CCCCc2ccc(NC(=O)Cc3cccc(OC(F)(F)F)c3)nn2)nn1 Show InChI InChI=1S/C22H24F3N7O4/c23-22(24,25)36-17-6-3-4-15(12-17)13-20(34)27-19-8-7-16(28-30-19)5-1-2-10-32-14-18(29-31-32)21(35)26-9-11-33/h3-4,6-8,12,14,33H,1-2,5,9-11,13H2,(H,26,35)(H,27,30,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01398 BindingDB Entry DOI: 10.7270/Q25D8WGC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405060 (1-[2-fluoro-4-(4-{2-[2-fluoro-5- (trifluoromethoxy...) Show SMILES FC(CCn1cc(NC(=O)Cc2cc(OC(F)(F)F)ccc2F)nn1)Cn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F Show InChI InChI=1S/C26H21F9N8O4/c27-16(11-43-12-21(38-40-43)24(45)36-10-15-8-18(2-4-20(15)29)47-26(33,34)35)5-6-42-13-22(39-41-42)37-23(44)9-14-7-17(1-3-19(14)28)46-25(30,31)32/h1-4,7-8,12-13,16H,5-6,9-11H2,(H,36,45)(H,37,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405061 (1-(2-fluoro-4-{4-[2-(6-methylpyridin- 3-yl)acetami...) Show SMILES Cc1ccc(CC(=O)Nc2cn(CCC(F)Cn3cc(nn3)C(=O)NCc3cc(OC(F)(F)F)ccc3F)nn2)cn1 Show InChI InChI=1S/C25H24F5N9O3/c1-15-2-3-16(10-31-15)8-23(40)33-22-14-38(37-35-22)7-6-18(26)12-39-13-21(34-36-39)24(41)32-11-17-9-19(4-5-20(17)27)42-25(28,29)30/h2-5,9-10,13-14,18H,6-8,11-12H2,1H3,(H,32,41)(H,33,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405062 (1-[2-fluoro-4-(4-{2-[3- (trifluoromethoxy)phenyl]a...) Show SMILES FC(CCn1cc(NC(=O)Cc2cccc(OC(F)(F)F)c2)nn1)Cn1cc(nn1)C(=O)NCc1ncccc1F Show InChI InChI=1S/C24H22F5N9O3/c25-16(12-38-13-20(33-35-38)23(40)31-11-19-18(26)5-2-7-30-19)6-8-37-14-21(34-36-37)32-22(39)10-15-3-1-4-17(9-15)41-24(27,28)29/h1-5,7,9,13-14,16H,6,8,10-12H2,(H,31,40)(H,32,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405063 (1-[2-fluoro-4-(4-{2-[3- (trifluoromethoxy)phenyl]a...) Show SMILES FC(CCn1cc(NC(=O)Cc2cccc(OC(F)(F)F)c2)nn1)Cn1cc(nn1)C(=O)NCc1cc(ccn1)C(F)(F)F Show InChI InChI=1S/C25H22F7N9O3/c26-17(12-41-13-20(36-38-41)23(43)34-11-18-10-16(4-6-33-18)24(27,28)29)5-7-40-14-21(37-39-40)35-22(42)9-15-2-1-3-19(8-15)44-25(30,31)32/h1-4,6,8,10,13-14,17H,5,7,9,11-12H2,(H,34,43)(H,35,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405064 (1-[2-fluoro-4-(4-{2-[3- (trifluoromethoxy)phenyl]a...) Show SMILES FC(CCn1cc(NC(=O)Cc2cccc(OC(F)(F)F)c2)nn1)Cn1cc(nn1)C(=O)NCc1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C26H23F7N8O4/c27-18(13-41-14-21(36-38-41)24(43)34-12-17-4-2-6-20(10-17)45-26(31,32)33)7-8-40-15-22(37-39-40)35-23(42)11-16-3-1-5-19(9-16)44-25(28,29)30/h1-6,9-10,14-15,18H,7-8,11-13H2,(H,34,43)(H,35,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405067 (1-[3-fluoro-4-(4-{2-[3- (trifluoromethoxy)phenyl]a...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1ccc(nc1)C(F)(F)F)Cn1cc(NC(=O)Cc2cccc(OC(F)(F)F)c2)nn1 Show InChI InChI=1S/C25H22F7N9O3/c26-17(6-7-40-13-19(36-38-40)23(43)34-11-16-4-5-20(33-10-16)24(27,28)29)12-41-14-21(37-39-41)35-22(42)9-15-2-1-3-18(8-15)44-25(30,31)32/h1-5,8,10,13-14,17H,6-7,9,11-12H2,(H,34,43)(H,35,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405068 (1-[3-fluoro-4-(4-{2-[2-fluoro-5- (trifluoromethoxy...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1ccc(nc1)C(F)(F)F)Cn1cc(NC(=O)Cc2cc(OC(F)(F)F)ccc2F)nn1 Show InChI InChI=1S/C25H21F8N9O3/c26-16(5-6-41-12-19(37-39-41)23(44)35-10-14-1-4-20(34-9-14)24(28,29)30)11-42-13-21(38-40-42)36-22(43)8-15-7-17(2-3-18(15)27)45-25(31,32)33/h1-4,7,9,12-13,16H,5-6,8,10-11H2,(H,35,44)(H,36,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405069 (1-[4-(4-{2-[2-fluoro-5- (trifluoromethoxy)phenyl]a...) Show SMILES FC(CCn1cc(NC(=O)Cc2cc(OC(F)(F)F)ccc2F)nn1)Cn1cc(nn1)C(=O)NCc1cc(ccn1)C(F)(F)F Show InChI InChI=1S/C25H21F8N9O3/c26-16(11-42-12-20(37-39-42)23(44)35-10-17-9-15(3-5-34-17)24(28,29)30)4-6-41-13-21(38-40-41)36-22(43)8-14-7-18(1-2-19(14)27)45-25(31,32)33/h1-3,5,7,9,12-13,16H,4,6,8,10-11H2,(H,35,44)(H,36,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405070 (1-[4-(4-{2-[3- (trifluoromethoxy)phenyl]acetamido}...) Show SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2cn(CCCCn3cc(nn3)C(=O)NCc3cc(ccn3)C(F)(F)F)nn2)c1 Show InChI InChI=1S/C25H23F6N9O3/c26-24(27,28)17-6-7-32-18(12-17)13-33-23(42)20-14-39(37-35-20)8-1-2-9-40-15-21(36-38-40)34-22(41)11-16-4-3-5-19(10-16)43-25(29,30)31/h3-7,10,12,14-15H,1-2,8-9,11,13H2,(H,33,42)(H,34,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405071 (1-(4-{4-[2-(5-chloro-2- fluorophenyl)acetamido]-1H...) Show SMILES Fc1ccc(Cl)cc1CNC(=O)c1cn(CCCCn2cc(NC(=O)Cc3cc(Cl)ccc3F)nn2)nn1 Show InChI InChI=1S/C24H22Cl2F2N8O2/c25-17-3-5-19(27)15(9-17)11-23(37)30-22-14-36(34-32-22)8-2-1-7-35-13-21(31-33-35)24(38)29-12-16-10-18(26)4-6-20(16)28/h3-6,9-10,13-14H,1-2,7-8,11-12H2,(H,29,38)(H,30,37)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405072 (1-[2-fluoro-4-(4-{2-[2-fluoro-5- (trifluoromethoxy...) Show SMILES FC(CCn1cc(NC(=O)Cc2cc(OC(F)(F)F)ccc2F)nn1)Cn1cc(nn1)C(=O)NCc1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C26H22F8N8O4/c27-17(12-42-13-21(37-39-42)24(44)35-11-15-2-1-3-18(8-15)45-25(29,30)31)6-7-41-14-22(38-40-41)36-23(43)10-16-9-19(4-5-20(16)28)46-26(32,33)34/h1-5,8-9,13-14,17H,6-7,10-12H2,(H,35,44)(H,36,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405073 (1-[2-fluoro-4-(4-{2-[2-fluoro-5- (trifluoromethoxy...) Show SMILES FC(CCn1cc(NC(=O)Cc2cc(OC(F)(F)F)ccc2F)nn1)Cn1cc(nn1)C(=O)NCc1ncccc1F Show InChI InChI=1S/C24H21F6N9O3/c25-15(11-39-12-20(34-36-39)23(41)32-10-19-18(27)2-1-6-31-19)5-7-38-13-21(35-37-38)33-22(40)9-14-8-16(3-4-17(14)26)42-24(28,29)30/h1-4,6,8,12-13,15H,5,7,9-11H2,(H,32,41)(H,33,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405069 (1-[4-(4-{2-[2-fluoro-5- (trifluoromethoxy)phenyl]a...) Show SMILES FC(CCn1cc(NC(=O)Cc2cc(OC(F)(F)F)ccc2F)nn1)Cn1cc(nn1)C(=O)NCc1cc(ccn1)C(F)(F)F Show InChI InChI=1S/C25H21F8N9O3/c26-16(11-42-12-20(37-39-42)23(44)35-10-17-9-15(3-5-34-17)24(28,29)30)4-6-41-13-21(38-40-41)36-22(43)8-14-7-18(1-2-19(14)27)45-25(31,32)33/h1-3,5,7,9,12-13,16H,4,6,8,10-11H2,(H,35,44)(H,36,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405075 (1-(2-fluoro-4-{4-[2-(pyridin-2- yl)acetamido]-1H-1...) Show SMILES FC(CCn1cc(NC(=O)Cc2ccccn2)nn1)Cn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F Show InChI InChI=1S/C24H22F5N9O3/c25-16(6-8-37-14-21(34-36-37)32-22(39)10-17-3-1-2-7-30-17)12-38-13-20(33-35-38)23(40)31-11-15-9-18(4-5-19(15)26)41-24(27,28)29/h1-5,7,9,13-14,16H,6,8,10-12H2,(H,31,40)(H,32,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405076 (5-[3-fluoro-4-(4-{[(6-methylpyridin- 3-yl)methyl]c...) Show SMILES Cc1ccc(CNC(=O)c2cn(CC(F)CCc3nnc(s3)C(=O)NCc3cccc(OC(F)(F)F)c3)nn2)cn1 Show InChI InChI=1S/C25H24F4N8O3S/c1-15-5-6-17(11-30-15)12-31-22(38)20-14-37(36-33-20)13-18(26)7-8-21-34-35-24(41-21)23(39)32-10-16-3-2-4-19(9-16)40-25(27,28)29/h2-6,9,11,14,18H,7-8,10,12-13H2,1H3,(H,31,38)(H,32,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405077 (1-{2-fluoro-4-[4-({[6- (trifluoromethyl)pyridin-3-...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1ccc(nc1)C(F)(F)F)Cn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F Show InChI InChI=1S/C25H21F8N9O3/c26-16(5-6-41-12-19(37-39-41)22(43)35-9-14-1-4-21(34-8-14)24(28,29)30)11-42-13-20(38-40-42)23(44)36-10-15-7-17(2-3-18(15)27)45-25(31,32)33/h1-4,7-8,12-13,16H,5-6,9-11H2,(H,35,43)(H,36,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405078 (1-{2-fluoro-4-[4-({[6- (trifluoromethyl)pyridin-2-...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1cccc(n1)C(F)(F)F)Cn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F Show InChI InChI=1S/C25H21F8N9O3/c26-15(6-7-41-12-19(37-39-41)23(44)35-10-16-2-1-3-21(36-16)24(28,29)30)11-42-13-20(38-40-42)22(43)34-9-14-8-17(4-5-18(14)27)45-25(31,32)33/h1-5,8,12-13,15H,6-7,9-11H2,(H,34,43)(H,35,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405079 (1-{2-fluoro-4-[4-({[2-fluoro-5- (trifluoromethoxy)...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F)Cn1cc(nn1)C(=O)NCc1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C25H21F8N9O3/c26-16(11-42-13-21(38-40-42)23(44)36-10-17-2-1-15(9-34-17)24(28,29)30)5-6-41-12-20(37-39-41)22(43)35-8-14-7-18(3-4-19(14)27)45-25(31,32)33/h1-4,7,9,12-13,16H,5-6,8,10-11H2,(H,35,43)(H,36,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405080 (1-{2-fluoro-4-[4-({[2-fluoro-5- (trifluoromethoxy)...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F)Cn1cc(nn1)C(=O)NCc1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C25H21F8N9O3/c26-16(11-42-13-20(38-40-42)22(43)35-9-14-1-4-21(34-8-14)24(28,29)30)5-6-41-12-19(37-39-41)23(44)36-10-15-7-17(2-3-18(15)27)45-25(31,32)33/h1-4,7-8,12-13,16H,5-6,9-11H2,(H,35,43)(H,36,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405081 (1-{2-fluoro-4-[4-({[2-fluoro-5- (trifluoromethoxy)...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F)Cn1cc(nn1)C(=O)NCc1cccc(n1)C(F)(F)F Show InChI InChI=1S/C25H21F8N9O3/c26-15(11-42-13-20(38-40-42)23(44)35-10-16-2-1-3-21(36-16)24(28,29)30)6-7-41-12-19(37-39-41)22(43)34-9-14-8-17(4-5-18(14)27)45-25(31,32)33/h1-5,8,12-13,15H,6-7,9-11H2,(H,34,43)(H,35,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405082 (1-{2-fluoro-4-[4-({[2-fluoro-5- (trifluoromethoxy)...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F)Cn1cc(nn1)C(=O)NCc1cc(ccn1)C(F)(F)F Show InChI InChI=1S/C25H21F8N9O3/c26-16(11-42-13-21(38-40-42)23(44)36-10-17-8-15(3-5-34-17)24(28,29)30)4-6-41-12-20(37-39-41)22(43)35-9-14-7-18(1-2-19(14)27)45-25(31,32)33/h1-3,5,7-8,12-13,16H,4,6,9-11H2,(H,35,43)(H,36,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405083 (1-{2-fluoro-4-[4-({[2-fluoro-5- (trifluoromethoxy)...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F)Cn1cc(nn1)C(=O)NCc1ncccc1F Show InChI InChI=1S/C24H21F6N9O3/c25-15(11-39-13-21(35-37-39)23(41)33-10-19-18(27)2-1-6-31-19)5-7-38-12-20(34-36-38)22(40)32-9-14-8-16(3-4-17(14)26)42-24(28,29)30/h1-4,6,8,12-13,15H,5,7,9-11H2,(H,32,40)(H,33,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405084 (1-{2-fluoro-4-[4-({[3- (trifluoromethoxy)phenyl]me...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1cccc(OC(F)(F)F)c1)Cn1cc(nn1)C(=O)NCc1cc(ccn1)C(F)(F)F Show InChI InChI=1S/C25H22F7N9O3/c26-17(12-41-14-21(37-39-41)23(43)35-11-18-9-16(4-6-33-18)24(27,28)29)5-7-40-13-20(36-38-40)22(42)34-10-15-2-1-3-19(8-15)44-25(30,31)32/h1-4,6,8-9,13-14,17H,5,7,10-12H2,(H,34,42)(H,35,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405085 (1-{2-fluoro-4-[4-({[3- (trifluoromethoxy)phenyl]me...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1cccc(OC(F)(F)F)c1)Cn1cc(nn1)C(=O)NCc1ncccc1F Show InChI InChI=1S/C24H22F5N9O3/c25-16(12-38-14-21(34-36-38)23(40)32-11-19-18(26)5-2-7-30-19)6-8-37-13-20(33-35-37)22(39)31-10-15-3-1-4-17(9-15)41-24(27,28)29/h1-5,7,9,13-14,16H,6,8,10-12H2,(H,31,39)(H,32,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405086 (1-{2-fluoro-4-[4-({[3- (trifluoromethoxy)phenyl]me...) Show SMILES Cc1ccc(CNC(=O)c2cn(CC(F)CCn3cc(nn3)C(=O)NCc3cccc(OC(F)(F)F)c3)nn2)cn1 Show InChI InChI=1S/C25H25F4N9O3/c1-16-5-6-18(11-30-16)12-32-24(40)22-15-38(36-34-22)13-19(26)7-8-37-14-21(33-35-37)23(39)31-10-17-3-2-4-20(9-17)41-25(27,28)29/h2-6,9,11,14-15,19H,7-8,10,12-13H2,1H3,(H,31,39)(H,32,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405087 (1-{2-fluoro-4-[4-({[3- (trifluoromethoxy)phenyl]me...) Show SMILES FC(CCn1cc(nn1)C(=O)NCc1cccc(OC(F)(F)F)c1)Cn1cc(nn1)C(=O)NCc1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C25H22F7N9O3/c26-17(12-41-14-21(37-39-41)23(43)35-11-18-5-4-16(10-33-18)24(27,28)29)6-7-40-13-20(36-38-40)22(42)34-9-15-2-1-3-19(8-15)44-25(30,31)32/h1-5,8,10,13-14,17H,6-7,9,11-12H2,(H,34,42)(H,35,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 1244 total )  |  Next  |  Last  >>

Jump to: