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Compile Data Set for Download or QSAR

Found 6 hits with Last Name = 'abdul rahman' and Initial = 'mb'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50320314
PNG
(5-(Naphthalen-1-ylmethyl)-3-(piperazin-1-ylmethyl)...)
Show SMILES S=c1oc(Cc2cccc3ccccc23)nn1CN1CCNCC1
Show InChI InChI=1S/C18H20N4OS/c24-18-22(13-21-10-8-19-9-11-21)20-17(23-18)12-15-6-3-5-14-4-1-2-7-16(14)15/h1-7,19H,8-13H2
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n/an/a 870n/an/an/an/an/an/a



University Putra Malaysia

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 mins


Bioorg Med Chem Lett 20: 3755-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.067
BindingDB Entry DOI: 10.7270/Q290240T
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50320310
PNG
(1-ylmethyl)-3-(piperidin-1-ylmethyl)-1,3,4-oxadiaz...)
Show SMILES S=c1oc(Cc2cccc3ccccc23)nn1CN1CCCCC1
Show InChI InChI=1S/C19H21N3OS/c24-19-22(14-21-11-4-1-5-12-21)20-18(23-19)13-16-9-6-8-15-7-2-3-10-17(15)16/h2-3,6-10H,1,4-5,11-14H2
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PubMed
n/an/a 970n/an/an/an/an/an/a



University Putra Malaysia

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 mins


Bioorg Med Chem Lett 20: 3755-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.067
BindingDB Entry DOI: 10.7270/Q290240T
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50320312
PNG
((Naphthalen-1-ylmethyl)-3-(pyrrolidin-1-ylmethyl)-...)
Show SMILES S=c1oc(Cc2cccc3ccccc23)nn1CN1CCCC1
Show InChI InChI=1S/C18H19N3OS/c23-18-21(13-20-10-3-4-11-20)19-17(22-18)12-15-8-5-7-14-6-1-2-9-16(14)15/h1-2,5-9H,3-4,10-13H2
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n/an/a 1.33E+3n/an/an/an/an/an/a



University Putra Malaysia

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 mins


Bioorg Med Chem Lett 20: 3755-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.067
BindingDB Entry DOI: 10.7270/Q290240T
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50320311
PNG
((Morpholinomethyl)-5-(naphthalen-1-ylmethyl)-1,3,4...)
Show SMILES S=c1oc(Cc2cccc3ccccc23)nn1CN1CCOCC1
Show InChI InChI=1S/C18H19N3O2S/c24-18-21(13-20-8-10-22-11-9-20)19-17(23-18)12-15-6-3-5-14-4-1-2-7-16(14)15/h1-7H,8-13H2
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n/an/a 1.34E+3n/an/an/an/an/an/a



University Putra Malaysia

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 mins


Bioorg Med Chem Lett 20: 3755-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.067
BindingDB Entry DOI: 10.7270/Q290240T
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50320313
PNG
(3-((4-Methylpiperazin-1-yl)methyl)-5-(naphthalen-1...)
Show SMILES CN1CCN(Cn2nc(Cc3cccc4ccccc34)oc2=S)CC1
Show InChI InChI=1S/C19H22N4OS/c1-21-9-11-22(12-10-21)14-23-19(25)24-18(20-23)13-16-7-4-6-15-5-2-3-8-17(15)16/h2-8H,9-14H2,1H3
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Article
PubMed
n/an/a 1.49E+3n/an/an/an/an/an/a



University Putra Malaysia

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 mins


Bioorg Med Chem Lett 20: 3755-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.067
BindingDB Entry DOI: 10.7270/Q290240T
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50031467
PNG
(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Show SMILES OCc1cc(=O)c(O)co1
Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
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KEGG
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Article
PubMed
n/an/a 9.18E+3n/an/an/an/an/an/a



University Putra Malaysia

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 mins


Bioorg Med Chem Lett 20: 3755-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.067
BindingDB Entry DOI: 10.7270/Q290240T
More data for this
Ligand-Target Pair