Found 36 hits with Last Name = 'agersø' and Initial = 'h' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087749
(CHEMBL261911 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C173H270N46O49/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-55-130(228)199-117(170(267)268)61-65-129(227)183-68-41-40-51-112(154(251)208-121(74-101-45-33-31-34-46-101)159(256)218-140(94(11)19-2)167(264)196-98(15)146(243)205-123(77-104-80-187-109-50-39-38-49-107(104)109)157(254)207-119(73-91(5)6)158(255)216-138(92(7)8)165(262)204-111(53-43-70-185-172(178)179)149(246)188-82-131(229)197-110(52-42-69-184-171(176)177)148(245)191-85-137(238)239)202-153(250)113(54-44-71-186-173(180)181)200-144(241)96(13)193-143(240)95(12)195-152(249)116(60-64-128(175)226)198-132(230)83-189-151(248)115(63-67-135(234)235)203-155(252)118(72-90(3)4)206-156(253)120(76-103-56-58-106(225)59-57-103)209-162(259)125(86-220)212-164(261)127(88-222)213-166(263)139(93(9)10)217-161(258)124(79-136(236)237)210-163(260)126(87-221)214-169(266)142(100(17)224)219-160(257)122(75-102-47-35-32-36-48-102)211-168(265)141(99(16)223)215-133(231)84-190-150(247)114(62-66-134(232)233)201-145(242)97(14)194-147(244)108(174)78-105-81-182-89-192-105/h31-36,38-39,45-50,56-59,80-81,89-100,108,110-127,138-142,187,220-225H,18-30,37,40-44,51-55,60-79,82-88,174H2,1-17H3,(H2,175,226)(H,182,192)(H,183,227)(H,188,246)(H,189,248)(H,190,247)(H,191,245)(H,193,240)(H,194,244)(H,195,249)(H,196,264)(H,197,229)(H,198,230)(H,199,228)(H,200,241)(H,201,242)(H,202,250)(H,203,252)(H,204,262)(H,205,243)(H,206,253)(H,207,254)(H,208,251)(H,209,259)(H,210,260)(H,211,265)(H,212,261)(H,213,263)(H,214,266)(H,215,231)(H,216,255)(H,217,258)(H,218,256)(H,219,257)(H,232,233)(H,234,235)(H,236,237)(H,238,239)(H,267,268)(H4,176,177,184)(H4,178,179,185)(H4,180,181,186)/t94-,95-,96-,97-,98-,99+,100+,108-,110-,111-,112-,113-,114-,115-,116-,117?,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,138-,139-,140-,141-,142-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0360 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087750
(CHEMBL409300 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCNC(=O)CCC(NC(=O)CCCCCCCCCCCCC)C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C189H294N42O55/c1-19-22-24-26-28-30-32-34-36-38-46-64-145(241)210-130(187(283)284)71-77-143(239)195-82-52-50-61-124(166(262)199-95-147(243)208-123(63-54-84-197-189(192)193)165(261)202-98-154(254)255)216-182(278)155(105(8)9)228-175(271)133(86-104(6)7)219-174(270)137(90-117-93-198-122-60-49-48-59-120(117)122)217-163(259)111(16)207-184(280)157(107(12)21-3)230-176(272)135(87-114-55-42-40-43-56-114)220-171(267)129(75-81-152(250)251)215-170(266)125(62-51-53-83-196-144(240)78-72-131(188(285)286)211-146(242)65-47-39-37-35-33-31-29-27-25-23-20-2)212-161(257)109(14)204-160(256)108(13)206-169(265)128(70-76-142(191)238)209-148(244)96-200-168(264)127(74-80-151(248)249)214-172(268)132(85-103(4)5)218-173(269)134(89-116-66-68-119(237)69-67-116)221-179(275)139(99-232)224-181(277)141(101-234)225-183(279)156(106(10)11)229-178(274)138(92-153(252)253)222-180(276)140(100-233)226-186(282)159(113(18)236)231-177(273)136(88-115-57-44-41-45-58-115)223-185(281)158(112(17)235)227-149(245)97-201-167(263)126(73-79-150(246)247)213-162(258)110(15)205-164(260)121(190)91-118-94-194-102-203-118/h40-45,48-49,55-60,66-69,93-94,102-113,121,123-141,155-159,198,232-237H,19-39,46-47,50-54,61-65,70-92,95-101,190H2,1-18H3,(H2,191,238)(H,194,203)(H,195,239)(H,196,240)(H,199,262)(H,200,264)(H,201,263)(H,202,261)(H,204,256)(H,205,260)(H,206,265)(H,207,280)(H,208,243)(H,209,244)(H,210,241)(H,211,242)(H,212,257)(H,213,258)(H,214,268)(H,215,266)(H,216,278)(H,217,259)(H,218,269)(H,219,270)(H,220,267)(H,221,275)(H,222,276)(H,223,281)(H,224,277)(H,225,279)(H,226,282)(H,227,245)(H,228,271)(H,229,274)(H,230,272)(H,231,273)(H,246,247)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H,283,284)(H,285,286)(H4,192,193,197)/t107-,108-,109-,110-,111-,112+,113+,121-,123-,124-,125-,126-,127-,128-,129-,130?,131?,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,155-,156-,157-,158-,159-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.05 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087758
(CHEMBL409270 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(O)=O)C(O)=O Show InChI InChI=1S/C181H281N47O54/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-55-135(237)206-122(178(281)282)61-67-134(236)191-72-41-40-51-121(177(279)280)213-160(262)119(64-70-141(245)246)210-158(260)114(53-43-74-193-180(186)187)204-136(238)86-196-154(256)113(52-42-73-192-179(184)185)212-172(274)144(95(7)8)225-165(267)124(77-94(5)6)216-164(266)128(81-107-84-195-112-50-39-38-49-110(107)112)214-152(254)101(15)203-174(276)146(97(11)19-2)227-166(268)126(78-104-45-33-31-34-46-104)217-161(263)120(65-71-142(247)248)211-159(261)115(54-44-75-194-181(188)189)207-150(252)99(13)200-149(251)98(12)202-157(259)118(60-66-133(183)235)205-137(239)87-197-156(258)117(63-69-140(243)244)209-162(264)123(76-93(3)4)215-163(265)125(80-106-56-58-109(234)59-57-106)218-169(271)130(89-229)221-171(273)132(91-231)222-173(275)145(96(9)10)226-168(270)129(83-143(249)250)219-170(272)131(90-230)223-176(278)148(103(17)233)228-167(269)127(79-105-47-35-32-36-48-105)220-175(277)147(102(16)232)224-138(240)88-198-155(257)116(62-68-139(241)242)208-151(253)100(14)201-153(255)111(182)82-108-85-190-92-199-108/h31-36,38-39,45-50,56-59,84-85,92-103,111,113-132,144-148,195,229-234H,18-30,37,40-44,51-55,60-83,86-91,182H2,1-17H3,(H2,183,235)(H,190,199)(H,191,236)(H,196,256)(H,197,258)(H,198,257)(H,200,251)(H,201,255)(H,202,259)(H,203,276)(H,204,238)(H,205,239)(H,206,237)(H,207,252)(H,208,253)(H,209,264)(H,210,260)(H,211,261)(H,212,274)(H,213,262)(H,214,254)(H,215,265)(H,216,266)(H,217,263)(H,218,271)(H,219,272)(H,220,277)(H,221,273)(H,222,275)(H,223,278)(H,224,240)(H,225,267)(H,226,270)(H,227,268)(H,228,269)(H,241,242)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,279,280)(H,281,282)(H4,184,185,192)(H4,186,187,193)(H4,188,189,194)/t97-,98-,99-,100-,101-,102+,103+,111-,113-,114-,115-,116-,117-,118-,119-,120-,121?,122?,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,144-,145-,146-,147-,148-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0270 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087738
(CHEMBL412541 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C172H265N43O51/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-53-129(224)195-116(170(265)266)59-64-128(223)180-68-41-40-50-109(148(243)187-84-137(236)237)193-130(225)81-184-149(244)110(51-42-69-181-171(175)176)200-165(260)138(91(7)8)212-158(253)118(72-90(5)6)203-157(252)122(76-103-79-183-108-49-39-38-48-106(103)108)201-146(241)97(15)192-167(262)140(93(11)19-2)214-159(254)120(73-100-44-33-31-34-45-100)204-154(249)115(62-67-135(232)233)199-153(248)111(52-43-70-182-172(177)178)196-144(239)95(13)189-143(238)94(12)191-152(247)114(58-63-127(174)222)194-131(226)82-185-151(246)113(61-66-134(230)231)198-155(250)117(71-89(3)4)202-156(251)119(75-102-54-56-105(221)57-55-102)205-162(257)124(85-216)208-164(259)126(87-218)209-166(261)139(92(9)10)213-161(256)123(78-136(234)235)206-163(258)125(86-217)210-169(264)142(99(17)220)215-160(255)121(74-101-46-35-32-36-47-101)207-168(263)141(98(16)219)211-132(227)83-186-150(245)112(60-65-133(228)229)197-145(240)96(14)190-147(242)107(173)77-104-80-179-88-188-104/h31-36,38-39,44-49,54-57,79-80,88-99,107,109-126,138-142,183,216-221H,18-30,37,40-43,50-53,58-78,81-87,173H2,1-17H3,(H2,174,222)(H,179,188)(H,180,223)(H,184,244)(H,185,246)(H,186,245)(H,187,243)(H,189,238)(H,190,242)(H,191,247)(H,192,262)(H,193,225)(H,194,226)(H,195,224)(H,196,239)(H,197,240)(H,198,250)(H,199,248)(H,200,260)(H,201,241)(H,202,251)(H,203,252)(H,204,249)(H,205,257)(H,206,258)(H,207,263)(H,208,259)(H,209,261)(H,210,264)(H,211,227)(H,212,253)(H,213,256)(H,214,254)(H,215,255)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,265,266)(H4,175,176,181)(H4,177,178,182)/t93-,94-,95-,96-,97-,98+,99+,107-,109-,110-,111-,112-,113-,114-,115-,116?,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,138-,139-,140-,141-,142-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0360 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087728
(CHEMBL412234 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(O)=O)C(O)=O Show InChI InChI=1S/C180H279N47O54/c1-17-19-20-21-22-23-24-25-26-27-28-29-36-54-134(236)206-121(177(280)281)60-66-133(235)190-71-40-39-50-120(176(278)279)212-159(261)118(63-69-141(245)246)209-157(259)113(52-42-73-192-179(185)186)203-136(238)86-196-153(255)112(51-41-72-191-178(183)184)211-171(273)144(95(7)8)224-164(266)123(76-94(5)6)215-163(265)127(80-106-83-194-111-49-38-37-48-109(106)111)213-151(253)100(14)202-173(275)146(97(11)18-2)226-165(267)125(77-103-44-32-30-33-45-103)216-160(262)119(64-70-142(247)248)210-158(260)114(53-43-74-193-180(187)188)207-150(252)99(13)200-149(251)98(12)201-156(258)117(59-65-132(182)234)205-137(239)87-197-155(257)116(62-68-140(243)244)208-161(263)122(75-93(3)4)214-162(264)124(79-105-55-57-108(233)58-56-105)217-168(270)129(89-228)220-170(272)131(91-230)221-172(274)145(96(9)10)225-167(269)128(82-143(249)250)218-169(271)130(90-229)222-175(277)148(102(16)232)227-166(268)126(78-104-46-34-31-35-47-104)219-174(276)147(101(15)231)223-138(240)88-198-154(256)115(61-67-139(241)242)204-135(237)85-195-152(254)110(181)81-107-84-189-92-199-107/h30-35,37-38,44-49,55-58,83-84,92-102,110,112-131,144-148,194,228-233H,17-29,36,39-43,50-54,59-82,85-91,181H2,1-16H3,(H2,182,234)(H,189,199)(H,190,235)(H,195,254)(H,196,255)(H,197,257)(H,198,256)(H,200,251)(H,201,258)(H,202,275)(H,203,238)(H,204,237)(H,205,239)(H,206,236)(H,207,252)(H,208,263)(H,209,259)(H,210,260)(H,211,273)(H,212,261)(H,213,253)(H,214,264)(H,215,265)(H,216,262)(H,217,270)(H,218,271)(H,219,276)(H,220,272)(H,221,274)(H,222,277)(H,223,240)(H,224,266)(H,225,269)(H,226,267)(H,227,268)(H,241,242)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,278,279)(H,280,281)(H4,183,184,191)(H4,185,186,192)(H4,187,188,193)/t97-,98-,99-,100-,101+,102+,110-,112-,113-,114-,115-,116-,117-,118-,119-,120?,121?,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,144-,145-,146-,147-,148-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.135 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087740
(CHEMBL437467 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCCC(NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(O)=O)C(O)=O Show InChI InChI=1S/C177H275N47O52/c1-17-19-20-21-22-23-24-25-26-27-28-29-36-54-132(233)204-119(174(275)276)60-65-131(232)187-69-40-39-50-118(173(273)274)205-136(237)86-193-151(251)111(51-41-70-188-175(180)181)201-134(235)84-194-152(252)112(52-42-71-189-176(182)183)209-168(268)142(94(7)8)221-161(261)121(74-93(5)6)212-160(260)125(78-105-81-191-110-49-38-37-48-108(105)110)210-149(249)99(14)200-170(270)144(96(11)18-2)223-162(262)123(75-102-44-32-30-33-45-102)213-157(257)117(63-68-140(243)244)208-156(256)113(53-43-72-190-177(184)185)206-148(248)98(13)198-147(247)97(12)199-155(255)116(59-64-130(179)231)203-135(236)85-195-154(254)115(62-67-139(241)242)207-158(258)120(73-92(3)4)211-159(259)122(77-104-55-57-107(230)58-56-104)214-165(265)127(88-225)217-167(267)129(90-227)218-169(269)143(95(9)10)222-164(264)126(80-141(245)246)215-166(266)128(89-226)219-172(272)146(101(16)229)224-163(263)124(76-103-46-34-31-35-47-103)216-171(271)145(100(15)228)220-137(238)87-196-153(253)114(61-66-138(239)240)202-133(234)83-192-150(250)109(178)79-106-82-186-91-197-106/h30-35,37-38,44-49,55-58,81-82,91-101,109,111-129,142-146,191,225-230H,17-29,36,39-43,50-54,59-80,83-90,178H2,1-16H3,(H2,179,231)(H,186,197)(H,187,232)(H,192,250)(H,193,251)(H,194,252)(H,195,254)(H,196,253)(H,198,247)(H,199,255)(H,200,270)(H,201,235)(H,202,234)(H,203,236)(H,204,233)(H,205,237)(H,206,248)(H,207,258)(H,208,256)(H,209,268)(H,210,249)(H,211,259)(H,212,260)(H,213,257)(H,214,265)(H,215,266)(H,216,271)(H,217,267)(H,218,269)(H,219,272)(H,220,238)(H,221,261)(H,222,264)(H,223,262)(H,224,263)(H,239,240)(H,241,242)(H,243,244)(H,245,246)(H,273,274)(H,275,276)(H4,180,181,188)(H4,182,183,189)(H4,184,185,190)/t96-,97-,98-,99-,100+,101+,109-,111-,112-,113-,114-,115-,116-,117-,118?,119?,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,142-,143-,144-,145-,146-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.328 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087732
(CHEMBL424733 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)CCc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C172H264N42O51/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-53-129(223)194-116(170(264)265)60-66-128(222)179-70-41-40-50-111(153(247)198-115(63-69-136(232)233)154(248)203-120(75-101-44-33-31-34-45-101)159(253)213-141(94(11)19-2)167(261)191-98(15)147(241)200-122(78-104-80-182-108-49-39-38-48-107(104)108)157(251)202-118(74-91(5)6)158(252)211-139(92(7)8)165(259)199-110(52-43-72-181-172(176)177)149(243)183-82-131(225)192-109(51-42-71-180-171(174)175)148(242)186-85-138(236)237)195-146(240)97(14)189-144(238)96(13)190-152(246)114(59-64-127(173)221)193-132(226)83-184-151(245)113(62-68-135(230)231)197-155(249)117(73-90(3)4)201-156(250)119(77-103-54-57-106(220)58-55-103)204-162(256)124(86-215)207-164(258)126(88-217)208-166(260)140(93(9)10)212-161(255)123(79-137(234)235)205-163(257)125(87-216)209-169(263)143(100(17)219)214-160(254)121(76-102-46-35-32-36-47-102)206-168(262)142(99(16)218)210-133(227)84-185-150(244)112(61-67-134(228)229)196-145(239)95(12)188-130(224)65-56-105-81-178-89-187-105/h31-36,38-39,44-49,54-55,57-58,80-81,89-100,109-126,139-143,182,215-220H,18-30,37,40-43,50-53,56,59-79,82-88H2,1-17H3,(H2,173,221)(H,178,187)(H,179,222)(H,183,243)(H,184,245)(H,185,244)(H,186,242)(H,188,224)(H,189,238)(H,190,246)(H,191,261)(H,192,225)(H,193,226)(H,194,223)(H,195,240)(H,196,239)(H,197,249)(H,198,247)(H,199,259)(H,200,241)(H,201,250)(H,202,251)(H,203,248)(H,204,256)(H,205,257)(H,206,262)(H,207,258)(H,208,260)(H,209,263)(H,210,227)(H,211,252)(H,212,255)(H,213,253)(H,214,254)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,264,265)(H4,174,175,180)(H4,176,177,181)/t94-,95-,96-,97-,98-,99+,100+,109-,110-,111-,112-,113-,114-,115-,116?,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,139-,140-,141-,142-,143-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.687 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087735
(CHEMBL428152 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCC(CCCCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C167H256N42O50/c1-18-20-21-22-23-24-31-44-99(165(258)259)45-32-35-51-124(217)175-64-37-36-48-106(143(236)182-80-132(229)230)188-125(218)77-179-144(237)107(49-38-65-176-166(170)171)194-160(253)133(87(7)8)206-153(246)114(68-86(5)6)197-152(245)118(72-100-75-178-105-47-34-33-46-103(100)105)195-141(234)93(15)187-162(255)135(89(11)19-2)208-154(247)116(69-96-40-27-25-28-41-96)198-149(242)112(59-63-130(225)226)193-148(241)108(50-39-66-177-167(172)173)190-139(232)91(13)184-138(231)90(12)186-147(240)111(56-60-123(169)216)189-126(219)78-180-146(239)110(58-62-129(223)224)192-150(243)113(67-85(3)4)196-151(244)115(71-98-52-54-102(215)55-53-98)199-157(250)120(81-210)202-159(252)122(83-212)203-161(254)134(88(9)10)207-156(249)119(74-131(227)228)200-158(251)121(82-211)204-164(257)137(95(17)214)209-155(248)117(70-97-42-29-26-30-43-97)201-163(256)136(94(16)213)205-127(220)79-181-145(238)109(57-61-128(221)222)191-140(233)92(14)185-142(235)104(168)73-101-76-174-84-183-101/h25-30,33-34,40-43,46-47,52-55,75-76,84-95,99,104,106-122,133-137,178,210-215H,18-24,31-32,35-39,44-45,48-51,56-74,77-83,168H2,1-17H3,(H2,169,216)(H,174,183)(H,175,217)(H,179,237)(H,180,239)(H,181,238)(H,182,236)(H,184,231)(H,185,235)(H,186,240)(H,187,255)(H,188,218)(H,189,219)(H,190,232)(H,191,233)(H,192,243)(H,193,241)(H,194,253)(H,195,234)(H,196,244)(H,197,245)(H,198,242)(H,199,250)(H,200,251)(H,201,256)(H,202,252)(H,203,254)(H,204,257)(H,205,220)(H,206,246)(H,207,249)(H,208,247)(H,209,248)(H,221,222)(H,223,224)(H,225,226)(H,227,228)(H,229,230)(H,258,259)(H4,170,171,176)(H4,172,173,177)/t89-,90-,91-,92-,93-,94+,95+,99?,104-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,133-,134-,135-,136-,137-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.00800 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087747
(CHEMBL439305 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C172H265N43O51/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-53-129(224)195-116(170(265)266)59-64-128(223)180-68-41-40-50-111(153(248)199-115(62-67-135(232)233)154(249)204-120(73-100-44-33-31-34-45-100)159(254)214-140(93(11)19-2)167(262)192-97(15)146(241)201-122(76-103-79-183-108-49-39-38-48-106(103)108)157(252)203-118(72-90(5)6)158(253)212-138(91(7)8)165(260)200-110(52-43-70-182-172(177)178)149(244)184-81-130(225)193-109(51-42-69-181-171(175)176)148(243)187-84-137(236)237)196-144(239)95(13)189-143(238)94(12)191-152(247)114(58-63-127(174)222)194-131(226)82-185-151(246)113(61-66-134(230)231)198-155(250)117(71-89(3)4)202-156(251)119(75-102-54-56-105(221)57-55-102)205-162(257)124(85-216)208-164(259)126(87-218)209-166(261)139(92(9)10)213-161(256)123(78-136(234)235)206-163(258)125(86-217)210-169(264)142(99(17)220)215-160(255)121(74-101-46-35-32-36-47-101)207-168(263)141(98(16)219)211-132(227)83-186-150(245)112(60-65-133(228)229)197-145(240)96(14)190-147(242)107(173)77-104-80-179-88-188-104/h31-36,38-39,44-49,54-57,79-80,88-99,107,109-126,138-142,183,216-221H,18-30,37,40-43,50-53,58-78,81-87,173H2,1-17H3,(H2,174,222)(H,179,188)(H,180,223)(H,184,244)(H,185,246)(H,186,245)(H,187,243)(H,189,238)(H,190,242)(H,191,247)(H,192,262)(H,193,225)(H,194,226)(H,195,224)(H,196,239)(H,197,240)(H,198,250)(H,199,248)(H,200,260)(H,201,241)(H,202,251)(H,203,252)(H,204,249)(H,205,257)(H,206,258)(H,207,263)(H,208,259)(H,209,261)(H,210,264)(H,211,227)(H,212,253)(H,213,256)(H,214,254)(H,215,255)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,265,266)(H4,175,176,181)(H4,177,178,182)/t93-,94-,95-,96-,97-,98+,99+,107-,109-,110-,111-,112-,113-,114-,115-,116?,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,138-,139-,140-,141-,142-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 61 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087730
(CHEMBL427768 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCC(CCCCC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCNC(=O)CCCCC(CCCCC)C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C175H268N40O53/c1-19-22-26-47-105(173(265)266)49-32-36-56-131(223)181-70-40-38-53-114(152(244)185-83-133(225)194-113(55-42-72-183-175(178)179)151(243)188-86-140(236)237)200-168(260)141(93(8)9)212-161(253)121(74-92(6)7)203-160(252)125(78-107-81-184-112-52-35-34-51-110(107)112)201-149(241)99(16)193-170(262)143(95(12)21-3)214-162(254)123(75-102-43-28-24-29-44-102)204-157(249)119(65-69-138(232)233)199-156(248)115(54-39-41-71-182-132(224)57-37-33-50-106(174(267)268)48-27-23-20-2)196-147(239)97(14)190-146(238)96(13)192-155(247)118(62-66-130(177)222)195-134(226)84-186-154(246)117(64-68-137(230)231)198-158(250)120(73-91(4)5)202-159(251)122(77-104-58-60-109(221)61-59-104)205-165(257)127(87-216)208-167(259)129(89-218)209-169(261)142(94(10)11)213-164(256)126(80-139(234)235)206-166(258)128(88-217)210-172(264)145(101(18)220)215-163(255)124(76-103-45-30-25-31-46-103)207-171(263)144(100(17)219)211-135(227)85-187-153(245)116(63-67-136(228)229)197-148(240)98(15)191-150(242)111(176)79-108-82-180-90-189-108/h24-25,28-31,34-35,43-46,51-52,58-61,81-82,90-101,105-106,111,113-129,141-145,184,216-221H,19-23,26-27,32-33,36-42,47-50,53-57,62-80,83-89,176H2,1-18H3,(H2,177,222)(H,180,189)(H,181,223)(H,182,224)(H,185,244)(H,186,246)(H,187,245)(H,188,243)(H,190,238)(H,191,242)(H,192,247)(H,193,262)(H,194,225)(H,195,226)(H,196,239)(H,197,240)(H,198,250)(H,199,248)(H,200,260)(H,201,241)(H,202,251)(H,203,252)(H,204,249)(H,205,257)(H,206,258)(H,207,263)(H,208,259)(H,209,261)(H,210,264)(H,211,227)(H,212,253)(H,213,256)(H,214,254)(H,215,255)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,265,266)(H,267,268)(H4,178,179,183)/t95-,96-,97-,98-,99-,100+,101+,105?,106?,111-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,141-,142-,143-,144-,145-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.177 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087736
(CHEMBL412948 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C168H257N43O51/c1-18-20-21-22-23-24-25-26-33-49-125(220)191-112(166(261)262)55-60-124(219)176-64-37-36-46-107(149(244)195-111(58-63-131(228)229)150(245)200-116(69-96-40-29-27-30-41-96)155(250)210-136(89(11)19-2)163(258)188-93(15)142(237)197-118(72-99-75-179-104-45-35-34-44-102(99)104)153(248)199-114(68-86(5)6)154(249)208-134(87(7)8)161(256)196-106(48-39-66-178-168(173)174)145(240)180-77-126(221)189-105(47-38-65-177-167(171)172)144(239)183-80-133(232)233)192-140(235)91(13)185-139(234)90(12)187-148(243)110(54-59-123(170)218)190-127(222)78-181-147(242)109(57-62-130(226)227)194-151(246)113(67-85(3)4)198-152(247)115(71-98-50-52-101(217)53-51-98)201-158(253)120(81-212)204-160(255)122(83-214)205-162(257)135(88(9)10)209-157(252)119(74-132(230)231)202-159(254)121(82-213)206-165(260)138(95(17)216)211-156(251)117(70-97-42-31-28-32-43-97)203-164(259)137(94(16)215)207-128(223)79-182-146(241)108(56-61-129(224)225)193-141(236)92(14)186-143(238)103(169)73-100-76-175-84-184-100/h27-32,34-35,40-45,50-53,75-76,84-95,103,105-122,134-138,179,212-217H,18-26,33,36-39,46-49,54-74,77-83,169H2,1-17H3,(H2,170,218)(H,175,184)(H,176,219)(H,180,240)(H,181,242)(H,182,241)(H,183,239)(H,185,234)(H,186,238)(H,187,243)(H,188,258)(H,189,221)(H,190,222)(H,191,220)(H,192,235)(H,193,236)(H,194,246)(H,195,244)(H,196,256)(H,197,237)(H,198,247)(H,199,248)(H,200,245)(H,201,253)(H,202,254)(H,203,259)(H,204,255)(H,205,257)(H,206,260)(H,207,223)(H,208,249)(H,209,252)(H,210,250)(H,211,251)(H,224,225)(H,226,227)(H,228,229)(H,230,231)(H,232,233)(H,261,262)(H4,171,172,177)(H4,173,174,178)/t89-,90-,91-,92-,93-,94+,95+,103-,105-,106-,107-,108-,109-,110-,111-,112?,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,134-,135-,136-,137-,138-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0270 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087752
(CHEMBL429398 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C173H269N45O50/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-55-129(226)198-117(170(267)268)60-64-128(225)182-68-41-40-51-112(152(249)194-95(12)143(240)192-96(13)144(241)199-113(54-44-71-185-173(179)180)153(250)202-116(63-67-135(234)235)154(251)207-121(74-101-45-33-31-34-46-101)159(256)217-140(94(11)19-2)167(264)195-98(15)146(243)204-123(77-104-80-186-109-50-39-38-49-107(104)109)157(254)206-119(73-91(5)6)158(255)215-138(92(7)8)165(262)203-111(53-43-70-184-172(177)178)149(246)187-82-130(227)196-110(52-42-69-183-171(175)176)148(245)190-85-137(238)239)197-131(228)83-188-151(248)115(62-66-134(232)233)201-155(252)118(72-90(3)4)205-156(253)120(76-103-56-58-106(224)59-57-103)208-162(259)125(86-219)211-164(261)127(88-221)212-166(263)139(93(9)10)216-161(258)124(79-136(236)237)209-163(260)126(87-220)213-169(266)142(100(17)223)218-160(257)122(75-102-47-35-32-36-48-102)210-168(265)141(99(16)222)214-132(229)84-189-150(247)114(61-65-133(230)231)200-145(242)97(14)193-147(244)108(174)78-105-81-181-89-191-105/h31-36,38-39,45-50,56-59,80-81,89-100,108,110-127,138-142,186,219-224H,18-30,37,40-44,51-55,60-79,82-88,174H2,1-17H3,(H,181,191)(H,182,225)(H,187,246)(H,188,248)(H,189,247)(H,190,245)(H,192,240)(H,193,244)(H,194,249)(H,195,264)(H,196,227)(H,197,228)(H,198,226)(H,199,241)(H,200,242)(H,201,252)(H,202,250)(H,203,262)(H,204,243)(H,205,253)(H,206,254)(H,207,251)(H,208,259)(H,209,260)(H,210,265)(H,211,261)(H,212,263)(H,213,266)(H,214,229)(H,215,255)(H,216,258)(H,217,256)(H,218,257)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,238,239)(H,267,268)(H4,175,176,183)(H4,177,178,184)(H4,179,180,185)/t94-,95-,96-,97-,98-,99+,100+,108-,110-,111-,112-,113-,114-,115-,116-,117?,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,138-,139-,140-,141-,142-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087751
(CHEMBL269543 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCCC(NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(O)=O)C(O)=O Show InChI InChI=1S/C178H277N47O52/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-55-133(234)204-120(175(276)277)61-66-132(233)188-70-41-40-51-119(174(274)275)205-136(237)86-193-152(252)112(52-42-71-189-176(181)182)202-134(235)84-194-153(253)113(53-43-72-190-177(183)184)210-169(269)142(94(7)8)222-162(262)122(75-93(5)6)213-161(261)126(79-106-82-192-111-50-39-38-49-109(106)111)211-150(250)100(15)201-171(271)144(96(11)19-2)224-163(263)124(76-103-45-33-31-34-46-103)214-158(258)118(64-69-140(243)244)209-157(257)114(54-44-73-191-178(185)186)206-148(248)98(13)198-147(247)97(12)200-156(256)117(60-65-131(180)232)203-135(236)85-195-155(255)116(63-68-139(241)242)208-159(259)121(74-92(3)4)212-160(260)123(78-105-56-58-108(231)59-57-105)215-166(266)128(88-226)218-168(268)130(90-228)219-170(270)143(95(9)10)223-165(265)127(81-141(245)246)216-167(267)129(89-227)220-173(273)146(102(17)230)225-164(264)125(77-104-47-35-32-36-48-104)217-172(272)145(101(16)229)221-137(238)87-196-154(254)115(62-67-138(239)240)207-149(249)99(14)199-151(251)110(179)80-107-83-187-91-197-107/h31-36,38-39,45-50,56-59,82-83,91-102,110,112-130,142-146,192,226-231H,18-30,37,40-44,51-55,60-81,84-90,179H2,1-17H3,(H2,180,232)(H,187,197)(H,188,233)(H,193,252)(H,194,253)(H,195,255)(H,196,254)(H,198,247)(H,199,251)(H,200,256)(H,201,271)(H,202,235)(H,203,236)(H,204,234)(H,205,237)(H,206,248)(H,207,249)(H,208,259)(H,209,257)(H,210,269)(H,211,250)(H,212,260)(H,213,261)(H,214,258)(H,215,266)(H,216,267)(H,217,272)(H,218,268)(H,219,270)(H,220,273)(H,221,238)(H,222,262)(H,223,265)(H,224,263)(H,225,264)(H,239,240)(H,241,242)(H,243,244)(H,245,246)(H,274,275)(H,276,277)(H4,181,182,189)(H4,183,184,190)(H4,185,186,191)/t96-,97-,98-,99-,100-,101+,102+,110-,112-,113-,114-,115-,116-,117-,118-,119?,120?,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,142-,143-,144-,145-,146-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0530 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087759
(CHEMBL414971 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C175H272N46O50/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-55-131(229)201-119(172(270)271)61-66-130(228)185-70-41-40-51-113(204-165(263)127(88-222)215-168(266)141(94(9)10)219-164(262)126(81-138(239)240)213-166(264)128(89-223)216-171(269)144(101(17)225)221-163(261)124(77-103-47-35-32-36-48-103)214-170(268)143(100(16)224)217-134(232)86-192-152(250)115(62-67-135(233)234)203-147(245)98(14)196-149(247)109(176)80-106-83-184-90-194-106)156(254)211-122(78-104-56-58-107(226)59-57-104)159(257)209-120(74-91(3)4)158(256)205-116(63-68-136(235)236)153(251)191-85-133(231)200-117(60-65-129(177)227)154(252)197-96(12)145(243)195-97(13)146(244)202-114(54-44-73-188-175(182)183)155(253)206-118(64-69-137(237)238)157(255)212-123(76-102-45-33-31-34-46-102)162(260)220-142(95(11)19-2)169(267)198-99(15)148(246)208-125(79-105-82-189-110-50-39-38-49-108(105)110)160(258)210-121(75-92(5)6)161(259)218-140(93(7)8)167(265)207-112(53-43-72-187-174(180)181)151(249)190-84-132(230)199-111(52-42-71-186-173(178)179)150(248)193-87-139(241)242/h31-36,38-39,45-50,56-59,82-83,90-101,109,111-128,140-144,189,222-226H,18-30,37,40-44,51-55,60-81,84-89,176H2,1-17H3,(H2,177,227)(H,184,194)(H,185,228)(H,190,249)(H,191,251)(H,192,250)(H,193,248)(H,195,243)(H,196,247)(H,197,252)(H,198,267)(H,199,230)(H,200,231)(H,201,229)(H,202,244)(H,203,245)(H,204,263)(H,205,256)(H,206,253)(H,207,265)(H,208,246)(H,209,257)(H,210,258)(H,211,254)(H,212,255)(H,213,264)(H,214,268)(H,215,266)(H,216,269)(H,217,232)(H,218,259)(H,219,262)(H,220,260)(H,221,261)(H,233,234)(H,235,236)(H,237,238)(H,239,240)(H,241,242)(H,270,271)(H4,178,179,186)(H4,180,181,187)(H4,182,183,188)/t95-,96-,97-,98-,99-,100+,101+,109-,111-,112-,113-,114-,115-,116-,117-,118-,119?,120-,121-,122-,123-,124-,125-,126-,127-,128-,140-,141-,142-,143-,144-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0350 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087733
(CHEMBL440075 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCC(CCCCC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCNC(=O)CCCCC(CCCCCCCCC)C(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C183H284N40O53/c1-19-22-24-26-28-30-38-55-113(181(273)274)57-40-44-64-139(231)189-78-48-46-61-122(160(252)193-91-141(233)202-121(63-50-80-191-183(186)187)159(251)196-94-148(244)245)208-176(268)149(101(8)9)220-169(261)129(82-100(6)7)211-168(260)133(86-115-89-192-120-60-43-42-59-118(115)120)209-157(249)107(16)201-178(270)151(103(12)21-3)222-170(262)131(83-110-51-34-32-35-52-110)212-165(257)127(73-77-146(240)241)207-164(256)123(62-47-49-79-190-140(232)65-45-41-58-114(182(275)276)56-39-31-29-27-25-23-20-2)204-155(247)105(14)198-154(246)104(13)200-163(255)126(70-74-138(185)230)203-142(234)92-194-162(254)125(72-76-145(238)239)206-166(258)128(81-99(4)5)210-167(259)130(85-112-66-68-117(229)69-67-112)213-173(265)135(95-224)216-175(267)137(97-226)217-177(269)150(102(10)11)221-172(264)134(88-147(242)243)214-174(266)136(96-225)218-180(272)153(109(18)228)223-171(263)132(84-111-53-36-33-37-54-111)215-179(271)152(108(17)227)219-143(235)93-195-161(253)124(71-75-144(236)237)205-156(248)106(15)199-158(250)119(184)87-116-90-188-98-197-116/h32-37,42-43,51-54,59-60,66-69,89-90,98-109,113-114,119,121-137,149-153,192,224-229H,19-31,38-41,44-50,55-58,61-65,70-88,91-97,184H2,1-18H3,(H2,185,230)(H,188,197)(H,189,231)(H,190,232)(H,193,252)(H,194,254)(H,195,253)(H,196,251)(H,198,246)(H,199,250)(H,200,255)(H,201,270)(H,202,233)(H,203,234)(H,204,247)(H,205,248)(H,206,258)(H,207,256)(H,208,268)(H,209,249)(H,210,259)(H,211,260)(H,212,257)(H,213,265)(H,214,266)(H,215,271)(H,216,267)(H,217,269)(H,218,272)(H,219,235)(H,220,261)(H,221,264)(H,222,262)(H,223,263)(H,236,237)(H,238,239)(H,240,241)(H,242,243)(H,244,245)(H,273,274)(H,275,276)(H4,186,187,191)/t103-,104-,105-,106-,107-,108+,109+,113?,114?,119-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,149-,150-,151-,152-,153-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087741
(CHEMBL266046 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C175H272N46O51/c1-17-19-20-21-22-23-24-25-26-27-28-29-36-54-131(230)200-118(172(271)272)60-65-130(229)185-69-40-39-50-112(202-148(247)108(176)79-105-82-184-90-194-105)154(253)203-114(61-66-135(234)235)151(250)192-85-134(233)217-143(99(15)225)170(269)213-123(76-102-46-34-31-35-47-102)162(261)221-144(100(16)226)171(270)216-127(88-223)165(264)212-125(80-138(240)241)163(262)219-141(94(9)10)168(267)215-128(89-224)166(265)214-126(87-222)164(263)211-121(77-103-55-57-106(227)58-56-103)158(257)208-119(73-91(3)4)157(256)204-115(62-67-136(236)237)152(251)191-84-133(232)199-116(59-64-129(177)228)153(252)196-96(12)145(244)195-97(13)146(245)201-113(53-43-72-188-175(182)183)155(254)205-117(63-68-137(238)239)156(255)210-122(75-101-44-32-30-33-45-101)161(260)220-142(95(11)18-2)169(268)197-98(14)147(246)207-124(78-104-81-189-109-49-38-37-48-107(104)109)159(258)209-120(74-92(5)6)160(259)218-140(93(7)8)167(266)206-111(52-42-71-187-174(180)181)150(249)190-83-132(231)198-110(51-41-70-186-173(178)179)149(248)193-86-139(242)243/h30-35,37-38,44-49,55-58,81-82,90-100,108,110-128,140-144,189,222-227H,17-29,36,39-43,50-54,59-80,83-89,176H2,1-16H3,(H2,177,228)(H,184,194)(H,185,229)(H,190,249)(H,191,251)(H,192,250)(H,193,248)(H,195,244)(H,196,252)(H,197,268)(H,198,231)(H,199,232)(H,200,230)(H,201,245)(H,202,247)(H,203,253)(H,204,256)(H,205,254)(H,206,266)(H,207,246)(H,208,257)(H,209,258)(H,210,255)(H,211,263)(H,212,264)(H,213,269)(H,214,265)(H,215,267)(H,216,270)(H,217,233)(H,218,259)(H,219,262)(H,220,260)(H,221,261)(H,234,235)(H,236,237)(H,238,239)(H,240,241)(H,242,243)(H,271,272)(H4,178,179,186)(H4,180,181,187)(H4,182,183,188)/t95-,96-,97-,98-,99+,100+,108-,110-,111-,112-,113-,114-,115-,116-,117-,118?,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,140-,141-,142-,143-,144-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.26 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087760
(CHEMBL439091 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCC(CCCCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C171H264N42O50/c1-18-20-21-22-23-24-25-26-27-28-35-48-103(169(262)263)49-36-39-55-128(221)179-68-41-40-52-110(147(240)186-84-136(233)234)192-129(222)81-183-148(241)111(53-42-69-180-170(174)175)198-164(257)137(91(7)8)210-157(250)118(72-90(5)6)201-156(249)122(76-104-79-182-109-51-38-37-50-107(104)109)199-145(238)97(15)191-166(259)139(93(11)19-2)212-158(251)120(73-100-44-31-29-32-45-100)202-153(246)116(63-67-134(229)230)197-152(245)112(54-43-70-181-171(176)177)194-143(236)95(13)188-142(235)94(12)190-151(244)115(60-64-127(173)220)193-130(223)82-184-150(243)114(62-66-133(227)228)196-154(247)117(71-89(3)4)200-155(248)119(75-102-56-58-106(219)59-57-102)203-161(254)124(85-214)206-163(256)126(87-216)207-165(258)138(92(9)10)211-160(253)123(78-135(231)232)204-162(255)125(86-215)208-168(261)141(99(17)218)213-159(252)121(74-101-46-33-30-34-47-101)205-167(260)140(98(16)217)209-131(224)83-185-149(242)113(61-65-132(225)226)195-144(237)96(14)189-146(239)108(172)77-105-80-178-88-187-105/h29-34,37-38,44-47,50-51,56-59,79-80,88-99,103,108,110-126,137-141,182,214-219H,18-28,35-36,39-43,48-49,52-55,60-78,81-87,172H2,1-17H3,(H2,173,220)(H,178,187)(H,179,221)(H,183,241)(H,184,243)(H,185,242)(H,186,240)(H,188,235)(H,189,239)(H,190,244)(H,191,259)(H,192,222)(H,193,223)(H,194,236)(H,195,237)(H,196,247)(H,197,245)(H,198,257)(H,199,238)(H,200,248)(H,201,249)(H,202,246)(H,203,254)(H,204,255)(H,205,260)(H,206,256)(H,207,258)(H,208,261)(H,209,224)(H,210,250)(H,211,253)(H,212,251)(H,213,252)(H,225,226)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H,262,263)(H4,174,175,180)(H4,176,177,181)/t93-,94-,95-,96-,97-,98+,99+,103?,108-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,137-,138-,139-,140-,141-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087748
(CHEMBL269494 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NCCCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O Show InChI InChI=1S/C171H265N43O49/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-54-128(222)180-69-44-55-129(223)179-68-41-40-51-112(153(247)198-116(63-67-135(231)232)154(248)203-120(74-101-45-33-31-34-46-101)159(253)213-140(94(11)19-2)167(261)192-98(15)146(240)200-122(77-104-80-183-109-50-39-38-49-107(104)109)157(251)202-118(73-91(5)6)158(252)211-138(92(7)8)165(259)199-111(53-43-71-182-171(176)177)149(243)184-82-130(224)193-110(52-42-70-181-170(174)175)148(242)187-85-137(235)236)195-144(238)96(13)189-143(237)95(12)191-152(246)115(60-64-127(173)221)194-131(225)83-185-151(245)114(62-66-134(229)230)197-155(249)117(72-90(3)4)201-156(250)119(76-103-56-58-106(220)59-57-103)204-162(256)124(86-215)207-164(258)126(88-217)208-166(260)139(93(9)10)212-161(255)123(79-136(233)234)205-163(257)125(87-216)209-169(263)142(100(17)219)214-160(254)121(75-102-47-35-32-36-48-102)206-168(262)141(99(16)218)210-132(226)84-186-150(244)113(61-65-133(227)228)196-145(239)97(14)190-147(241)108(172)78-105-81-178-89-188-105/h31-36,38-39,45-50,56-59,80-81,89-100,108,110-126,138-142,183,215-220H,18-30,37,40-44,51-55,60-79,82-88,172H2,1-17H3,(H2,173,221)(H,178,188)(H,179,223)(H,180,222)(H,184,243)(H,185,245)(H,186,244)(H,187,242)(H,189,237)(H,190,241)(H,191,246)(H,192,261)(H,193,224)(H,194,225)(H,195,238)(H,196,239)(H,197,249)(H,198,247)(H,199,259)(H,200,240)(H,201,250)(H,202,251)(H,203,248)(H,204,256)(H,205,257)(H,206,262)(H,207,258)(H,208,260)(H,209,263)(H,210,226)(H,211,252)(H,212,255)(H,213,253)(H,214,254)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H,235,236)(H4,174,175,181)(H4,176,177,182)/t94-,95-,96-,97-,98-,99+,100+,108-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,138-,139-,140-,141-,142-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0840 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087756
(CHEMBL439099 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCC(CCCCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C167H256N42O50/c1-18-20-21-22-23-24-31-44-99(165(258)259)45-32-35-51-124(217)175-64-37-36-48-108(148(241)193-112(59-63-130(225)226)149(242)198-116(69-96-40-27-25-28-41-96)154(247)208-135(89(11)19-2)162(255)187-93(15)141(234)195-118(72-100-75-178-105-47-34-33-46-103(100)105)152(245)197-114(68-86(5)6)153(246)206-133(87(7)8)160(253)194-107(50-39-66-177-167(172)173)144(237)179-77-125(218)188-106(49-38-65-176-166(170)171)143(236)182-80-132(229)230)190-139(232)91(13)184-138(231)90(12)186-147(240)111(56-60-123(169)216)189-126(219)78-180-146(239)110(58-62-129(223)224)192-150(243)113(67-85(3)4)196-151(244)115(71-98-52-54-102(215)55-53-98)199-157(250)120(81-210)202-159(252)122(83-212)203-161(254)134(88(9)10)207-156(249)119(74-131(227)228)200-158(251)121(82-211)204-164(257)137(95(17)214)209-155(248)117(70-97-42-29-26-30-43-97)201-163(256)136(94(16)213)205-127(220)79-181-145(238)109(57-61-128(221)222)191-140(233)92(14)185-142(235)104(168)73-101-76-174-84-183-101/h25-30,33-34,40-43,46-47,52-55,75-76,84-95,99,104,106-122,133-137,178,210-215H,18-24,31-32,35-39,44-45,48-51,56-74,77-83,168H2,1-17H3,(H2,169,216)(H,174,183)(H,175,217)(H,179,237)(H,180,239)(H,181,238)(H,182,236)(H,184,231)(H,185,235)(H,186,240)(H,187,255)(H,188,218)(H,189,219)(H,190,232)(H,191,233)(H,192,243)(H,193,241)(H,194,253)(H,195,234)(H,196,244)(H,197,245)(H,198,242)(H,199,250)(H,200,251)(H,201,256)(H,202,252)(H,203,254)(H,204,257)(H,205,220)(H,206,246)(H,207,249)(H,208,247)(H,209,248)(H,221,222)(H,223,224)(H,225,226)(H,227,228)(H,229,230)(H,258,259)(H4,170,171,176)(H4,172,173,177)/t89-,90-,91-,92-,93-,94+,95+,99?,104-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,133-,134-,135-,136-,137-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.154 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087757
(CHEMBL441931 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NCCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O Show InChI InChI=1S/C170H263N43O49/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-53-127(221)179-70-66-128(222)178-67-41-40-50-111(152(246)197-115(61-65-134(230)231)153(247)202-119(73-100-44-33-31-34-45-100)158(252)212-139(93(11)19-2)166(260)191-97(15)145(239)199-121(76-103-79-182-108-49-39-38-48-106(103)108)156(250)201-117(72-90(5)6)157(251)210-137(91(7)8)164(258)198-110(52-43-69-181-170(175)176)148(242)183-81-129(223)192-109(51-42-68-180-169(173)174)147(241)186-84-136(234)235)194-143(237)95(13)188-142(236)94(12)190-151(245)114(58-62-126(172)220)193-130(224)82-184-150(244)113(60-64-133(228)229)196-154(248)116(71-89(3)4)200-155(249)118(75-102-54-56-105(219)57-55-102)203-161(255)123(85-214)206-163(257)125(87-216)207-165(259)138(92(9)10)211-160(254)122(78-135(232)233)204-162(256)124(86-215)208-168(262)141(99(17)218)213-159(253)120(74-101-46-35-32-36-47-101)205-167(261)140(98(16)217)209-131(225)83-185-149(243)112(59-63-132(226)227)195-144(238)96(14)189-146(240)107(171)77-104-80-177-88-187-104/h31-36,38-39,44-49,54-57,79-80,88-99,107,109-125,137-141,182,214-219H,18-30,37,40-43,50-53,58-78,81-87,171H2,1-17H3,(H2,172,220)(H,177,187)(H,178,222)(H,179,221)(H,183,242)(H,184,244)(H,185,243)(H,186,241)(H,188,236)(H,189,240)(H,190,245)(H,191,260)(H,192,223)(H,193,224)(H,194,237)(H,195,238)(H,196,248)(H,197,246)(H,198,258)(H,199,239)(H,200,249)(H,201,250)(H,202,247)(H,203,255)(H,204,256)(H,205,261)(H,206,257)(H,207,259)(H,208,262)(H,209,225)(H,210,251)(H,211,254)(H,212,252)(H,213,253)(H,226,227)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H4,173,174,180)(H4,175,176,181)/t93-,94-,95-,96-,97-,98+,99+,107-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,137-,138-,139-,140-,141-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.113 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087761
(CHEMBL430245 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C173H267N43O51/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-54-130(225)196-117(171(266)267)60-65-129(224)181-69-42-40-52-111(150(245)185-82-131(226)194-110(149(244)188-85-138(237)238)51-41-43-70-182-172(176)177)201-166(261)139(92(7)8)213-159(254)119(73-91(5)6)204-158(253)123(77-104-80-184-109-50-39-38-49-107(104)109)202-147(242)98(15)193-168(263)141(94(11)19-2)215-160(255)121(74-101-45-33-31-34-46-101)205-155(250)116(63-68-136(233)234)200-154(249)112(53-44-71-183-173(178)179)197-145(240)96(13)190-144(239)95(12)192-153(248)115(59-64-128(175)223)195-132(227)83-186-152(247)114(62-67-135(231)232)199-156(251)118(72-90(3)4)203-157(252)120(76-103-55-57-106(222)58-56-103)206-163(258)125(86-217)209-165(260)127(88-219)210-167(262)140(93(9)10)214-162(257)124(79-137(235)236)207-164(259)126(87-218)211-170(265)143(100(17)221)216-161(256)122(75-102-47-35-32-36-48-102)208-169(264)142(99(16)220)212-133(228)84-187-151(246)113(61-66-134(229)230)198-146(241)97(14)191-148(243)108(174)78-105-81-180-89-189-105/h31-36,38-39,45-50,55-58,80-81,89-100,108,110-127,139-143,184,217-222H,18-30,37,40-44,51-54,59-79,82-88,174H2,1-17H3,(H2,175,223)(H,180,189)(H,181,224)(H,185,245)(H,186,247)(H,187,246)(H,188,244)(H,190,239)(H,191,243)(H,192,248)(H,193,263)(H,194,226)(H,195,227)(H,196,225)(H,197,240)(H,198,241)(H,199,251)(H,200,249)(H,201,261)(H,202,242)(H,203,252)(H,204,253)(H,205,250)(H,206,258)(H,207,259)(H,208,264)(H,209,260)(H,210,262)(H,211,265)(H,212,228)(H,213,254)(H,214,257)(H,215,255)(H,216,256)(H,229,230)(H,231,232)(H,233,234)(H,235,236)(H,237,238)(H,266,267)(H4,176,177,182)(H4,178,179,183)/t94-,95-,96-,97-,98-,99+,100+,108-,110-,111-,112-,113-,114-,115-,116-,117?,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,139-,140-,141-,142-,143-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.121 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087727
(CHEMBL437277 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)CCc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O Show InChI InChI=1S/C159H241N41O48/c1-18-20-21-22-29-45-117(208)166-60-33-32-42-100(137(228)170-72-119(210)179-99(43-34-61-167-158(161)162)136(227)173-75-126(221)222)185-153(244)127(82(7)8)197-146(237)107(64-81(5)6)188-145(236)111(68-94-70-169-98-41-31-30-40-97(94)98)186-135(226)88(15)178-155(246)129(84(11)19-2)199-147(238)109(65-91-36-25-23-26-37-91)189-142(233)105(54-59-124(217)218)184-141(232)101(44-35-62-168-159(163)164)181-134(225)87(14)176-132(223)86(13)177-140(231)104(51-55-116(160)207)180-120(211)73-171-139(230)103(53-58-123(215)216)183-143(234)106(63-80(3)4)187-144(235)108(67-93-46-49-96(206)50-47-93)190-150(241)113(76-201)193-152(243)115(78-203)194-154(245)128(83(9)10)198-149(240)112(69-125(219)220)191-151(242)114(77-202)195-157(248)131(90(17)205)200-148(239)110(66-92-38-27-24-28-39-92)192-156(247)130(89(16)204)196-121(212)74-172-138(229)102(52-57-122(213)214)182-133(224)85(12)175-118(209)56-48-95-71-165-79-174-95/h23-28,30-31,36-41,46-47,49-50,70-71,79-90,99-115,127-131,169,201-206H,18-22,29,32-35,42-45,48,51-69,72-78H2,1-17H3,(H2,160,207)(H,165,174)(H,166,208)(H,170,228)(H,171,230)(H,172,229)(H,173,227)(H,175,209)(H,176,223)(H,177,231)(H,178,246)(H,179,210)(H,180,211)(H,181,225)(H,182,224)(H,183,234)(H,184,232)(H,185,244)(H,186,226)(H,187,235)(H,188,236)(H,189,233)(H,190,241)(H,191,242)(H,192,247)(H,193,243)(H,194,245)(H,195,248)(H,196,212)(H,197,237)(H,198,240)(H,199,238)(H,200,239)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H,221,222)(H4,161,162,167)(H4,163,164,168)/t84-,85-,86-,87-,88-,89+,90+,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,127-,128-,129-,130-,131-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.236 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087744
(CHEMBL269779 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)CCc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C164H248N42O51/c1-18-20-21-22-29-45-121(215)186-108(162(256)257)52-58-120(214)171-62-33-32-42-102(141(235)175-74-123(217)184-101(43-34-63-172-163(166)167)140(234)178-77-130(228)229)191-157(251)131(84(7)8)203-150(244)110(66-83(5)6)194-149(243)114(70-96-72-174-100-41-31-30-40-99(96)100)192-139(233)90(15)183-159(253)133(86(11)19-2)205-151(245)112(67-93-36-25-23-26-37-93)195-146(240)107(55-61-128(224)225)190-145(239)103(44-35-64-173-164(168)169)187-138(232)89(14)181-136(230)88(13)182-144(238)106(51-56-119(165)213)185-124(218)75-176-143(237)105(54-60-127(222)223)189-147(241)109(65-82(3)4)193-148(242)111(69-95-46-49-98(212)50-47-95)196-154(248)116(78-207)199-156(250)118(80-209)200-158(252)132(85(9)10)204-153(247)115(71-129(226)227)197-155(249)117(79-208)201-161(255)135(92(17)211)206-152(246)113(68-94-38-27-24-28-39-94)198-160(254)134(91(16)210)202-125(219)76-177-142(236)104(53-59-126(220)221)188-137(231)87(12)180-122(216)57-48-97-73-170-81-179-97/h23-28,30-31,36-41,46-47,49-50,72-73,81-92,101-118,131-135,174,207-212H,18-22,29,32-35,42-45,48,51-71,74-80H2,1-17H3,(H2,165,213)(H,170,179)(H,171,214)(H,175,235)(H,176,237)(H,177,236)(H,178,234)(H,180,216)(H,181,230)(H,182,238)(H,183,253)(H,184,217)(H,185,218)(H,186,215)(H,187,232)(H,188,231)(H,189,241)(H,190,239)(H,191,251)(H,192,233)(H,193,242)(H,194,243)(H,195,240)(H,196,248)(H,197,249)(H,198,254)(H,199,250)(H,200,252)(H,201,255)(H,202,219)(H,203,244)(H,204,247)(H,205,245)(H,206,246)(H,220,221)(H,222,223)(H,224,225)(H,226,227)(H,228,229)(H,256,257)(H4,166,167,172)(H4,168,169,173)/t86-,87-,88-,89-,90-,91+,92+,101-,102-,103-,104-,105-,106-,107-,108?,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,131-,132-,133-,134-,135-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.169 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087753
(CHEMBL441203 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C174H269N43O51/c1-18-20-21-22-23-24-25-26-27-28-29-30-31-32-39-55-131(226)197-118(172(267)268)61-66-130(225)182-70-43-42-52-113(155(250)201-117(64-69-137(234)235)156(251)206-122(75-102-46-35-33-36-47-102)161(256)216-142(95(11)19-2)169(264)194-99(15)148(243)203-124(78-105-81-185-110-51-41-40-50-108(105)110)159(254)205-120(74-92(5)6)160(255)214-140(93(7)8)167(262)202-112(54-45-72-184-174(179)180)151(246)186-83-132(227)195-111(53-44-71-183-173(177)178)150(245)189-86-139(238)239)198-146(241)97(13)191-145(240)96(12)193-154(249)116(60-65-129(176)224)196-133(228)84-187-153(248)115(63-68-136(232)233)200-157(252)119(73-91(3)4)204-158(253)121(77-104-56-58-107(223)59-57-104)207-164(259)126(87-218)210-166(261)128(89-220)211-168(263)141(94(9)10)215-163(258)125(80-138(236)237)208-165(260)127(88-219)212-171(266)144(101(17)222)217-162(257)123(76-103-48-37-34-38-49-103)209-170(265)143(100(16)221)213-134(229)85-188-152(247)114(62-67-135(230)231)199-147(242)98(14)192-149(244)109(175)79-106-82-181-90-190-106/h33-38,40-41,46-51,56-59,81-82,90-101,109,111-128,140-144,185,218-223H,18-32,39,42-45,52-55,60-80,83-89,175H2,1-17H3,(H2,176,224)(H,181,190)(H,182,225)(H,186,246)(H,187,248)(H,188,247)(H,189,245)(H,191,240)(H,192,244)(H,193,249)(H,194,264)(H,195,227)(H,196,228)(H,197,226)(H,198,241)(H,199,242)(H,200,252)(H,201,250)(H,202,262)(H,203,243)(H,204,253)(H,205,254)(H,206,251)(H,207,259)(H,208,260)(H,209,265)(H,210,261)(H,211,263)(H,212,266)(H,213,229)(H,214,255)(H,215,258)(H,216,256)(H,217,257)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,238,239)(H,267,268)(H4,177,178,183)(H4,179,180,184)/t95-,96-,97-,98-,99-,100+,101+,109-,111-,112-,113-,114-,115-,116-,117-,118?,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,140-,141-,142-,143-,144-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.194 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087755
(CHEMBL438212 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)CCc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C172H264N42O51/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-53-129(223)194-116(170(264)265)60-66-128(222)179-70-41-40-50-110(149(243)183-82-131(225)192-109(51-42-71-180-171(174)175)148(242)186-85-138(236)237)199-165(259)139(92(7)8)211-158(252)118(74-91(5)6)202-157(251)122(78-104-80-182-108-49-39-38-48-107(104)108)200-147(241)98(15)191-167(261)141(94(11)19-2)213-159(253)120(75-101-44-33-31-34-45-101)203-154(248)115(63-69-136(232)233)198-153(247)111(52-43-72-181-172(176)177)195-146(240)97(14)189-144(238)96(13)190-152(246)114(59-64-127(173)221)193-132(226)83-184-151(245)113(62-68-135(230)231)197-155(249)117(73-90(3)4)201-156(250)119(77-103-54-57-106(220)58-55-103)204-162(256)124(86-215)207-164(258)126(88-217)208-166(260)140(93(9)10)212-161(255)123(79-137(234)235)205-163(257)125(87-216)209-169(263)143(100(17)219)214-160(254)121(76-102-46-35-32-36-47-102)206-168(262)142(99(16)218)210-133(227)84-185-150(244)112(61-67-134(228)229)196-145(239)95(12)188-130(224)65-56-105-81-178-89-187-105/h31-36,38-39,44-49,54-55,57-58,80-81,89-100,109-126,139-143,182,215-220H,18-30,37,40-43,50-53,56,59-79,82-88H2,1-17H3,(H2,173,221)(H,178,187)(H,179,222)(H,183,243)(H,184,245)(H,185,244)(H,186,242)(H,188,224)(H,189,238)(H,190,246)(H,191,261)(H,192,225)(H,193,226)(H,194,223)(H,195,240)(H,196,239)(H,197,249)(H,198,247)(H,199,259)(H,200,241)(H,201,250)(H,202,251)(H,203,248)(H,204,256)(H,205,257)(H,206,262)(H,207,258)(H,208,260)(H,209,263)(H,210,227)(H,211,252)(H,212,255)(H,213,253)(H,214,254)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,264,265)(H4,174,175,180)(H4,176,177,181)/t94-,95-,96-,97-,98-,99+,100+,109-,110-,111-,112-,113-,114-,115-,116?,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,139-,140-,141-,142-,143-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.36 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087754
(CHEMBL411170 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C170H261N43O51/c1-18-20-21-22-23-24-25-26-27-28-35-51-127(222)193-114(168(263)264)57-62-126(221)178-66-39-38-48-109(151(246)197-113(60-65-133(230)231)152(247)202-118(71-98-42-31-29-32-43-98)157(252)212-138(91(11)19-2)165(260)190-95(15)144(239)199-120(74-101-77-181-106-47-37-36-46-104(101)106)155(250)201-116(70-88(5)6)156(251)210-136(89(7)8)163(258)198-108(50-41-68-180-170(175)176)147(242)182-79-128(223)191-107(49-40-67-179-169(173)174)146(241)185-82-135(234)235)194-142(237)93(13)187-141(236)92(12)189-150(245)112(56-61-125(172)220)192-129(224)80-183-149(244)111(59-64-132(228)229)196-153(248)115(69-87(3)4)200-154(249)117(73-100-52-54-103(219)55-53-100)203-160(255)122(83-214)206-162(257)124(85-216)207-164(259)137(90(9)10)211-159(254)121(76-134(232)233)204-161(256)123(84-215)208-167(262)140(97(17)218)213-158(253)119(72-99-44-33-30-34-45-99)205-166(261)139(96(16)217)209-130(225)81-184-148(243)110(58-63-131(226)227)195-143(238)94(14)188-145(240)105(171)75-102-78-177-86-186-102/h29-34,36-37,42-47,52-55,77-78,86-97,105,107-124,136-140,181,214-219H,18-28,35,38-41,48-51,56-76,79-85,171H2,1-17H3,(H2,172,220)(H,177,186)(H,178,221)(H,182,242)(H,183,244)(H,184,243)(H,185,241)(H,187,236)(H,188,240)(H,189,245)(H,190,260)(H,191,223)(H,192,224)(H,193,222)(H,194,237)(H,195,238)(H,196,248)(H,197,246)(H,198,258)(H,199,239)(H,200,249)(H,201,250)(H,202,247)(H,203,255)(H,204,256)(H,205,261)(H,206,257)(H,207,259)(H,208,262)(H,209,225)(H,210,251)(H,211,254)(H,212,252)(H,213,253)(H,226,227)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,263,264)(H4,173,174,179)(H4,175,176,180)/t91-,92-,93-,94-,95-,96+,97+,105-,107-,108-,109-,110-,111-,112-,113-,114?,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,136-,137-,138-,139-,140-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0220 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087729
(CHEMBL439181 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(O)=O)C(O)=O Show InChI InChI=1S/C182H283N47O54/c1-17-19-20-21-22-23-24-25-26-27-28-29-30-31-38-56-136(238)208-123(179(282)283)62-68-135(237)192-73-42-41-52-122(178(280)281)214-161(263)120(65-71-143(247)248)211-159(261)115(54-44-75-194-181(187)188)205-138(240)88-198-155(257)114(53-43-74-193-180(185)186)213-173(275)146(97(7)8)226-166(268)125(78-96(5)6)217-165(267)129(82-108-85-196-113-51-40-39-50-111(108)113)215-153(255)102(14)204-175(277)148(99(11)18-2)228-167(269)127(79-105-46-34-32-35-47-105)218-162(264)121(66-72-144(249)250)212-160(262)116(55-45-76-195-182(189)190)209-152(254)101(13)202-151(253)100(12)203-158(260)119(61-67-134(184)236)207-139(241)89-199-157(259)118(64-70-142(245)246)210-163(265)124(77-95(3)4)216-164(266)126(81-107-57-59-110(235)60-58-107)219-170(272)131(91-230)222-172(274)133(93-232)223-174(276)147(98(9)10)227-169(271)130(84-145(251)252)220-171(273)132(92-231)224-177(279)150(104(16)234)229-168(270)128(80-106-48-36-33-37-49-106)221-176(278)149(103(15)233)225-140(242)90-200-156(258)117(63-69-141(243)244)206-137(239)87-197-154(256)112(183)83-109-86-191-94-201-109/h32-37,39-40,46-51,57-60,85-86,94-104,112,114-133,146-150,196,230-235H,17-31,38,41-45,52-56,61-84,87-93,183H2,1-16H3,(H2,184,236)(H,191,201)(H,192,237)(H,197,256)(H,198,257)(H,199,259)(H,200,258)(H,202,253)(H,203,260)(H,204,277)(H,205,240)(H,206,239)(H,207,241)(H,208,238)(H,209,254)(H,210,265)(H,211,261)(H,212,262)(H,213,275)(H,214,263)(H,215,255)(H,216,266)(H,217,267)(H,218,264)(H,219,272)(H,220,273)(H,221,278)(H,222,274)(H,223,276)(H,224,279)(H,225,242)(H,226,268)(H,227,271)(H,228,269)(H,229,270)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,280,281)(H,282,283)(H4,185,186,193)(H4,187,188,194)(H4,189,190,195)/t99-,100-,101-,102-,103+,104+,112-,114-,115-,116-,117-,118-,119-,120-,121-,122?,123?,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,146-,147-,148-,149-,150-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.213 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087737
(CHEMBL427943 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCC(CCCCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C166H254N42O50/c1-18-20-21-22-23-30-43-98(164(257)258)44-31-34-50-123(216)174-63-36-35-47-107(147(240)192-111(58-62-129(224)225)148(241)197-115(68-95-39-26-24-27-40-95)153(246)207-134(88(11)19-2)161(254)186-92(15)140(233)194-117(71-99-74-177-104-46-33-32-45-102(99)104)151(244)196-113(67-85(5)6)152(245)205-132(86(7)8)159(252)193-106(49-38-65-176-166(171)172)143(236)178-76-124(217)187-105(48-37-64-175-165(169)170)142(235)181-79-131(228)229)189-138(231)90(13)183-137(230)89(12)185-146(239)110(55-59-122(168)215)188-125(218)77-179-145(238)109(57-61-128(222)223)191-149(242)112(66-84(3)4)195-150(243)114(70-97-51-53-101(214)54-52-97)198-156(249)119(80-209)201-158(251)121(82-211)202-160(253)133(87(9)10)206-155(248)118(73-130(226)227)199-157(250)120(81-210)203-163(256)136(94(17)213)208-154(247)116(69-96-41-28-25-29-42-96)200-162(255)135(93(16)212)204-126(219)78-180-144(237)108(56-60-127(220)221)190-139(232)91(14)184-141(234)103(167)72-100-75-173-83-182-100/h24-29,32-33,39-42,45-46,51-54,74-75,83-94,98,103,105-121,132-136,177,209-214H,18-23,30-31,34-38,43-44,47-50,55-73,76-82,167H2,1-17H3,(H2,168,215)(H,173,182)(H,174,216)(H,178,236)(H,179,238)(H,180,237)(H,181,235)(H,183,230)(H,184,234)(H,185,239)(H,186,254)(H,187,217)(H,188,218)(H,189,231)(H,190,232)(H,191,242)(H,192,240)(H,193,252)(H,194,233)(H,195,243)(H,196,244)(H,197,241)(H,198,249)(H,199,250)(H,200,255)(H,201,251)(H,202,253)(H,203,256)(H,204,219)(H,205,245)(H,206,248)(H,207,246)(H,208,247)(H,220,221)(H,222,223)(H,224,225)(H,226,227)(H,228,229)(H,257,258)(H4,169,170,175)(H4,171,172,176)/t88-,89-,90-,91-,92-,93+,94+,98?,103-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,132-,133-,134-,135-,136-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0720 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087742
(CHEMBL411138 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)N1CCC(CC1)C(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O Show InChI InChI=1S/C173H267N43O49/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-53-133(227)216-71-66-105(67-72-216)148(242)181-68-41-40-50-114(155(249)199-118(61-65-136(232)233)156(250)204-122(75-102-44-33-31-34-45-102)161(255)214-141(95(11)19-2)169(263)193-99(15)147(241)201-124(78-106-81-184-111-49-39-38-48-109(106)111)159(253)203-120(74-92(5)6)160(254)212-139(93(7)8)167(261)200-113(52-43-70-183-173(178)179)151(245)185-83-130(224)194-112(51-42-69-182-172(176)177)150(244)188-86-138(236)237)196-145(239)97(13)190-144(238)96(12)192-154(248)117(58-62-129(175)223)195-131(225)84-186-153(247)116(60-64-135(230)231)198-157(251)119(73-91(3)4)202-158(252)121(77-104-54-56-108(222)57-55-104)205-164(258)126(87-217)208-166(260)128(89-219)209-168(262)140(94(9)10)213-163(257)125(80-137(234)235)206-165(259)127(88-218)210-171(265)143(101(17)221)215-162(256)123(76-103-46-35-32-36-47-103)207-170(264)142(100(16)220)211-132(226)85-187-152(246)115(59-63-134(228)229)197-146(240)98(14)191-149(243)110(174)79-107-82-180-90-189-107/h31-36,38-39,44-49,54-57,81-82,90-101,105,110,112-128,139-143,184,217-222H,18-30,37,40-43,50-53,58-80,83-89,174H2,1-17H3,(H2,175,223)(H,180,189)(H,181,242)(H,185,245)(H,186,247)(H,187,246)(H,188,244)(H,190,238)(H,191,243)(H,192,248)(H,193,263)(H,194,224)(H,195,225)(H,196,239)(H,197,240)(H,198,251)(H,199,249)(H,200,261)(H,201,241)(H,202,252)(H,203,253)(H,204,250)(H,205,258)(H,206,259)(H,207,264)(H,208,260)(H,209,262)(H,210,265)(H,211,226)(H,212,254)(H,213,257)(H,214,255)(H,215,256)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H4,176,177,182)(H4,178,179,183)/t95-,96-,97-,98-,99-,100+,101+,110-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,139-,140-,141-,142-,143-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.410 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087745
(CHEMBL439481 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCC(CCCCC(=O)NCCCCC(NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(O)=O)C(O)=O Show InChI InChI=1S/C173H268N46O51/c1-18-20-21-22-23-24-31-45-102(169(267)268)46-32-35-53-128(227)183-66-37-36-49-116(170(269)270)199-131(230)82-188-147(245)109(50-38-67-184-171(176)177)197-129(228)80-189-148(246)110(51-39-68-185-172(178)179)204-164(262)137(90(7)8)216-157(255)118(71-89(5)6)207-156(254)122(75-103-78-187-108-48-34-33-47-106(103)108)205-145(243)96(15)196-166(264)139(92(11)19-2)218-158(256)120(72-99-41-27-25-28-42-99)208-153(251)115(61-65-135(236)237)203-152(250)111(52-40-69-186-173(180)181)200-143(241)94(13)193-142(240)93(12)195-151(249)114(58-62-127(175)226)198-130(229)81-190-150(248)113(60-64-134(234)235)202-154(252)117(70-88(3)4)206-155(253)119(74-101-54-56-105(225)57-55-101)209-161(259)124(84-220)212-163(261)126(86-222)213-165(263)138(91(9)10)217-160(258)123(77-136(238)239)210-162(260)125(85-221)214-168(266)141(98(17)224)219-159(257)121(73-100-43-29-26-30-44-100)211-167(265)140(97(16)223)215-132(231)83-191-149(247)112(59-63-133(232)233)201-144(242)95(14)194-146(244)107(174)76-104-79-182-87-192-104/h25-30,33-34,41-44,47-48,54-57,78-79,87-98,102,107,109-126,137-141,187,220-225H,18-24,31-32,35-40,45-46,49-53,58-77,80-86,174H2,1-17H3,(H2,175,226)(H,182,192)(H,183,227)(H,188,245)(H,189,246)(H,190,248)(H,191,247)(H,193,240)(H,194,244)(H,195,249)(H,196,264)(H,197,228)(H,198,229)(H,199,230)(H,200,241)(H,201,242)(H,202,252)(H,203,250)(H,204,262)(H,205,243)(H,206,253)(H,207,254)(H,208,251)(H,209,259)(H,210,260)(H,211,265)(H,212,261)(H,213,263)(H,214,266)(H,215,231)(H,216,255)(H,217,258)(H,218,256)(H,219,257)(H,232,233)(H,234,235)(H,236,237)(H,238,239)(H,267,268)(H,269,270)(H4,176,177,184)(H4,178,179,185)(H4,180,181,186)/t92-,93-,94-,95-,96-,97+,98+,102?,107-,109-,110-,111-,112-,113-,114-,115-,116?,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,137-,138-,139-,140-,141-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.00600 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087746
(CHEMBL428139 | GLP-1(7-37) | Glucagon like peptide...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O Show InChI InChI=1S/C151H228N40O47/c1-17-77(10)121(148(236)169-81(14)127(215)177-105(60-87-63-160-92-36-25-24-35-90(87)92)138(226)179-101(56-74(4)5)139(227)188-119(75(6)7)146(234)176-94(37-26-28-52-152)130(218)161-65-111(199)170-93(39-30-54-159-151(156)157)129(217)164-68-118(210)211)190-140(228)103(57-84-31-20-18-21-32-84)180-135(223)99(47-51-116(206)207)175-134(222)95(38-27-29-53-153)172-125(213)79(12)166-124(212)78(11)168-133(221)98(44-48-110(155)198)171-112(200)66-162-132(220)97(46-50-115(204)205)174-136(224)100(55-73(2)3)178-137(225)102(59-86-40-42-89(197)43-41-86)181-143(231)107(69-192)184-145(233)109(71-194)185-147(235)120(76(8)9)189-142(230)106(62-117(208)209)182-144(232)108(70-193)186-150(238)123(83(16)196)191-141(229)104(58-85-33-22-19-23-34-85)183-149(237)122(82(15)195)187-113(201)67-163-131(219)96(45-49-114(202)203)173-126(214)80(13)167-128(216)91(154)61-88-64-158-72-165-88/h18-25,31-36,40-43,63-64,72-83,91,93-109,119-123,160,192-197H,17,26-30,37-39,44-62,65-71,152-154H2,1-16H3,(H2,155,198)(H,158,165)(H,161,218)(H,162,220)(H,163,219)(H,164,217)(H,166,212)(H,167,216)(H,168,221)(H,169,236)(H,170,199)(H,171,200)(H,172,213)(H,173,214)(H,174,224)(H,175,222)(H,176,234)(H,177,215)(H,178,225)(H,179,226)(H,180,223)(H,181,231)(H,182,232)(H,183,237)(H,184,233)(H,185,235)(H,186,238)(H,187,201)(H,188,227)(H,189,230)(H,190,228)(H,191,229)(H,202,203)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H4,156,157,159)/t77-,78-,79-,80-,81-,82+,83+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,119-,120-,121-,122-,123-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0550 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087734
(CHEMBL412115 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCC(CCCCC(=O)NCCCCC(NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(=O)OC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(O)=O)C(O)=O Show InChI InChI=1S/C170H262N46O51/c1-19-21-24-42-99(166(263)264)43-29-32-50-125(224)180-63-34-33-46-113(167(265)266)196-128(227)79-185-144(241)106(47-35-64-181-168(173)174)194-126(225)77-186-145(242)107(48-36-65-182-169(175)176)201-161(258)134(87(7)8)213-154(251)115(68-86(5)6)204-153(250)119(72-100-75-184-105-45-31-30-44-103(100)105)202-142(239)93(15)193-163(260)136(89(11)20-2)215-155(252)117(69-96-38-25-22-26-39-96)205-150(247)112(57-61-131(231)232)200-149(246)108(49-37-66-183-170(177)178)197-140(237)91(13)190-139(236)90(12)192-148(245)111(55-59-124(172)223)195-127(226)78-187-147(244)110(58-62-133(235)267-18)199-151(248)114(67-85(3)4)203-152(249)116(71-98-51-53-102(222)54-52-98)206-158(255)121(81-217)209-160(257)123(83-219)210-162(259)135(88(9)10)214-157(254)120(74-132(233)234)207-159(256)122(82-218)211-165(262)138(95(17)221)216-156(253)118(70-97-40-27-23-28-41-97)208-164(261)137(94(16)220)212-129(228)80-188-146(243)109(56-60-130(229)230)198-141(238)92(14)191-143(240)104(171)73-101-76-179-84-189-101/h22-23,25-28,30-31,38-41,44-45,51-54,75-76,84-95,99,104,106-123,134-138,184,217-222H,19-21,24,29,32-37,42-43,46-50,55-74,77-83,171H2,1-18H3,(H2,172,223)(H,179,189)(H,180,224)(H,185,241)(H,186,242)(H,187,244)(H,188,243)(H,190,236)(H,191,240)(H,192,245)(H,193,260)(H,194,225)(H,195,226)(H,196,227)(H,197,237)(H,198,238)(H,199,248)(H,200,246)(H,201,258)(H,202,239)(H,203,249)(H,204,250)(H,205,247)(H,206,255)(H,207,256)(H,208,261)(H,209,257)(H,210,259)(H,211,262)(H,212,228)(H,213,251)(H,214,254)(H,215,252)(H,216,253)(H,229,230)(H,231,232)(H,233,234)(H,263,264)(H,265,266)(H4,173,174,181)(H4,175,176,182)(H4,177,178,183)/t89-,90-,91-,92-,93-,94+,95+,99?,104-,106-,107-,108-,109-,110-,111-,112-,113?,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,134-,135-,136-,137-,138-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.00400 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087739
(CHEMBL441580 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCC(=O)NC(CCC(O)=O)C(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCNC(=O)C(CCC(O)=O)NC(=O)CCCCCCCCCCCCCCC)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(O)=O Show InChI InChI=1S/C193H302N42O55/c1-19-22-24-26-28-30-32-34-36-38-40-42-50-68-147(243)212-130(75-81-152(248)249)169(267)199-86-56-54-65-128(172(270)203-99-149(245)214-127(67-58-88-201-193(196)197)171(269)206-102-158(260)261)220-188(286)159(109(8)9)232-181(279)137(90-108(6)7)223-180(278)141(94-121-97-202-126-64-53-52-63-124(121)126)221-167(265)115(16)211-190(288)161(111(12)21-3)234-182(280)139(91-118-59-46-44-47-60-118)224-177(275)135(79-85-156(256)257)219-176(274)129(66-55-57-87-200-170(268)131(76-82-153(250)251)213-148(244)69-51-43-41-39-37-35-33-31-29-27-25-23-20-2)216-165(263)113(14)208-164(262)112(13)210-175(273)134(74-80-146(195)242)215-150(246)100-204-174(272)133(78-84-155(254)255)218-178(276)136(89-107(4)5)222-179(277)138(93-120-70-72-123(241)73-71-120)225-185(283)143(103-236)228-187(285)145(105-238)229-189(287)160(110(10)11)233-184(282)142(96-157(258)259)226-186(284)144(104-237)230-192(290)163(117(18)240)235-183(281)140(92-119-61-48-45-49-62-119)227-191(289)162(116(17)239)231-151(247)101-205-173(271)132(77-83-154(252)253)217-166(264)114(15)209-168(266)125(194)95-122-98-198-106-207-122/h44-49,52-53,59-64,70-73,97-98,106-117,125,127-145,159-163,202,236-241H,19-43,50-51,54-58,65-69,74-96,99-105,194H2,1-18H3,(H2,195,242)(H,198,207)(H,199,267)(H,200,268)(H,203,270)(H,204,272)(H,205,271)(H,206,269)(H,208,262)(H,209,266)(H,210,273)(H,211,288)(H,212,243)(H,213,244)(H,214,245)(H,215,246)(H,216,263)(H,217,264)(H,218,276)(H,219,274)(H,220,286)(H,221,265)(H,222,277)(H,223,278)(H,224,275)(H,225,283)(H,226,284)(H,227,289)(H,228,285)(H,229,287)(H,230,290)(H,231,247)(H,232,279)(H,233,282)(H,234,280)(H,235,281)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H,256,257)(H,258,259)(H,260,261)(H4,196,197,201)/t111-,112-,113-,114-,115-,116+,117+,125-,127-,128-,129-,130?,131?,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,159-,160-,161-,162-,163-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 16.7 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087731
(CHEMBL428330 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C174H269N43O51/c1-18-20-21-22-23-24-25-26-27-28-29-30-31-32-39-55-131(226)197-118(172(267)268)61-66-130(225)182-70-43-42-52-111(150(245)189-86-139(238)239)195-132(227)83-186-151(246)112(53-44-71-183-173(177)178)202-167(262)140(93(7)8)214-160(255)120(74-92(5)6)205-159(254)124(78-105-81-185-110-51-41-40-50-108(105)110)203-148(243)99(15)194-169(264)142(95(11)19-2)216-161(256)122(75-102-46-35-33-36-47-102)206-156(251)117(64-69-137(234)235)201-155(250)113(54-45-72-184-174(179)180)198-146(241)97(13)191-145(240)96(12)193-154(249)116(60-65-129(176)224)196-133(228)84-187-153(248)115(63-68-136(232)233)200-157(252)119(73-91(3)4)204-158(253)121(77-104-56-58-107(223)59-57-104)207-164(259)126(87-218)210-166(261)128(89-220)211-168(263)141(94(9)10)215-163(258)125(80-138(236)237)208-165(260)127(88-219)212-171(266)144(101(17)222)217-162(257)123(76-103-48-37-34-38-49-103)209-170(265)143(100(16)221)213-134(229)85-188-152(247)114(62-67-135(230)231)199-147(242)98(14)192-149(244)109(175)79-106-82-181-90-190-106/h33-38,40-41,46-51,56-59,81-82,90-101,109,111-128,140-144,185,218-223H,18-32,39,42-45,52-55,60-80,83-89,175H2,1-17H3,(H2,176,224)(H,181,190)(H,182,225)(H,186,246)(H,187,248)(H,188,247)(H,189,245)(H,191,240)(H,192,244)(H,193,249)(H,194,264)(H,195,227)(H,196,228)(H,197,226)(H,198,241)(H,199,242)(H,200,252)(H,201,250)(H,202,262)(H,203,243)(H,204,253)(H,205,254)(H,206,251)(H,207,259)(H,208,260)(H,209,265)(H,210,261)(H,211,263)(H,212,266)(H,213,229)(H,214,255)(H,215,258)(H,216,256)(H,217,257)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,238,239)(H,267,268)(H4,177,178,183)(H4,179,180,184)/t95-,96-,97-,98-,99-,100+,101+,109-,111-,112-,113-,114-,115-,116-,117-,118?,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,140-,141-,142-,143-,144-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.116 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087743
(CHEMBL410575 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCCC(NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(O)=O)C(O)=O Show InChI InChI=1S/C180H281N47O52/c1-18-20-21-22-23-24-25-26-27-28-29-30-31-32-39-57-135(236)206-122(177(278)279)63-68-134(235)190-72-43-42-53-121(176(276)277)207-138(239)88-195-154(254)114(54-44-73-191-178(183)184)204-136(237)86-196-155(255)115(55-45-74-192-179(185)186)212-171(271)144(96(7)8)224-164(264)124(77-95(5)6)215-163(263)128(81-108-84-194-113-52-41-40-51-111(108)113)213-152(252)102(15)203-173(273)146(98(11)19-2)226-165(265)126(78-105-47-35-33-36-48-105)216-160(260)120(66-71-142(245)246)211-159(259)116(56-46-75-193-180(187)188)208-150(250)100(13)200-149(249)99(12)202-158(258)119(62-67-133(182)234)205-137(238)87-197-157(257)118(65-70-141(243)244)210-161(261)123(76-94(3)4)214-162(262)125(80-107-58-60-110(233)61-59-107)217-168(268)130(90-228)220-170(270)132(92-230)221-172(272)145(97(9)10)225-167(267)129(83-143(247)248)218-169(269)131(91-229)222-175(275)148(104(17)232)227-166(266)127(79-106-49-37-34-38-50-106)219-174(274)147(103(16)231)223-139(240)89-198-156(256)117(64-69-140(241)242)209-151(251)101(14)201-153(253)112(181)82-109-85-189-93-199-109/h33-38,40-41,47-52,58-61,84-85,93-104,112,114-132,144-148,194,228-233H,18-32,39,42-46,53-57,62-83,86-92,181H2,1-17H3,(H2,182,234)(H,189,199)(H,190,235)(H,195,254)(H,196,255)(H,197,257)(H,198,256)(H,200,249)(H,201,253)(H,202,258)(H,203,273)(H,204,237)(H,205,238)(H,206,236)(H,207,239)(H,208,250)(H,209,251)(H,210,261)(H,211,259)(H,212,271)(H,213,252)(H,214,262)(H,215,263)(H,216,260)(H,217,268)(H,218,269)(H,219,274)(H,220,270)(H,221,272)(H,222,275)(H,223,240)(H,224,264)(H,225,267)(H,226,265)(H,227,266)(H,241,242)(H,243,244)(H,245,246)(H,247,248)(H,276,277)(H,278,279)(H4,183,184,191)(H4,185,186,192)(H4,187,188,193)/t98-,99-,100-,101-,102-,103+,104+,112-,114-,115-,116-,117-,118-,119-,120-,121?,122?,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,144-,145-,146-,147-,148-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.115 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087726
(CHEMBL409983 | Glucagon like peptide-1(GLP-1)analo...)Show SMILES CCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCCC(NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(C)C)C(O)=O)C(O)=O Show InChI InChI=1S/C176H273N47O52/c1-18-20-21-22-23-24-25-26-27-28-35-53-131(232)202-118(173(274)275)59-64-130(231)186-68-39-38-49-117(172(272)273)203-134(235)84-191-150(250)110(50-40-69-187-174(179)180)200-132(233)82-192-151(251)111(51-41-70-188-175(181)182)208-167(267)140(92(7)8)220-160(260)120(73-91(5)6)211-159(259)124(77-104-80-190-109-48-37-36-47-107(104)109)209-148(248)98(15)199-169(269)142(94(11)19-2)222-161(261)122(74-101-43-31-29-32-44-101)212-156(256)116(62-67-138(241)242)207-155(255)112(52-42-71-189-176(183)184)204-146(246)96(13)196-145(245)95(12)198-154(254)115(58-63-129(178)230)201-133(234)83-193-153(253)114(61-66-137(239)240)206-157(257)119(72-90(3)4)210-158(258)121(76-103-54-56-106(229)57-55-103)213-164(264)126(86-224)216-166(266)128(88-226)217-168(268)141(93(9)10)221-163(263)125(79-139(243)244)214-165(265)127(87-225)218-171(271)144(100(17)228)223-162(262)123(75-102-45-33-30-34-46-102)215-170(270)143(99(16)227)219-135(236)85-194-152(252)113(60-65-136(237)238)205-147(247)97(14)197-149(249)108(177)78-105-81-185-89-195-105/h29-34,36-37,43-48,54-57,80-81,89-100,108,110-128,140-144,190,224-229H,18-28,35,38-42,49-53,58-79,82-88,177H2,1-17H3,(H2,178,230)(H,185,195)(H,186,231)(H,191,250)(H,192,251)(H,193,253)(H,194,252)(H,196,245)(H,197,249)(H,198,254)(H,199,269)(H,200,233)(H,201,234)(H,202,232)(H,203,235)(H,204,246)(H,205,247)(H,206,257)(H,207,255)(H,208,267)(H,209,248)(H,210,258)(H,211,259)(H,212,256)(H,213,264)(H,214,265)(H,215,270)(H,216,266)(H,217,268)(H,218,271)(H,219,236)(H,220,260)(H,221,263)(H,222,261)(H,223,262)(H,237,238)(H,239,240)(H,241,242)(H,243,244)(H,272,273)(H,274,275)(H4,179,180,187)(H4,181,182,188)(H4,183,184,189)/t94-,95-,96-,97-,98-,99+,100+,108-,110-,111-,112-,113-,114-,115-,116-,117?,118?,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,140-,141-,142-,143-,144-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0540 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells |
J Med Chem 43: 1664-9 (2000)
BindingDB Entry DOI: 10.7270/Q2MK6C4P |
More data for this
Ligand-Target Pair | |
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