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Compile Data Set for Download or QSAR

Found 82 hits with Last Name = 'aikins' and Initial = 'ja'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475107
PNG
(CHEMBL179928)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C13H8Cl3NO3S/c14-8-1-4-10(5-2-8)21(19,20)17-13(18)11-6-3-9(15)7-12(11)16/h1-7H,(H,17,18)
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n/an/a 170n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475105
PNG
(CHEMBL189605)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Br)cc1Cl
Show InChI InChI=1S/C13H8BrCl2NO3S/c14-8-1-6-11(12(16)7-8)13(18)17-21(19,20)10-4-2-9(15)3-5-10/h1-7H,(H,17,18)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475147
PNG
(CHEMBL185804)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C14H11Cl2NO3S/c1-9-2-5-11(6-3-9)21(19,20)17-14(18)12-7-4-10(15)8-13(12)16/h2-8H,1H3,(H,17,18)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475104
PNG
(CHEMBL362085)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Br
Show InChI InChI=1S/C13H8BrCl2NO3S/c14-12-7-9(16)3-6-11(12)13(18)17-21(19,20)10-4-1-8(15)2-5-10/h1-7H,(H,17,18)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475152
PNG
(CHEMBL188975)
Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2ccc(Br)cc2)c(Cl)c1
Show InChI InChI=1S/C13H8BrCl2NO3S/c14-8-1-4-10(5-2-8)21(19,20)17-13(18)11-6-3-9(15)7-12(11)16/h1-7H,(H,17,18)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475139
PNG
(CHEMBL187192)
Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2cccc(Br)c2)c(Cl)c1
Show InChI InChI=1S/C13H8BrCl2NO3S/c14-8-2-1-3-10(6-8)21(19,20)17-13(18)11-5-4-9(15)7-12(11)16/h1-7H,(H,17,18)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475145
PNG
(CHEMBL187453)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Br)cc1Br
Show InChI InChI=1S/C13H8Br2ClNO3S/c14-8-1-6-11(12(15)7-8)13(18)17-21(19,20)10-4-2-9(16)3-5-10/h1-7H,(H,17,18)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475159
PNG
(CHEMBL189864)
Show SMILES Cc1cc(Cl)ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C14H11Cl2NO3S/c1-9-8-11(16)4-7-13(9)14(18)17-21(19,20)12-5-2-10(15)3-6-12/h2-8H,1H3,(H,17,18)
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n/an/a 300n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475122
PNG
(CHEMBL188715)
Show SMILES COc1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C14H11Cl2NO4S/c1-21-10-3-5-11(6-4-10)22(19,20)17-14(18)12-7-2-9(15)8-13(12)16/h2-8H,1H3,(H,17,18)
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n/an/a 350n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475146
PNG
(CHEMBL189138)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C17H17Cl2NO3S/c1-17(2,3)11-4-7-13(8-5-11)24(22,23)20-16(21)14-9-6-12(18)10-15(14)19/h4-10H,1-3H3,(H,20,21)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475124
PNG
(CHEMBL188687)
Show SMILES Cc1ccc(cc1Cl)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C14H10Cl3NO3S/c1-8-2-4-10(7-12(8)16)22(20,21)18-14(19)11-5-3-9(15)6-13(11)17/h2-7H,1H3,(H,18,19)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475121
PNG
(CHEMBL363735)
Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C13H7Cl3FNO3S/c14-7-1-3-9(10(15)5-7)13(19)18-22(20,21)8-2-4-12(17)11(16)6-8/h1-6H,(H,18,19)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475109
PNG
(CHEMBL185679)
Show SMILES Fc1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C13H8Cl2FNO3S/c14-8-1-6-11(12(15)7-8)13(18)17-21(19,20)10-4-2-9(16)3-5-10/h1-7H,(H,17,18)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475154
PNG
(CHEMBL187967)
Show SMILES Clc1cccc(c1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C13H8Cl3NO3S/c14-8-2-1-3-10(6-8)21(19,20)17-13(18)11-5-4-9(15)7-12(11)16/h1-7H,(H,17,18)
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n/an/a 440n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475108
PNG
(CHEMBL180882)
Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c(Cl)c1
Show InChI InChI=1S/C13H7Cl4NO3S/c14-7-1-3-9(11(16)5-7)13(19)18-22(20,21)8-2-4-10(15)12(17)6-8/h1-6H,(H,18,19)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475134
PNG
(CHEMBL181855)
Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C13H9Cl2NO3S/c14-9-6-7-11(12(15)8-9)13(17)16-20(18,19)10-4-2-1-3-5-10/h1-8H,(H,16,17)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475131
PNG
(CHEMBL364656)
Show SMILES CSc1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C14H11Cl2NO3S2/c1-21-10-3-5-11(6-4-10)22(19,20)17-14(18)12-7-2-9(15)8-13(12)16/h2-8H,1H3,(H,17,18)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475111
PNG
(CHEMBL186038)
Show SMILES CC(=O)c1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C15H11Cl2NO4S/c1-9(19)10-2-5-12(6-3-10)23(21,22)18-15(20)13-7-4-11(16)8-14(13)17/h2-8H,1H3,(H,18,20)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475123
PNG
(CHEMBL189072)
Show SMILES Cc1cc(Br)ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C14H11BrClNO3S/c1-9-8-10(15)2-7-13(9)14(18)17-21(19,20)12-5-3-11(16)4-6-12/h2-8H,1H3,(H,17,18)
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n/an/a 610n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475120
PNG
(CHEMBL187388)
Show SMILES [O-][N+](=O)c1ccc(C(=O)NS(=O)(=O)c2ccc(Cl)cc2)c(Cl)c1
Show InChI InChI=1S/C13H8Cl2N2O5S/c14-8-1-4-10(5-2-8)23(21,22)16-13(18)11-6-3-9(17(19)20)7-12(11)15/h1-7H,(H,16,18)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475151
PNG
(CHEMBL186218)
Show SMILES CCc1cc(Cl)ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C15H13Cl2NO3S/c1-2-10-9-12(17)5-8-14(10)15(19)18-22(20,21)13-6-3-11(16)4-7-13/h3-9H,2H2,1H3,(H,18,19)
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Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475136
PNG
(CHEMBL186516)
Show SMILES Cc1cccc(c1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C14H11Cl2NO3S/c1-9-3-2-4-11(7-9)21(19,20)17-14(18)12-6-5-10(15)8-13(12)16/h2-8H,1H3,(H,17,18)
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n/an/a 750n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475150
PNG
(CHEMBL365284)
Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2ccc(Br)c(Br)c2)c(Cl)c1
Show InChI InChI=1S/C13H7Br2Cl2NO3S/c14-10-4-2-8(6-11(10)15)22(20,21)18-13(19)9-3-1-7(16)5-12(9)17/h1-6H,(H,18,19)
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n/an/a 910n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475153
PNG
(CHEMBL365095)
Show SMILES [O-][N+](=O)c1cccc(c1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C13H8Cl2N2O5S/c14-8-4-5-11(12(15)6-8)13(18)16-23(21,22)10-3-1-2-9(7-10)17(19)20/h1-7H,(H,16,18)
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n/an/a 910n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475140
PNG
(CHEMBL426981)
Show SMILES COc1cccc(c1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C14H11Cl2NO4S/c1-21-10-3-2-4-11(8-10)22(19,20)17-14(18)12-6-5-9(15)7-13(12)16/h2-8H,1H3,(H,17,18)
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n/an/a 910n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475119
PNG
(CHEMBL187977)
Show SMILES CN(C)c1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C15H14Cl2N2O3S/c1-19(2)11-4-6-12(7-5-11)23(21,22)18-15(20)13-8-3-10(16)9-14(13)17/h3-9H,1-2H3,(H,18,20)
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n/an/a 930n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475103
PNG
(CHEMBL360177)
Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2cccc(c2)-c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C19H13Cl2NO3S/c20-15-9-10-17(18(21)12-15)19(23)22-26(24,25)16-8-4-7-14(11-16)13-5-2-1-3-6-13/h1-12H,(H,22,23)
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n/an/a 970n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475161
PNG
(CHEMBL186419)
Show SMILES COC(=O)c1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C15H11Cl2NO5S/c1-23-15(20)9-2-5-11(6-3-9)24(21,22)18-14(19)12-7-4-10(16)8-13(12)17/h2-8H,1H3,(H,18,19)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475133
PNG
(CHEMBL186420)
Show SMILES [O-][N+](=O)c1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C13H8Cl2N2O5S/c14-8-1-6-11(12(15)7-8)13(18)16-23(21,22)10-4-2-9(3-5-10)17(19)20/h1-7H,(H,16,18)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475155
PNG
(CHEMBL189671)
Show SMILES CCCc1cc(Cl)ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C16H15Cl2NO3S/c1-2-3-11-10-13(18)6-9-15(11)16(20)19-23(21,22)14-7-4-12(17)5-8-14/h4-10H,2-3H2,1H3,(H,19,20)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475143
PNG
(CHEMBL364873)
Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2ccc(cc2)-c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C19H13Cl2NO3S/c20-15-8-11-17(18(21)12-15)19(23)22-26(24,25)16-9-6-14(7-10-16)13-4-2-1-3-5-13/h1-12H,(H,22,23)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475114
PNG
(CHEMBL188382)
Show SMILES FC(F)(F)c1ccc(C(=O)NS(=O)(=O)c2ccc(Cl)cc2)c(c1)C(F)(F)F
Show InChI InChI=1S/C15H8ClF6NO3S/c16-9-2-4-10(5-3-9)27(25,26)23-13(24)11-6-1-8(14(17,18)19)7-12(11)15(20,21)22/h1-7H,(H,23,24)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475115
PNG
(CHEMBL186217)
Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2cc(Cl)cc(Cl)c2)c(Cl)c1
Show InChI InChI=1S/C13H7Cl4NO3S/c14-7-1-2-11(12(17)6-7)13(19)18-22(20,21)10-4-8(15)3-9(16)5-10/h1-6H,(H,18,19)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475112
PNG
(CHEMBL363071)
Show SMILES COc1cc(Cl)ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C14H11Cl2NO4S/c1-21-13-8-10(16)4-7-12(13)14(18)17-22(19,20)11-5-2-9(15)3-6-11/h2-8H,1H3,(H,17,18)
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n/an/a 2.00E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475125
PNG
(CHEMBL188611)
Show SMILES Cc1ccc(C(=O)NS(=O)(=O)c2ccc(Cl)cc2)c(C)c1
Show InChI InChI=1S/C15H14ClNO3S/c1-10-3-8-14(11(2)9-10)15(18)17-21(19,20)13-6-4-12(16)5-7-13/h3-9H,1-2H3,(H,17,18)
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n/an/a 2.70E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475135
PNG
(CHEMBL189040)
Show SMILES Nc1cc(Cl)ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C13H10Cl2N2O3S/c14-8-1-4-10(5-2-8)21(19,20)17-13(18)11-6-3-9(15)7-12(11)16/h1-7H,16H2,(H,17,18)
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n/an/a 3.20E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475106
PNG
(CHEMBL188610)
Show SMILES COc1ccc(cc1OC)S(=O)(=O)NC(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C15H13Cl2NO5S/c1-22-13-6-4-10(8-14(13)23-2)24(20,21)18-15(19)11-5-3-9(16)7-12(11)17/h3-8H,1-2H3,(H,18,19)
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n/an/a 3.90E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475157
PNG
(CHEMBL187505)
Show SMILES Fc1cc(Br)ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C13H8BrClFNO3S/c14-8-1-6-11(12(16)7-8)13(18)17-21(19,20)10-4-2-9(15)3-5-10/h1-7H,(H,17,18)
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n/an/a 4.60E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475137
PNG
(CHEMBL188430)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H8Cl3NO3S/c14-9-2-4-10(5-3-9)21(19,20)17-13(18)8-1-6-11(15)12(16)7-8/h1-7H,(H,17,18)
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n/an/a 5.90E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475128
PNG
(CHEMBL186209)
Show SMILES [O-][N+](=O)c1cc(Cl)ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C13H8Cl2N2O5S/c14-8-1-4-10(5-2-8)23(21,22)16-13(18)11-6-3-9(15)7-12(11)17(19)20/h1-7H,(H,16,18)
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n/an/a 5.90E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475113
PNG
(CHEMBL365275)
Show SMILES Clc1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C13H9Cl2NO3S/c14-10-3-1-9(2-4-10)13(17)16-20(18,19)12-7-5-11(15)6-8-12/h1-8H,(H,16,17)
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n/an/a 6.30E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475144
PNG
(CHEMBL188198)
Show SMILES COc1ccc(C(=O)NS(=O)(=O)c2ccc(Cl)cc2)c(Cl)c1
Show InChI InChI=1S/C14H11Cl2NO4S/c1-21-10-4-7-12(13(16)8-10)14(18)17-22(19,20)11-5-2-9(15)3-6-11/h2-8H,1H3,(H,17,18)
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n/an/a 9.90E+3n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475102
PNG
(CHEMBL189026)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)c1ccc(cc1Cl)C#N
Show InChI InChI=1S/C14H8Cl2N2O3S/c15-10-2-4-11(5-3-10)22(20,21)18-14(19)12-6-1-9(8-17)7-13(12)16/h1-7H,(H,18,19)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475110
PNG
(CHEMBL186707)
Show SMILES [O-][N+](=O)c1cc(ccc1C(=O)NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C14H8ClF3N2O5S/c15-9-2-4-10(5-3-9)26(24,25)19-13(21)11-6-1-8(14(16,17)18)7-12(11)20(22)23/h1-7H,(H,19,21)
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n/an/a 1.10E+4n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475160
PNG
(CHEMBL436085)
Show SMILES [O-][N+](=O)c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C13H9ClN2O5S/c14-10-3-7-12(8-4-10)22(20,21)15-13(17)9-1-5-11(6-2-9)16(18)19/h1-8H,(H,15,17)
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n/an/a 1.10E+4n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475149
PNG
(CHEMBL188572)
Show SMILES [O-][N+](=O)c1ccc(C(=O)NS(=O)(=O)c2ccc(Cl)cc2)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C13H8ClN3O7S/c14-8-1-4-10(5-2-8)25(23,24)15-13(18)11-6-3-9(16(19)20)7-12(11)17(21)22/h1-7H,(H,15,18)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475126
PNG
(CHEMBL188645)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)c1cc(Cl)ccc1Cl
Show InChI InChI=1S/C13H8Cl3NO3S/c14-8-1-4-10(5-2-8)21(19,20)17-13(18)11-7-9(15)3-6-12(11)16/h1-7H,(H,17,18)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475138
PNG
(CHEMBL188533)
Show SMILES Clc1ccc(C(=O)NS(=O)(=O)c2ccccc2Cl)c(Cl)c1
Show InChI InChI=1S/C13H8Cl3NO3S/c14-8-5-6-9(11(16)7-8)13(18)17-21(19,20)12-4-2-1-3-10(12)15/h1-7H,(H,17,18)
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n/an/a 1.40E+4n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475127
PNG
(CHEMBL189826)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)c1ccccc1Cl
Show InChI InChI=1S/C13H9Cl2NO3S/c14-9-5-7-10(8-6-9)20(18,19)16-13(17)11-3-1-2-4-12(11)15/h1-8H,(H,16,17)
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UniChem
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n/an/a 1.40E+4n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 1/2/3


(Homo sapiens (Human))
BDBM50475156
PNG
(CHEMBL359783)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C13H9Cl2NO3S/c14-10-4-6-12(7-5-10)20(18,19)16-13(17)9-2-1-3-11(15)8-9/h1-8H,(H,16,17)
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n/an/a 1.40E+4n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of vascular endothelial growth factor (VEGF)-stimulated human umbilical vein endothelial cell proliferation


J Med Chem 47: 5367-80 (2004)


Article DOI: 10.1021/jm030594r
BindingDB Entry DOI: 10.7270/Q2QR50W8
More data for this
Ligand-Target Pair
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