Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estrogen receptor (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Wilmington Curated by ChEMBL | Assay Description Binding affinity to estrogen receptor-alpha after 2 hrs by TR-FRET assay | Bioorg Med Chem 19: 5093-102 (2011) Article DOI: 10.1016/j.bmc.2011.07.026 BindingDB Entry DOI: 10.7270/Q23R0T8N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity of ERalpha LBD (unknown origin) incubated for 2 hrs by LanthaScreen TR-FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00615 BindingDB Entry DOI: 10.7270/Q2XW4PPQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50580157 (CHEMBL5071091) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.990 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity of ERalpha LBD (unknown origin) incubated for 2 hrs by LanthaScreen TR-FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00615 BindingDB Entry DOI: 10.7270/Q2XW4PPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50351197 (CHEMBL1818254) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity of ERalpha LBD (unknown origin) incubated for 2 hrs by LanthaScreen TR-FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00615 BindingDB Entry DOI: 10.7270/Q2XW4PPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50351197 (CHEMBL1818254) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Wilmington Curated by ChEMBL | Assay Description Binding affinity to estrogen receptor-alpha after 2 hrs by TR-FRET assay | Bioorg Med Chem 19: 5093-102 (2011) Article DOI: 10.1016/j.bmc.2011.07.026 BindingDB Entry DOI: 10.7270/Q23R0T8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50580158 (CHEMBL5072592) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity of ERalpha LBD (unknown origin) incubated for 2 hrs by LanthaScreen TR-FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00615 BindingDB Entry DOI: 10.7270/Q2XW4PPQ | |||||||||||
More data for this Ligand-Target Pair |